[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nasal-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nasal-surgery":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100642447","remifentanil-vs-nicardipine-for-controlled-hypotension-in-elective-nasal-surgery-100642447",false,"NCT07660562","Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery","Comparison of Remifentanil and Nicardipine Infusions for Controlled Hypotension in Elective Nasal Surgery Where Bleeding Control is Critical: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age \\> 18 years\n* ASA physical status I-II\n* Scheduled for elective nasal surgery\n* No known serious cardiovascular, respiratory, renal, or hepatic disease\n* No known allergy to remifentanil or nicardipine\n* No chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents\n* Not pregnant or breastfeeding\n* BMI ≤ 35 kg\u002Fm²\n* No emergency surgical indication\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* ASA III or above\n* Known serious cardiovascular, respiratory, renal, or hepatic disease\n* Known allergy to remifentanil or nicardipine\n* Chronic use of beta-blockers, calcium channel blockers, or antihypertensive agents\n* Pregnancy or breastfeeding\n* Morbid obesity (BMI \\> 35 kg\u002Fm²)\n* Emergency surgery\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},44,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods. The study evaluates hemodynamic stability, surgical field quality (Fromme-Boezaart score), tissue perfusion, intraoperative blood loss, surgeon satisfaction, and perioperative adverse effects.",[26,27,28],"Nasal Surgery","Anesthesia","Controlled Hypotension for Nasal Surgeries","NOT_YET_RECRUITING","2026-06-16",{"date":32,"type":33},"2026-06-22","ACTUAL",{"date":35,"type":20},"2026-06-25",{"date":37,"type":20},"2026-07-15",{"name":39,"class":40},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100617386","lateral-crural-steal-with-columellar-strut-graft-in-primary-open-rhinoplasty-100617386","NCT07317947","Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty","The Effect of Lateral Crural Steal With Columellar Strut Graft on Nasal Tip Projection and Rotation in Primary Open Rhinoplasty","LCS\u002FCS","Inclusion Criteria:\n\n* Patients seeking primary rhinoplasty for aesthetic and\u002For functional indications.\n* Presence of inadequate nasal tip projection and\u002For rotation suitable for correction using lateral crural steal with columellar strut graft.\n* Ability to provide written informed consent and comply with follow-up visits.\n\nExclusion Criteria:\n\n* History of prior nasal surgery.\n* History of severe nasal trauma, altering cartilage architecture.\n* Significant functional nasal obstruction requiring complex external nasal valve reconstruction.\n* Patients with excessively wide alar base requiring alar base reduction involving vestibular sill excision (to prevent confounding on projection\u002Frotation).\n* Patients with facial skeletal or developmental abnormalities e.g. maxillary hypoplasia, maxillary prognathism, dentofacial deformities.\n* Patients with psychiatric illness or Body Dysmorphic Disorder.\n* Significant medical comorbidities contraindicating elective surgery or general anesthesia.\n* Inability to provide informed consent or comply with follow-up.","60 Years",{"count":51,"type":20},22,[23],"The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.",[55,26,56],"Rhinoplasty","Aesthetic Outcomes",[55,58,59,60,61],"Lateral crural steal","Columellar strut","Rhinobase","Rhinoplasty Outcome Evaluation","RECRUITING","2026-01-08",{"date":65,"type":33},"2026-01-09",{"date":67,"type":33},"2026-01-05",{"date":69,"type":20},"2027-02",{"name":71,"class":40},"Kafrelsheikh University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":72},"100461202","phase-4-pain-control-for-undergoing-costal-cartilage-harvesting-100461202","NCT05285566","Pain Control for Undergoing Costal Cartilage Harvesting","A Phase IV Randomized, Single-Blind Trial of Liposomal Bupivacaine (Exparel®) for Pain Control in Costal Cartilage Harvest","Inclusion Criteria:\n\n* Diagnosis of functional nasal obstruction or aesthetic nasal concern requiring nasal surgery with costal cartilage harvest.\n* Willing and able to understand and provide written informed consent.\n\nExclusion Criteria:\n\n* Known pregnancy.\n* Women who are currently nursing a child.\n* History of coagulopathy; such as hemophilia or Von Willebrand disease, or any congenital or acquired bleeding disorder.\n* Use of anticoagulation medication during the study, i.e. aspirin, Coumadin, Plavix, or medications similar in class to these medications will exclude the patient from participation.\n* Inability to provide informed consent (patients under guardianship).\n* Known hypersensitivity to local anesthetics\n* History of cardiac disease; such as current impaired cardiovascular function, past history of myocardial infarction, congenital heart disease, current cardiac symptoms, i.e. angina, shortness of breath, or chest pain as determined by history or review of the medical record.\n* History of complex pulmonary disease; such as uncontrolled asthma, COPD, or interstitial lung disease as determined by history or review of the medical record.\n\nImpaired renal function as documented in the medical record in the last 3 months with a serum creatinine greater than 1.2 mg\u002FdL or glomerular filtration rate \\\u003C 60 mL\u002Fmin\u002FBSA as determined by history or review of the medical record.\n\n\\- History of or current hepatic disease as documented by liver function test abnormality in the last 3 months as determined by history or review of the medical record.",true,{"count":82,"type":20},60,[84],"PHASE4","The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.",[26],"2025-09-10",{"date":89,"type":33},"2025-09-12",{"date":91,"type":33},"2022-05-04",{"date":93,"type":20},"2026-09",{"name":95,"class":40},"Mayo Clinic"]