[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neonates\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neonates":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,60,88,118],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100632476","improving-artificial-intelligence-derived-algorithms-for-estimating-length-and-weight-in-neonates-and-infants-up-to-6-months-of-age-nest-100632476",false,"NCT07514182","Improving Artificial Intelligence-derived Algorithms for Estimating Length and Weight in NEonateS and infanTs up to 6 Months of Age (NEST)","Improving Artificial Intelligence-derived Algorithms for Estimating Length and Weight in NEonateS and infanTs up to 6 Months of Age","NEST","Inclusion Criteria:\n\n1. Infants up from birth up to 6 months of postnatal age (including neonates) who have been admitted to the NICU or SCN at the time of screening\n2. Parent(s) should be able to comprehend the content of the study and be willing for their child to undergo video and photo recording, and to allow access to their blood sampling results (haemoglobin) taken as part of standard clinical practice\n3. Written consent from parents and\u002For legally acceptable representative\n\nExclusion Criteria:\n\n1. Infants who were born with gestational age of less than 28 weeks of gestational age\n2. Infants who are intubated (i.e., endotracheal, nasotracheal intubation) at the time of screening\n3. The investigator considers for any reason that the participant would not be suitable for the study\n4. The participant has an existing medical condition that would prevent standardised measurement of length and\u002For head circumference e.g. structural abnormality of the lower limbs, orthopaedic conditions, hydrocephalus\n5. Employees and\u002For children\u002Ffamily members or relatives of employees of Danone Global Research \\& Innovation Center, Danone Asia Pacific Holdings Pte Ltd, or the participating site","ALL","0 Days","6 Months",{"count":21,"type":22},60,"ESTIMATED","2 Weeks","OBSERVATIONAL","The NEST study is a prospective, observational research study designed to collect clinical measurements and image data to develop and evaluate artificial intelligence (AI)-derived algorithms for estimating anthropometric parameters in neonates and young infants. The study focuses on infants from birth up to 6 months of age and aims to assess the accuracy of AI-based estimations of length, weight, and head circumference using photographs and\u002For video recordings captured during routine clinical care. These AI-derived measurements will be compared against standard clinical measurements obtained by trained healthcare professionals in neonatal and infant care settings.",[27,28,29],"Growth","Neonates","AI (Artificial Intelligence)",[28,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46],"Infants","Neonatal Growth","Infant Growth assessment","Anthropometric measurements","Infant length measurements","Infant weight measurement","Head Circumference","Artificial Intelligence","Image based assessment","Digital Health","Photographs and video recordings","Neonatal intensive care unit","Special Care nursery","Observational study","Proof of concept study","Growth monitoring","RECRUITING","2026-04-08",{"date":50,"type":51},"2026-04-13","ACTUAL",{"date":53,"type":51},"2026-03-26",{"date":55,"type":22},"2026-10",{"name":57,"class":58},"Danone Asia Pacific Holdings Pte, Ltd.","INDUSTRY",1,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":67,"enrollmentInfo":68,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":4},"100632935","chest-x-rays-for-early-detection-of-congenital-heart-disease-in-newborns-100632935","NCT07520149","Chest X-Rays for Early Detection of Congenital Heart Disease in Newborns","Evaluation of Chest X-Ray Findings in Early Detection of Congenital Heart Disease in Neonates","Inclusion Criteria:\n\n* Neonates aged 0-28 days admitted to the NICU with X-ray findings suspecting CHD during the study period.\n* Neonates presenting with clinical signs suggestive of congenital heart disease, including: cyanosis (central or peripheral), heart murmur detected on auscultation, tachypnea, or respiratory distress.\n* Neonates with abnormal pulse oximetry findings (oxygen saturation \\\u003C95% in room air).\n* Neonates with abnormal antenatal ultrasound findings suggesting cardiac anomalies.\n\nExclusion Criteria:\n\n* Infants aged more than 28 days.\n* Infants with no clinical or radiological evidence of CHD.","28 Days",{"count":21,"type":22},"Congenital heart disease (CHD) is a common condition affecting newborns that can be serious if not caught early. While echocardiograms are the best way to diagnose CHD, they are not always immediately available. Chest X-rays are widely available and are often the first test used when a newborn has breathing problems, a heart murmur, or a bluish skin tint.\n\nThe purpose of this study is to determine how accurate standard chest X-rays are at finding congenital heart disease in newborns.\n\nResearchers will observe 60 newborns (up to 28 days old) admitted to the Neonatal Intensive Care Unit (NICU) who have signs or symptoms that suggest they might have a heart problem. Each baby in the study will receive a standard chest X-ray within 24 hours of their clinical presentation. Within 72 hours, they will also receive an echocardiogram, which is the standard, definitive test used to confirm if there is a heart defect.\n\nBy comparing the initial chest X-ray results to the final echocardiogram results, researchers hope to figure out exactly which X-ray patterns are best at predicting specific heart diseases. This could help doctors make faster decisions about treating newborns, potentially reducing delays in diagnosis and improving care.",[71,72,28],"Congenital Heart Disease","Chest X-ray for Clinical Evaluation",[71,74,28,75,76],"Chest X-Ray","Echocardiography","Chest Radiography","NOT_YET_RECRUITING","2026-04-03",{"date":80,"type":51},"2026-04-09",{"date":82,"type":22},"2026-05",{"date":84,"type":22},"2027-06",{"name":86,"class":87},"Assiut University","OTHER",{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":4,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":59},"100589196","music-therapy-during-hypothermia-in-the-nicu-100589196","NCT06951269","Music Therapy During Hypothermia in the NICU","The Effect of Music Therapy on Pain Levels in Neonates With Hypoxic-ischemic Encephalopathy During Hypothermia: a Randomized Pilot and Feasibility Study","Inclusion Criteria:\n\n\\- Neonates diagnosed with neonatal hypoxic ischemic encephalopathy who have undergone hypothermic therapy as part of their medical treatment.\n\nExclusion Criteria:\n\n* Newborns with a gestational age of less than 35 weeks and a birth weight of less than 1800 grams.\n* Newborns in palliative care or with congenital anomalies with a poor prognosis will also be excluded, as will those with preexisting neurological or genetic conditions.\n* Furthermore, newborns with a history of serious medical complications that may influence participation in the study, such as pulmonary hypertension or secondary seizure syndrome, will be considered ineligible.\n* Finally, patients with an N-PASS score of less than -2 will be excluded.","35 Weeks","44 Weeks",{"count":98,"type":22},22,"INTERVENTIONAL",[101],"NA","Background: Hypoxic-ischemic encephalopathy (HIE) is a neurological condition caused by poor oxygenation during the peripartum period. The main strategy to mitigate neurological damage is hypothermic therapy (HT), whose effectiveness-among other factors-depends on adequate pain management. Considering the prevalence of allodynia in this group of patients, routine nursing procedures can become sources of additional stress and pain. Music therapy is used in this population to promote self-regulation and relaxation, and may therefore help reduce pain levels after routine nursing procedures.\n\nResearch question: What is the effect of an entrainment-based live music therapy intervention on pain levels in newborns with hypoxic-ischemic encephalopathy undergoing hypothermic therapy after routine nursing procedures? Methodology: A randomized, crossover pilot and feasibility study. Participants will be 22 newborns admitted to the Neonatal Intensive Care Unit (NICU) of the University Hospital Fundación Santa Fe de Bogotá. Participants will receive standard care plus a 15-minute live music therapy session after a routine nursing procedure, or standard care alone. The primary outcome is the Premature Infant Pain Profile-Revised (PIPP-R) scale, which will be assessed through video recordings. Secondary outcomes are vital signs, heart rate variability, and electroencephalography (EEG) recordings.\n\nExpected outcomes: Through this study, the aim is to improve the comfort and well-being of patients with HIE during TH. In addition, the safety and feasibility of music therapy in this population will be evaluated, seeking to contribute to current knowledge about the mechanisms of music therapy.",[104,105,106,28,107,108],"Music Therapy","Pain","Allodynia","NICU","Hypothermia Neonatal","2025-09-17",{"date":111,"type":51},"2025-09-23",{"date":113,"type":22},"2025-10-30",{"date":115,"type":22},"2027-08-01",{"name":117,"class":87},"Fundación Santa Fe de Bogota",{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":67,"enrollmentInfo":124,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":126,"conditions":127,"keywords":4,"overallStatus":77,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":4},"100564261","predictive-value-of-scoring-system-in-neonates-with-disseminated-intravascular-coagulation-100564261","NCT06626880","Predictive Value of Scoring System in Neonates with Disseminated Intravascular Coagulation","Inclusion Criteria:\n\n1. age at enrollment from the first day of life to 28 days of life.\n2. Neonates diagnosed as DIC.\n\nExclusion Criteria:\n\n1. Neonates born to mothers with ITP.\n2. Autoimmune thrombocytopenic patients.",{"count":125,"type":22},43,"The aims of this study were to investigate underlying diseases associated with neonatal DIC diagnosed on the first 28 days of life, and whether DIC score could predict mortality in neonates.",[128,28],"Disseminated Intravascular Coagulation","2024-10-02",{"date":131,"type":51},"2024-10-04",{"date":133,"type":22},"2025-01-01",{"date":135,"type":22},"2026-03-29",{"name":86,"class":87}]