[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nephrectomykidney-donation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nephrectomykidney-donation":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100623447","the-effects-of-transversalis-fascia-plane-block-on-opioid-consumption-in-patients-undergoing-hand-assisted-laparoscopic-donor-nephrectomy-a-randomized-controlled-prospective-study-100623447",false,"NCT07396753","The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Laparoscopic Donor Nephrectomy: A Randomized Controlled Prospective Study","Inclusion Criteria:\n\n* Approved by the transplant committee for living kidney donation\n* Scheduled for hand-assisted laparoscopic donor nephrectomy (HALDN)\n* Able to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy to any medications used in the study (e.g., local anesthetics, opioids)\n* Chronic opioid use or use of opioid receptor agonists\n* Inability to communicate effectively (e.g., cognitive impairment, language barrier)\n* Chronic organ failure or major organ dysfunction\n* Refusal or inability to provide informed consent\n* Foreign nationality (if follow-up or consent is restricted)\n* American Society of Anesthesiologists (ASA) physical status ≥ III","ALL","18 Years","80 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate whether a regional anesthesia technique called the transversalis fascia plane block (TFPB) can improve pain control after hand-assisted laparoscopic donor nephrectomy (HALDN), a minimally invasive surgery performed in living kidney donors.\n\nAlthough HALDN is less invasive than open surgery, patients often experience significant pain after the operation, mainly due to the surgical incisions in the lower abdomen and trocar entry sites. Poorly controlled pain can delay recovery and increase the need for opioid pain medications, which may cause side effects such as nausea, vomiting, itching, and sedation.\n\nThe transversalis fascia plane block is an ultrasound-guided regional anesthesia technique in which a local anesthetic is injected into a specific tissue plane in the lower abdominal wall. This injection temporarily blocks pain signals from nerves supplying the lower abdomen and groin area. The technique has been shown to reduce pain and opioid use after various lower abdominal surgeries and is considered minimally invasive and safe when performed under ultrasound guidance.\n\nIn this study, patients undergoing HALDN will be randomly assigned to one of two groups. One group will receive standard general anesthesia only, while the other group will receive general anesthesia plus a transversalis fascia plane block using a local anesthetic (bupivacaine). All patients will receive the same standard pain treatment after surgery, including paracetamol and patient-controlled morphine.\n\nThe main goal of the study is to compare the amount of opioid pain medication used during the first 24 hours after surgery between the two groups. Secondary outcomes include pain scores measured using the Numeric Rating Scale (NRS), the frequency of opioid-related side effects, and patient satisfaction with pain control.\n\nThe results of this study may help determine whether adding the transversalis fascia plane block to standard anesthesia can provide better pain relief, reduce opioid consumption, and improve comfort and recovery in living kidney donors.",[26,27,28,29,30,31],"Postoperative Pain","Analgesics, Opioid","Pain Management","Anesthesia Regional","Living Donors","Nephrectomy,Kidney Donation",[33,34,35,36],"Hand-assisted laparoscopic donor nephrectomy","Transversalis fascia plane block","Regional anesthesia","Opioid consumption","RECRUITING","2026-02-02",{"date":40,"type":41},"2026-02-09","ACTUAL",{"date":43,"type":41},"2025-07-25",{"date":45,"type":20},"2026-03-03",{"name":47,"class":48},"Koç University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100612512","a-qualitative-study-on-gratitude-and-recognition-toward-living-kidney-donors-100612512","NCT07254546","A Qualitative Study on Gratitude and Recognition Toward Living Kidney Donors","GRAtitude et Considération Envers Les Donneurs Vivants du Rein","GRACE","Inclusion Criteria:\n\n* Individuals who have donated a kidney at Hôpital Saint-Louis between January 1, 2020, and December 31, 2025, or are currently engaged in a living kidney donation process with nephrectomy scheduled before June 30, 2026.\n* Age ≥ 18 years.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Refusal or opposition to participate in the study.\n* Individuals under legal protection (guardianship, curatorship, or legal safeguard).\n* Individuals deprived of liberty by judicial or administrative decision.\n* Individuals under 18 years of age.\n* Kidney donation performed in a hospital other than Hôpital Saint-Louis.",true,{"count":60,"type":20},15,[23],"Kidney transplantation is widely recognized as the best treatment for patients with end-stage renal disease. However, its development is limited by the persistent shortage of available organs. Living donor kidney transplantation offers the best functional and survival outcomes, yet the number of procedures remains insufficient.\n\nLiving kidney donation relies on a voluntary and altruistic act by a healthy individual who accepts surgery without direct medical benefit. This act of generosity raises important questions regarding how society acknowledges and values such commitment. The lack of formal recognition may contribute to the psychological burden experienced by some donors and may not adequately reflect the gratitude of the medical community and society toward them.\n\nThis study aims to explore the perceptions of living kidney donors regarding the potential implementation of a symbolic form of recognition (for instance, a commemorative medal) offered after donation. The hypothesis is that such recognition could improve donors' post-donation experience and strengthen the societal value associated with living organ donation, while fully respecting ethical principles prohibiting any financial reward.\n\nThis is a qualitative, monocentric study based on semi-structured interviews with individuals who have donated a kidney. The interviews will focus on donors' motivations, their personal experience of donation, and their opinions about different possible forms of post-donation recognition. Interviews will be recorded, transcribed verbatim, and analyzed using inductive thematic analysis to identify recurring themes and perspectives.\n\nThe main endpoint is the identification of thematic categories related to donors' perception of post-donation recognition and its potential impact on their experience. Secondary objectives include exploring donors' expectations regarding societal gratitude, their views on the symbolic value of such recognition, and the potential influence on future donor engagement.\n\nThe findings of this study are expected to contribute to the ethical reflection surrounding the acknowledgment of living donors, support initiatives promoting non-financial recognition, and help develop respectful and meaningful ways of expressing societal gratitude toward those who make the gift of life possible.",[64,31],"Kidney Transplantation",[66,67,68,69,70],"Incentive","Living donor","Living donor nephrectomy","Living kidney donation","Gratitude","NOT_YET_RECRUITING","2025-11-25",{"date":74,"type":41},"2025-11-28",{"date":76,"type":20},"2026-01-01",{"date":78,"type":20},"2026-08-01",{"name":80,"class":48},"Assistance Publique - Hôpitaux de Paris"]