[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myocardial-injury-after-noncardiac-surgery-mins\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myocardial-injury-after-noncardiac-surgery-mins":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,88,121,147,172,204],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100618701","prediction-model-for-mins-after-major-hepatobiliary-surgery-100618701",false,"NCT07335042","Prediction Model for MINS After Major Hepatobiliary Surgery","Development of an Interpretable Prediction Model for Myocardial Injury After Noncardiac Surgery in Patients Undergoing Major Hepatobiliary Surgery","Inclusion Criteria:\n\nAdults (18-85 yr, ASA physical status II-III) undergoing major hepatobiliary surgery were enrolled. Major surgery was defined as duration ≥ 3 h involving hepatectomy (≥ 3 segments) or biliary reconstruction necessitating ICU admission. Eligibility required paired perioperative high-sensitivity cardiac troponin T (hs-cTnT) data and comprehensive documentation of surgical covariates, including surgical approach (laparoscopic vs. open), resection nature (anatomic vs. non-anatomic), number of resected segments, tumor characteristics (size and location), and presence of cirrhosis.\n\nExclusion Criteria:\n\n(1) preoperative acute myocardial infarction, unstable angina, heart failure, or chronic kidney disease (estimated glomerular filtration rate \\\u003C 60 ml\u002F (min · 1.73 m2); (2) undocumented inflow occlusion strategy; or (3) non-imputable missing covariates.","ALL","18 Years","85 Years",{"count":20,"type":21},1800,"ESTIMATED","OBSERVATIONAL","This multi-center, prospective observational study aims to develop and validate an interpretable prediction model for Myocardial Injury After Noncardiac Surgery (MINS) in patients undergoing major hepatobiliary surgery. The study adopts a nested modeling strategy, starting with baseline risk factors (e.g., RCRI) and stepwise incorporating hepatic inflow occlusion strategies (specifically comparing SPVO vs. Pringle maneuver) and routine intraoperative biomarkers. The model's performance will be evaluated using AUC, Net Reclassification Improvement (NRI), and Decision Curve Analysis (DCA), followed by interpretability analysis using SHAP values and external validation in an independent cohort.",[25,26,27,28],"Myocardial Injury After Noncardiac Surgery (MINS)","Postoperative Complications","Liver Neoplasm","Hepatobiliary Diseases",[30,31,32,33,34,35,36],"MINS","Major Hepatobiliary Surgery","Hepatectomy","Hepatic Inflow Occlusion","Pringle Maneuver","Prediction Model","High-sensitivity Cardiac Troponin","RECRUITING","2026-06-12",{"date":40,"type":41},"2026-06-15","ACTUAL",{"date":43,"type":41},"2026-01-14",{"date":45,"type":21},"2027-06-30",{"name":47,"class":48},"Beijing Tsinghua Chang Gung Hospital","OTHER",6,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":71,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100577740","phase-4-the-choice-of-vasopressor-to-prevent-postoperative-acute-kidney-injury-after-major-non-cardiac-surgery-100577740","NCT06802224","The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery","Norepinephrine vs Phenylephrine as the First-line Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-cardiac Surgery","VEGA-2","Inclusion Criteria:\n\n* Age 18 years or older\n* Surgery under general anesthesia with a surgery duration of 2 hours or more\n* Received intravenous vasopressors during surgery\n\nExclusion Criteria:\n\n* Cardiac surgery\n* Extra-corporeal membrane oxygenation\n* Organ transplantation\n* Obstetric procedures\n* Procedures on the kidney\n* Outpatient procedures\n* Already receiving NE or PE or inotropes before induction of anesthesia (at the time of anesthesia start)\n* American Society of Anesthesiologists physical status classification 5 or 6\n* Patient for whom a local protocol recommends a specific first line vasopressor\n* Most recent documented estimated glomerular filtration rate (eGFR) \\\u003C 15 mL\u002Fmin\u002F1.73m\\^2 or preoperative renal replacement therapy within 60 days before surgery\n* Patients who do not have a preoperative creatinine value within 60 days before surgery\n* Alive patients who do not have a postoperative creatinine value",{"count":59,"type":21},18000,"INTERVENTIONAL",[62],"PHASE4","Low blood pressure, also known as hypotension, is very common during major surgery under general anesthesia. Prolonged or severe hypotension can lead to complications such as kidney injury after surgery that slow down patient recovery. Anesthesiologists commonly administer medications called vasopressors to treat low blood pressure during surgery. These medications help raise the blood pressure back up to a safe range. Two vasopressor medications are commonly used for this purpose: norepinephrine and phenylephrine. Each of these medications has slightly different effects on the heart and blood vessels (cardiovascular system). It remains unknown which of these standard medications is better for treating low blood pressure during surgery. The goal of this clinical trial is to determine which of these two medications is better at preventing injury to the kidneys after major noncardiac surgery as well as other complications such as heart problems. Major surgeries are defined as those lasting at least two hours under general anesthesia. This trial will randomize about ten centers in North America to use either norepinephrine or phenylephrine as the primary medication to treat low blood pressure in adults undergoing major noncardiac surgery. Each hospital will prioritize one of the drugs each month, and the assigned drug will rotate each month at each hospital. No further participant involvement will be required as de-identified data are collected as part of standard medical care.",[65,66,67,68,69,25,70],"Anesthesia","Surgery With General Anesthesia","Noncardiac Surgery","Hypotension During Surgery","Acute Kidney Injury (AKI)","Vasopressor",[72,73,74,75,76,77],"Norepinephrine","Phenylephrine","Major adverse kidney events","Pragmatic","Cluster randomized","Crossover","2026-05-20",{"date":80,"type":41},"2026-05-26",{"date":82,"type":41},"2025-04-01",{"date":84,"type":21},"2028-07",{"name":86,"class":48},"University of California, San Francisco",10,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":4,"studyType":60,"phases":101,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":116,"leadSponsor":118,"locationsCount":120},"100638404","phase-4-impact-of-propranolol-strategies-on-myocardial-injury-after-breast-cancer-surgery-100638404","NCT07583134","Impact of Propranolol Strategies on Myocardial Injury After Breast Cancer Surgery","A Pragmatic Clinical Trial to Evaluate the Impact of Clinical Propranolol Strategies on Myocardial Injury After Non-cardiac Surgery (MINS) in Patients Undergoing Breast Cancer Surgery With Hypertension or Angina","B-BIT","Inclusion Criteria:\n\n1. Female patients aged 20 to 70 years.\n2. Patients diagnosed with hypertension or angina who require medication.\n3. Patients diagnosed with unilateral, resectable primary breast cancer (ICD-10: C50), Stage I-III.\n4. ECOG performance status of 0-1.\n5. Patients scheduled to receive standard postoperative treatment (including adjuvant radiotherapy\n6. Patients who voluntarily decide to participate and sign the written informed consent form\n\nExclusion Criteria:\n\n1. Patients with distant metastases.\n2. Patients with active infectious diseases, autoimmune diseases (including specific rheumatic diseases), coagulation disorders, or cardiovascular diseases other than hypertension or angina pectoris.\n3. Patients with clinically significant hepatic, hematologic, or renal dysfunction, defined as any of the following:\n\n   ① ANC \\\u003C1,500\u002Fmm3\n   * Platelets \\\u003C100,000\u002Fmm3\n\n     * Hb \\\u003C9 g\u002FdL\n\n       * AST and ALT \\> 2.5 x upper limit of normal (ULN) ⑤ Alkaline phosphatase \\> 2.5 x ULN ⑥ Total bilirubin \\> 1 x ULN ⑦ Serum creatinine \\>1.5 x ULN or estimated creatinine clearance \\\u003C 60 mL\u002Fmin (as calculated using the method standard for the institution)\n4. Patients with moderate to severe asthma or chronic obstructive pulmonary disease (COPD).\n5. Patients who are pregnant or breastfeeding at the time of enrollment.\n6. Patients with a history of malignancy within the past 5 years.\n7. Patients for whom data collection is considered difficult at the discretion of the investigator.\n8. Patients who are unable to understand or complete study questionnaires.\n9. Patients who have received β-blockers within 30 days prior to screening.\n10. Patients with systolic blood pressure \\\u003C 100 mmHg or heart rate \\\u003C 55 beats per minute.","FEMALE","20 Years","70 Years",{"count":100,"type":21},100,[62],"This study aims to evaluate the impact of using propranolol, a non-selective beta-blocker, on preventing myocardial injury after non-cardiac surgery (MINS) in breast cancer patients who also have hypertension or angina. Stress from surgery and anesthesia can increase sympathetic activity and inflammation, which may lead to heart stress. This pragmatic clinical trial will compare patients who are prescribed propranolol as part of their routine care with those who are not. Researchers will analyze blood samples and surgical tissues collected during normal treatment to observe changes in heart health and the tumor microenvironment.",[104,25],"Breast Cancer",[106,107,108,109,110],"Propranolol","Breast Cancer Surgery","Beta-blockers","Tumor Microenvironment","Pragmatic Clinical Trial","NOT_YET_RECRUITING","2026-05-12",{"date":114,"type":41},"2026-05-15",{"date":80,"type":21},{"date":117,"type":21},"2033-05-24",{"name":119,"class":48},"Chang-Ik Yoon",1,{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":16,"minAge":128,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":131,"conditions":132,"keywords":4,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":146},"100616051","vascular-events-in-noncardiac-surgery-patients-cohort-evaluation-study-2-100616051","NCT07300579","Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2","VISION-2","Inclusion Criteria:\n\n1. age ≥65 years;\n2. underwent non-cardiac surgery with general, neuraxial, local, or regional anesthesia; and\n3. expected length of hospital stay of 3 or more days\n\nExclusion Criteria:\n\n1. hearing aid(s) or cochlear implant(s) in left ear;\n2. pacemaker\u002Fimplantable cardioverter-defibrillator (ICD);\n3. externally programmable cerebrospinal fluid shunt;\n4. deep brain stimulator;\n5. intolerance\u002Fallergy to adhesive;\n6. history of dementia, or;\n7. previous enrollment in the VISION-2 Study","65 Years",{"count":130,"type":21},20000,"VISION-2 is an international, multi-site, prospective observational cohort study of 20,000 patients undergoing noncardiac surgery. Continuous biometric data will be blindly collected for the first 30 postoperative days, in hospital and at home, using Vitaliti™. Following study enrollment and baseline data collection, follow up visits will occur in-hospital, at 30-days, and 1-year post-operatively.\n\nVISION-2 has 3 primary objectives, among participants who underwent noncardiac surgery, the investigators will: 1) determine the pattern and frequency of physiological precursors (i.e., biophysical signals) to MINS, BIMS, sepsis, and infection without sepsis; 2) build prediction models from these biophysical signals and their extracted features through supervised machine learning, for the prediction and early detection of those complications; and 3) build a biobank for evaluation of novel biomarkers.",[25,133,134,135,136],"Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS)","Sepsis","Infection Without Sepsis","Post-operative Complications","2026-04-09",{"date":139,"type":41},"2026-04-14",{"date":141,"type":21},"2026-06",{"date":143,"type":21},"2032-06",{"name":145,"class":48},"Hamilton Health Sciences Corporation",3,{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":154,"targetDuration":4,"studyType":60,"phases":155,"briefSummary":157,"conditions":158,"keywords":159,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":120},"100575111","secondary-prevention-and-management-of-myocardial-injury-after-noncardiac-surgery-synergy-pilot-trial-100575111","NCT06768034","SecondarY Prevention and maNagement of Myocardial Injury aftER Noncardiac surGerY (SYNERGY) Pilot Trial","A Pilot Pragmatic Randomized Controlled Trial Evaluating Secondary Cardiovascular Prevention Therapies in Patients Who Had a Myocardial Injury After Noncardiac Surgery to Prevent Major Cardiovascular Events","Inclusion Criteria:\n\n1. Have undergone noncardiac surgery,\n2. Had a myocardial injury after noncardiac surgery with a presumed ischemic mechanism and without an overt nonischemic precipitating etiology (e.g., sepsis)\n3. Provide written informed consent to participate in the SYNERGY pilot trial.\n\nExclusion Criteria:\n\n1. already on 2 of 3 secondary cardiovascular prevention medications (i.e., antiplatelet, statin, and\u002For angiotensin-converting enzyme inhibitor (ACEI)\u002Fangiotensin II receptor blocker (ARB)\n2. patients with contraindication to statins (i.e., decompensated or Child-Pugh C cirrhosis, acute liver failure, elevated AST\u002FALT greater than 2-fold the normal upper limit, previous demonstrated statin hypersensitivity, allergy, or statin-related myopathy);\n3. patients with contraindication to antiplatelet therapy (i.e., active or recent \\\u003C1-month peptic ulcer disease, esophageal or gastric variceal disease, history of intracranial or intraspinal hemorrhage, significant thrombocytopenia with platelet count \\\u003C50 × 109\u002FL),\n4. patients with contraindication to ACEI and ARB therapy (i.e, hypersensitivity or allergy to ACEI or ARB);\n5. Previously enrolled in the SYNERGY pilot trial,\n6. Considered unreliable or unable to complete the trial procedures.",{"count":100,"type":21},[156],"NA","Cardiac complications, particularly myocardial injury after noncardiac surgery (MINS), significantly contribute to 30-day mortality, affecting about 1 in 10 patients after noncardiac surgery. Despite its prevalence and serious implications, there is no consensus on managing myocardial injury after noncardiac surgery in clinical practice. Interventions commonly used for cardiovascular prevention in patients who had a heart attack outside of a surgery context could also be beneficial in patient with MINS. This pilot study trial aims to gather feasibility data, such as recruitment rates and intervention adherence that will guide on the design and inform on sample size of a future study with large pragmatic randomized controlled trial on the impact of systematic referral for secondary cardiovascular prevention on outcomes in patients who had a MINS.",[25],[160,161,162],"Noncardiac surgery","Secondary cardiovascular prevention","Randomized controlled trial","2026-03-17",{"date":165,"type":41},"2026-03-19",{"date":167,"type":21},"2026-04",{"date":169,"type":21},"2027-11",{"name":171,"class":48},"Centre hospitalier de l'Université de Montréal (CHUM)",{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":16,"minAge":178,"maxAge":4,"enrollmentInfo":179,"targetDuration":4,"studyType":60,"phases":181,"briefSummary":182,"conditions":183,"keywords":189,"overallStatus":111,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":4},"100588661","comparison-of-myocardial-injury-after-noncardiac-surgery-mins-incidence-in-supine-vs-prone-positioning-during-percutaneous-nephrolithotomy-pnl-100588661","NCT06944301","Comparison of Myocardial Injury After Noncardiac Surgery (MINS) Incidence in Supine vs. Prone Positioning During Percutaneous Nephrolithotomy (PNL)","Inclusion Criteria:\n\n* Age ≥40 years.\n* Patients undergoing percutaneous nephrolithotomy (PNL) for kidney stones.\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n* Known coronary artery disease, heart failure, or other significant cardiovascular conditions.\n* Elevated preoperative troponin levels (≥0.03 ng\u002FmL).\n* Major intraoperative complications (e.g., severe bleeding requiring transfusion).\n* Inability to comply with study procedures.","40 Years",{"count":180,"type":21},400,[156],"This prospective cohort study aims to compare the incidence of Myocardial Injury after Noncardiac Surgery (MINS) in patients undergoing percutaneous nephrolithotomy (PNL) for kidney stones in supine versus prone positioning. MINS is defined as an elevated postoperative troponin level (≥0.03 ng\u002FmL) within 48 hours after surgery. Approximately 400 patients will be enrolled, with 200 patients in each positioning group (supine and prone). The primary outcome is the incidence of MINS, assessed through troponin measurements and electrocardiogram (ECG) findings. Secondary outcomes include intraoperative complications, duration of surgery, and postoperative recovery metrics. The study seeks to determine whether surgical positioning impacts MINS risk, potentially guiding safer surgical practices.",[30,184,25,185,186,187,188],"Myocardial Injury After Noncardiac Surgery","Renal Calculi","Renal Stones","Percutaneous Nephrolithotomy (PNL)","Nephrolithiasis",[30,190,191,192,193,194],"PNL","percutaneous nephrolithotomy","Myocardial Injury after Noncardiac Surgery","prone","supine","2025-04-23",{"date":197,"type":41},"2025-04-25",{"date":199,"type":21},"2025-06-01",{"date":201,"type":21},"2026-08-01",{"name":203,"class":48},"Medipol University",{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":210,"eligibilityCriteria":211,"healthyVolunteers":212,"sex":16,"minAge":213,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":60,"phases":216,"briefSummary":218,"conditions":219,"keywords":224,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":120},"100537528","phase-3-colchicine-in-patients-at-cardiac-risk-undergoing-major-non-cardiac-surgery-100537528","NCT06279000","Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery","Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery: Prospective, Randomized, Double-blinded, Placebo-controlled, Multi-centre Study","COLCAT","Inclusion Criteria:\n\nundergoing major non-cardiac surgery in general anaesthesia will be included. Major non-cardiac surgery is defined as:\n\n* vascular surgery (with the exception of arteriovenous shunt, vein stripping procedures and carotid endarterectomies)\n* intraperitoneal surgery\n* intrathoracic surgery\n* major orthopaedic surgery (spinal surgery or joint replacement surgery)\n* at cardiovascular risk, defined as meeting at least 1 of the following 6 criteria:\n\n  * preoperative n-terminal pro brain natriuretic peptide (NT-proBNP) ≥ 200 ng\u002Fl\n  * history of coronary artery disease\n  * history of peripheral vascular disease\n  * history of stroke\n  * undergoing major vascular surgery, with the exception of arteriovenous shunt, vein stripping procedures and carotid endarterectomies\n  * fulfilment of any 3 of the 8 following criteria:\n\n    * undergoing major surgery (intrathoracic, intraperitoneal or supra-inguinal vascular surgery)\n    * any history of congestive heart failure or history of pulmonary oedema\n    * anamnestic transient ischemic attack (TIA)\n    * diabetes under treatment with either oral antidiabetic agent or insulin\n    * age \\> 70 years\n    * history of hypertension\n    * serum creatinine \\> 175 mumol\u002Fl or calculated creatinine clearance \\< 60 ml\u002Fmin\u002F1.73m2 (cockcroft gault)\n    * history of smoking within 2 years of surgery\n    * planned surgical time ≥ 90 minutes\n    * planned postoperative hospital stay at least 1 night\n\nExclusion Criteria:\n\n* no written consent\n* inclusion in other clinical trial with direct impact on perioperative medication\n* previously reported side effects or reported intolerance from colchicine (e.g., allergic reaction or significant sensitivity to colchicine or an auxiliary substance of the IMP)\n* pregnancy or planned pregnancy and\u002For breast feeding\n* clinically significant history of drug or alcohol abuse within the last year\n* very severe frailty (≥ 8 clinical frailty scale)\n* patient with inflammatory bowel disease (e.g., Morbus Crohn or Colitis ulcerosa)\n* patient taking colchicine for other indications (e.g., familial Mediterranean fever, gout)\n* severe renal impairment (eGFR \\< 30 ml min -1 1.73 m2 -1) or end-stage renal disease with indication for haemodialysis\n* history of solid organ or bone marrow transplantation\n* systemic immune-suppression (medication (steroids \\>30mg cortisol-equivalent per day, tacrolimus etc...) or disease (e.g., myelodysplastic syndrome)\n* severe hepatic impairment with history of cirrhosis\n* chronic active hepatitis or functional disorders defined as alanine aminotransferase greater than three times the upper limit of normal\n* anticipated post-operative administration of CYP3A4 metabolized substances like cyclosporine, ketoconazole, clarithromycin, verapamil, quinidine, diltiazem or ritonavir\n* Any other condition that the investigator would consider a risk to the patient if the latter were to participate in the study.",true,"45 Years",{"count":215,"type":21},880,[217],"PHASE3","Perioperative myocardial injury and major adverse cardiovascular events (MACE) are common causes of morbidity and mortality in patients at increased cardiovascular risk undergoing non-cardiac surgery.\n\nHowever, research in recent years has yielded limited preventive and therapeutic measures for myocardial injury\u002FMACE. Recent studies in patients with chronic and acute coronary artery disease have shown that colchicine administration can reduce the risk of cardiovascular events.\n\nThese encouraging results in non-surgical patients ask for a similar investigation in patients undergoing major non-cardiac surgery. The aim of the proposed study is to investigate the effects of perioperative colchicine administration on the incidence of myocardial injury\u002FMACE.",[220,221,222,223,25],"Cardiovascular Diseases","Cardiovascular Complication","Perioperative Complication","Myocardial Injury",[225,226,227,228],"Perioperative Cardiovascular Risk","myocardial injury","major adverse cardiac events","colchicine","2025-04-19",{"date":231,"type":41},"2025-04-24",{"date":233,"type":41},"2025-04-20",{"date":235,"type":21},"2029-03-30",{"name":237,"class":48},"Cantonal Hospital of St. Gallen"]