[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neobladder-diversion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neobladder-diversion":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100530700","early-phase-1-prophylactic-antibiotics-in-cystectomy-with-diversion-100530700",false,"NCT06190197","Prophylactic Antibiotics in Cystectomy With Diversion","Prophylactic Antibiotics in Radical Cystectomy With Urinary Diversion","Inclusion Criteria:\n\n* Presence of muscle invasive bladder cancer and planning to undergo radical cystectomy with either ileal conduit or neobladder diversion.\n* 18 years of age or older\n\nExclusion Criteria:\n\n* Currently receiving antimicrobials for active infection\n* Poor renal function with GFR \\\u003C 30 ml\u002Fmin\n* Allergy to nitrofurantoin and unable to take an alternative antibiotic (cephalexin, trimethoprim-sulfamethoxazole, or ciprofloxacin)\n* Pregnancy\n* Unable to provide Informed consent\n* Prior pelvic radiation","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.",[26,27,28,29],"Muscle-Invasive Bladder Carcinoma","Radical Cystectomy","Ileal Conduit","Neobladder Diversion","RECRUITING","2025-11-13",{"date":33,"type":34},"2025-11-17","ACTUAL",{"date":36,"type":34},"2024-05-13",{"date":38,"type":20},"2027-10-15",{"name":40,"class":41},"University of Minnesota","OTHER"]