[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuromotor-impairments\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuromotor-impairments":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,79,103,131],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100644424","ai-based-model-for-rehabilitation-engagement-and-motor-performance-evaluation-in-pediatric-patients-a-pilot-study-100644424",false,"NCT07664033","AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients: A Pilot Study","AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients","AI-REMAP","Inclusion Criteria:\n\n* Subjects aged between 5 and 17 years with neuromotor impairments who are undergoing rehabilitation therapy using the Lokomat and GRAIL devices, according to the existing clinical plan.\n\nExclusion Criteria:\n\n* Uncooperative subjects.","ALL","5 Years","17 Years",{"count":21,"type":22},15,"ESTIMATED","INTERVENTIONAL",[25],"NA","What is the purpose of this study? This study aims to evaluate the usability and feasibility of an artificial intelligence-based model designed to monitor in real-time the engagement and motor performance of pediatric patients during technology-assisted rehabilitation.\n\nWho can take part? 15 participants between 5 and 17 years old with neuromotor impairments will take part, along with at least 5 of their referring physiotherapists.\n\nWhat will happen in the study? Each pediatric patient will take part in a single, 1-hour rehabilitation session using either the Lokomat or GRAIL system, according to their standard clinical prescription. During the session, the physiotherapist will have access to a display showing real-time data from the AI model, including the patient's heart rate, engagement level, pleasantness, activation, and motor performance. At the end of the session, the physiotherapist will complete a System Usability Scale (SUS) questionnaire and provide direct feedback on how to improve the model.\n\nWhy is this study important? Assessing the usability of this real-time monitoring tool is a necessary step to understand if it is practical for clinical use. Providing therapists with objective, real-time insights into a child's psychological and physical state can ultimately help tailor therapy to the specific needs of each patient, improving the overall rehabilitation experience.",[28],"Neuromotor Impairments",[30,31,28,32,33,34],"Engagement","Pediatric Rehabilitation","Gait","Heart Rate Variability","Electrodermal Activity","NOT_YET_RECRUITING","2026-06-17",{"date":38,"type":39},"2026-06-23","ACTUAL",{"date":41,"type":22},"2026-06-15",{"date":43,"type":22},"2026-09-30",{"name":45,"class":46},"IRCCS Eugenio Medea","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":19,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100584308","physical-therapy-for-montana-children-with-nmd-using-hippotherapy-and-the-equine-environment-100584308","NCT06887647","Physical Therapy for Montana Children With NMD Using Hippotherapy and the Equine Environment","Inclusion Criteria:\n\n* 1\\) 6-17 years old; 2) Diagnosed NMD with upper extremity impairment; 3) Able to follow simple verbal instructions in English; 4) Able to tolerate sitting on a horse continuously for 30 minutes; and 5) Meet Professional Association of Therapeutic Horsemanship International (PATH Intl.) standards for participating in mounted activities.\n\nExclusion Criteria:\n\n* 1\\) Fear of or aversion to horses; 2) Weight over 200lbs (to protect safety and wellbeing of therapists and equines) 3) Participation in a horseback-riding program in the past 3 months; 4) Lacking independent head control; and 5) Caregivers unable to speak and read English.","6 Years",{"count":56,"type":22},24,[25],"The goal of this pilot clinical trial is to determine if physical therapy incorporating horses can improve the motor skills of the arms in children 6-17 years old with neuromotor disorders (such as cerebral palsy, spinal muscular atrophy, or spina bifida) compared to standard play-based physical therapy. The main questions it aims to answer are:\n\n1. Is the study protocol feasible and acceptable for participants, that investigators could apply them to a larger trial?\n2. Do participants make improvements toward their goals for motor function, arm use, and participation in life situations following treatment, and is it different between the experimental and comparative intervention groups?\n3. What are the physiological, behavioral, and emotional responses of children receiving physical therapy incorporating horses, versus those receiving standard physical therapy?\n\nResearchers will compare the experimental group who receive physical therapy incorporating horses to the comparative intervention group who receive standard play-based physical therapy to see if there is a difference in outcomes.\n\nParticipants will complete a pre- and post-intervention assessment of their motor function and participation in life situations. Participants will receive physical therapy twice a week for 8 weeks for the intervention. In both groups, physiological, behavioral, and emotional responses to the interventions will be measured in 4 total sessions, 1 each at weeks 2, 4, 6, and 8.",[28],[61,62,63,64,65,66,67,68],"physical therapy","hippotherapy","pediatric","motor function","participation","upper extremity function","equine environment","neurmotor disorder","RECRUITING","2026-05-11",{"date":72,"type":39},"2026-05-14",{"date":74,"type":39},"2025-08-20",{"date":76,"type":22},"2027-04-30",{"name":78,"class":46},"University of Montana",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":47},"100624116","clinical-impacts-of-structured-robotic-gait-training-programs-100624116","NCT07405450","Clinical Impacts of Structured Robotic Gait Training Programs","Inclusion Criteria:\n\n* able to fit into Trexo robotic gait trainer (both leg length and weight); height of \\\u003C\\~5'6\", weight \\\u003C150 lbs.)\n* able to fulfill training requirements throughout training period\n* able to comply with study procedures (assessments, training)\n* any age\n\nExclusion Criteria:\n\n* those with contraindications to training with a robotic gait trainer (ie. medical condition or recent surgery requiring lower extremity immobilization or weight-bearing restriction (ie. fracture, unstable hip subluxation), medical condition requiring a physical activity restriction (ie. unstable arrythmia), pain or symptomatic hypotension while standing, contracture such that the Trexo Robotic Gait Training does not result in forward movement)\n* those involved in a potentially confounding intervention (will be discussed case-by-case to determine risk of impacting the study results).",{"count":86,"type":22},120,[25],"Background and Rationale:\n\nWalking impairments impacts the 2-3\u002F1000 children who have cerebral palsy1,2, and others unable to walk due to other central nervous system disorders such as a traumatic brain injury. The impacts of this and related impairment impact all aspects of life. The lifelong costs of these is staggering in terms of dollars (over $1 million\u002Fchild) and health adjusted life years (\\~half compared to typically developing populations despite only slightly shorter lifespans). Yet there are currently no effective interventions to treat the fundamental balance impairment that underlie these problems4,5. Early use of robotic gait trainers have shown many benefits6,7, however access to these trainers is limited due to cost, availability, and ease of use within the home. Currently, there are a few options for an overground robotic gait trainer supported by the stability of a walker. The Trexo, is an option designed for use at home or in a community settings, but barriers to access mean that access to this therapy is out of reach for many people who may see benefits.\n\nResearch Questions and Objectives:\n\nThe aim of this study is to (a) evaluate the feasibility of a clinical robotic gait training program and (b) evaluate the effectiveness of these types of programs in achieving patient, family, and therapist goals. The study will examine adherence to a structured training program to determine if training with a robotic gait trainer in a hospital setting is feasible for the entire length of the designed training program. Goals will be set, a re-evaluation of these goals will be completed following the training program to determine whether or not the clinical program of robotic gait training was successful in helping patients reach the goals set out at the beginning of the program.",[28,90],"Walking Impairment",[92,93],"Robotic Walking","Trexo","2026-02-10",{"date":96,"type":39},"2026-02-12",{"date":98,"type":39},"2022-11-01",{"date":100,"type":22},"2026-12",{"name":102,"class":46},"University of Calgary",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":47},"100310789","the-fbri-vtc-neuromotor-research-clinic-100310789","NCT03325946","The FBRI VTC Neuromotor Research Clinic","Inclusion Criteria:\n\n* Neuromotor Impairment\n\nExclusion Criteria:\n\n* fragile health","3 Months","18 Years",{"count":112,"type":22},500,"OBSERVATIONAL","The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr. Stephanie DeLuca and based on the principles surrounding ACQUIREc Therapy.\n\nACQUIREc Therapy is an evidenced-based approach to pediatric constraint-induced movement therapy, which refers to a multi-component form of therapy that is focused on helping children who have asymmetric motor abilities between the two sides of the body. Historically, ACQUIREc Therapy has the unimpaired or less impaired upper extremity constrained (by a cast or a splint) while also receiving active therapy from a specially trained therapist who shapes new skills and functional activities with the child's more impaired upper extremity but who is also a licensed Occupational or Physical Therapist (OT\u002FPT). Therapy dosages are high much higher than tradition OT or PT - often lasting many hours per day, up to 6 hours a day, 5 days a week, for 2-4 weeks.\n\nInvestigators have developed further treatments based on the same principles of intensive services combined with behavior shaping for other areas of the body that are also affected by weakness (e.g., the leg and trunk) also, but which usually do not involve constraint. These have been more generally labeled ACQUIRE Therapy.\n\nAll forms involve intensive, play-based therapy for children with asymmetric motor impairments of the arms and hands. The primary focus of treatment is to facilitate the acquisition of new motor skills in the child's weaker body parts through high levels of intensive therapy using scientifically-based behavioral guidelines. Therapy is also delivered in naturalistic environments.\n\nACQUIREc Therapy as a treatment method has been tested in two randomized controlled trials, and a specific manual for its implementation has been developed. Dr. (s) Ramey and DeLuca previously founded a similar clinic, The Pediatric Neuromotor Research Clinic, at the University of Alabama at Birmingham where Dr. DeLuca directed the research clinic for 13 years and oversaw the implementation of the ACQUIREc Therapy treatment protocol in more than 400 cases.\n\nThis research will involve analyzing and interpreting the clinical data of children going through clinical procedures at the FBRI VTC Neuromotor Research Clinic. All participation is voluntary and no children will denied services if families choose not to participate.",[28,116,117,118,119,120,121],"Cerebral Palsy","Microcephaly","Autism","Trauma, Brain","Acquired Brain Injury","Pediatric Stroke","2026-01-16",{"date":124,"type":39},"2026-01-21",{"date":126,"type":39},"2013-01-01",{"date":128,"type":22},"2029-12-31",{"name":130,"class":46},"Virginia Polytechnic Institute and State University",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":23,"phases":142,"briefSummary":143,"conditions":144,"keywords":145,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":160},"100567333","multicenter-study-that-offers-new-solutions-for-paediatric-rehabilitation-by-proposing-a-rehabilitation-plan-based-on-each-childs-needs-using-new-technological-and-robotic-devices-combined-among-them-100567333","NCT06666829","Multicenter Study That Offers New Solutions for Paediatric Rehabilitation by Proposing a Rehabilitation Plan Based on Each Child's Needs Using New Technological and Robotic Devices, Combined Among Them.","Innovative Paths to Paediatric Care: A Multicenter Study on the Efficacy of Multi-Domain Technological and Robotic Rehabilitation.","MultiTECHChild","Inclusion Criteria:\n\n* Confirmed diagnosis of developmental disorder and\u002For disability, either congenital or acquired;\n* Age between 5 and 21 years at the time of recruitment;\n* Verbal and\u002For non-verbal reasoning abilities \\> 70 or \\> 5th percentile, as assessed by standardized tests such as Colored Progressive Matrices (CPM), WISC-IV or WISC-V, WPPSI-III or WPPSI-IV, Leiter-3, Griffiths III.\n\nExclusion Criteria:\n\n* Presence of severe comorbidities and\u002For behavioral\u002Fcognitive disorders that prevent adequate patient compliance with both conventional and robotic rehabilitation treatment (severe intellectual disability);\n* Uncontrolled epilepsy;\n* Presence of severe sensory deficits;\n* Patients who have undergone orthopedic functional surgery or rhizotomy and\u002For botulinum toxin treatment in the last 6 months;\n* Involvement of the peripheral nervous system","21 Years",{"count":141,"type":22},194,[25],"The goal of this clinical trial is to demonstrate the efficacy of multi domain robotic and technological rehabilitation on everyday life and satisfaction in children with neuromotor conditions. The main questions it aims to answer are:\n\n* Will we have significant changes using the COPM in children taking part in the sperimental group?\n* The children who will undergo the multidomain treatment will also experience functional improvements in individual areas?\n* Thy type of treatment will improve motivation, active participation and satisfaction in children?\n\nResearcher will compare the multidomain treatment to standard care proposed by the included clinical centers: single domain rehabilitation with one innovative device. Both groups will undergo also conventional multidomain therapy.\n\nThis will be done to see if using a holistic approach, and including every need of the child in the rehabilitation plan, can lead to greater improvements in quality of life compared to the control group.\n\nParticipant will:\n\n* Be evaluated 3 times with clinical outcome measures\n* Take part in a rehabilitation program, at least 20 x 2hours sessions treatment, organized in:\n\n  * 4 weeks, 5 times per week\n  * 7 weeks, 3 times per week",[28],[146,147,148,149,150],"Children","Multidomain","Robotic rehabilitation","Technological rehabilitation","Innovative","2025-05-04",{"date":153,"type":39},"2025-05-07",{"date":155,"type":39},"2024-11-04",{"date":157,"type":22},"2027-01-31",{"name":159,"class":46},"IRCCS Fondazione Stella Maris",6]