[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myocardial-blood-flow-reserve\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myocardial-blood-flow-reserve":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100590602","mechanical-dyssynchrony-and-microvascular-dysfunction-by-spect-100590602",false,"NCT06969547","Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT","Evaluation the Capabilities of Cardiac Mechanical Dyssynchrony in the Diagnosis of Myocardial Microvascular Dysfunction in Chronic Ischemic Heart Disease","MD&MD","Inclusion Criteria:\n\n* Ischemia with no obstructive coronary arteries (INOCA)\n* Obstructive coronary artery disease (CAD)\n* Patients without evidence of coronary heart disease\n\nExclusion Criteria:\n\n* Left ventricular ejection fraction \\\u003C55% according to echocardiography;\n* History of myocardial infarction\u002Frevascularization;\n* hypertension: systolic blood pressure \\>180 mm Hg. Art., diastolic BP\\>110 mm Hg. Art.;\n* systolic arterial hypotension \\\u003C80 mm Hg. Art.;\n* atrial fibrillation;\n* AV blockade of the III degree; sick sinus syndrome;\n* massive pulmonary embolism (PE) with a high degree of pulmonary hypertension;\n* the presence of significant valvular pathology (mitral insufficiency ≥ 3 degrees, aortic insufficiency ≥ 3 degrees, tricuspid regurgitation ≥ 3 degrees).\n* severe course of bronchial asthma, chronic obstructive pulmonary disease;\n* decompensated type 2 diabetes,\n* severe liver or kidney failure (glomerular filtration rate \\\u003C50 ml\u002Fmin\u002F1.73 m3 (CKD-EPI),\n* morbid obesity (body mass index \\>45);\n* history of myocarditis\n* indications of poor drug tolerance;\n* oncological diseases;\n* chronic alcoholism, mental disorders;\n* other severe comorbidity,\n* refusal to participate in the study.",true,"ALL","18 Years","75 Years",{"count":22,"type":23},75,"ESTIMATED","OBSERVATIONAL","The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary microvascular dysfunction in chronic coronary heart diseasу.",[27,28,29],"Myocardial Blood Flow Reserve","Mechanical Dyssynchrony","Coronary Arterial Disease (CAD)",[31,32,33,34,35],"SPECT","gated MPI","mechanical dyssynchrony","dobutamine","myocardial bloow flow reserve","RECRUITING","2025-09-22",{"date":39,"type":40},"2025-09-24","ACTUAL",{"date":42,"type":40},"2023-10-01",{"date":44,"type":23},"2026-05-15",{"name":46,"class":47},"Tomsk National Research Medical Center of the Russian Academy of Sciences","OTHER"]