[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myofascial-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myofascial-pain":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,67,96,118],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100614359","magnetic-resonance-elastography-to-monitor-response-to-manual-therapy-in-myofascial-pain-100614359",false,"NCT07278570","Magnetic Resonance Elastography to Monitor Response to Manual Therapy in Myofascial Pain","Inclusion Criteria:\n\n* Adult males or females (age ≥ 18 years)\n* A history of chronic low back for at least 3 months. (Measured by patient history and physical exam)\n* A palpable taut band or nodule within the skeletal muscle\n* Hypersensitive tender spot within the taut band\n* Recognition of current pain complaint by pressure on the tender nodule\u002Ftaut band\n* Painful limit to the full stretch range of motion\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n* Any contraindication to an MRI exam, or severe claustrophobia that would prevent safe completion of the scan\n* Previous therapy in the area to be treated within 3 months\n* Previous severe back injury (including fracture) or surgery\n* Any neurological conditions or active systemic disease (e.g. diabetes, peripheral vascular disease, cancer, rheumatoid arthritis) that impaired sensation\u002Fpain perception\n* Severe osteoarthritis\n* Skin injuries in the area to be treated\n* Inability to provide consent.","ALL","18 Years",{"count":18,"type":19},78,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this research is to develop and test new Magnetic Resonance Imaging (MRI) methods that look at how muscles and tissues under the skin (myofascial tissues) move and respond to pressure. The investigators want to see how these tissues differ between healthy people and people with pain or injury, and how they change after hands-on treatment (Tuina therapy). The results will also be compared to a group that receives standard care without Tuina therapy.\n\nThe main questions this study aims to answer are:\n\n1. Can MR elastography (MRE) show changes in how the fascia and the layers between muscles move and stretch before and after manual therapy?\n2. Do changes seen on MRE scans match changes in pain, function, and other symptoms reported by participants?\n3. Can MRE measurements before treatment help predict which participants are most likely to improve with manual therapy?\n\nIn this randomized controlled trial, participants with myofascial pain will be randomly assigned (randomized) to either the Tuina group or the Usual Care group following a home-based care program without manual therapy. All treatments are noninvasive, hands-on techniques commonly used in clinical practice to reduce tissue tightness and improve movement.\n\nParticipants will be asked to undergo three MRI scans and to complete questionnaires and other standard clinical assessments about their pain, physical function, and quality of life.",[25,26],"Myofascial Pain Syndrome - Lower Back","Myofascial Pain","RECRUITING","2026-02-02",{"date":30,"type":31},"2026-02-03","ACTUAL",{"date":33,"type":31},"2026-02-01",{"date":35,"type":19},"2027-08-30",{"name":37,"class":38},"Mayo Clinic","OTHER",2,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":20,"phases":50,"briefSummary":51,"conditions":52,"keywords":53,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":66},"100617732","multi-modal-imaging-of-myofascial-pain---phase-2-100617732","NCT07322445","Multi-modal Imaging of Myofascial Pain - Phase 2","Development and Identification of Magnetic Resonance, Electrophysiological, and Fiber-optic Imaging Biomarkers of Myofascial Pain","Inclusion Criteria:\n\n1. Adults between the ages of 18 and 80 years old.\n2. History of spontaneous (non-provoked) pain in the neck and\u002For shoulder region lasting at least 3 months. Neck and\u002For shoulder pain, unilateral or bilateral.\n3. Presence of a palpable myofascial trigger point (MTrP) in one or both upper trapezius muscles.\n4. The participant has a Numeric Pain Rating Scale of 4\u002F10 or more in the last one week, and the pain is reproducible by palpating the trigger point.\n5. Pain localized to the area of the trigger point that is reproduced or worsened upon palpation.\n6. Radiation of pain to the head, neck, or face with palpation is allowed but not required.\n\nExclusion Criteria:\n\n1. Age \\\u003C18 or \\>80 years old.\n2. Acute cervical spine pathology, trauma (e.g. whiplash) or cervical radiculopathy\n3. History of surgery involving the head, neck, or shoulder girdle.\n4. Presence of neuromuscular pathologies or inflammatory muscle diseases (e.g. dermatomyositis)\n5. Systemic disease with diffuse body pain (e.g. system lupus erythematosus)\n6. Peripheral neuropathy\n7. Cancer-related pain\n8. Pregnancy, coagulopathy or other bleeding disorder, fever, general\u002Flocal infection at the pain site, substance abuse, or any other diseases that may account for signs and symptoms mimicking myofascial pain.\n9. Contraindication to MRI\n10. Chronic fatigue syndrome, fibromyalgia, or chronic Lyme disease.\n11. Use of acupuncture or changes in pain medications within 6 weeks of enrollment.\n12. Receipt of Botox injection to the neck\u002Fshoulder region within the past 3 months or trigger point injection within the past 6 weeks.","80 Years",{"count":49,"type":19},100,[22],"The goal of this study is to evaluate imaging biomarkers for quantitative assessments of myofascial pain and determine their ability to monitor treatment response and predict clinical outcomes.",[26],[54,55,56],"Magnetic Resonance Imaging","Surface Electromyography","Fiber-optic Imaging and Sensing","2026-01-05",{"date":59,"type":31},"2026-01-07",{"date":61,"type":31},"2025-10-01",{"date":63,"type":19},"2027-12",{"name":65,"class":38},"Washington University School of Medicine",1,{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":47,"enrollmentInfo":74,"targetDuration":4,"studyType":20,"phases":76,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":66},"100610355","effects-of-core-strengthening-exercises-for-treating-tmd-100610355","NCT07226505","Effects of Core Strengthening Exercises for Treating TMD","A Randomized Trial Analyzing the Effects of Core Strengthening Exercises in Physical Therapy for Treating Temporomandibular Joint Dysfunction","Who Can Participate (Inclusion Criteria):\n\nAdults between 18 and 70 years old.\n\nHave had jaw pain or problems with the jaw joint (TMD) in the last 30 days.\n\nAble and willing to attend at least six physical therapy sessions over three months.\n\nSpeak English or have access to a qualified interpreter.\n\nAble to safely do physical exercises.\n\nWho Cannot Participate (Exclusion Criteria):\n\nRecently had surgery on the jaw, teeth, or spine (within the last 3 months).\n\nRecently had head or neck injuries or certain neurological problems (such as dizziness, double vision, trouble swallowing, or sudden falls).\n\nAre pregnant or become pregnant during the study.\n\nCurrently doing physical therapy for other movement problems that could affect the study.\n\nHave had lower back or pelvic health issues in the last 3 months.\n\nCurrently receiving chemotherapy or radiation for cancer in the head, neck, pelvis, spine, or hip.\n\nWear dentures or cannot safely perform exercises.",{"count":75,"type":19},50,[22],"Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education. Core strengthening (also known as abdominal strengthening) is a fundamental element of physical therapy that engages deep and superficial trunk musculature to enhance postural control and functional performance. Protocols such as the Shirley Sahrmann progression have demonstrated increased activation of key core stabilizing muscles. Emerging evidence suggests a potential relationship between core stability training and reductions in TMD-related pain, though improvements in functional outcomes remain inconclusive. Biomechanical links between the pelvic floor, spine, and temporomandibular joint further support the rationale for core-focused interventions. Nevertheless, few studies have isolated the effects of core strengthening on TMD symptomatology. This study seeks to determine whether the integration of core stability exercises into TMD management can reduce pain, improve function, and enhance quality of life.",[79,80,81,26],"Temporomandibular Joint Dysfunction","TMD","TMJ Internal Derangement",[83,84,85],"Core strengthening","physical therapy","RCT","NOT_YET_RECRUITING","2025-11-07",{"date":89,"type":31},"2025-11-10",{"date":91,"type":19},"2025-11-01",{"date":93,"type":19},"2027-01-31",{"name":95,"class":38},"Loyola University",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":20,"phases":106,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":4},"100581491","the-effects-of-ultrasound-guided-prf-versus-dn-in-myofascial-pain-patients-100581491","NCT06851000","The Effects of Ultrasound-guided PRF Versus DN in Myofascial Pain Patients","The Effects of Ultrasound-guided Pulsed Radiofrequemcy Versus Dry Needling in Myofascial Pain Patients","Inclusion Criteria:\n\n* Age 18-70 years old, gender unlimited.\n* Myofascial pain diagnosed according to the \"Simons and Travell\" criteria.\n* Able to complete treatment and follow-up.\n* Signed inform consent form.\n\nExclusion Criteria:\n\n* History of surgery, trauma, or infection in the pain area.\n* Severe systemic disease, e.g. malignant tumor; severe hepatic, renal, or coagulation disorder; etc.\n* Pregnancy, needle phobia, unable to cooperate.\n* Concurrently receiving pain treatment in other institutions.","70 Years",{"count":105,"type":19},68,[22],"This study aims to compare the effects of pulsed radiofrequency and drying needling and explore the short-term effect of pulsed radiofrequency in treating myofascial pain patients.",[26],"2025-03-04",{"date":111,"type":31},"2025-03-07",{"date":113,"type":19},"2025-02-25",{"date":115,"type":19},"2026-03-25",{"name":117,"class":38},"Peking Union Medical College Hospital",{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":125,"sex":15,"minAge":16,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":20,"phases":129,"briefSummary":130,"conditions":131,"keywords":132,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":66},"100556572","effectiveness-of-telerehabilitation-in-individuals-with-temporomandibular-joint-dysfunction-and-myofascial-pain-100556572","NCT06526845","Effectiveness of Telerehabilitation in Individuals With Temporomandibular Joint Dysfunction and Myofascial Pain","Examining The Effectiveness of Telerehabilitation in Individuals With Temporomandibular Joint Dysfunction and Myofascial Pain","Inclusion Criteria:\n\n* People between the ages of 18-65 with myofascial temporomandibular pain\n* Displacement of the disc with anterior reduction,\n* Pain in the masticatory muscle\u002Ftemporomandibular area lasting more than a month\n* Symptoms lasting at least three months,\n* People who have the opportunity to provide informed consent and participate in treatment and evaluation clinics.\n\nExclusion Criteria:\n\n* Anterior disc displacement without reduction,\n* Primary arthrogenic pain,\n* Other temporomandibular disorders,\n* Neurological or psychiatric disorders,\n* People who have had temporomandibular joint and\u002For cervical spine surgery,\n* Abuse of painkillers or abuse of existing medication.",true,"65 Years",{"count":128,"type":19},40,[22],"Telerehabilitation is a treatment method that allows the patient to access treatment remotely, regardless of where they are, thanks to developing technology. Telerehabilitation provides us with opportunities such as patient evaluation, monitoring, therapy, consultation, education and patient follow-up. Within the scope of our study, the effects of applying an exercise program to patients through a home exercise program and telerehabilitation will be investigated. The purpose of this study for individuals with temporomandibular joint dysfunction is; To investigate the effectiveness of exercises for myofascial pain through telerehabilitation in individuals with myofascial pain and TMJ dysfunction.",[79,26],[133,134,135],"Temporomandibular Joint Disorders","Telerehabilitation","Exercise","2024-07-24",{"date":138,"type":31},"2024-07-30",{"date":140,"type":19},"2024-07-23",{"date":142,"type":19},"2024-12-30",{"name":144,"class":38},"Biruni University"]