[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neurologic-signs\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neurologic-signs":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100540139","multidimensional-evaluation-of-patients-affected-by-obstructive-apnea-syndrome-osas-before-and-after-ventilotherapy-100540139",false,"NCT06312956","Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy","MULTI-OSAS","Inclusion Criteria:\n\n* OSAS diagnosis (AHI \\> 5)\n* handedness: right\n\nExclusion Criteria:\n\n* previous ventilotherapy\n* neurological and\u002For neurodegenerative conditions\n* Personality disorders, autism spectrum disorders, schizophrenia, psychosis\n* sleep disorders comorbidities (eg., narcolepsy)","ALL","20 Years","60 Years",{"count":20,"type":21},65,"ESTIMATED","OBSERVATIONAL","This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.\n\nSpecifically, the study aims to identify pre- vs post-treatment differences in the following domains:\n\n* cognitive performance\n* blood expression of biomarkers related to neurodegeneration\n* psychosocial wellbeing\n\nThus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy:\n\n* neuropsychological standard assessment\n* blood sampling\n* psychosocial self-reported questionnaires",[25,26,27,28,29,30],"Obstructive Sleep Apnea","Sleep Disorder","Well-Being, Psychological","Cognitive Impairment","Cognitive Change","Neurologic Signs","RECRUITING","2025-09-02",{"date":34,"type":35},"2025-09-09","ACTUAL",{"date":37,"type":35},"2024-02-29",{"date":39,"type":21},"2026-12",{"name":41,"class":42},"Istituto Auxologico Italiano","OTHER"]