[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"night-shift-work\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:night-shift-work":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100643653","shift-workers-health-behavior-action-program-across-europe-100643653",false,"NCT07631767","Shift Workers' Health Behavior Action Program Across Europe","SHAPE","Inclusion Criteria:\n\n* Age ≥ 21 years\n* Work ≥ 24 hours per week\n* Shift work duration \\> 3 years and currently doing night shifts\n* Expected to continue night shiftwork for at least 1 year after inclusion\n* On average working ≥ 4 night shifts per month\n* Working generally ≥ 2 consecutive night shifts\n* In possession of a smartphone and willing to download the study application\n\nExclusion Criteria:\n\n* Body Mass Index (BMI) \\\u003C 18.5 or \\> 40 kg\u002Fm2\n* Pregnant or lactating\n* Chronic diseases with ongoing therapy (e.g. renal failure, active hepatitis, cirrhosis, myocardial infarction, chronic obstructive pulmonary disease and cancer)\n* Current or recent use of medications interfering with sleep, including: Central nervous system stimulants (e.g., Ritalin, Adderall, Modafinil or similar); Chronic use of sleep agents (e.g., benzodiazepine, non-hypnotic benzodiaze-pine, first-generation antihistamine, melatonin receptors agonists or similar); Other medications or combinations significantly affecting sleeping patterns\n* Recent or ongoing psychotherapy for sleep disorders\n* Current or recent use of medications affecting appetite or weight regulation, including: Appetite-enhancing\u002Fweight-gain medications (e.g., atypical antipsychotics, cor-ticosteroids such as prednisone, mirtazapine or similar); Appetite-suppressing\u002Fweight-loss medications (e.g., CNS stimulants such as Ritalin, Adderall, GLP-1 receptors agonists or similar); Other medications or combinations significantly influencing appetite or body weight\n* Participation in another human trial, lifestyle program or weight loss intervention within the past 3 months\n* Planned surgical procedure during the study period\n* History of or planned bariatric surgery\u002Ftreatment",true,"ALL","21 Years",{"count":20,"type":21},400,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates the effects of a Combined Lifestyle Intervention Program (CLIP) on sleep, lifestyle behaviors, obesity risk and health in night-shift workers. The primary objective is to assess the effect of the CLIP on objectively measured sleep duration. Secondary objectives include behavioral outcomes related to sleep, diet, physical activity, and stress, as well as body weight and metabolic outcomes, . It is hypothesized that CLIP participants will show a greater increase in sleep duration than controls, alongside favorable changes in lifestyle and health outcomes.",[27,28,29],"Night Shift Work","Obesity & Overweight","Circadian Misalignment",[31,32,33,34,35],"Lifestyle","Stress","Sleep","Diet","Physical Activity","NOT_YET_RECRUITING","2026-06-01",{"date":39,"type":40},"2026-06-08","ACTUAL",{"date":42,"type":21},"2026-05-15",{"date":44,"type":21},"2027-12-01",{"name":46,"class":47},"Wageningen University","OTHER",5,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100624457","association-between-slow-wave-activity-and-sleep-inertia-100624457","NCT07409883","Association Between Slow Wave Activity and Sleep Inertia","Association Between Slow Wave Activity and Sleep Inertia in Nighttime Simulated Naps: An Observational Study With Nap Intervention","Inclusion Criteria:\n\n1. Age between 18 and 60 years\n2. History of appropriate sleep duration at least 6 hours\u002Fnight for a minimum of 2 weeks assessed by sleep diary before the trial\n\nExclusion Criteria:\n\n1. STOP-BANG ≥3 or previous diagnosis of obstructive sleep apnea\n2. Presence of restless legs syndrome as assessed with IRLSSG criteria\n3. Presence of depression as assessed by HADS (Exclude participants with HADS-Depression sub-scale score ≥8 (possible depression)\n4. History of irregular work hours or shift work within 2 weeks\n5. Use of sedative\u002Fhypnotic medications on a regular-basis (3 days\u002Fweek or above)\n6. History of epilepsy and brain tumor","18 Years","80 Years",{"count":59,"type":21},28,"OBSERVATIONAL","Observational study:\n\nThe goal of this observational study is to learn about the association between slow wave activity before awakening and post-awakening psychomotor vigilance task in time-fixed, 2-hour, simulated night naps in healthy individuals.\n\nThe main question aims to answer is:\n\nIs the quantity of slow wave activity immediately before awakening associated with post-awakening psychomotor vigilance task metrics when awakened after 2-hour nap at night?",[63,64,27],"Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization","Sleep Inertia",[66,67],"sleep inertia","nap","2026-02-06",{"date":70,"type":40},"2026-02-13",{"date":72,"type":21},"2026-02-04",{"date":74,"type":21},"2026-08-30",{"name":76,"class":47},"Mahidol University",1,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":95,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":77},"100584592","optimization-of-chrononutrition-to-reduce-the-risk-of-disease-in-shift-workers-100584592","NCT06891352","Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers","Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers - The SHIFT Study","SHIFT","Inclusion Criteria:\n\n* Age: 18-70 years\n* BMI ≥ 25 kg\u002Fm2 (or ≥ 23 kg\u002Fm2 for Asian adults)\n* Own a smartphone (Apple iOS or Android OS)\n* Baseline eating window ≥ 14 h\u002Fday\n* Night shift nurses and nursing assistants who are working a 12-hour night shift at least 3 days\u002Fweek.\n* Have been doing night shift work for at least 3 months.\n* Patients on cardiovascular medications (HMG CoA reductase inhibitors (statins), metformin, lipid-modifying drugs (including over-the-counter drugs such as red yeast rice and fish oil), anti-hypertensive, drugs), are allowed\n* If patients have Type 2 Diabetes, they will be included in the study if A1c is less than 9 and they are not on insulin.\n\nExclusion Criteria:\n\n* Insufficient dietary logging on the mCC app is defined as less than 7 of 14 days of baseline of dietary logging with a minimum of 2 items a day, at least 5 hours apart.\n* Type 1 Diabetes or Insulin-dependent Type 2 Diabetes.\n* Use of sulfonylurea or insulin within the last 3 months (due to unknown safety with TRE)\n* Use of medications that are known to cause weight loss such as SGLT2 inhibitors and GLP1 receptor agonists)\n* BMI \\> 50 kg\u002Fm2\n* Change in medications that could impact study outcomes within the past 3 months\n* Change in weight of \\>4kg in the past 3 months\n* Women who are pregnant, breastfeeding, or are trying to become pregnant during the study period. If a participant becomes pregnant during the study, they will be excluded from continuing the study.\n* Systolic BP greater than 160 mmHg and\u002For diastolic BP greater than 110 mmHg at rest\n* Fasting LDL cholesterol greater than 250 mg\u002FdL\n* Fasting triglycerides greater than 500g\u002FdL\n* Active tobacco abuse or illicit drug use or history of treatment for alcohol abuse in the past 5 years.\n* Frequent (more than 4) travel involving a time zone change of more than 3 hours over the 1-year study period\n* Prolonged leave from work (a continuous month or longer) during the study\n* Active treatment for inflammatory and\u002For rheumatologic disease\n* History of a major adverse cardiovascular event within the past year (acute coronary syndrome, percutaneous coronary intervention, coronary artery bypass graft surgery, hospitalization for congestive heart failure, stroke\u002Ftransient ischemic attack)\n* Uncontrolled arrhythmia (i.e. rate-controlled atrial fibrillation\u002Fatrial flutter are acceptable)\n* History of thyroid disease requiring dose titration of thyroid replacement medication(s) within the past 3 months (hypothyroidism on a stable dose of thyroid replacement therapy is allowed).\n* History of adrenal disease in the past 5 years\n* History of malignancy undergoing active treatment, except non-melanoma skin cancer, in the past 5 years\n* History of an eating disorder in the past 5 years\n* History of cirrhosis in the past 5 years\n* History of stage 4 or 5 chronic kidney disease or dialysis in the past 5 years\n* History of HIV\u002FAIDs\n* Currently enrolled in weight-loss or weight-management program\n* History of surgical intervention for weight management within the past 2 years, or longer if deemed unsafe following review by medical investigators\n* Uncontrolled psychiatric disorder including prior hospitalization","70 Years",{"count":88,"type":21},180,[24],"In this randomized controlled trial, the investigators will assess the health impacts of optimizing the timing of dietary consumption in nurses and nursing assistants who work night shifts, have a habitual eating window of 14 hours or more, and elevated weight. Participants will be randomized to one of three groups: (1) dietary monitoring, (2) dietary monitoring plus 10-hour daytime time-restricted eating (TRE), or (3) TRE with a low-glycemic snack during night shifts. The study includes a 2-week screening\u002Fbaseline health assessment, with follow-up health assessments at 3-, 6- (primary outcome), and 12 months.",[27,92,93,94],"Time Restricted Eating","Overweight","Obesity",[96,97,98,99],"Time-Restricted Eating","Night Shift work","Nurses","Nursing Assistants","RECRUITING","2025-12-12",{"date":103,"type":40},"2025-12-17",{"date":105,"type":40},"2025-06-02",{"date":107,"type":21},"2029-03-03",{"name":109,"class":47},"Salk Institute for Biological Studies"]