[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuromuscular-control\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuromuscular-control":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,76,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100644543","comparative-effect-of-combined-strength-core-and-balance-training-on-kinesiophobia-ankle-instability-functional-outcomes-and-performance-in-table-tennis-players-with-functional-ankle-instability-100644543",false,"NCT07671170","Comparative Effect of Combined Strength, Core and Balance Training on Kinesiophobia, Ankle Instability, Functional Outcomes, and Performance in Table Tennis Players With Functional Ankle Instability","Inclusion Criteria:\n\n1. Male\u002Ffemale table tennis players aged 15-30 years\n2. Experienced at least one ankle sprain with swelling\u002Fpain that interrupted training for \\>1 day within the last 6 months\n3. Reported sensation of instability of the ankle\n4. Scored ≤25 points on the Cumberland Ankle Instability Tool (CAIT), indicating functional ankle instability\n\nExclusion Criteria:\n\n1. History of ankle fracture or surgery\n2. Any fracture of lower limb history\n3. Any neurological or vestibular disorders\n4. Other injuries of lower limb affecting performance",true,"ALL","15 Years","30 Years",{"count":20,"type":21},51,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial investigates the comparative effect of combined strength and balance training versus balance and core training on kinesiophobia (fear of movement), ankle instability, functional outcomes, and athletic performance in adolescent table tennis players with functional ankle instability (FAI). Participants will be randomly allocated into two groups over a 6-week intervention (3 sessions\u002Fweek). The Experimental Group will receive combined strength and balance training, while the Control Group will receive balance and core training. Outcomes will be measured using validated tools: TSK-17, CAIT, FAAM, Y-Balance Test, Single-Leg Hop Test, T-Test, and Illinois Agility Test.",[27,28,29,30],"Functional Ankle Instability","Kinesiophobia","Sports Rehabilitation","Neuromuscular Control",[32,33,27,34,35],"Balance Training","Athletes","Table Tennis","Strength Training","NOT_YET_RECRUITING","2026-06-22",{"date":39,"type":40},"2026-06-26","ACTUAL",{"date":42,"type":21},"2026-07",{"date":44,"type":21},"2026-10",{"name":46,"class":47},"Ibadat International University, Islamabad","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":15,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100637313","impact-of-neuromuscular-control-with-and-without-electrical-stimulation-and-long-term-effect-of-kinetic-chain-exercises-in-multidirectional-shoulder-instability-patients-100637313","NCT07611006","Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients","Inclusion Criteria:\n\n* Age: Between 20 and 50 years old.\n\nPatients with Multidirectional Shoulder Instability Must Meet the Following Conditions:\n\n(A) Generalized Joint Hypermobility: Beighton score ≥ 4\u002F9. (B) Shoulder Laxity Verified in at Least Two Directions During Clinical Examination (must meet A and B, or A and C): Inferior: Presence of a sulcus sign under the acromion or a positive Gagey hyperabduction test.\n\nAnterior: Positive anterior load and shift test or active shoulder external rotation \\> 85 degrees or passive shoulder external rotation \\> 90 degrees.\n\nPosterior: Positive posterior load and shift test or positive posterior jerk test.\n\n(C) Shoulder Pain for at Least Three Months Before the Start of the Study. (D) Signs of Shoulder Instability in Daily Life Without a Traumatic Cause. (E) Ability to Raise the Arm Above 120 Degrees Without Experiencing Subluxation or Dislocation of the Shoulder.\n\nExclusion Criteria:\n\n* Shoulder pain caused by trauma. History of shoulder fractures or dislocations. Cervical radiculopathy. Degenerative joint disease of the shoulder. Previous shoulder surgery. Frozen shoulder. Pain score greater than 5 during experimental movements. Redness, swelling, or open wounds on the skin within the experimental area. Sensory abnormalities. Cognitive impairment.","20 Years","50 Years",{"count":57,"type":21},60,[24],"Background: Shoulder instability is commonly observed in adolescents and young females, ranging from asymptomatic multidirectional instability (MDI) to symptomatic conditions. Patients with MDI often experience shoulder pain, muscle tension, and episodes of subluxation. This condition is associated with hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS), both characterized by generalized joint laxity and recurrent joint dislocations, significantly affecting daily activities and athletic performance. Current literature lacks clarity on the actual humeral head displacement, shoulder joint kinetics, and muscle activity characteristics during movement in patients with MDI accompanied by HSD or hEDS. Additionally, the effects of electrical stimulation on different shoulder muscles and its impact on humeral head displacement in MDI patients remain to be validated.\n\nObjective: The purposes of this study are to (1) examine whether patients with hEDS\u002FHSD and MDI have increased humeral head translation compared to healthy controls during three isometric contraction ; (2) investigate the relationship between humeral head translation and associated muscle activity during three isometric exercises ; (3) examine the effect of NMES and NMCT to humerus\u002Fscapula muscles on humeral head translations in MDI patients with hEDS\u002FHSD Outcome measurements: The primary outcomes include changes in acromiohumeral distance (AHD) or humeroglenoid distance (HGD) under four conditions (no stimulation, NMCT, BLH\u002FInfraspinatus\u002FMD stimulation, and SA stimulation) during three isometric contractions (shoulder flexion, horizontal adduction, and fully extended elbow holding weight).\n\nThe secondary outcomes assess muscle activation differences in BLH, infraspinatus, MD, UT, LT, and SA before and after NMCT.",[61,62,63,30,64],"Multidirectional Instability","Hypermobility Spectrum Disorder","Electrical Stimulation","Humeral Head Translation","RECRUITING","2026-05-20",{"date":68,"type":40},"2026-05-28",{"date":70,"type":40},"2025-11-09",{"date":72,"type":21},"2026-07-30",{"name":74,"class":47},"National Taiwan University Hospital",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":15,"sex":16,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":75},"100637817","structured-neuromuscular-exercise-program-100637817","NCT07596420","Structured Neuromuscular Exercise Program","The Effect of s Structured Neuromuscular Exercise Program on Running Performance and Lower Extremity Biomechanics in Recreational Runners","nmep-run","Inclusion Criteria:\n\n* Age between 18 and 55 years\n\nRecreational runners who have been running regularly (at least twice per week for the last 6 months)\n\nNo current musculoskeletal injury limiting running\n\nWilling to participate in the 8-week neuromuscular exercise program and attend follow-up assessments\n\nAble to provide informed consent\n\nExclusion Criteria:\n\n* History of lower limb surgery or fracture in the past 6 months\n\nNeurological, vestibular, or systemic diseases affecting balance or gait\n\nCurrent participation in a structured strength or neuromuscular training program\n\nPregnancy","18 Years","55 Years",{"count":87,"type":21},24,[24],"This randomized controlled trial aims to investigate the effects of an 8-week structured neuromuscular exercise program on running performance and lower extremity biomechanics in recreational runners. The program includes progressive exercises focusing on hip and core strength, balance, plyometric control, and running-specific mobility. Participants will be randomly assigned to an intervention or control group. The intervention group will perform the neuromuscular training twice a week for eight weeks, while the control group will not receive any structured exercise. Pre- and post-intervention assessments will include biomechanical analysis and functional performance tests. The study aims to provide evidence for the preventive and performance-enhancing benefits of neuromuscular training in runners.",[91,30,92,93],"Running Biomechanics","Running-Related Injury Prevention","Recreational Runners",[95,96,97,98,99,100,101],"Neuromuscular Exercise","Performance, Balance","Core Strength","Hip Stability","Lower Limb Biomechanics","Injury Prevention","Running Training","2026-05-12",{"date":104,"type":40},"2026-05-19",{"date":106,"type":21},"2026-05",{"date":108,"type":21},"2026-09",{"name":110,"class":47},"Elif Tunç",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":16,"minAge":84,"maxAge":18,"enrollmentInfo":118,"targetDuration":4,"studyType":22,"phases":120,"briefSummary":121,"conditions":122,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":75},"100600406","study-of-functional-magnetic-resonance-signal-variations-in-patients-undergoing-anterior-cruciate-ligament-reconstruction-with-the-application-of-a-dedicated-neuromotor-training-100600406","NCT07097077","Study of Functional Magnetic Resonance Signal Variations in Patients Undergoing Anterior Cruciate Ligament Reconstruction With the Application of a Dedicated Neuromotor Training","ACL-fMRI-TNMT","Inclusion Criteria:\n\n* Patients who have undergone anterior cruciate ligament reconstruction surgery at any healthcare facility\n* Able to understand and consent, adults, who have provided informed consent to participate in the study\n* Male or female\n* Age between 18 and 30 years at the time of signing the informed consent\n* Tegner activity level \\> 6\n\nExclusion Criteria:\n\n* History and\u002For evidence of any neurological disorder or functional impairment;\n* Evidence of previous surgeries on the lower limb;\n* Inability to provide informed consent;\n* Inability to perform the tasks required by the procedure;\n* Pregnant or breastfeeding women;\n* Oncology patients;\n* Contraindications to undergoing MRI examinations.",{"count":119,"type":21},12,[24],"Lower limb injuries represent the majority of sports-related injuries, with knee injuries being among the most common. In particular, anterior cruciate ligament (ACL) injuries are considered highly devastating and career-threatening for both professional and amateur athletes. Current surgical and rehabilitation treatments often fail to provide fully satisfactory short- and long-term outcomes. A very high risk of re-injury exists, especially in younger patients, with up to 35% experiencing a second ACL injury, alongside a significant long-term risk of early knee osteoarthritis.\n\nMost ACL injuries are non-contact or indirect contact injuries, implicating biomechanical factors and neuromuscular control as key determinants of injury mechanisms. Recent literature shows that patients suffering a non-contact ACL injury have a higher risk of re-injury compared to those with contact injuries, suggesting a significant cognitive component in injury processing, surgery, rehabilitation, and return to sport.\n\nRecent rehabilitation studies have introduced targeted neuromotor training designed to \"rebuild\" biomechanical and neuromuscular patterns to avoid mechanisms leading to re-injury. Movement quality tests are used post-training to confirm the reduction of risky biomechanical patterns, often resulting in a score indicating movement quality.\n\nGiven the brain's involvement in such injuries, pioneering studies have used functional magnetic resonance imaging (fMRI) to investigate changes in cortical brain areas following ACL injury and reconstruction. Evidence shows adaptations in both central and peripheral nervous systems, with altered sensorimotor cortex activation in patients during simple motor tasks, differing from healthy subjects. Prefrontal cortex alterations correlate with severe quadriceps muscle activation asymmetries, linking these brain patterns to post-injury return-to-sport outcomes.\n\nHowever, no studies have yet evaluated the interaction between cortical activation (neural compensations) measured by fMRI and outcomes from targeted neuromotor training during ACL rehabilitation. Understanding brain activation implications is crucial for developing large-scale rehabilitation protocols to reduce the risk of a second, potentially more devastating, knee injury.\n\nThis study aims to reveal whether a neuromotor training protocol can positively influence cognitive brain areas related to human movement, particularly by reducing risky injury patterns. It will be the first to test whether dedicated neuromuscular training effectively reduces neural compensations and cortical activation related to non-automated movement, favoring automation areas important for a safe return to sport.\n\nPatients will directly benefit from participating in the innovative neuromotor training program, with functional MRI scans conducted before training begins (post-surgery) and after training completion. Indirectly, the study will assess whether neuromotor training can adapt patient neuromotor patterns to reduce re-injury risk, ultimately benefiting future patients undergoing ACL reconstruction.",[123,124,125,30],"fMRI","ACL Injury","Rehabilitation Exercise","2026-02-25",{"date":128,"type":40},"2026-02-27",{"date":130,"type":40},"2026-02-07",{"date":132,"type":21},"2027-07",{"name":134,"class":47},"Stefano Zaffagnini"]