[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myopathies\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myopathies":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,54,92],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100631615","muscle-health-measurements-using-electrical-impedance-myography-100631615",false,"NCT07502989","Muscle Health Measurements Using Electrical Impedance Myography","Convenient Quantification of Myopathic Change in Muscle Via Electrical Impedance Myography","Inclusion Criteria:\n\n* Ages 18-89\n* Evidence of a primary myopathic condition as determined by detailed chart review, including results of genetic testing, serological data, or previous muscle biopsy\n\nExclusion Criteria:\n\n* Inability to lie flat or history of claustrophobia\n* \\>1+ lower extremity edema\n* Presence of multiple other pathologies affecting lower extremity muscles to be studied\n* Pregnancy\n* Contraindications for MRI scanning - e.g. MRI incompatible pacemaker, deep brain stimulator, or lower extremity hardware\n* Contraindications to undergo DXA Scan\n\n  * Any studies\u002Fscans with a radioisotope within the past 15 days\n  * Any imaging with radiographic contrast in the past 7 days\n  * Weight greater than 450 lbs\n  * Calcium supplements or antacids containing calcium in the past 24 hours\n* Severe obesity with BMI \\> 35 kg\u002Fm2, given difficulties fitting in MRI scanner and impact of severe obesity on EIM data\n* Chronic skin conditions with ulcerations which would interfere with EIM electrode contact or be uncomfortable for the participant",true,"ALL","18 Years","89 Years",{"count":21,"type":22},150,"ESTIMATED","1 Day","OBSERVATIONAL","This study is being done to further develop a device, the mScan, to measure muscle health as compared to measurements of muscle health using MRI (magnetic resonance imaging). This device is held against the skin and uses Electrical Impedance Myography (EIM). EIM uses a very small, noninvasive (e.g. no needles), brief (about 6 seconds), and painless electrical current to measure the muscle. The investigators will look at how the mScan predicts the muscle measurements seen on MRI in people with and without muscle disease. The investigators hope that this can be used in the future as a quick, convenient and less time-consuming way than MRI to assess muscle health. This could be used to measure how well treatments for different muscle disorders are working over a period of time.",[27,28,29,30,31,32,33],"Myopathy","Muscular Dystrophies","Myositis","Myofibrillar Myopathy","Congenital Myopathy","Distal Myopathy","Myopathies",[35,27,36,37,38,39,40],"Muscle Health","Device","Healthy control","MRI","Electrical Impedance Myography","EIM","RECRUITING","2026-03-30",{"date":44,"type":45},"2026-04-03","ACTUAL",{"date":47,"type":45},"2025-04-09",{"date":49,"type":22},"2027-09",{"name":51,"class":52},"Beth Israel Deaconess Medical Center","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":60,"targetDuration":62,"studyType":24,"phases":4,"briefSummary":63,"conditions":64,"keywords":80,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":53},"100630525","natural-history-study-for-patients-with-nemaline-myopathy-in-spain-100630525","NCT07488806","Natural History Study for Patients With Nemaline Myopathy in Spain","Inclusion Criteria:\n\n* Patients with a confirmed clinical and genetic diagnosis of MN (mutations in ACTA1, NEB, TPM2, TPM3, KBTBD13, CFL2, KLHL40, KLHL41, LMOD3, MYPN, TNNT1, TNNT3), or under discussion if they only have a compatible biopsy.\n* Signed informed consent by the patient or Legal Authority Responsible, and\u002For assent by the subject (in pediatric population).",{"count":61,"type":22},100,"5 Years","The objective of this natural history study is to comprehensively characterize the disease progression and clinical features of nemaline myopathies. The study aims to establish a well-defined cohort of patients in Spain, enabling long-term follow-up and facilitating recruitment for future clinical trials.",[65,33,66,67,68,69,70,71,72,73,74,75,76,77,78,79],"Nemaline Myopathy","Myopathic Conditions","NEB","ACTA1","TPM2","TPM3","TNNT1","CFL2","KBTBD13","KLHL40","KLHL41","LMOD3","Cohort Studies","MYPN","TNNT3",[81,82],"NATURAL HISTORY","NEMALINE MYOPATHY","2026-03-18",{"date":85,"type":45},"2026-03-23",{"date":87,"type":22},"2026-06",{"date":89,"type":22},"2032-06",{"name":91,"class":52},"Hospital Universitari Vall d'Hebron Research Institute",{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":102,"conditions":103,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":115},"100567332","observational-study-to-observe-variations-of-gait-parameters-in-patients-with-neuromuscular-diseases-100567332","NCT06666816","Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases","Observational Study for the Identification of Fatigue and Gait Biomarkers in Populations With Neuromuscular Pathologies in the Clinical Context and Daily Life","Inclusion Criteria:\n\n* Ambulant adult patients with genetic diagnosis of muscular dystrophy\u002Fmyopathy (dystrophinopathies, muscular dystrophies and congenital and non-congenital myopathies), of spinal muscular atrophy (SMA) and with molecular diagnosis of Charcot-Marie Tooth 1 or 2.\n* independent walking, even with assistance;\n\nExclusion Criteria:\n\n* Dilated or ischemic heart disease with moderate impairment;\n* Chronic respiratory failure: forced vital capacity (FVC) \\\u003C 40%; more than 5% of nocturnal time spent with peripheral oxygen saturation levels \\\u003C 90.","75 Years",{"count":101,"type":22},120,"This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases. Furthermore, the investigators want to evaluate the feasibility of collecting physical activity in daily life conditions during a one-week monitoring period using a wearable sensor.",[28,33,104,105],"Spinal Muscular Atrophy (SMA)","Charcot Marie Tooth Disease","2026-01-15",{"date":108,"type":45},"2026-01-20",{"date":110,"type":45},"2017-10-27",{"date":112,"type":22},"2026-12",{"name":114,"class":52},"IRCCS Eugenio Medea",2]