[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuralgia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuralgia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,71,93],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100546738","virtual-reality-vr-self-hypnosis-software-100546738",false,"NCT06398847","Virtual Reality (VR) Self-Hypnosis Software","An Open-label Study of Self-hypnosis Software for Virtual Reality for the Treatment of HIV-associated Chronic Pain - a Development and Usability Study","Patient Eligibility\n\nInclusion Criteria:\n\n* Adults age ≥18\n* Confirmed diagnosis of HIV, currently on a stable antiretroviral regimen ≥ 90 days.\n* Documentation of chronic pain associated with HIV for≥90 days\n* Stable pain management regimen ≥90 days, or no pain treatments ≥90 days\n* Average pain intensity of 3 or greater on the NRS of the mean daily scores reported between Visit 1 and Visit 2\n* Access to the internet via smartphone, computer, or tablet 7. Fluent in English\n* Capable of giving informed consent and willingness to comply with study procedures.\n\nExclusion Criteria:\n\n* A co-occurring medical or psychiatric condition which would make participation in the study or complicate measurement of changes associated with the intervention.\n* Concurrent participation in another investigational protocol for pain treatment\n* A psychiatric disorder, medical condition, or other life circumstance, which in the opinion of the PI, would contraindicate attendance at sessions, or make it unlikely that the participant could successfully complete the study procedures.\n* Current or prior diagnosis of epilepsy, seizure disorder, dementia, migraines, or other neurological conditions contraindicating the use of virtual reality devices.\n* A medical condition predisposing prospective participant to nausea or dizziness 6. Lack of stereoscopic vision or severe hearing impairment\n* Injury to eyes, face, or neck that impedes using the VR device\n* If participant has access to personal VR gear for gaming or other purposes at home, participant fails to agree not to use these personal VR gear during the course of the protocol.\n* Currently pregnant or planning to become pregnant during the study period","ALL","18 Years",{"count":19,"type":20},25,"ESTIMATED","INTERVENTIONAL",[23],"NA","This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic pain patients. This is funded under the i Prism Funding through Mount Sinai Innovations.",[26,27,28],"Musculoskeletal Pain","Neuropathic Pain","Neuralgia",[30,31,32,33],"HIV chronic pain","Self-hypnosis","virtual reality software","non-drug treatment for chronic pain","RECRUITING","2026-03-27",{"date":37,"type":38},"2026-04-02","ACTUAL",{"date":40,"type":38},"2026-03-26",{"date":42,"type":20},"2026-06-30",{"name":44,"class":45},"Icahn School of Medicine at Mount Sinai","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100502094","treatment-of-upper-limb-chronic-neuropathic-pain-by-electrical-stimulation-of-the-brachial-plexus-nerve-roots-100502094","NCT05817786","Treatment of Upper Limb Chronic Neuropathic Pain by Electrical Stimulation of the Brachial Plexus Nerve Roots","SIMPLEX","Inclusion Criteria:\n\n* Eligibility will be determined by trained clinicians with expertise in chronic pain and neuropathic pain.\n* Patients between 18 and 80 years old\n* suffering from moderate to severe (VAS score \\>5\u002F10) chronic (duration\\> 12 months) neuropathic (DN4 score ≥ 4\u002F10) unilateral pain - located in the upper limb.\n* from peripheral origin, including complex regional pain syndrome type I and II, post-traumatic or post surgical pain.\n* refractory to first and second line treatments for neuropathic pain according recent French recommendations and guidelines\\[6\\], including serotonin- noradrenaline reuptake inhibitor (SNRI) antidepressants (duloxetine and venlafaxine), gabapentin, pregabalin, tricyclic antidepressants, topical lidocaine, high-concentration capsaicin patches, psychotherapy and combinations of them.\n\nPatient have signed informed consent\n\n\\- Patient benefiting from French social insurance system\n\nExclusion Criteria:\n\n* Brachial plexus avulsion\n* Post-zoster neuropathic pain\n* Phantom limb pain\n* Patient unable to fill a self-administered questionnaire\n* Patients with a chronic disease requiring repeated MRI monitoring\n* Patients with contra-indication to general anesthesia, surgery or percutaneous BP approach.\n* Patients with other pacemakers (cardiac pacemaker or defibrillator) or patients with a high risk to use a defibrillator due to a known cardiac disorder.\n* Patients with instable neuropsychological or psychiatric disorders\n* Vulnerable patients: pregnant or breast feeding, minor, adult under guardianship or deprived freedom","18 Months","80 Years",{"count":57,"type":20},48,[23],"Moderate to severe neuropathic pain has a prevalence of 5% in the French population, involving the upper limb (UL) in 47%. Invasive neuromodulation, mainly spinal cord stimulation (SCS) is recommended as a third line treatment in refractory chronic neuropathic pain when optimized medical treatments are not sufficient to control pain.\n\nThe implantation technique for BP roots PNS is based on the ultrasound-guided percutaneous inter-scalenic approach, routinely used for BP anesthetic blocks. As for SCS, BP PNS relies on chronic electrical stimulation of the nerve roots via chronically implanted devices (one lead connected to a subcutaneous generator).\n\nHowever efficacy of BP PNS has never been evaluated in controlled conditions. Our objectives are to assess, in controlled conditions, the effects of BP PNS in term of pain relief, quality of life improvement and safety.",[28],"2025-03-18",{"date":63,"type":38},"2025-03-19",{"date":65,"type":38},"2024-02-09",{"date":67,"type":20},"2027-07-01",{"name":69,"class":45},"Centre Hospitalier Universitaire de Nice",3,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":80,"phases":4,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":46},"100577307","perioperative-medical-program-to-optimize-nerve-regeneration-after-robot-assisted-laparoscopic-neurolyses-of-pudendal-andor-inferior-cluneal-nerves-for-chronic-neuralgias-results-after-1-year-follow-up-100577307","NCT06796595","Perioperative Medical Program to Optimize Nerve Regeneration After Robot-assisted Laparoscopic Neurolyses of Pudendal and\u002For Inferior Cluneal Nerves for Chronic Neuralgias: Results After 1-year Follow-up","REGEN","Inclusion Criteria:\n\n* Patients over 18 years old\n* Patients presenting a pudendal and\u002For inferior cluneal neuralgias with failure of the medical treatment\n* Patient having given consent after reading the information note\n\nExclusion Criteria:\n\n* Inoperable patients (contraindications to anesthesia or surgery) surgical contraindications)\n* Person deprived of liberty or under guardianship\n* Person under court protection\n* Pregnant or breast-feeding woman\n* Minors",{"count":79,"type":20},20,"OBSERVATIONAL","Pudendal and inferior cluneal neuralgias are responsible for chronic pelvicperineal pain. These two neuralgias are associated in approximately 25% of cases. In the event of failure of first-line multimodal medical treatment, a mini-invasive robot-assisted laparoscopic decompression can be proposed. These surgeries carry the risk of neurapraxia, leading to a temporary increase in neuropathic pain and numbness in the nerve sensitive area, a motoric or neurovegetative disturbance (pudendal).",[83,28],"Pudendal Neuralgia","2025-01-27",{"date":86,"type":38},"2025-01-28",{"date":88,"type":20},"2025-01-23",{"date":90,"type":20},"2027-01-31",{"name":92,"class":45},"UBOSGA",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":80,"phases":4,"briefSummary":102,"conditions":103,"keywords":106,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":46},"100193015","mri-guided-cryoablation-to-alleviate-pain-in-head-neck-and-spine-100193015","NCT01788410","MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine","MRI-Guided Cryoablation of Head, Neck and Spine Nerves and Facets Using the Advanced Multimodality Image Guided Operating(AMIGO) Suite","Inclusion Criteria:\n\n* Participants must be willing and able to sign a written informed consent document.\n* Patients must have facet joint disease or pain due to a damaged or compressed nerve that would benefit from a minimally invasive image-guided procedure (i.e., adjacent to critical structures, better visualized under 3 Tesla MRI than CT)\n* Subjects must be able to adhere to the visit schedules and attend pre and post imaging.\n* Participants must be at least 18 years of age\n* Participants must have an estimated life expectancy of \\>8 weeks in the opinion of the clinician.\n\n  * Patients with radiculopathy must have the cause of pain confirmed by a nerve block within 3 months prior to ablation\n\nExclusion Criteria:\n\n* Contraindications to MRI and Gadolinium- (i.e. estimated Glomerular Filtration Rate \\\u003C60ml\u002Fmin, metal clips)\n* Pregnant or breastfeeding woman are excluded from this research.",{"count":101,"type":20},50,"The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root. The goal is to provide palliative care with superior efficacy and longer relief compared to current methods.",[104,105,28],"Facet Joints; Degeneration","Neuropathy",[107,108,109,110,28,105,111],"Cryoablation","Nerves","Facet joint","Pain","Image-guided","2023-08-07",{"date":114,"type":38},"2023-08-08",{"date":116,"type":4},"2013-05",{"date":118,"type":20},"2030-05",{"name":120,"class":45},"Brigham and Women's Hospital"]