[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuromuscular-scoliosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuromuscular-scoliosis":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,49,80,112,139,165,198,226],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100519373","kids-with-iron-deficiency-and-scoliosis-100519373",false,"NCT06042699","Kids With Iron Deficiency and Scoliosis","Kids With Iron Deficiency and Scoliosis (KIDS) Study","KIDS","Inclusion Criteria:\n\n1. 10-26 years old;\n2. diagnosis of scoliosis or kyphosis;\n3. self-reported ability to swallow a tablet;\n4. spinal fusion procedure planned approximately 6 to 24 weeks from an orthopedic surgical clinic visit at which patient agrees to phlebotomy for screening blood work;\n5. serum ferritin less than or equal to 25 µg\u002FL.\n\nExclusion Criteria:\n\n1. taking or planning to take iron-containing supplement on patient's own volition, and not willing to stop for duration of study;\n2. taking or planning to take iron-containing supplement as prescribed or recommended under the care of a physician;\n3. Hg \\\u003C10mg\u002FdL if post-menarchal, Hg \\\u003C 11 if premenarchal or male\n4. C-reactive protein \\> 10 mg\u002FL\n5. receiving nutritional support by report in the medical chart;\n6. self-reported history of hypersensitivity reaction to iron-containing supplements;\n7. self-reported history of or suspected non-iron deficient hematologic disorder;\n8. self-reported history of iron overloaded state such as hereditary hemochromatosis or hemosiderosis;\n9. objection to receiving red blood cell transfusions;\n10. current pregnancy (by self-report);\n11. prisoners;\n12. patient or parent decides against study participation.",true,"ALL","10 Years","26 Years",{"count":22,"type":23},275,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and diminished postoperative cognitive and physical capacity in adolescents undergoing scoliosis surgery.\n\nResearch Question(s)\u002FHypothesis(es):\n\nPrimary\n\n* Iron supplementation will reduce the incidence of perioperative RBC transfusion in iron deficient scoliosis patients undergoing spinal fusion.\n\nSecondary\n\n* Iron supplementation will reduce postoperative neurocognitive functional declines in iron deficient scoliosis patients undergoing spinal fusion.\n* Iron supplementation will improve patient-reported physical functioning in iron deficient scoliosis patients undergoing spinal fusion.",[29,30,31,32,33,34,35],"Adolescent Idiopathic Scoliosis","Neuromuscular Scoliosis","Perioperative\u002FPostoperative Complications","Iron Deficiencies","Anemia","Spinal Fusion","Postoperative Cognitive Dysfunction","RECRUITING","2026-06-25",{"date":39,"type":40},"2026-06-26","ACTUAL",{"date":42,"type":40},"2024-01-11",{"date":44,"type":23},"2028-02-01",{"name":46,"class":47},"Columbia University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":48},"100643611","understanding-the-causes-of-idiopathic-scoliosis-through-the-longitudinal-analysis-of-proteomic-markers-the-uncoil-study-100643611","NCT07634627","UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study","UNCOIL","Inclusion Criteria:\n\n* Patients 10-17 years old with idiopathic or neuromuscular scoliosis with a cobb angle of 10-50° that are currently being seen for their scoliosis at a Children's Hospital Colorado location\n\nExclusion Criteria:\n\n* Children diagnosed with certain genetic conditions that affect the bones or muscles (Turner syndrome, down syndrome, Marfan syndrome, osteogenesis imperfecta, muscular dystrophy, Ehlers-Danlos syndrome, VATER\u002FVACTERL syndrome, Rett syndrome, Prader Willi syndrome, or Angelman syndrome)\n* Patients with congenital scoliosis, early onset scoliosis (diagnosed before 9 years old), or those who have spine surgery scheduled prior to the first study visit\n* Patients whose spinal curve is \\>50 degrees\n* Those taking medications that may influence protein expression (baclofen, prednisone\u002Fcorticosteroids, antiepileptic medications, diazepam, tizanidine, and\u002For dantrolene)\n* Patients who are pregnant\n* Patients with neurocognitive disorders who are non-verbal and\u002For non-ambulatory\n* Patients who are not receiving care for scoliosis at a Children's Hospital Colorado location","17 Years",{"count":58,"type":23},500,"OBSERVATIONAL","The goal of this observational study is to find clinical, demographic, and protein biomarkers that scoliosis progression (scoliosis curve increases) and\u002For differ between participants with scoliosis versus those without scoliosis. The investigators aim to answer the following questions:\n\n1. Are age, sex, skeletal maturity, and family history associated with scoliosis curve progression?\n2. Do protein levels differ between progressive and non-progressive cases?\n3. Do protein levels change between baseline and follow-up visits in progressive and non-progressive scoliosis cases?\n4. Do proteins differ between participants with AIS vs those without AIS?\n5. Do proteins or change in proteins differ between participants with AIS vs those with scoliosis secondary to neuromuscular conditions.\n\nParticipants will:\n\n* Participate in two research visits 6-12 months apart at a Children's Hospital Colorado location.\n* Participate in a blood draw at each study visit to collect about 3 tablespoons of blood.\n* Fill out surveys yearly regarding new medical visits, pain, physical function, anxiety and depression, medical and family history, and current medications.",[62,30],"Adolescent Idiopathic Scoliosis (AIS)",[29,64,65,66,67,68,69,70],"Proteomics","AIS","Idiopathic Scoliosis","protein biomarkers","biomarkers","plasma proteomics","Neuromuscular scoliosis","2026-06-18",{"date":73,"type":40},"2026-06-23",{"date":75,"type":40},"2024-12-05",{"date":77,"type":23},"2031-12",{"name":79,"class":47},"University of Colorado, Denver",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":17,"sex":18,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":91,"studyType":59,"phases":4,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":109,"locationsCount":111},"100444723","advanced-spinal-innovations-with-robotics-and-enabling-technology-registry-100444723","NCT05071144","Advanced SPinal Innovations With Robotics and Enabling Technology Registry","ASPIRE","Inclusion Criteria:\n\n* Diagnosis of a spine deformity\n* Scheduled for surgery using robotics and navigation and\u002For patient-specific rods\n* Up to and including 21 years of age\n* Speak and read English or Spanish\n\nExclusion Criteria:\n\n• None","0 Years","21 Years",{"count":90,"type":23},700,"5 Years","Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation, as well as patient-specific rods in pediatric spine deformity surgery across participating study institutions. Eventually, an educational and informative framework for this technology will be established.",[94,66,29,95,96,30],"Spine Deformity","Spondylolisthesis","Congenital Scoliosis",[98,99,100,101,102,103],"Pediatric","Spine","Surgery","Registry","Robotic","Navigation",{"date":105,"type":40},"2026-06-22",{"date":107,"type":40},"2021-12-13",{"date":77,"type":23},{"name":110,"class":47},"Boston Children's Hospital",10,{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":122,"conditions":123,"keywords":126,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":138},"100460909","post-market-clinical-follow-up-study-on-the-safety-and-performance-of-ennovate-complex-100460909","NCT05281757","Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex","Multicenter Post Market Clinical Follow-Up (PMCF) Study on the Safety and Performance of Ennovate® Complex - A Prospective Study on Scoliosis Patients","COSINE","Inclusion Criteria:\n\n* Informed consent in the documentation of clinical and radiological results of patients who are minimum 18 years old\n* Informed consent in the documentation of clinical and radiological results of patients AND legal representative (parent) for patients who are younger than 18\n* Patient's indication according to IFU\n* Patient is not pregnant\n\nExclusion Criteria:\n\n* Patient's clear unability or unwillingness to participate in follow-up examinations",{"count":121,"type":23},200,"Multicenter, multinational Post-Market Clinical Follow-Up (PMCF) study on the safety and performance of Ennovate® Complex - A prospective, pure data collection of all Ennovate® scoliosis patients in selected centers (not interventional, multicentric)",[124,125,96,30,66],"Hyperkyphosis","Hyperlordosis",[127],"upper-thoracic spine","2026-06-01",{"date":130,"type":40},"2026-06-02",{"date":132,"type":40},"2022-02-18",{"date":134,"type":23},"2028-10",{"name":136,"class":137},"Aesculap AG","INDUSTRY",2,{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":24,"phases":149,"briefSummary":151,"conditions":152,"keywords":153,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":48},"100636141","phase-3-the-effect-of-erector-spinae-plane-block-espb-on-pediatric-pain-management-following-posterior-spinal-fusion-psf-surgery-100636141","NCT07561827","The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery","ESPB","Inclusion Criteria:\n\n* Diagnosis of Adolescent Idiopathic Scoliosis (AIS) or neuromuscular scoliosis\n* Undergoing Posterior Spinal Fusion (PSF) Surgery\n\nExclusion Criteria:\n\n* Patients with forms of scoliosis other than AIS or NM Scoliosis.\n* Patients undergoing a spinal deformity correction surgery other than Posterior Spinal Fusion Surgery\n* Allergy or other contraindication to erector spinae plane block (ESPB) with Ropivacaine patients who are taking pre-operative opioids","18 Years",{"count":148,"type":23},42,[150],"PHASE3","This study is being done to better understand the efficacy of an erector spinae plane block (ESPB) in pain management for children with Adolescent Idiopathic Scoliosis or Neuromuscular Scoliosis undergoing Posterior Spinal Fusion surgery. The study team is trying to find out if receiving the ESPB leads to less pain and less need for pain medication after surgery.\n\nThe ESPB involves an injection of a local anesthetic, ropivacaine, into your child's back muscles to help block pain signals.",[62,30,29],[154,155],"posterior spinal fusion","pain management","2026-04-24",{"date":158,"type":40},"2026-05-01",{"date":160,"type":40},"2025-06-06",{"date":162,"type":23},"2027-01-26",{"name":164,"class":47},"University of California, San Francisco",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":18,"minAge":172,"maxAge":4,"enrollmentInfo":173,"targetDuration":4,"studyType":24,"phases":175,"briefSummary":176,"conditions":177,"keywords":183,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":138},"100605853","developing-an-innovative-decision-support-tool-for-pediatric-neuromuscular-scoliosis-100605853","NCT07167927","Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis","Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis - Aims 2 and 3","Inclusion criteria:\n\n* Parent-child dyads of children with neuromuscular scoliosis who speak English and Spanish.\n* Child is between ages 8-21 years of age and they are coming into the pediatric orthopaedic surgery clinic for consultation about potential surgery for NMS.\n* NMS is defined as having neurologic impairment (NI) and scoliosis using relevant ICD-9 or ICD-10 codes from Feudtner, et al. 2014 or Berry, et al. 2012. or a qualifying diagnosis per the Pediatric Spine Study Group definition of NMS.\n* All pediatric orthopaedic surgeons and neurosurgeons who treat neuromuscular scoliosis at our study sites will be eligible participants.\n\nExclusion criteria:\n\n* Families whose child with NMS is less than 8 years of age at time of orthopaedic consultation because surgery at a younger age usually indicates an atypical case.\n* Children with the diagnosis of Duchenne's or Becker's muscular dystrophy due to potential disease modifying therapies that may alter curve progression.","8 Years",{"count":174,"type":23},110,[26],"The goal of this pilot hybrid type I efficacy\u002Fimplementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis (NMS). Results from this pilot will inform the design of a future larger effectiveness trial of the decision support tool.\n\nParticipants will either receive usual care or receive the decision support tool. Researchers will assess the decision made, decision quality, individual affective, cognitive, and behavioral effects, and feasibility and acceptability of tool use. They will also collect potential barriers and facilitators to implementation and feedback about the tool and study design to maximize likelihood of successful deployment of the tool into clinical practice and inform the design of a future trial. The outcomes measures will be used to inform potential effect size estimates to inform a future trial.",[178,179,30,180,181,182],"Children With Medical Complexity (CMC)","Multiple Chronic Conditions","Shared Decision Making","Decision Support Systems, Clinical","Decision Aids",[184,185,186,187,188],"children with medical complexity","shared decision making","values clarification","uncertainty communication","decision support tool","2025-12-04",{"date":191,"type":40},"2025-12-05",{"date":193,"type":40},"2025-10-21",{"date":195,"type":23},"2027-03-31",{"name":197,"class":47},"University of Utah",{"id":199,"slug":200,"hasResults":11,"nctId":201,"briefTitle":202,"officialTitle":203,"acronym":204,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":88,"enrollmentInfo":206,"targetDuration":4,"studyType":24,"phases":208,"briefSummary":209,"conditions":210,"keywords":211,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":221,"leadSponsor":223,"locationsCount":138},"100587891","phase-3-pooled-human-plasma-vs-crystalloid-in-the-management-of-children-undergoing-instrumented-spinal-fusion-for-scoliosis-100587891","NCT06934278","Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis","Pooled Human Plasma vs Crystalloid in The Management of Children Undergoing Instrumented Spinal Fusion for Scoliosis: A Double-Blind, Randomized Clinical Trial","OCTAGON","Inclusion Criteria:\n\n* Written informed consent.\n* Aged between 10 and 21 years of age\n* Scoliosis requiring posterior scoliosis surgery using all pedicle screw technique for AIS (\\>45-degree major curve) or NMS (\\>50-degree major curve)\n* Normal whole spine MRI except for the spinal deformity (only for patients with adolescent idiopathic scoliosis as patients with neuromuscular scoliosis do not typically undergo MR images as they would need general anaesthesia)\n\nExclusion Criteria:\n\n* Immunoglobulin A-deficiency\n* Need for anteroposterior surgery\n* Need for three column vertebral resection\n* Smoking\n* Diabetes mellitus\n* Abnormalities in blood coagulation (thromboplastin time below above or below of normal values, 70-130%)\n* Blood trombosytes less than 150 x E9\u002Fl\n* Body mass index over 40\n* Allergy or hypersensitivity to study medications or their ingredients\n* Pregnancy or breast-feeding, aim of becoming pregnant during the study.\n* Participation in another study and receipt of any other investigational agent during 2 year period of current investigation\n* Inability to provide written informed consent\n* Any significant disease or disorder which, in the opinion of the investigator, may either put the subject at risk by participation in the study, or may influence the result of the study.\n* A history of drug or alcohol use that, in the opinion of the investigator, would interfere with adherence to study requirements.\n* Known history of, or documented positive hepatitis B or C or HIV infection Prior or concurrent malignancy\n* Aspartate transaminase (AST) or alanine transaminase (ALT) ≥ 3 x upper-limit of normal\n* Creatinine clearance (CrCl) \\\u003C 60 ml\u002Fmin measured by 24-hour urine collection or estimated from the Cockcroft and Gault formula\n* Clinically significant ECG findings as judged by the investigator\n* Amiodarone medication\n* Hyperkalemia\n* Renal insufficiency\n* AV-block\n* Metabolic or respiratory alkalosis\n* Hypochlorhydria\n* Hypersensitivity for active component or additives.",{"count":207,"type":23},194,[150],"OCTAGON trial is a randomized, double-blinded, parallel-group non-inferiority multicenter (Helsinki and Turku University Hospitals, Finland) clinical trial according to CONSORT criteria.\n\n194 adolescents with idiopathic (major curve \\> 45 degrees) or neuromuscular scoliosis (major curve \\> 50 degrees) are enrolled for the OCTAGON trial comparing pooled human plasma (Octaplas, 10mL\u002Fkg, active management) vs. Plasmalyte (10 mL\u002Fkg, placebo) before incision as part of the normal intraoperative fluid therapy. Data is collected at baseline and at each follow-up until a minimum of 2-year follow-up.\n\nOutcomes Outcomes for the OCTAGON trial include 1) intraoperative blood loss (in mL, primary outcome) and the need for allogenic red blood cell infusion (percentage of patients). Secondary outcomes include health-related quality of life (Scoliosis Research Society 24 outcome questionnaire), postoperative pain (48-hour opioid consumption), operative time (hours), drain output (mL), hidden blood loss (mL), hospital stay, and complications (skin reactions, TRALI, deep surgical site infection, neurologic deficit).\n\nResearch questions and hypothesis Does prophylactic use of pooled human plasma decrease intraoperative blood loss in adolescents undergoing instrumented spinal fusion for scoliosis? We hypothesize that pooled human plasma will reduce intraoperative and total blood loss by 25% resulting in lower need for blood transfusion and fewer surgical site infections.\n\nObjectives To compare the effect of pooled human plasma vs. crystalloid fluids on intraoperative bleeding and total blood loss (drain output and hidden blood loss) in children undergoing posterior spinal fusion for AIS and NMS. Adverse events will be recorded and reported as minor (skin reaction) or major (severe allergic reaction, transfusion related acute lung injury, TRALI, deep surgical site infection, neurologic injury).\n\nEthical aspects The PHP trial has been evaluated via European regulatory authority (EU CT: 2024-514857-31-00) and by Fimea (FIMEA\u002F2024\u002F006588). Informed consent is obtained from the parent(s). Results will be disseminated in high-quality peer-reviewed publications.\n\nThe individual patient safety and high-quality management of fractures and scoliosis is a priority in this trial. The randomization can be opened at any stage of the treatment process. Based on the clinical decision the randomized treatment can be terminated and treatment provided accord-ing to clinical decision making even if results will be evaluated using the intention to treat princi-ple. Pain management will be prioritized in every clinical scenario and parental presence is always possible.",[62,30],[212,213,214,215,216],"adolescent idiopathic scoliosis","neuromuscular scoliosis","pooled human plasma","randomized clinical trial","double-blind placebo controlled","2025-05-02",{"date":219,"type":40},"2025-05-07",{"date":217,"type":40},{"date":222,"type":23},"2030-12-31",{"name":224,"class":225},"Turku University Hospital","OTHER_GOV",{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":18,"minAge":233,"maxAge":146,"enrollmentInfo":234,"targetDuration":4,"studyType":24,"phases":236,"briefSummary":238,"conditions":239,"keywords":240,"overallStatus":244,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":48},"100517861","phase-4-postoperative-steroid-use-in-adolescent-idiopathic-scoliosis-and-neuromuscular-scoliosis-patients-100517861","NCT06023043","Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients","A Randomized Trial of Postoperative Steroid Use Following Posterior Spinal Fusion in 100-subject Adolescent Idiopathic Scoliosis (AIS) and Neuromuscular Scoliosis (NMS)","Inclusion Criteria:\n\nParticipants must meet all of the inclusion criteria to participate in this study:\n\n• Patients aged 9-18 years who are scheduled to undergo posterior spinal fusion to treat AIS or NMS\n\nExclusion Criteria:\n\nPatients will be excluded if any of the following criteria are met at baseline:\n\n* Prior instrumentation or spine surgery\n* Conditions associated with increased wound healing issues such as spina bifida\n* Non AIS or NMS patients\n* Not undergoing PSF\n* Outside the ages of 9-18\n* Allergies to the steroids and\u002For their ingredients\n* Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements\n* Inability or unwillingness of individual or legal guardian\u002Frepresentative to give written informed consent.","9 Years",{"count":235,"type":23},100,[237],"PHASE4","The goal of this randomized clinical trial is to compare the immediate use of steroids after surgery for accelerated discharge in adolescent idiopathic scoliosis and neuromuscular scoliosis after a posterior spinal fusion.\n\nThe main question it aims to answer are:\n\n* What are the effects of using steroids immediately after surgery in decreasing opioid use and helping early mobilization(movement)?\n* Does post-operative steroid use affect the incidence of wound complications and are there any long-term impacts on scar formation?\n\nParticipants will:\n\n* Fill out a Patient-Reported Outcomes Measurement Information System (PROMIS) survey specifically for pain interference and physical activity observing health related quality of life at enrollment, 3 months, 1 year, and 2 years\n* Have clinical photos of their incision at 3 months, 1 year, and 2 years\n\n  * Their photos will be assessed using the stony book scar evaluation scale\n* For treatment of their scoliosis, patients will undergo a posterior spinal fusion (PSF) per standard of care, however whether the participant receives or does not receive steroids is what the investigators are trying to understand.\n* Researchers will compare no immediate postoperative steroid (NS) to the group with immediate postoperative steroid (WS) group to see if there are changes in opioid use, wound complications, scar formation, and facilitation in early mobilization.",[30,29],[241,242,243],"Steroid","Dexamethasone","Scoliosis","NOT_YET_RECRUITING","2025-03-03",{"date":247,"type":40},"2025-03-05",{"date":249,"type":23},"2025-11-01",{"date":251,"type":23},"2028-12-31",{"name":253,"class":47},"Children's Hospital Los Angeles"]