[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nasogastric-tube\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nasogastric-tube":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,81],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100580802","ai-assisted-chest-x-ray-for-misplaced-endotracheal-and-nasogastric-tubes-and-pneumothorax-in-emergency-and-critical-care-settings-100580802",false,"NCT06842043","AI-Assisted Chest X-Ray for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings","Clinical Effectiveness and Cost-Effectiveness of Real-Time Chest X-Ray Computer-Aided Detection System for Misplaced Endotracheal and Nasogastric Tubes and Pneumothorax in Emergency and Critical Care Settings","Inclusion Criteria for units:\n\n* Emergency critical care or intensive care units.\n* The units included the patients requiring chest X-rays due to endotracheal intubation, nasogastric tube insertion, or ventilator use with a risk of pneumothorax.\n\nExclusion Criteria for units:\n\n* The unit supervisor doesn't agree to participate in the trial.\n* The unit is unable to implement the AI-assisted system (e.g., no data connection or system support).\n\nInclusion Criteria for Patients:\n\n● Patients who are adults and require chest X-ray due to one of the following conditions: endotracheal intubation, nasogastric intubation, or the use of a ventilator with the potential to cause pneumothorax.\n\nExclusion Criteria for Patients: Patients in isolation wards or pediatric\n\n* Patients in isolation wards.\n* Patients in Infant Intensive Care Unit","ALL","18 Years",{"count":19,"type":20},10900,"ESTIMATED","INTERVENTIONAL",[23],"NA","Background Advancements in artificial intelligence (AI) have driven significant breakthroughs in computer-aided detection (CAD) for chest X-ray imaging. National Taiwan University Hospital (NTUH) research team previously developed an AI-based emergency Capstone CXR system (MOST 111-2634-F-002-015-, Capstone project), which led to the creation of a chest X-ray module. This chest X-ray module has an established model supported by extensive research and is ready for direct application in clinical trials without requiring additional model training. This study will utilize three submodules of the system: detection of misplaced endotracheal tubes, detection of misplaced nasogastric tubes, and identification of pneumothorax.\n\nObjective This study aims to apply a real-time chest X-ray CAD system in emergency and critical care settings to evaluate its clinical and economic benefits without requiring additional chest X-ray examinations or altering standard care and procedures. The study will evaluate the CAD system's impact on mortality reduction, post-intubation complications, hospital stay duration, workload, and interpretation time, alongside a cost-effectiveness comparison with standard care.\n\nMethods This study adopts a pilot trial and cluster randomized controlled trial design, with random assignment conducted at the ward level. In the intervention group, units are granted access to AI diagnostic results, while the control group continues standard care practices. Consent will be obtained from attending physicians, residents, and advanced practice nurses in each participating ward. Once consent is secured, these healthcare providers in the intervention group will be authorized to use the CAD system. Intervention units will have access to AI-generated interpretations, whereas control units will maintain routine medical procedures without access to the AI diagnostic outputs.\n\nResults The study was funded in September 2024. Data collection is expected to last from January 2025 to December 2027.\n\nConclusions This study anticipates that the real-time chest X-ray CAD system will automate the identification and detection of misplaced endotracheal and nasogastric tubes on chest X-rays, as well as assist clinicians in diagnosing pneumothorax. By reducing the workload of physicians, the system is expected to shorten the time required to detect tube misplacement and pneumothorax, decrease patient mortality and hospital stays, and ultimately lower healthcare costs.",[26,27,28],"Endotracheal Tube","Nasogastric Tube","Pneumothorax",[30,31,32,33,34,35,36],"Computer-aided detection system","Artificial intelligence","Pneumothorax diagnosis","Endotracheal tube","Nasogastric tube","Clinical effectiveness","Cost effectiveness","NOT_YET_RECRUITING","2026-03-15",{"date":40,"type":41},"2026-03-17","ACTUAL",{"date":43,"type":20},"2026-04-01",{"date":45,"type":20},"2027-12-31",{"name":47,"class":48},"National Taiwan University Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":21,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":49},"100574933","effects-of-intermittent-feeding-methods-with-nasogastric-and-orogastric-tubes-in-preterm-infants-100574933","NCT06765720","Effects of Intermittent Feeding Methods With Nasogastric and Orogastric Tubes in Preterm Infants","The Comparison of the Effects of Intermittent Feeding Methods With Nasogastric and Orogastric Tubes on Growth, Nutrition, and Physiological Parameters in Preterm Infants: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Preterm infants with a gestational age of ≥30 weeks at birth, determined according to the mother's last menstrual period, and appropriate for gestational age,\n* Postmenstrual age of ≥30 weeks at the time of inclusion in the study,\n* Recommended for enteral feeding by a neonatologist,\n* Infants starting enteral feeding for the first time and fed at three-hour intervals using gravity-assisted nasogastric or orogastric tubes,\n* Infants who have not undergone oral feeding trials,\n* Infants who have not received any oral motor interventions,\n* Infants whose parents have given consent for inclusion in the study and signed an informed consent form after being provided with detailed information.\n\nExclusion Criteria:\n\n* Infants receiving mechanical ventilation support during the study,\n* Infants with an umbilical catheter,\n* Infants who received intubation, CPAP, or nasal prong oxygen support for more than 14 days before inclusion in the study,\n* Infants with craniofacial anomalies such as cleft palate, cleft lip, or facial muscle paralysis,\n* Infants with any gastrointestinal, neurological, or chromosomal disease (e.g., necrotizing enterocolitis, grade III and IV intracranial hemorrhage, periventricular leukomalacia, hydrocephalus, Down syndrome, and other diseases),\n* Infants with severe bronchopulmonary dysplasia according to the criteria of Jobe and Bancalari (2001) or requiring surgical treatment for patent ductus arteriosus.",true,"30 Weeks","36 Weeks",{"count":61,"type":20},60,[23],"The study is a randomized controlled, prospective, double-blind trial planned to compare the effects of intermittent feeding methods using nasogastric and orogastric tubes on the growth, nutrition, and physiological parameters of preterm infants.\n\nThe population of the study will consist of preterm infants admitted to the Neonatal Intensive Care Unit of a public hospital in Istanbul between February and December 2025. The sample will include 60 preterm infants who meet the research criteria and whose parents agree to participate in the study.\n\nThrough randomization, preterm infants will be assigned to either the nasogastric tube group (experimental) or the orogastric tube group (control) from their first enteral feeding until the transition to full oral feeding is completed.\n\nData for preterm infants in both groups will be collected using the \"Preterm Infant Information Form, Early Feeding Skills Assessment Tool, and Nutrition Monitoring Form,\" which were developed by the researchers based on literature information and expert opinions. These data will encompass growth, nutrition, and physiological parameters before, during, and after feeding throughout the study.\n\nHypotheses of the Study\n\nH0: There is no significant difference in the effects of intermittent feeding methods using nasogastric and orogastric tubes on growth, feeding complications, and physiological parameters in preterm infants.\n\nH1: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of growth parameters (daily weight gain in grams, time to regain birth weight, time to transition to full enteral feeding, time to transition to full oral feeding, and Early Feeding Skills Assessment Tool score).\n\nH1(1): Preterm infants fed with a nasogastric tube have greater daily weight gain (grams) compared to those fed with an orogastric tube.\n\nH1(2): The time to regain birth weight (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(3): The time to transition to full enteral feeding (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(4): The time to transition to full oral feeding (days) in preterm infants fed with a nasogastric tube is shorter compared to those fed with an orogastric tube.\n\nH1(5): The Early Feeding Skills Assessment Tool score of preterm infants fed with a nasogastric tube is higher compared to those fed with an orogastric tube.\n\nH2: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of feeding complications (tube replacement, mucosal trauma, and feeding intolerance).\n\nH2(1): The frequency of tube replacement in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH2(2): The incidence of mucosal trauma in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH2(3): The incidence of feeding intolerance in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH3: There is a significant difference between intermittent feeding methods using nasogastric and orogastric tubes in preterm infants in terms of physiological parameters (oxygen saturation, heart rate, and apnea).\n\nH3(1): The oxygen saturation levels during and after feeding in preterm infants fed with a nasogastric tube are higher compared to those fed with an orogastric tube.\n\nH3(2): The heart rate during and after feeding in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.\n\nH3(3): The incidence of apnea in preterm infants fed with a nasogastric tube is lower compared to those fed with an orogastric tube.",[27,65],"Orogastric Tube",[67,68,69,70,71],"intermittent feeding","enteral feeding","nasogastric tube","orogastric tube","preterm","2025-01-03",{"date":74,"type":41},"2025-01-09",{"date":76,"type":20},"2025-02-01",{"date":78,"type":20},"2025-12-01",{"name":80,"class":48},"İstanbul Yeni Yüzyıl Üniversitesi",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":98,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":49},"100502100","diagnostic-accuracy-of-capnography-in-nasogastric-tube-placement-100502100","NCT05817864","Diagnostic Accuracy of Capnography in Nasogastric Tube Placement","Diagnostic Accuracy of Using Capnography in Verification of Nasogastric Tube Placement in Hospital Settings","Inclusion Criteria:\n\n* 18 years old or above;\n* Admitted to the general medical and geriatric wards, ICUs, or subacute\u002Frehabilitation\u002Finfirmary wards in subacute\u002Fconvalescent\u002Fextended care hospitals or visiting AEDs in acute hospitals;\n* Requiring the insertion of an nasogastric tube into the stomach for assessment, nutritional support and medication administration during the study period.\n\nExclusion Criteria:\n\n* Participants receiving life-saving intervention at the time of recruitment.",{"count":89,"type":20},390,"OBSERVATIONAL","A prospective observational diagnostic study will be conducted to assess the sensitivity and specificity of using capnography in detecting the correct placement of nasogastric tubes using the reference standards of radiography and measurement of aspirates for pH value.",[93,27,94],"Capnography","Diagnostic Accuracy",[93,96,97],"Intubation, gastrointestinal","Diagnostic accuracy","RECRUITING","2024-09-02",{"date":101,"type":41},"2024-09-05",{"date":103,"type":41},"2023-07-01",{"date":105,"type":20},"2025-12",{"name":107,"class":48},"Chinese University of Hong Kong"]