[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuroaxial-analgesia-procedures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuroaxial-analgesia-procedures":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100621977","phase-4-intrathecal-morphine-versus-transabdominal-plane-block-tap-block-for-analgesic-management-in-elective-caesarean-section-100621977",false,"NCT07377630","Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section","Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section Performed Under Neuraxial Anesthesia. A Monocentric Pilot Randomized Controlled Trial","MIRAGE","Inclusion Criteria:\n\n* Planned for elective Cesarean Section (CS)\n* Scheduled for spinal anesthesia\n* Gestational age \\> 34 weeks\n* Age 18 years or above\n* Ability to read and understand the information sheet and to sign and date the consent form\n\nExclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) classification \\>2\n* Body Mass Index (BMI) ≥ 40 kg\u002Fm2\n* Weight \\\u003C 50 kg\n* Height \\\u003C 150 cm or ≥ 180 cm\n* Complicated Pregnancy (abnormal placentation, preeclampsia or others)\n* Women with opioid use disorder\n* Contraindication to spinal anesthesia (clotting disorder, local infection, spinal malformation, elevated intracranial pressure)\n* Contraindication to Transabdominal Plane Block (TAP) block (skin infection, abdominal wall muscle defects)\n* Allergy\u002Fcontraindication to any medication used in the study\n* Previous median abdominal incision\n* Emergency or unplanned CS","FEMALE","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The goal of this randomized controlled clinical trial is to determine if low-dose intrathecal morphine is superior to a Transversus Abdominis Plane (TAP) block with ropivacaine and clonidine for postoperative analgesia in women aged 18 years or older undergoing elective cesarean section under neuraxial anesthesia.\n\nThe main questions it aims to answer are:\n\n* Is intrathecal morphine more effective than TAP block in reducing postoperative somatic pain at rest?\n* Does intrathecal morphine differ from TAP block in terms of adverse events, pain during mobilization, visceral pain, rescue analgesic use, maternal satisfaction, and newborn wellbeing?\n\nResearchers will compare the intrathecal morphine (ITM) group to the TAP block (TB) group to see if ITM provides superior analgesia and improved secondary outcomes.\n\nParticipants will:\n\n* Undergo spinal anesthesia with hyperbaric bupivacaine and sufentanil\n* add 30 μg intrathecal morphine (only ITM group)\n* receive bilateral ultrasound-guided TAP block with 20 ml ropivacaine 0.25% and 75 μg clonidine per side (only TB group)\n* receive standardized postoperative analgesia with paracetamol, ibuprofen, and tramadol as needed\n* be monitored postoperatively for pain (somatic and visceral, at rest and with movement), adverse events, mobilization, maternal satisfaction, and newborn outcomes at regular intervals for 24 hours\n\nThis is a single-center, pilot, single-blind trial involving 100 participants (50 per group).",[27,28,29],"Pregnancy","Cesarean Section","Neuroaxial Analgesia Procedures",[31,32,33,34],"cesarean section","neuraxial anesthesia","TAP block","morphine","NOT_YET_RECRUITING","2026-01-22",{"date":38,"type":39},"2026-01-30","ACTUAL",{"date":41,"type":21},"2026-03-01",{"date":43,"type":21},"2027-03-02",{"name":45,"class":46},"Istituto Giannina Gaslini","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":47},"100531602","epidural--evaluation-of-preexisting-information-regarding-neuroaxial-procedures-for-labour-analgesia-100531602","NCT06201936","EPIDURAL- Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia","Evaluation of Preexisting Information Regarding Neuroaxial Procedures for Labour Analgesia","EPIDURAL","Inclusion Criteria:\n\n* Pregnant women prior to delivery\n\nExclusion Criteria:\n\n* Women under 18 years of age","65 Years",{"count":58,"type":21},1000,"OBSERVATIONAL","The aim of this research project is to anonymously survey pregnant patients before the anaesthesiological consultation about their prior knowledge of planned neuroaxial procedures in the context of childbirth by conducting an online survey and to evaluate the sources of that information.",[29],"RECRUITING","2025-05-05",{"date":65,"type":39},"2025-05-07",{"date":67,"type":39},"2025-03-01",{"date":69,"type":21},"2026-11-01",{"name":71,"class":46},"Goethe University"]