[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nemaline-myopathy-5\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nemaline-myopathy-5":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100544886","witnness---tnnt1-myopathy-natural-history-study-100544886",false,"NCT06374719","WiTNNess - TNNT1 Myopathy Natural History Study","WiTNNess: An International Natural History Study of Autosomal Recessive TNNT1 Myopathy","WiTNNess","Inclusion Criteria:\n\n* Diagnosed with biallelic pathogenic variants of TNNT1\n* Infantile-onset or childhood-onset proximal weakness without confounding medical conditions that could effect muscle health.\n\nExclusion Criteria:\n\n* Another known or suspected medical condition (genetic or acquired) that could potentially alter the natural disease course or otherwise interfere with completion of study procedures.","ALL",{"count":19,"type":20},40,"ESTIMATED","3 Years","OBSERVATIONAL","WiTNNess is designed to accurately document the natural course and variation of muscle disease caused by pathogenic changes of the TNNT1 gene. The primary aim of the study is to specify meaningful outcome measures for future clinical trials. WiTNNess is open to children and adults worldwide. Participants can choose to include their information once (cross-sectional cohort) or every few months (prospective cohort).",[25,26,27,28,29,30,31,32,33,34,35,36],"TNNT1-associated Myopathy","Infantile-onset Nemaline Rod Myopathy","Myopathies, Nemaline","Myopathy","Myopathy, Rod","Myopathy; Hereditary","Amish Nemaline Myopathy","Nemaline Myopathy 5","NEM5","Genetic Muscle Disease","Recessive Hereditary Disorder (Autosomal)","ANM","RECRUITING","2026-06-19",{"date":40,"type":41},"2026-06-23","ACTUAL",{"date":43,"type":41},"2018-09-23",{"date":45,"type":20},"2027-06-01",{"name":47,"class":48},"Clinic for Special Children","OTHER"]