[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neutrophil-mediated-inflammatory-dermatoses\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neutrophil-mediated-inflammatory-dermatoses":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100495575","genetic-architecture-of-neutrophil-mediated-inflammatory-skin-diseases-100495575",false,"NCT05732987","Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases","Case-Control Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases","NEUTROSKIN","Inclusion Criteria:\n\n* written consent of the participating person\n* diagnosis of a disease in the NMID form group or proband of the control group\n\nExclusion Criteria for patients:\n\n* Missing informed consent if samples collected after 2014\n* no diagnosis of NMID\n\nExclusion Criteria for healthy controls:\n\n* Missing informed consent",true,"ALL","18 Years","100 Years",{"count":22,"type":23},3370,"ESTIMATED","OBSERVATIONAL","This study is to identify rare, disease-causing mutations of several rare neutrophil dermatoses. To identify associations between NMID and variants in the genome next generation sequencing, mainly whole exome sequencing, will be used. In a second approach the expression level of already known inflammatory proteins in skin samples will be investigated.",[27,28],"Neutrophil-mediated Inflammatory Dermatoses","Inflammatory Dermatoses",[30,31,32,33],"inflammasome","inflammation-driving pathway","gene variants","next generation sequencing","RECRUITING","2023-08-21",{"date":37,"type":38},"2023-08-22","ACTUAL",{"date":40,"type":38},"2023-02-03",{"date":42,"type":23},"2029-09",{"name":44,"class":45},"University Hospital, Basel, Switzerland","OTHER"]