[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuromuscular-block-residual\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuromuscular-block-residual":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100599428","quantitative-versus-qualitative-neuromonitoring-of-neuromuscular-block-for-non-cardiothoracic-surgery-100599428",false,"NCT07084363","Quantitative Versus qUAlitative NeuromoniToring of neUroMuscular Block for Non-cardiothoracic Surgery","Quantitative Versus qUAlitative NeuromoniToring of neUroMuscular Block for Non-cardiothoracic Surgery (The QUANTUM Trial): Single-center Cluster Randomized Multiple Crossover Trial","QUANTUM","Inclusion criteria:\n\n* Patient age ≥ 18 years old;\n* General anesthesia with endotracheal intubation;\n* Neuromuscular block with rocuronium.\n\nExclusion criteria:\n\n* Intubation before induction of anesthesia;\n* Critically ill patients admitted from the ICU;\n* Emergency cases;\n* Non-intubated patients;\n* Patients who will not be paralyzed through the surgery (spine).\n* Patients with an implanted electronic device (e.g. cardiac pacemaker)\n* Patients with allergies to adhesive\n* Patients with pre-existing neuromuscular disease (e.g. Myasthenia Gravis)","ALL","18 Years",{"count":20,"type":21},1032,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to assess the effect of quantitative block monitoring versus less expensive qualitative monitoring treatment effects on the lowest SpO2\u002FFiO2 ratio in the PACU. The results will be incorporated into an enhanced recovery pathway for surgical patients.",[27],"Neuromuscular Block, Residual","RECRUITING","2025-10-06",{"date":31,"type":32},"2025-10-10","ACTUAL",{"date":34,"type":32},"2025-09-22",{"date":36,"type":21},"2026-04-01",{"name":38,"class":39},"The University of Texas Health Science Center, Houston","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":40},"100607321","methylprednisolone-vs-dexamethasone-effects-on-sugammadex-reversal-pain-and-nausea-in-adults-100607321","NCT07187037","Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults","Comparison of the Effects of the Interaction of Methylprednisolone and Dexamethasone With Sugammadex on Rocuronium Reversal Time, Postoperative Pain, and Nausea in Adult Patients","Inclusion Criteria:\n\n* Adult patients aged 18-65 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled for elective septoplasty or rhinoplasty under general anesthesia\n* Written informed consent obtained\n\nExclusion Criteria:\n\n* ASA physical status ≥ III\n* Emergency surgery\n* Known allergy or contraindication to rocuronium, sugammadex, or corticosteroids\n* Chronic or recent (within 3 months) systemic corticosteroid therapy\n* Concomitant use of drugs that may interact with sugammadex (e.g., toremifene, flucloxacillin, fusidic acid)\n* Neuromuscular disorders (e.g., myasthenia gravis, muscular dystrophy)\n\n  * Significant hepatic, renal, respiratory, or cardiac dysfunction\n* Anticipated difficult airway or history of difficult intubation\n* Nasopharyngeal or oropharyngeal anomalies interfering with airway management\n* Developmental or cognitive impairment interfering with informed consent or cooperation",true,"65 Years",{"count":51,"type":21},130,[24],"This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty. The primary outcome is the time from sugammadex administration to recovery of a train-of-four (TOF) ratio of 0.9. Secondary outcomes include extubation time, postoperative nausea and vomiting (PONV), pain scores, complications in the post-anesthesia care unit (PACU), and intraoperative hemodynamic parameters. The study will provide new evidence on whether perioperative corticosteroid choice modifies the efficacy of sugammadex and influences postoperative recovery.",[27,55,56],"Pain","Postoperative Nausea",[58,59,60,61,62],"sugammadex","dexamethasone","methylprednisolone","postoperative nausea","postoperative pain","NOT_YET_RECRUITING","2025-09-18",{"date":34,"type":32},{"date":67,"type":21},"2025-10-01",{"date":69,"type":21},"2026-04-30",{"name":71,"class":39},"Konya City Hospital"]