[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuropathic-pain-diagnostic-questionnaire-dn4--4\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuropathic-pain-diagnostic-questionnaire-dn4--4":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100638006","hematological-indices-and-sympathetic-block-response-in-neuropathic-pain-100638006",false,"NCT07596823","Hematological Indices and Sympathetic Block Response in Neuropathic Pain","Hematological Inflammatory Indices as Predictors of Treatment Response to Sympathetic Nerve Blocks in Neuropathic Pain: A Prospective Observational Study","HINSPAIN","Inclusion Criteria:\n\n* Age ≥18 years\n* Diagnosis of neuropathic pain based on clinical evaluation\n* DN4 and\u002For LANSS scores compatible with neuropathic pain\n* Undergoing sympathetic nerve block as part of routine clinical treatment\n* Availability of pre-treatment and follow-up hemogram parameters\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Active infection or acute inflammatory disease\n* Active malignancy\n* History of hematological disease\n* Immunosuppressive therapy or systemic corticosteroid use\n* Major surgery or severe trauma within the last month\n* Pregnancy or breastfeeding\n* Autoimmune or rheumatologic inflammatory disease\n* Missing follow-up data","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","3 Months","OBSERVATIONAL","This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as part of routine clinical care. Hematological parameters including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), aggregate index of systemic inflammation (AISI), and red cell distribution width (RDW) will be evaluated before and after treatment. The association between changes in these indices and pain outcomes will be analyzed.",[26,27],"Neuropathic Pain","Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4",[26,29,30],"Sympathetic Nerve","Inflammation","RECRUITING","2026-06-25",{"date":34,"type":35},"2026-06-29","ACTUAL",{"date":37,"type":21},"2026-06-01",{"date":39,"type":21},"2027-01-31",{"name":41,"class":42},"Ankara City Hospital Bilkent","OTHER"]