[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myofascial-pain-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myofascial-pain-syndrome":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,47,82,112,141,162,190,212,232],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100641578","focused-shockwave-therapy-for-neck-and-shoulder-myofascial-pain-100641578",false,"NCT07660523","Focused Shockwave Therapy for Neck and Shoulder Myofascial Pain","Effectiveness of Second-Generation Focused Extracorporeal Shockwave Therapy Combined With Ultrasonographic Assessment in Myofascial Pain Syndrome of the Neck and Shoulder: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults older than 20 years.\n* Clinical diagnosis of nonspecific neck and shoulder pain primarily arising from muscles and soft tissues in the upper trapezius or levator scapulae region, as determined by a physical medicine and rehabilitation physician.\n* Neck and shoulder pain lasting for at least 3 months.\n* Neck Disability Index score greater than 5.\n* No use of analgesic medication or muscle relaxants within the previous month.\n* No injection therapy, physical therapy, or other treatment for neck and shoulder pain within the previous month.\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Neck or shoulder pain caused by a neurologic disorder, including cervical radiculopathy.\n* Clinical or imaging diagnosis of cervical degenerative joint disease.\n* History of a rheumatic disease, including rheumatoid arthritis or systemic lupus erythematosus.\n* History of head or neck trauma.\n* History of cervical spine surgery.\n* History of whiplash injury.\n* Pregnancy.\n* Current or previous malignancy considered clinically relevant to shockwave therapy.\n* Bleeding disorder.\n* Current use of anticoagulant medication, including warfarin.\n* Acute inflammation or infection at the treatment site.\n* Implanted cardiac pacemaker or implantable cardioverter-defibrillator.\n* Any other condition judged by the study physician to make participation or focused shockwave therapy inappropriate or unsafe.","ALL","20 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Myofascial pain syndrome of the neck and shoulder is a common condition characterized by persistent muscle pain, tenderness, stiffness, and limitations in daily activities. Focused extracorporeal shockwave therapy is a noninvasive treatment that may reduce pain and improve muscle function. However, additional clinical evidence is needed regarding the effectiveness of second-generation focused shockwave therapy and whether ultrasound imaging can objectively detect changes in muscle function after treatment.\n\nThis pilot randomized controlled trial will enroll 60 adults with chronic neck and shoulder myofascial pain syndrome. Participants will be randomly assigned to either a focused shockwave therapy group or a home-based neck exercise group.\n\nParticipants in the focused shockwave therapy group will receive one treatment session per week for three consecutive weeks. Participants in the control group will perform a standardized home exercise program designed to improve neck mobility and reduce muscle tightness.\n\nAssessments will be performed before the intervention, after the intervention, and at follow-up. Study outcomes will include pain intensity measured using the Visual Analogue Scale, neck-related disability measured using the Neck Disability Index, pressure pain threshold measured using an algometer, and upper trapezius muscle thickness and contraction-related changes measured using ultrasound imaging.\n\nThe primary objective is to determine whether focused shockwave therapy is more effective than a home-based neck exercise program in reducing pain and improving neck function. The study will also evaluate whether ultrasound-derived muscle measurements are associated with changes in pain, pressure sensitivity, and functional disability.",[26],"Myofascial Pain Syndrome",[26,28,29,30,31,32,33,34],"Focused Extracorporeal Shockwave Therapy","Neck and Shoulder Pain","Upper Trapezius Muscle","Pressure Pain Threshold","Ultrasound Imaging","Muscle Thickness","Neck Disability","NOT_YET_RECRUITING","2026-06-19",{"date":38,"type":39},"2026-06-24","ACTUAL",{"date":41,"type":20},"2026-07-13",{"date":43,"type":20},"2027-05-30",{"name":45,"class":46},"Cishan Hospital, Ministry of Health and Welfare","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":59,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100642778","acute-effect-of-diaphragmatic-breathing-on-postoperative-upper-trapezius-pain-100642778","NCT07634588","ACUTE EFFECT OF DIAPHRAGMATIC BREATHING ON POSTOPERATIVE UPPER TRAPEZIUS PAIN","EVALUATION OF THE ACUTE EFFECTS OF DIAPHRAGMATIC BREATHING EXERCISES ADDED TO SOFT TISSUE MOBILIZATION AND PERCUSSIVE THERAPY ON PAIN, FUNCTIONALITY, AND PRESSURE PAIN THRESHOLD IN THE UPPER TRAPEZIUS MUSCLE OF SURGICAL NURSES AFTER SURGERY","TRAP-BREATHE","Inclusion Criteria:\n\n* Aged between 22 and 55 years.\n* Operating room nurse actively working in the hospital operating theater.\n* Reporting upper trapezius pain and tenderness within 30 minutes after completion of a surgical procedure.\n* Willing to participate and able to provide written informed consent.\n\nExclusion Criteria:\n\n* History of trauma, surgery, or chronic disease affecting the neck or shoulder region.\n* Regular participation in breathing exercise programs.\n* Psychiatric disorders requiring anxiolytic or antidepressant medication.\n* Pregnancy.\n* Skin disease, infection, or open wound in the treatment area.\n* Severe cardiovascular disease or uncontrolled hypertension.\n* Contraindications to manual therapy, soft tissue mobilization, percussive therapy, or breathing exercises.","22 Years","55 Years",{"count":58,"type":20},38,[23],"This randomized controlled trial aims to investigate the acute effects of diaphragmatic breathing exercises added to soft tissue mobilization and percussive therapy on pain intensity, functional disability, and pressure pain threshold in operating room nurses experiencing upper trapezius pain after surgery-related work activities.\n\nParticipants will be operating room nurses working in a hospital operating theater who report upper trapezius pain and tenderness within 30 minutes after completing a surgical procedure. Eligible participants will be randomly assigned to either an intervention group receiving soft tissue mobilization, percussive therapy, and diaphragmatic breathing exercises, or a control group receiving soft tissue mobilization and percussive therapy alone.\n\nPain intensity will be assessed using the Visual Analog Scale (VAS), functional disability using the Neck Disability Index (NDI), and mechanical pain sensitivity using Pressure Pain Threshold (PPT) measurements. Assessments will be performed immediately before and after a single treatment session. The study aims to determine whether the addition of diaphragmatic breathing exercises provides additional benefits in reducing pain and improving function in the acute postoperative working period of operating room nurses.",[62,26,63],"Neck Pain","Work-Related Musculoskeletal Disorders",[65,66,67,68,69,31,70,71,72],"Upper Trapezius Pain","Diaphragmatic Breathing","Soft Tissue Mobilization","Percussive Therapy","Operating Room Nurses","Neck Disability Index","Musculoskeletal Pain","Acute Pain","2026-06-05",{"date":75,"type":39},"2026-06-09",{"date":73,"type":20},{"date":78,"type":20},"2026-08",{"name":80,"class":46},"Istanbul Aydın University",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":21,"phases":93,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":81},"100632289","comparison-of-three-treatment-modalities-in-myofascial-pain-syndrome-100632289","NCT07511751","COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME","COMPARATIVE EFFECTIVENESS OFF DRY NEEDLING, EXTRACORPOREAL SHOCK WAVE THERAPY, AND TRANSCUTANEOUS PULSED RADIOFREQUENCY IN PATIENTS WITH MYOFASCIAL PAIN SYNDROME: A PROSPECTIVE, RANDOMIZED CONTROLLED TRIAL","MPS-TREAT","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Clinically diagnosed myofascial pain syndrome\n* Back pain lasting at least 3 months\n* Failure to respond to conservative treatments\n\nExclusion Criteria:\n\n* History of cervical surgery or cervical disc pathology\n* Fibromyalgia\n* Shoulder pathologies\n* Coagulation disorders or use of anticoagulant therapy\n* Infection, malignancy, or inflammatory spinal diseases","18 Years","65 Years",{"count":19,"type":20},[23],"This study aims to compare the effectiveness of dry needling, extracorporeal shock wave therapy (ESWT), and pulsed radiofrequency (PRF) in patients with chronic musculoskeletal pain. The primary outcomes include pain intensity and functional status. Patients will be randomly assigned to different treatment groups, and outcomes will be evaluated before and after the interventions. The results of this study are expected to contribute to determining the most effective treatment method for pain management.",[26],[97,98,99,100,101],"myofascial pain syndrome","dry needling","ESWT","pulsed radiofrequency","pain","RECRUITING","2026-05-01",{"date":105,"type":39},"2026-05-07",{"date":107,"type":39},"2026-03-10",{"date":109,"type":20},"2027-03-10",{"name":111,"class":46},"ALİEMAN",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":21,"phases":121,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":81},"100637041","effectiveness-of-tele-rehabilitation-in-managing-rhomboid-trigger-points-in-patients-with-myofascial-pain-syndrome-100637041","NCT07573527","Effectiveness of Tele-Rehabilitation in Managing Rhomboid Trigger Points in Patients With Myofascial Pain Syndrome","Inclusion Criteria:\n\n* Participants falling in this category would be recruited into the study.\n\n  * Age 18-35 years\n  * Both Genders: Male and Female\n  * Paitents experiencing Neck and upper back pain due to active trigger points.(16) According to Travell and Simons (1999)criteria, active myofascial trigger points (MTrPs) are identified.\n  * NPRS ≥4\n  * Presence of maximum one or more than one MTrPs in the Romboids muscle.\n  * Prolong sitting at least 6 hours per day.\n  * Access to a device with internet connection ( for tele rehabilitation group).\n\nExclusion Criteria:\n\n* Participants falling in this category would be excluded from the study.\n\n  * Participants fall in this category would be excluded of the study.\n  * Patients currently taking analgesics (painkillers) or muscle relaxants.\n  * Any inflammatory pathology, neurological impairment, and cervical tumor.\n  * Other deformities such as scoliosis or torticollis.\n  * Spinal Injuries and any other co morbidity.\n  * Any surgery, trauma, fracture and fall.\n  * Pregnancy.\n  * Patient unwilling to comply follow up schedule.\n  * Patient involvement in another interventional study.","35 Years",{"count":120,"type":20},36,[23],"This randomized controlled trial aims to assess the effectiveness of tele-rehabilitation, including self-myofascial release and exercise therapy, in reducing pain, improving functional range of motion, and decreasing neck disability in patients with rhomboid trigger points associated with myofascial pain syndrome.",[26],[125,126,127,128,62,129,130,131,132],"Tele-rehabilitation","Myofascial Release","Self-Myofascial Release,","Rhomboid Trigger Points","Postural Correction","cervical retraction","scapular retraction","Upper Trapezius & Levator Scapulae Stretch","2026-04-30",{"date":105,"type":39},{"date":136,"type":20},"2026-05",{"date":138,"type":20},"2027-01",{"name":140,"class":46},"Riphah International University",{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":21,"phases":151,"briefSummary":152,"conditions":153,"keywords":4,"overallStatus":102,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":160,"locationsCount":81},"100602111","effectiveness-of-prp-pharmacopuncture-for-chronic-neck-pain-in-cervical-myofascial-syndrome-of-the-upper-trapezius-100602111","NCT07119255","Effectiveness of PRP Pharmacopuncture for Chronic Neck Pain in Cervical Myofascial Syndrome of the Upper Trapezius","The Effectiveness of Pharmacopuncture With Platelet-Rich Plasma (PRP) as a Treatment for Chronic Neck Pain in Cervical Myofascial Syndrome Related to the Upper Trapezius Muscle","Inclusion Criteria:\n\n* Male or female, aged 18 to 59 years.\n* Experiencing neck pain for more than 3 months (chronic).\n* Neck pain classified as Grade I to III according to the Neck Pain Task Force classification.\n* Presence of referred pain pattern on physical examination consistent with the distribution of the upper trapezius muscle.\n* Visual Analogue Scale (VAS) score between 30 and 70 mm (out of 100 mm) during activity (e.g., daily activities or light exercise).\n* Willing to participate in the study until completion and has signed the informed consent form.\n\nExclusion Criteria:\n\n* Hemoglobin level \\\u003C13 g\u002FdL for males or \\\u003C12 g\u002FdL for females.\n* Platelet count \\\u003C150,000\u002FμL.\n* Presence of fever (≥37.5°C).\n* Diagnosis of fibromyalgia.\n* Structural abnormalities of the cervical spine other than degenerative changes, such as fractures, cervical spine injuries, space-occupying lesions (SOL), infections, neoplasms, or systemic diseases confirmed by radiographic imaging.\n* History of cervical spine surgery.\n* Presence of tumors, wounds, or skin infections at the needle insertion site.\n* Diagnosed with blood disorders or currently taking anticoagulant or antiplatelet medications.\n* History of hypersensitivity reactions to acupuncture (e.g., metal allergy, severe atopy, keloids, or other skin hypersensitivities).\n* Uncontrolled cardiovascular disease or diabetes mellitus.\n* History of pharmacopuncture therapy to the upper trapezius muscle within the past 6 months.\n* Use of anti-inflammatory medication within the past 2 weeks.\n* Currently pregnant or breastfeeding.","59 Years",{"count":150,"type":20},72,[23],"The goal of this clinical trial is to learn whether pharmacopuncture with Platelet-Rich Plasma (PRP) is effective for treating chronic neck pain in cervical myofascial syndrome related to the upper trapezius muscle. The main questions it aims to answer are:\n\n1. Is pharmacopuncture with Platelet-Rich Plasma (PRP) effective in reducing chronic neck pain in patients with cervical myofascial syndrome related to the upper trapezius muscle?\n2. Does PRP pharmacopuncture improve functional outcomes and quality of life in these patients?\n3. Are there any adverse effects associated with PRP pharmacopuncture in this context?\n\nResearchers will compare PRP pharmacopuncture to normal saline pharmacopuncture (placebo) to evaluate whether PRP provides greater effectiveness in reducing chronic neck pain in cervical myofascial syndrome related to the upper trapezius muscle.\n\nParticipants will:\n\n* Receive a single session of pharmacopuncture therapy\n* Undergo evaluations at week 2, week 4, and week 8 after the intervention",[62,26],"2026-04-13",{"date":156,"type":39},"2026-04-16",{"date":158,"type":39},"2025-09-01",{"date":78,"type":20},{"name":161,"class":46},"Indonesia University",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":168,"eligibilityCriteria":169,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":170,"enrollmentInfo":171,"targetDuration":4,"studyType":21,"phases":173,"briefSummary":174,"conditions":175,"keywords":176,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":4},"100623324","comparison-of-integrated-neuromuscular-inhibition-technique-init-and-active-release-technique-art-in-patients-with-upper-trapezius-trigger-points-100623324","NCT07395154","Comparison of Integrated Neuromuscular Inhibition Technique (INIT) and Active Release Technique (ART) in Patients With Upper Trapezius Trigger Points","COMPARATIVE EFFECT OF INTEGRATED NEUROMUSCULAR INHIBITION TECHNIQUE AND ACTIVE RELEASE TECHNIQUE ON PAIN, RANGE OF MOTION AND FUNCTIONAL DISABILITY IN PATIENTS WITH UPPER TRAPEZIUS TRIGGER POINTS","INIT ART","Inclusion Criteria:\n\n* Presence of active trigger points in the upper trapezius muscle.\n* Forward Head Posture (measured by craniovertebral angle).\n* Pain duration less than 3 months.\n\nExclusion Criteria:\n\n* History of trauma or surgery involving the cervical spine or shoulder\n* Neurological disorders (e.g., cervical radiculopathy)\n* Systemic conditions like diabetes or rheumatoid arthritis\n* Use of corticosteroids\n* Fibromyalgia, Thoracic Outlet Syndrome, Temporomandibular Joint Disorders","40 Years",{"count":172,"type":20},64,[23],"The goal of this clinical trial is to determine whether two manual therapy techniques-Integrated Neuromuscular Inhibition Technique (INIT) and Active Release Technique (ART)-can reduce pain, improve neck range of motion, and decrease functional disability in adults with upper trapezius myofascial trigger points.\n\nThe main questions it aims to answer are:\n\nDoes INIT reduce pain, improve ROM, and reduce functional disability more effectively than ART?\n\nDoes ART provide similar or different treatment benefits compared to INIT?\n\nResearchers will compare INIT with ART to see which technique produces greater improvements in pain, ROM, and functional disability.\n\nParticipants will:\n\nReceive treatment sessions of either INIT or ART.\n\nUndergo assessment of pain, cervical range of motion, and functional disability before and after the intervention.",[26],[177,178,179,180],"Integrated Neuromuscular Inhibition Technique","Active Release Technique","Muscle Energy Technique","Ischemic Compression","2026-02-03",{"date":183,"type":39},"2026-02-09",{"date":185,"type":20},"2026-02-15",{"date":187,"type":20},"2026-06-30",{"name":189,"class":46},"Lahore University of Biological and Applied Sciences",{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":4,"enrollmentInfo":197,"targetDuration":4,"studyType":21,"phases":199,"briefSummary":201,"conditions":202,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":4},"100591083","phase-2-magnesium-sulfate-and-trigger-points-100591083","NCT06975813","Magnesium Sulfate and Trigger Points","Efficacy of Isolated Masseter Versus Masseter- Sternocleidomastoid Trigger Points Injection by Magnesium Sulfate for Myofacial Pain","Inclusion Criteria:\n\n* definite diagnosis of myofascial pain\n* presence of one or more unilateral or bilateral trigger points in the masseter muscle and sternocleidomastoid muscle;\n* no history of any invasive procedures of the related masseter muscle.\n\nExclusion Criteria:\n\n* any painful conditions (other than myofascial trigger points) affecting the orofacial region\n* any systemic diseases that could masticatory function (e.g., rheumatoid arthritis and epilepsy);\n* pregnancy and lactation",{"count":198,"type":20},30,[200],"PHASE2","The patients will be randomly assigned to one of the two groups according to the treatment method: group I (masseter group) and group II (masseter \\&sternocleidomastoid group) where each patient will be injected 0.5ml in each trigger point (TrPs) of magnesium sulphate according to the treatment group by the same operator. The treatment method for TrPs will be the primary predictor variable. Patients will be examined at the following intervals: during diagnosis, 1-month, 3-months, and 6-months post-injection. The participated patients will be assessed using pain score measured on a 10-point visual analogue scale (VAS), the 0 indicating no pain and 10 indicating the worst pain ever",[26],"2025-05-09",{"date":205,"type":39},"2025-05-16",{"date":207,"type":20},"2025-06-01",{"date":209,"type":20},"2026-01-27",{"name":211,"class":46},"Fayoum University",{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":11,"sex":16,"minAge":218,"maxAge":90,"enrollmentInfo":219,"targetDuration":4,"studyType":21,"phases":221,"briefSummary":222,"conditions":223,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":228,"leadSponsor":230,"locationsCount":81},"100581066","effect-of-shock-wave-therapy-on-myofascial-pain-syndrome-in-adolescent-athletes-100581066","NCT06845475","Effect of Shock Wave Therapy on Myofascial Pain Syndrome in Adolescent Athletes","Inclusion Criteria:\n\n* Age ranges from 14 to 18 years.\n* All adolescents have regional pain complaint.\n* Tenderness in cervical trigger points in the midpoint of the upper border of the trapezius muscle, from grade 2 to grade 4 according to the tenderness grading scheme (Hubbard, 1993) (Appendix II).\n* Palpation of a trigger point elicits a stereotypic zone of referred pain specific to that muscle.\n* Identification of a palpable taut band, as well as a palpable, and exquisitely tender spot along the length of that taut band.\n* All adolescents are allowed to practice their regular sports activities.\n\nExclusion Criteria:\n\n* Dermatological disorders.\n* Having myofascial trigger points injection.\n* Chronic pain in both sides of the body.\n* History of findings of cervical injury whether orthopedic or soft tissue injury.\n* Analgesic drugs or NSAIDs during the treatment period.","14 Years",{"count":220,"type":20},40,[23],"The purpose of the study is to determine the effect of extracorporeal shockwave therapy on pain, neck range of motion, and functional activity in adolescent athletes.",[26],"2025-02-20",{"date":226,"type":39},"2025-02-25",{"date":226,"type":20},{"date":229,"type":20},"2025-05-05",{"name":231,"class":46},"Cairo University",{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":11,"sex":16,"minAge":90,"maxAge":239,"enrollmentInfo":240,"targetDuration":4,"studyType":21,"phases":242,"briefSummary":243,"conditions":244,"keywords":245,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":249,"lastUpdatePostDateStruct":250,"startDateStruct":252,"completionDateStruct":254,"leadSponsor":256,"locationsCount":4},"100557485","pilot-mri-study-on-osteopathic-manipulation-for-myofascial-pain-syndrome-100557485","NCT06538727","Pilot MRI Study on Osteopathic Manipulation for Myofascial Pain Syndrome","A Feasibility and Pilot Study of an MRI Study to Investigate Changes After Osteopathic Manipulation Therapy in Patients With Myofascial Pain Syndrome","Inclusion Criteria:\n\n* MPS of the upper back with MTrPs as specified by Travell and Simons, with the confirmation of ultrasound procedure.\n* Normal neurological examination including manual muscle testing, sensory exam, and deep tendon reflexes.\n* English-speaking.\n* Age 18 - 64 and reside in the community.\n\nExclusion Criteria:\n\n* Malignancy.\n* Major psychiatric disorders, such as bipolar disorder and depression.\n* Cognitive impairment\n* Skin lesion(s) on the shoulders and upper back.\n* Systematic pain condition, such as Fibromyalgia.\n* Previous surgical procedures in the spine, shoulder, and\u002For back within six months.\n* Pregnancy.\n* BMI of 40 or higher.\n* Any health conditions that prevent participants from performing the experimental procedure\n* Any contraindications of MRI procedure such as implantable cardiac devices (pacemakers, defibrillator, etc.), aneurysm clips, or metallic shoulder and\u002For spinal cord implants or screws.","64 Years",{"count":241,"type":20},20,[23],"The goal of this clinical trial is to conduct MRI studies on adults with myofascial pain syndrome (MPS) to identify important MRI biomarkers that respond to OMT (osteopathic manipulation therapy) and investigate the feasibility of implementing MRI study and OMT in this population. The main outcomes of the study include:\n\n* Determine whether biomarkers measured by MRI can differentiate normal tissues and MTrP (myofascial trigger point).\n* Test the responsiveness of the biomarkers identified by MRI to the proposed intervention, OMT, in patients with MPS of the upper back.\n\nResearchers will compare participants who will receive one session of OMT (Group 1 - Experimental Condition) and participants who will not receive any treatment (Group 2 - Control Condition) to see how the MRI-identified biomarkers respond to the intervention.\n\nParticipants will complete the following:\n\n* Clinical screening\n* MRI measures\n* Battery of self-report surveys\n* Clinical\u002FPhysical Function Assessment",[26],[246,247,26,248],"Myofascial Pain","MPS","Myofascial Trigger Point","2024-07-31",{"date":251,"type":39},"2024-08-06",{"date":253,"type":20},"2024-08-31",{"date":255,"type":20},"2025-06-30",{"name":257,"class":46},"Auburn University"]