[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neglect-hemispatial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neglect-hemispatial":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,43,70,96,120,149,171],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100629857","motor-imaging-neglect-and-upper-extremity-function-in-stroke-100629857",false,"NCT07480122","Motor Imaging, Neglect, and Upper Extremity Function in Stroke","Investigation of the Relationship Between Motor Imagery Skill and Neglect Level, Upper Extremity Motor Function, Activities of Daily Living, and Quality of Life in Individuals After Stroke","Inclusion Criteria:\n\n* Individuals who have experienced hemiplegia after an ischemic stroke,\n* who actively use their right extremity according to the Edinburgh Hand Preference Questionnaire,\n* who have right hemisphere involvement,\n* who are 18 years of age or older,\n* who have been diagnosed with a stroke at least 1 and at most 6 months ago,\n* who have middle cerebral artery involvement,\n* who have a Standardized Mini Mental Test score of 24 or higher,\n* who are Stage 2b or higher according to Eggers staging,\n* who can actively control their hand, wrist, and fingers and perform the release reflex,\n* who wish to participate in the study voluntarily, and\n* who have given their informed consent will be included in the research.\n\nExclusion Criteria:\n\n* Individuals with major neurological, orthopedic, or rheumatological disorders affecting upper extremity function other than stroke (Polyneuropathy, Parkinson's Disease, Multiple Sclerosis, Rheumatoid Arthritis, etc.),\n* Individuals with upper extremity amputation,\n* Individuals with uncontrolled arrhythmia, uncontrolled hypertension, or unstable cardiac conditions,\n* Individuals with active malignancy and receiving related chemo\u002Fradiotherapy,\n* Individuals unable to cooperate due to aphasia or cognitive impairment,\n* Individuals with visual and hearing problems,\n* Individuals with communication problems that would hinder the evaluation and\u002For implementation of the treatment program,\n* Individuals who are unable to undergo mental assessment, complete the scales, or are illiterate will be excluded from the study.","ALL","30 Years","80 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","This study aims to investigate the relationship between motor imagery skills and neglect level, upper extremity motor function, activities of daily living, quality of life, lateralization performance, and mental timer performance in individuals with stroke. Individuals with stroke who meet the inclusion criteria and voluntarily agree to participate will be evaluated. Demographic and clinical information of the participants will be recorded on an assessment form prepared by the researcher. Upper extremity motor functions will be assessed using the Fugl-Meyer Upper Extremity Motor Assessment Scale and the Wolf Motor Function Test; activities of daily living will be assessed using the Modified Barthel Index; and quality of life will be assessed using the Stroke-Specific Quality of Life Scale. Motor imagery skills will be measured using the Kinesthetic and Visual Imagery Questionnaire and a mental timer task; upper extremity lateralization performance will be assessed using the Recognise™ application. Neglect level will be assessed using the Catherine Bergego Scale, the Line Splitting Test, and the Star Erase Test. The data obtained will be statistically analyzed to examine the relationships between motor imagery skills and other clinical variables.",[25,26,27,28,29,30],"Stroke","Neglect, Hemispatial","Motor ımargery","Upper Extremity Function","Daily Life Activity","Quality of Life","NOT_YET_RECRUITING","2026-05-21",{"date":34,"type":35},"2026-05-22","ACTUAL",{"date":37,"type":21},"2026-05-25",{"date":39,"type":21},"2026-08-15",{"name":41,"class":42},"Inonu University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":69},"100618459","strategy-training-for-optimizing-attention-for-individuals-with-spatial-neglect-100618459","NCT07331896","Strategy Training for Optimizing Attention for Individuals With Spatial Neglect","Examining Strategy Training for Optimizing Attention in Rehabilitation for Community-Dwelling Individuals With Spatial Neglect","SOAR","Inclusion Criteria:\n\n* had a stroke\n* presence of neglect as determined by score of \\\u003C18 or 2 or more collisions on the Virtual Reality Lateralized Attention Test (VRLAT); score below established cutoff for neglect on one of the six subtests of the Behavioral Inattention Test (BIT); OR reported signs\u002Fsymptoms of neglect\n* ≥18 years old\n* lives within 30 miles of the University of Pittsburgh in a community dwelling.\n\nExclusion Criteria:\n\n* Boston Diagnostic Aphasia Examination (BDAE) Severity Scale score of 0\n* dementia per medical record\n* active major depressive disorder per medical record\n* not willing to be videotaped\n* subject is currently receiving rehabilitation therapy as part of their usual care","18 Years",{"count":53,"type":21},45,"INTERVENTIONAL",[56],"NA","It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect). Individuals with neglect have difficulty paying attention to one side of their body or one side of the environment and therefore experience difficulty performing daily activities. There are a lack of effective treatments for neglect and new interventions are needed to help reduce disability for these individuals. Metacognitive strategy training (strategy training) is an intervention that has the potential to reduce neglect-related disability and improve individuals' attention and awareness of their neglect. This study seeks to examine the effects of strategy training on neglect, self-awareness, and disability, specifically for individuals who are living in the community after their stroke.",[25,26],"RECRUITING","2026-05-08",{"date":62,"type":35},"2026-05-12",{"date":64,"type":35},"2026-04-06",{"date":66,"type":21},"2029-01",{"name":68,"class":42},"University of Pittsburgh",1,{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":54,"phases":80,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":69},"100610458","mixed-reality-visual-attention-task-for-neglect-diagnosis-and-rehabilitation-100610458","NCT07227844","Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation","Pilot Study of a Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation","Neglex01","Inclusion Criteria:\n\n* The study will involve patients over the age of 18 who have been diagnosed with a neurological injury that includes: ischemic stroke, hemorrhagic stroke, tumor, or trauma.\n* Neurological injury that localizes to only one side of the brain\n* At least one hand that retains dexterity enough to use a controller to extinguish the visual stimulus.\n* Cognitive ability to understand simple instructions on how to use the device\n* Visual fields intact\n\nExclusion Criteria:\n\n* Bilateral symptomatic injury\n* Inability to consent or to comply with study\n* Blindness or severe visual deficits other than neglect",{"count":79,"type":21},5,[56],"Neglect, a common and disabling neurological deficit post-CNS injury, profoundly hinders recovery and escalates healthcare costs. Current diagnostic tools are often insensitive or impractical, and while therapies exist, a significant research gap remains. Traditional methods, including standardized scales and paper-pencil tests, lack precision; even advanced video oculography is limited by cost and accessibility. Rehabilitative approaches like visual scanning and prism adaptation offer some benefit, but more effective solutions are needed. This project utilizes a non-invasive neuromodulatory training approach via a mixed-reality visual attention task delivered through a virtual reality headset. This system aims to improve both neglect diagnosis and personalized therapeutic intervention. The study will assess the headset's safety and practicality, its capacity to detect and lateralize neglect, and its long-term effect on improving attention to the neglected field. By measuring reaction times to visual stimuli within the VR environment, the research seeks to develop a more accessible and impactful tool for both assessing and treating neglect, potentially enabling self-directed therapy and enhancing patient outcomes.",[83,26,84],"Neglect, Sensory","Neglect, Hemisensory",[86],"neglect","2025-11-11",{"date":89,"type":35},"2025-11-13",{"date":91,"type":21},"2025-12-31",{"date":93,"type":21},"2026-12-31",{"name":95,"class":42},"Markey Olson",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":54,"phases":105,"briefSummary":106,"conditions":107,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":69},"100553218","implementation-of-ivs3-for-upper-limb-motor-recovery-100553218","NCT06483230","Implementation of IVS3 for Upper Limb Motor Recovery","A Pilot Study on Tolerance and Ease of Implementation of Intensive Visual Stimulation (IVS3) in Daily Practice for Upper Limb Motor Recovery in Outpatient Rehab Center","Inclusion Criteria:\n\n1. Age ≥ 18 years old\n2. English speaking\n3. History of ischemic or hemorrhagic stroke ≥ 6 months prior to study enrolment\n4. FMA-UE: 20 \\\u003C x \\\u003C 50 (moderate impairments)\n5. With or without hemi spatial neglect\n\nExclusion Criteria:\n\n1. Spasticity or increased tone with MAS ≥3 in the upper extremity\n2. Unable to communicate effectively or provide informed consent\n3. Significant visual impairments\n4. Concurrent occupational therapy being received outside of the study\n5. Pregnant or incarcerated individuals",{"count":104,"type":21},25,[56],"This study measures participant satisfaction and upper extremity function in outpatients with chronic stroke when exposed to the IVS3 device. Investigators hypothesize that treatment with the IVS3 device will be feasible and tolerable for use in the outpatient setting.",[26,108,109,110],"Stroke, Cardiovascular","Mirror Movement","Motor Activity","2025-10-27",{"date":113,"type":35},"2025-10-29",{"date":115,"type":35},"2024-10-02",{"date":117,"type":21},"2027-06",{"name":119,"class":42},"Weill Medical College of Cornell University",{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":16,"minAge":128,"maxAge":129,"enrollmentInfo":130,"targetDuration":4,"studyType":54,"phases":132,"briefSummary":133,"conditions":134,"keywords":136,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":4},"100427401","improving-awareness-for-spatial-neglect-with-tdcs-100427401","NCT04845529","Improving Awareness for Spatial Neglect With tDCS","Improving Awareness in Right-brain-damaged Patients With Unilateral Spatial Neglect Using Transcranial Direct Current Stimulation (tDCS)","ANOSO","Inclusion Criteria:\n\n* First stroke affecting the right-hemisphere\n* Presence of USN, as assessed by a standard neuropsychological evaluation\n* Structural images of the brain lesion available (magnetic resonance or tomographic scans)\n* Criteria for electrical brain stimulation\n* Good (or corrected) visual acuity\n* High proficiency in French\n* Right-handed\n\nExclusion Criteria:\n\n* Presence of general cognitive deficits and\u002For suspicious of possible cognitive deficits\n* Presence of difficulty in task's comprehension\n* Impossibility to sustain a research session of at least 45minutes (e.g., attentional lability)\n* Precedent additional neurological disorder and\u002For current or precedent psychiatric disease\n* Presence of one or more exclusion criteria for the electrical brain stimulation 18, as following:\n\nPresence (or suspected presence) of metal in the brain or skull or body (except titanium) (e.g. splinters, fragments, clips, etc.) Presence of cochlear implants, implanted neuro-stimulator (e.g., DBS, epidural\u002Fsubdural, VNS), cardiac pacemaker, medication infusion device, spinal or ventricular derivations Presence of epilepsy (participant and\u002For the close family) and\u002For precedent epileptic seizures (participant) Presence of a fainting spell or syncope, due to neurological diseases (not consider syncope during blood sampling or after being in a warm environment or after emotionally stressful events) Presence of a severe (i.e., followed by loss of consciousness) head trauma Presence of hearing problems or ringing in your ears (e.g. tinnitus) Current treatment under psychoactive (e.g. antidepressants, tranquilizers) or antiepileptic medications Chronic headache For women: you are pregnant or there is any chance that you might be.","20 Years","85 Years",{"count":131,"type":21},12,[56],"Brain-damaged patients can show severe neurological and cognitive deficits, and yet often remain strikingly unaware of these symptoms: this condition is called anosognosia. The aim of this study is to improve awareness in right-brain-damaged patients with Unilateral Spatial Neglect (USN) following stroke using transcranial direct current stimulation (tDCS). tDCS is a neuromodulatory technique that delivers low-intensity current to the brain facilitating (anodal tDCS) or inhibiting (cathodal tDCS) spontaneous neuronal activity. tDCS does not induce activity in resting neuronal networks, but modulates spontaneous neuronal activity: consequently, the amount and direction of effects critically depend on the previous state of the neural structures.\n\nWe will test USN patients showing anosognosia for neglect symptoms. Different brain areas will be stimulated, to target explicit and implicit components of anosognosia, including parietal and frontal brain regions.",[25,135,26],"Anosognosia",[137,138,139],"Brain modulation","Recovery","Implicit and explicit anosognosia","2025-05-23",{"date":142,"type":35},"2025-05-30",{"date":144,"type":21},"2026-12",{"date":146,"type":21},"2027-01",{"name":148,"class":42},"University of Geneva, Switzerland",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":156,"targetDuration":4,"studyType":54,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":69},"100592902","assessment-and-treat-neglect-patients-with-a-vr-application-100592902","NCT06999473","Assessment and Treat Neglect Patients With a VR Application","Assess and Treat Visuospatial Neglect in Central Neurological Conditions Via an Innovative Virtual Reality Software","Inclusion Criteria:\n\n1. Age 18 years or older\n2. Able to provide informed consent\n3. have had a hemispheric stroke\n\nExclusion Criteria:\n\n1. Have a severe comorbid psychiatric (E.g. psychotic symptoms) disorder\n2. Have a premorbid neurodegenerative disease (E.g. Alzheimer's dementia, vascular dementia)\n3. Have severe written language comprehension deficits\n4. Have a medical implant, such as a cochlear implant or a pacemaker\n5. Have a severe visual impairment that cannot be corrected by wearing glasses while training\n6. Have a history of epileptic seizures The following exclusion criteria do not apply to the Non-VSN stroke group.\n7. Do not show signs of a spatial asymmetry in performance on a battery of screening tasks\n8. Having visual field deficits or lesions in the occipital lobe",{"count":157,"type":21},30,[56],"The objective of this project is to investigate the effectiveness of neglect training in our self-developed VR application \"SpatialSense\". The investigators aim to reach the following goals:\n\ni. Compare conventional neglect therapy for neglect training with SpatialSense to evaluate the impacts on neglect recovery to see whether the VR therapy improves the clinical outcomes, such as balance recovery, perception of verticality, quality of life, independence in daily activities, and cognitive impairment, after rehabilitation training.\n\nii. Analyze and compare the search strategies employed by stroke patients with VSN and those without VSN during the execution of the search task with SpatialSense to summarize typical visual scanning strategies for facilitation, rehabilitation training, and improving the transfer effect in daily activities.\n\nThe experimental group will receive both conventional OT and PT treatment, but 3 days a week, half an hour of conventional treatment will be replaced by treatment with SpatialSense software. The control group will receive their regular dose-matched conventional OT and PT sessions without interference. The experimental group will receive SpatialSense training 3 times a week for a consecutive 4 weeks (12 sessions in total of 30 minutes).",[26,25,161],"Virtual Reality Therapy","2025-05-22",{"date":164,"type":35},"2025-05-31",{"date":166,"type":21},"2025-06-01",{"date":168,"type":21},"2027-07-01",{"name":170,"class":42},"Universiteit Antwerpen",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":177,"eligibilityCriteria":178,"healthyVolunteers":11,"sex":16,"minAge":128,"maxAge":18,"enrollmentInfo":179,"targetDuration":4,"studyType":54,"phases":180,"briefSummary":181,"conditions":182,"keywords":185,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":69},"100584525","robotic-rehabilitation-scenario-for-patients-with-neglect-100584525","NCT06890481","Robotic rEhabilitation sCenario fOr patieNts With NeglECT","Collaborative Development of a Virtual Reality Scenario, Integrated Into a Robotic Upper Limb Rehabilitation Device, for the Treatment of Unilateral Spatial Negligence (NSU) Through Mutisensory Stimulation: Feasibility and Usability Pilot Study","RECONNECT","Inclusion Criteria:\n\n* Presence of a diagnosis of right hemispheric stroke\n* Presence of a diagnosis of hemi-inattention (Apple test)\n* Presence of left hemiplegia (Fugl-Meyer Assessment Upper Limb ≤58)\n* Adjusted Montreal Cognitive Assessment \\\u003C20\n* Written informed consent\n\nExclusion Criteria:\n\n* Presence of cognitive decline prior to the event\n* Presence of previous stroke events\n* Presence of osteoarticular rigidity (e.g., ankylosis, functional limitations with traumatic or degenerative origin) or spasticity in the affected upper limb (Modified Ashworth Scale ≥3 on shoulder, elbow, or wrist)\n* Inability to maintain a sitting position\n* Presence of severe visual disabilities\n* Recent injection of botulinum toxin in the upper limb or planned injection of botulinum toxin during the study period\n* Orthopaedic, neurological, or psychiatric disorders that could interfere with the study procedures and motor or cognitive assessments\n* Unstable fractures of the upper limb\n* Severe osteoporosis\n* Skin lesions on the upper limb",{"count":131,"type":21},[56],"The goal of this pilot clinical trial is to develop an integrated motor and cognitive rehabilitation program and evaluate the usability and acceptability of a new virtual reality scenario designed for the MOTORE device. This study will focus on the rehabilitation of the upper limbs in post-stroke patients with plegia and left-sided hemi-inattention. The main questions it aims to answer are:\n\n* The evaluation of the usability and acceptability of the newly developed scenario\n* The evaluation of the effects of the new scenario on patients' hemi-inattention\n* The evaluation of changes in upper limb functional parameters\n\nParticipants will undergo a total of 13 rehabilitation sessions, each lasting 45 minutes, using the new scenario, including an initial and final assessment.",[25,183,184,26],"Ischemic Stroke","Haemorrhagic Stroke",[186,187,188,189,190,86,191],"stroke","robotics","end-effector","upper-limbs","rehabilitation","usability","2025-03-31",{"date":194,"type":35},"2025-04-03",{"date":196,"type":21},"2025-04-01",{"date":198,"type":21},"2026-04-01",{"name":200,"class":42},"Fondazione Don Carlo Gnocchi Onlus"]