[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neurogenic-bowel-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neurogenic-bowel-dysfunction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,63,92],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100609392","vibrant-capsule-for-spinal-cord-injury-neurogenic-bowel-dysfunction-100609392",false,"NCT07213986","Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction","Pilot Trial of the Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction","Inclusion Criteria:\n\n* Individuals with chronic spinal cord injury (SCI) of more than one year.\n* Stable neurological level and function of SCI for at least six months.\n* Consistent bowel program without changes for at least 3 months.\n* At least one scheduled bowel movement (BM) every three days.\n* Use of digital stimulation, suppositories, enemas, or mini enemas, as part of the scheduled bowel program.\n* Use of oral medications as part of the bowel program.\n\nExclusion Criteria:\n\n* Bowel incontinence occurring more than once per week.\n* Non-English-speaking individuals.\n* History of bowel obstruction, ileus, diverticulitis, or bowel surgery for a disease (appendix removal is ok).\n* Persistent autonomic dysreflexia (AD) triggered by bowel movements.\n* Recent changes to spasticity medications within the past month.\n* History of significant gastrointestinal disorders\n* History of Zenker's diverticulum\n* Dysphagia\n* Esophageal stricture\n* Eosinophilic esophagitis or achalasia\n* Pregnancy.\n* Presence of implanted devices that could be affected by proximity to a direct current magnetic field.","ALL","21 Years",{"count":19,"type":20},12,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to test the safety and effectiveness of Vibrant capsules in spinal cord injury patients with neurogenic bowel.",[26,27],"Neurogenic Bowel Dysfunction","Spinal Cord Injury","RECRUITING","2026-04-29",{"date":31,"type":32},"2026-05-01","ACTUAL",{"date":34,"type":32},"2026-01-06",{"date":36,"type":20},"2026-08-19",{"name":38,"class":39},"The University of Texas Health Science Center, Houston","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":40},"100522098","stimulation-for-bowel-emptying-100522098","NCT06078176","Stimulation for Bowel Emptying","Electrical Rectal Stimulation to Promote Bowel Emptying After Spinal Cord Injury","Inclusion Criteria:\n\n* Suprasacral spinal cord injury\n* Diagnosed neurogenic bowel dysfunction and using digital rectal stimulation\n* Bowel routine requires at least 30 minutes or at least 3 cycles of digital rectal stimulation\n* Neurologically stable\n* At least 18 years old\n* At least 12 months post neurological injury or disease diagnosis\n\nExclusion Criteria:\n\n* Active sepsis\n* Open pressure sores on or around pelvis\n* Significant colon trauma or colostomy\n* Crohn's disease\n* Colonic obstruction or gastrointestinal surgery within last 3 months\n* Significant history of autonomic dysreflexia","18 Years",{"count":19,"type":20},[23],"The investigators are testing the effect of electrical stimulation of the rectum on colonic motility. Most individuals with spinal cord injury develop neurogenic bowel dysfunction, which includes slowed colonic motility, which means that stools take longer than normal to pass through the colon. This slowed movement may result in chronic constipation and difficulty emptying the bowels. Individuals typically (without or without caregiver assistance) insert a gloved finger into the rectum and gently stretch it to improve colonic motility for a brief period to empty the bowels. The investigators hypothesize that electrically stimulating the rectum, instead of mechanically stretching it, will produce the same beneficial effect of improving colonic motility. Therefore, this study will compare the two methods. If electrical stimulation effectively improves colonic motility, then the investigator shall develop the approach as a therapeutic intervention in future studies.",[26],"2026-04-07",{"date":55,"type":32},"2026-04-13",{"date":57,"type":32},"2024-05-01",{"date":59,"type":20},"2026-12-31",{"name":61,"class":62},"VA Office of Research and Development","FED",{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":16,"minAge":48,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":21,"phases":75,"briefSummary":76,"conditions":77,"keywords":78,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":4},"100621340","artificial-int-neurogenic-bowel-education-in-spinal-cord-injury-patients-100621340","NCT07369349","Artificial Int: Neurogenic Bowel Education in Spinal Cord Injury Patients","Artificial Intelligence Application of Neurogenic Bowel Training in Patients With Spinal Cord Injury","ArtInt","Inclusion Criteria:\n\n* Volunteers who consent to participate.\n* Age over 18 years.\n* Diagnosed with spinal cord injury (SCI).\n* Diagnosed with neurogenic bowel dysfunction (NBD).\n* Not in spinal shock (return of the bulbocavernosus reflex).\n* Having received routine NBD education at the study center within the last month.\n\nExclusion Criteria:\n\n* Individuals with mental retardation.\n* Individuals with visual and\u002For hearing impairments.\n* Individuals with communication problems.\n* Individuals with a history of additional injuries other than SCI (e.g., head trauma, pelvic injury, pelvic surgery).\n* Individuals diagnosed with neurological disorders such as stroke, Parkinson's disease, polyneuropathy, or multiple sclerosis.\n* Individuals with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD).\n* Individuals diagnosed with gastrointestinal malignancy.",true,"65 Years",{"count":74,"type":20},34,[23],"The aim of this study is to evaluate the effectiveness of patient education delivered through an artificial intelligence (AI)-based mobile application in the management of neurogenic bowel dysfunction in individuals with spinal cord injury. Within the scope of the study, it will be examined whether the mobile application reduces neurogenic bowel scores, contributes to maintaining stool scores within the normal range, and improves the quality of life of individuals. Accordingly, the AI-based education model to be developed is expected to facilitate the integration of bowel management practices into daily life, prevent complications, and enhance social participation.\n\n\\-",[27,26],[79,80,81],"spinal cord injury","neurogenic bowel dysfunction","Artificial Intelligence","NOT_YET_RECRUITING","2026-01-17",{"date":85,"type":32},"2026-01-27",{"date":87,"type":20},"2026-02-20",{"date":89,"type":20},"2026-11-01",{"name":91,"class":39},"Senem Duman",{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":16,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":21,"phases":103,"briefSummary":104,"conditions":105,"keywords":111,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":122},"100467649","non-invasive-spinal-cord-stimulation-for-recovery-of-autonomic-function-after-spinal-cord-injury-100467649","NCT05369520","Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury","Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury: Moving From Mechanisms to Clinical Practice","Inclusion Criteria:\n\n1. Resident of British Columbia, Canada with active provincial medical services plan.\n2. Male or female, 19-60 years of age.\n3. Chronic traumatic SCI (non-progressive, with complete motor paralysis) at or above the T6 spinal segment.\n4. \\>1-year post injury, at least 6 months from any spinal surgery.\n5. American Spinal Injury Association Impairment Scale (AIS) A, B.\n6. Stable management of spinal cord related clinical issues (i.e., spasticity management).\n7. Experience bladder, or bowel, or sexual dysfunction.\n8. No painful musculoskeletal dysfunction, unhealed fracture, pressure sore, or active infection that may interfere with testing.\n9. For women of childbearing potential, not intending to become pregnant, currently pregnant, or lactating. The following conditions apply:\n\n   1. A confirmed negative pregnancy test prior to the baseline visit. During the trial, all women of childbearing potential will undergo urine pregnancy tests at their monthly clinic visits as outlined in the schedule of events.\n   2. Use adequate contraception, or complete abstinence from sexual activities, during the period of the trial and for at least 28 days after completion of treatment.\n   3. If using combined hormonal contraception, a stable regimen during the period of the trial and for at least 28 days after completion of treatment.\n10. For sexually active males with female partners of childbearing potential, use adequate contraception, or complete abstinence from sexual activities, during the period of the trial and for at least 28 days after completion of treatment.\n11. Must provide informed consent.\n12. Willing and able to comply with all clinic visits and study-related procedures.\n13. Able to understand and complete study-related questionnaires (must be able to understand and speak English or have access to an appropriate interpreter as judged by the investigator).\n\nExclusion Criteria:\n\n1. Ventilator dependent.\n2. Signs of lower motor neuron damage (i.e. concomitant conus medullaris\u002Fcauda equina injury).\n3. Severe anemia or hypovolemia as measured by hematocrit via blood test in the last six months.\n4. History of cardiovascular, respiratory, bladder, or renal disease unrelated to SCI or presence of hydronephrosis or presence of obstructive renal stones.\n5. History of seizures\u002Fepilepsy or recurring headaches.\n6. Clinically significant, unmanaged, depression (to be screened) or ongoing drug abuse.\n7. Intrathecal baclofen pump.\n8. Oral baclofen dose greater than 60mg.\n9. Individuals that have received intradetrusor or intrasphincter onabotulinumtoxinA injections within 6 months of baseline.\n10. Any implanted metal (other than dental implants) in the skull or presence of pacemakers, stimulators, or medication pumps in the trunk.\n11. Past electrode implantation surgery.\n12. Member of the investigational team or his\u002Fher immediate family.\n13. Presence of severe acute medical issue and use of any specific medication or treatment that, in the investigator's judgement, would adversely affect the participant's participation in the study.\n14. Known allergies or sensitivities to both blue dye and beetroot powder.\n15. Known or suspected gastrointestinal obstruction.\n16. Persons with active inflammatory bowel disease or a history of bowel perforation.","19 Years","60 Years",{"count":102,"type":20},30,[23],"This study is a pilot clinical trial to explore the efficacy of transcutaneous spinal cord stimulation (TCSCS) (proof-of-concept) in mitigating crucial autonomic dysfunctions that impact the health-related quality of life of individuals with spinal cord injury (SCI).",[27,106,107,108,26,109,110],"Autonomic Dysfunction","Sexual Dysfunction","Neurogenic Bladder Dysfunction","Autonomic Dysreflexia","Orthostatic Hypotension",[112,27],"Neurostimulation","2025-12-01",{"date":115,"type":32},"2025-12-08",{"date":117,"type":32},"2023-10-03",{"date":119,"type":20},"2027-10",{"name":121,"class":39},"University of British Columbia",2]