[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nalbuphine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nalbuphine":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100601404","nalbuphine-versus-tramadol-on-post-operative-analgesia-in-abdominal-surgery-on-pediatric-cancer-patient-100601404",false,"NCT07110051","Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer Patient","Comparative Study Between Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer Patient","Inclusion Criteria:\n\n* Participants will be children aged 3-12 years\n* American society of anesthesia (ASA) classification I-III.\n* scheduled for elective Abdominal surgery under general anesthesia\n\nExclusion Criteria:\n\n* child guardian refusal.\n* Allergy from Tramal or nalbuphine\n* Patient with previous chronic pain on opioids","ALL","3 Years","12 Years",{"count":20,"type":21},128,"ESTIMATED","INTERVENTIONAL",[24],"NA","In current study the investigators aim to compare between nalbuphine versus tramadol for post-operative pain control in abdominal surgeries in pediatric.",[27,28,29,30],"Tramadol","Nalbuphine","Abdominal Surgeries","Pediatric Cancer","RECRUITING","2025-08-06",{"date":34,"type":35},"2025-08-11","ACTUAL",{"date":37,"type":35},"2025-01-15",{"date":39,"type":21},"2025-10-15",{"name":41,"class":42},"National Cancer Institute, Egypt","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":61,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100593697","nalbuphine-dosing-and-its-impact-on-anxiety-and-depression-in-ectopic-pregnancy-surgery-100593697","NCT07009808","Nalbuphine Dosing and Its Impact on Anxiety and Depression in Ectopic Pregnancy Surgery","Effects of Different Doses of Nalbuphine on Anxiety and Depression in Patients Undergoing Ectopic Pregnancy Surgery: A Prospective, Randomized, Controlled Study","Inclusion Criteria:\n\n1. Confirmed diagnosis of ectopic pregnancy, aged ≥18 years, and with normal psychological status.\n2. Patients planned to undergo single-port laparoscopic surgery under general anesthesia, followed by postoperative patient-controlled intravenous analgesia (PCIA).\n3. Patients classified as ASA I or II.\n4. Able to understand the study process and methods, voluntarily participate, and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Patients using other analgesic methods or multiple analgesic approaches.\n2. Patients with a history of allergies or allergies to anesthetic drugs.\n3. Patients with a history of depression or mental illness.\n4. Patients with other severe organ dysfunction.\n5. Patients unable to operate the intravenous analgesia pump independently.","FEMALE","18 Years",{"count":54,"type":21},165,[24],"This prospective, randomized, controlled study aims to evaluate the impact of different doses of nalbuphine on anxiety and depression in patients undergoing surgery for ectopic pregnancy. Ectopic pregnancy, which occurs in approximately 2% of all pregnancies, often requires surgical intervention, leading to potential psychological distress such as anxiety and depression in affected women. Effective postoperative pain management is essential to enhance recovery and reduce emotional disturbances.\n\nThe study will involve 165 eligible patients diagnosed with ectopic pregnancy at Jinjiang District Maternal and Child Health Hospital. Participants will be randomly assigned to three groups, each receiving a different concentration of nalbuphine combined with metoclopramide for postoperative analgesia. The primary outcome will focus on changes in anxiety and depression scores measured on postoperative day three, while secondary outcomes will assess pain levels, the use of patient-controlled analgesia (PCA), the necessity for rescue analgesics, and the occurrence of adverse reactions.\n\nSample size calculations suggest that at least 165 participants are required to achieve adequate statistical power. Data will be analyzed using SPSS 25.0 software, with results expected to provide insights into the effectiveness of nalbuphine in improving postoperative recovery and mental health in women experiencing ectopic pregnancy. The study has received ethical approval and is funded by the Chengdu Medical Research Projects (No. 2023465, 2022548, and 2023304).",[58,59,60,28],"Ectopic Pregnancy","Anxiety","Depression",[58,59,60,28],"NOT_YET_RECRUITING","2025-06-06",{"date":65,"type":35},"2025-06-08",{"date":67,"type":21},"2025-06-20",{"date":69,"type":21},"2025-10-30",{"name":71,"class":42},"Chengdu Jinjiang Maternity and Child Health Hospital"]