[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nature-human\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nature-human":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,90],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100562918","the-effect-of-nature-and-game-based-activities-on-older-people-100562918",false,"NCT06609408","The Effect of Nature and Game Based Activities on Older People","The Effect of Nature and Game Based Activities on Happiness, Spiritual Well-Being, Frailty and Cognitive Status of Older People in Nursing Home","Inclusion Criteria:\n\n* Older people who have been in a nursing home for at least 6 months,\n* Older people aged 65 years and over,\n* Older people with a Mini Mental State score of 24 and above,\n* Older people who are open to communication and co-operation will be included in the study.\n\nExclusion Criteria:\n\n* Older people with physical problems that may prevent them from participating in nature and game based activities (such as stroke, Parkinson\\'s),\n* Older people with visual and hearing loss that may pose an obstacle to nature and game based activities,\n* Older people with mental problems (such as dementia) that would prevent participation in nature and game based activities were excluded from the study.","ALL","65 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is determine the effect of nature and game based activities on happiness, spiritual well-being, frailty and cognitive status of older people in nursing home.\n\nHypotheses of the Research H0: Nature and game-based activities don't affect the happiness, spiritual well-being, cognitive function and frailty of older people in nursing home.\n\nH1a: Happiness levels of older people in nursing home will be an increase after nature and game-based activities.\n\nH1b: Spiritual well-being levels of older people in nursing home will be an increase after nature and game-based activities.\n\nH1c: Cognitive function levels of older people in nursing home will be an increase after nature and game-based activities.\n\nH1d: Frailty status of older people in nursing home will be a decrease after nature and game-based activities.",[26,27,28,29,30,31,32],"Nature, Human","Older People","Nursing Home","Happiness","Spiritual Well-being","Frailty","Cognitive Ability, General",[34,27,28,29,35,31,36],"Nature","Spiritual Well-Being","Cognition","NOT_YET_RECRUITING","2025-06-11",{"date":40,"type":41},"2025-06-12","ACTUAL",{"date":43,"type":20},"2025-07-01",{"date":45,"type":20},"2026-05-01",{"name":47,"class":48},"Ondokuz Mayıs University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":21,"phases":63,"briefSummary":64,"conditions":65,"keywords":72,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":89},"100546126","nationwide-research-on-the-rewilding-of-kindergarten-yards-100546126","NCT06390878","Nationwide Research on the Rewilding of Kindergarten Yards","Nationwide Research on the Rewilding of Kindergarten Yards - Vahvistu","Vahvistu","Inclusion Criteria:\n\n* Attendance in kindergarten\n\nExclusion Criteria:\n\n* Use of antibiotics in the year before sampling",true,"1 Year","5 Years",{"count":62,"type":20},320,[23],"Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity in cities that is associated with altered commensal microbiota and a rising burden of immunological disorders among urban children.\n\nThe investigators will estimate how rewilding of kindergarten yards affects commensal microbiome, prevalence of allergies, asthma, atopic dermatitis and infections, cortisol levels, cognitive skills and plasma cytokine levels of children.\n\nOur specific aims are:\n\nTo assess if rewilding diversifies health-associated skin, saliva and gut microbiota and reduces infectious diseases and atopic or allergic symptoms.\n\nAssess whether the rewilding has positive effects on cognitive skills. Assess whether the rewilding changes cortisol and plasma cytokine levels. The investigators will recruit altogether 320 (160 per treatment) study subjects aged between 1-5 to questionnaire study (Task 2), from which 120 study subjects will be analyzed more detailed using microbiological and blood samples (Task 1).",[66,67,68,69,70,71,26],"Microbial Colonization","Atopic Dermatitis","Asthma in Children","Allergy","Cognitive Change","Respiratory Infection",[73,74,75,76,77],"Commensal microbiome","Atopy","Planetary health","Biodiversity","Cognitive skills","RECRUITING","2024-06-20",{"date":81,"type":41},"2024-06-24",{"date":83,"type":41},"2024-05-15",{"date":85,"type":20},"2027-08-30",{"name":87,"class":88},"Natural Resources Institute Finland","OTHER_GOV",2,{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":96,"eligibilityCriteria":97,"healthyVolunteers":58,"sex":16,"minAge":98,"maxAge":60,"enrollmentInfo":99,"targetDuration":4,"studyType":21,"phases":101,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":89},"100546112","sand-play---the-effect-of-biodiversity-exposure-on-atopic-dermatitis-100546112","NCT06390696","Sand Play - the Effect of Biodiversity Exposure on Atopic Dermatitis","Biodiversity Interventions for Well-being - the Effect of Biodiversity Exposure on Atopic Dermatitis","BIWE","Inclusion Criteria:\n\n* Eczema Area and Severity Index ≥ 2\n\nExclusion Criteria:\n\n* Eczema Area and Severity Index \\\u003C 2\n* Immune deficiencies, i.e., antibody deficiency\n* Immunosuppressive systematic medications\n* A disease affecting immune response (e.g., colitis ulcerosa, rheumatoid arthritis, Crohn's disease, diabetes)\n* Cancer diagnosis\n* Topical medication for the treatment of atopic dermatitis during the trial\n* Disability affecting the immune response (e.g. Down's syndrome)\n* Non-participation in the national vaccine program\n* Participation in another intervention or follow-up study","2 Years",{"count":100,"type":20},80,[23],"The prevalence of atopic dermatitis has increased along with urbanization and biodiversity loss. According to biodiversity hypothesis, the main reason is urban lifestyle and reduced contact to microbial diversity. Previous studies indicate association between atopic dermatitis and exposure to natural microbes in childhood.\n\nSand Play - the Effect of Biodiversity Exposure on Atopic Dermatitis will investigate whether the exposure to microbial diversity in sandbox reduces the symptoms of atopic dermatitis, alters commensal microbiota and modifies immune regulation in children.",[67,26,66,104],"Immune System and Related Disorders",[74,76,106,107],"Commensal microbiota","Microbial exposure","2024-04-25",{"date":110,"type":41},"2024-04-30",{"date":112,"type":41},"2023-05-26",{"date":114,"type":20},"2027-09-30",{"name":87,"class":88}]