[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neural-inhibition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neural-inhibition":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100629039","the-effects-of-high-dose-vitamin-b6-on-depression-and-anxiety-symptoms-100629039",false,"NCT07469462","The Effects of High-dose Vitamin B6 on Depression and Anxiety Symptoms","An EEG Study to Investigate the Effect of High-dose Vitamin B6 Supplementation on Neural Activity in Relation to Depression and Anxiety Symptoms.","Inclusion Criteria:\n\n* Over 18 years of age and under 41\n* Mild to moderate anxiety and\u002For depression\n* Normal or corrected to normal vision\n\nExclusion Criteria:\n\n* not taking daily dietary supplement containing \\>2 mg Vitamin B6\n* not taking medication that is a GABA agaonist (our team will check this with you)\n* not be pregnant\n* no medical history of epilepsy\n* no medical history of peripheral neuropathy\n* not taking the antibiotic Seromycin (prescribed for tuberclosis or urinary tract infection)\n* no history of brain injury or recent concussion",true,"ALL","18 Years","41 Years",{"count":21,"type":22},44,"ESTIMATED","INTERVENTIONAL",[25],"NA","This clinical trial investigates the effects of Vitamin B6 supplementation on neural inhibition using electroencephalography (EEG), in relation to depression and anxiety symptoms in participants from the general population with a relatively high level of symptoms at baseline. Researchers will compare a placebo group to high-dose Vitamin B6 to test the hypothesis that Vitamin B6 moves the excitation\u002Finhibition balance towards inhibition.",[28,29,30],"Neural Inhibition","Anxiety","Depression",[32,33,34,35,30,29],"Vitamin B6","Excitation-Inhibition Balance","GABA","Electroencephalograpgy","RECRUITING","2026-04-27",{"date":39,"type":40},"2026-04-28","ACTUAL",{"date":42,"type":22},"2026-05-01",{"date":44,"type":22},"2026-11",{"name":46,"class":47},"University of Reading","OTHER"]