[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neostigmine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neostigmine":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100568782","phase-4-comparative-study-between-intrathecal-magnesium-sulfate-neostigmine-and-fentanyl-as-adjuvant-for-bubivacaine-in-postoperative-analgesia-in-lower-abdominal-surgeries-100568782",false,"NCT06685705","Comparative Study Between Intrathecal Magnesium Sulfate, Neostigmine and Fentanyl as Adjuvant for Bubivacaine in Postoperative Analgesia in Lower Abdominal Surgeries","Inclusion Criteria:\n\n* • the American Society of Anesthesiologists (ASA) classification I-II\n\n  * Age \\>18 up to 55 years old\n  * Both sex\n  * Patients who will undergo lower abdominal surgeries\n\nExclusion Criteria:\n\n* • Patients' refusal.\n\n  * Patients with morbid obesity, cardiac diseases, hepatic diseases, renal diseases, diabetes mellitus with polyneuritis.\n  * Patients who were in risk-scoring groups American Society of Anesthesia III-IV.\n  * Hypertensive patients receiving therapy with adrenergic receptor antagonist, calcium channel blocker and\u002For angiotensin converting enzyme inhibitor.\n  * Patients with coagulation disorders, those receiving any anticoagulants.\n  * Any history of allergy to local anesthetic or other drugs used in the study, patients on examining drugs.\n  * Any contraindication to spinal anesthesia ( infection at puncture site and increased intracranial tension and Patients with psychiatric illness and neurologic diseases.","ALL","18 Years","55 Years",{"count":19,"type":20},66,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","Lower abdominal surgeries often result in severe pain, which in turn can cause rapid and shallow breathing, retention of secretions and poor patient compliance. Justifiably, apart from the fear for the surgery outcome, patients are concerned mainly with postoperative pain. If treated inadequately, acute pain can have serious consequences for patient health mainly with postoperative complications, prolonged recovery and increased length of hospital stay. Higher levels of postoperative pain and pain distress are associated with increased morbidity, poorer functional recovery, and reduced quality of life.\n\nAim of the study To compare the duration, quality of analgesia, and side effects between intrathecal Magnesium sulfate, neostigmine and fentanyl as adjuvant for bubivacaine as postoperative analgesia in lower abdominal surgeries",[26,27,28],"Magnesium Sulfate","Neostigmine","Fentanyl",[30],"lower abdominal surgeries","NOT_YET_RECRUITING","2024-11-11",{"date":34,"type":35},"2024-11-12","ACTUAL",{"date":37,"type":20},"2024-12-01",{"date":39,"type":20},"2026-01-01",{"name":41,"class":42},"Assiut University","OTHER"]