[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nerve-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nerve-pain":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100560897","ultrasound-guided-radiofrequency-ablation-of-the-occipital-nerve-100560897",false,"NCT06583122","Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve","Inclusion Criteria:\n\n* Patients between the ages of 18-80 with a diagnosis of occipital neuralgia or migraine overlying the occipital region.\n* A diagnosis of occipital neuralgia will be based on the International Classification of Headache Disorders (ICHD), whose criteria include: paroxysmal stabbing pain in the distribution of the GON, tenderness over the affected nerve, and relief of pain for at least 3 hours after bupivacaine local anesthetic block of the affected nerve.\n* Patients may also be included if they have a diagnosis of migraine based on the ICHD criteria with predominance of pain over the occipital region that responded to occipital nerve block.\n* Patients must have failed oral medications including NSAIDs, opioids, and anticonvulsants for the management of their pain.\n* Failed treatment will be \\\u003C50% pain reduction with oral medication.\n* Patients must report headache frequency of at least 10 days per month.\n\nExclusion Criteria:\n\n* Patients will be excluded from the trial if they have an unstable medical or psychological condition,\n* are pregnant,\n* have an implanted cardiac pacemaker or defibrillator that could not be disabled,\n* have had a craniotomy or scar tissue overlying the site from a previous surgery,\n* have a history of cervical spine fusion,\n* have evidence of elevated ICP or intracranial tumor,\n* or have previous RFA treatment of the greater or lesser occipital nerve.","ALL","18 Years","80 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","Study an ultrasound guided approach to radiofrequency ablation of the occipital nerve that makes it possible to see the needle during treatment procedure. It is hoped this will reduce the amount of pain after the standard of care procedure.",[26],"Nerve Pain","RECRUITING","2025-04-08",{"date":30,"type":31},"2025-04-09","ACTUAL",{"date":33,"type":31},"2022-07-01",{"date":35,"type":20},"2026-12-31",{"name":37,"class":38},"University of Kansas Medical Center","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":52,"conditions":53,"keywords":57,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100562129","phase-1-petmri-for-chronic-pain-from-spinal-or-peripheral-nerve-origin-100562129","NCT06599151","PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin","Use of (18F)FTC-146 PET_MRI for Characterizing Chronic Pain Phenotypes in Chronic Pain Patients with Spinal or Peripheral Nerve Origin","Inclusion Criteria:\n\n* Healthy Volunteers\n\n  1\\. At least 18 years old.\n* Pain Subjects\n\n  1. At least 18 years old.\n  2. Chronic Pain is of Spinal or Peripheral Nerve Origin\n  3. Subject's Chronic pain lasting greater than 2 months.\n  4. Pain level of at least 4\u002F10 on a 0-10 Comparative Pain Scale.\n\nExclusion Criteria:\n\n* Healthy Volunteers\n\n  1. Any chronic Pain\n  2. Use of pain medication.\n  3. MRI incompatibility.\n  4. Kidney problems.\n  5. Pregnant or nursing.\n  6. Non-English speaker.\n  7. Presence of vasculopathy or Raynaud's.\n  8. Inability to tolerate cessation of anticoagulant medication during the study.\n* Pain Subjects\n\n  1. MRI incompatibility.\n  2. Kidney problems.\n  3. Pregnant or nursing.\n  4. Non-English speaker.",true,{"count":49,"type":20},200,[51],"PHASE1","The purpose of this study is to compare the uptake of \\[18F\\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.\n\nPrimary Objectives:\n\nA) To quantify the bio-distribution of \\[18F\\] FTC-146 uptake in subjects with Spinal or Peripheral Nerve Origin pain and compare it with healthy controls.\n\nB) To determine whether painful schwannomas can be differentiated from non-painful schwannomas based on imaging.\n\nSecondary Objectives:\n\nA) To assess the reproducibility of \\[18F\\]FTC-146 PET imaging within the same healthy volunteer subjects using Test-Retest analysis.\n\nB) To investigate whether post-treatment \\[18F\\]FTC-146 uptake differs from pre-treatment uptake and correlate the imaging with subject reported pain level after treatment",[26,54,55,56],"Neuropathic Pain","Nociceptive Pain","MIxed Pain (Nociceptive and Neuropathic)",[58,59,26],"PET\u002FMRI","Chronic Pain","NOT_YET_RECRUITING","2024-09-12",{"date":63,"type":31},"2024-09-19",{"date":65,"type":20},"2024-10-01",{"date":67,"type":20},"2030-10-01",{"name":69,"class":38},"Stanford University"]