[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"no-condition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:no-condition":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,69,95,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100616237","real-time-monitoring-of-the-injection-pressure-during-the-peripheral-nerve-block-100616237",false,"NCT07302997","Real-Time Monitoring of the Injection Pressure During the Peripheral Nerve Block","A Single-Center, First-in-Human, Randomized, Controlled, Feasibility Study of a New Device for the Real-Time Continuous Monitoring of the Injection Pressure of Local Anesthetic in Subjects Undergoing Ultrasound-guided Peripheral Nerve Block: the Smart Needle Monitoring System Investigation","Smart Needle","Inclusion Criteria:\n\n* Informed Consent signed by the subject\n* Age ≥ 18 years\n* Scheduled for elective surgery below the elbow (e.g., hand surgery, distal radius surgery, forearm surgery) requiring an axillary block\n* ASA physical status I-III\n* Ability to understand the investigation\n* Ability and willingness to follow and complete the procedures of the investigation\n\nExclusion Criteria:\n\n* Contraindications to the axillary block (e.g., local infection)\n* Refusal of locoregional anesthesia for the surgical procedure\n* Pre-existing neurologic deficits in the operative extremity\n* Body Mass Index ≥ 35 kg\u002Fm2\n* Known allergy to local anesthetic (mepicavaine hydrochloride)\n* Inability to comply with post-operative evaluations e.g. due to language problems, psychological disorders, dementia, etc. of the subject","ALL","18 Years",{"count":20,"type":21},34,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial with medical device is to learn if the Smart Needle Monitoring System works to maintain a safe low injection pressure during a type of regional anaesthetic (Peripheral Nerve Block (PNB)) in patients due to undergo surgery below the elbow . It will also learn about the safety of the device and patients' perception of the quality of anesthesia.\n\nParticipants will:\n\n* be operated locally according to standard clinical practice\n* undergo post-anesthesia recovery and any neurologic symptoms or signs assessment on postoperative days 1 and 7",[27,28],"No Condition","Real-time Monitoring of the Injection Pressure During Ultrasound-guided Axillary Block",[30,31,32],"axillary block","injection pressure","real-time monitoring","RECRUITING","2026-03-12",{"date":36,"type":37},"2026-03-13","ACTUAL",{"date":39,"type":37},"2025-12-19",{"date":41,"type":21},"2026-12",{"name":43,"class":44},"Ente Ospedaliero Cantonale, Bellinzona","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":45},"100609981","carotenoids-in-the-skin-and-immune-aging-100609981","NCT07221643","Carotenoids in the Skin and Immune Aging","Carotenoids in the Skin and Immune Aging: a Pilot Observational Study","Inclusion Criteria:\n\n* Willing and able to provide written informed consent\n* Age 18-30 years OR 65 years and older\n* Healthy individuals without uncontrolled medical conditions (over the counter inhaled and topical steroids allowed)\n* Fiitzpatrick I-VI (all skin types)\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding\n* uncontrolled medical conditions\n* Skin conditions on the upper extremity that would interfere with skin measurements of carotenoid levels such as active atopic dermatitis or psoriasis\n* Concurrent use of medications that affect the immune system, within 4 weeks of enrollment (eg. prednisone, biologics, methotrexate, rapamycin, prescription topical steroids, prescription inhaled steroids, others)\n* Unable to follow study protocol",true,{"count":55,"type":21},40,"OBSERVATIONAL","This study aims to examine the connection between the level of carotenoids in the skin and a number of immune related health parameters.",[27,59],"Skin Carotenoids and Immune-aging","2025-12-11",{"date":62,"type":37},"2025-12-15",{"date":64,"type":37},"2025-10-09",{"date":66,"type":21},"2026-04-01",{"name":68,"class":44},"Stanford University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":77,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":94},"100601453","novel-multimodal-neural-physiological-and-behavioral-sensing-and-machine-learning-for-mental-states-100601453","NCT07110688","Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States","For the healthy population, all subjects over the age of 18 who are able and willing to give informed consent will be eligible.\n\nFor the epilepsy population, inclusion criteria are:\n\n* Patients who suffer from drug-resistant epilepsy and already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for their standard seizure localization (unrelated to our study) will be eligible. Most patients are healthy adults outside of their epilepsy.\n* Subjects \\>= 18 are only included in this study.\n* All patients with the above conditions and with already-implanted electrodes who are willing to participate and able to cooperate and follow research instructions will be recruited.",{"count":76,"type":21},90,[24],"In this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor for physiological and biochemical sensing; a conversational virtual human platform to evoke naturalistic social processes; audiovisual affect recognition software; synchronization tools; and machine learning methods to model the multimodal data. The investigators will demonstrate the tools in healthy subjects without neural recordings and in patients with drug-resistant epilepsy who already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for standard monitoring to localize seizures, which is unrelated to our study.",[27,80],"Study Mental State in Healthy Populations and Drug-resistant Epilepsy Patients With Existing iEEG",[82,83,84],"neurotechnology","neuropsychiatric disorders","brain-machine interface","2025-09-26",{"date":87,"type":37},"2025-10-01",{"date":89,"type":37},"2024-08-01",{"date":91,"type":21},"2028-11-30",{"name":93,"class":44},"University of Southern California",2,{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":53,"sex":17,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":105,"conditions":106,"keywords":107,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":119,"locationsCount":45},"100578210","clair-pivotal-study-100578210","NCT06808334","CLAiR Pivotal Study","Inclusion Criteria:\n\n1. Male or female, aged 40-75 years\n2. Participants must be capable of providing informed consent, demonstrating understanding of the study details, and willingly sign a consent form or verbally confirm their consent in the presence of a witness.\n3. Stated willingness to comply with all study procedures and availability for the duration of the study\n\nExclusion Criteria:\n\nAn individual who meets any of the following criteria will be excluded from participation in this study:\n\n1. Known history of atherosclerotic cardiovascular disease, including stroke, heart attack, coronary artery surgery, or stenting\n2. Current use of cholesterol-lowering medication, such as a statin\n3. Pregnancy\n4. A person who has (in at least one eye):\n\n   * Persistent vision impairment: legally blind when wearing current driving glasses or known VA\\\u003C20\u002F400\n   * Known pathological myopia\n   * Previous treatment or currently under the care for a retinal disease by a specialist (e.g., ophthalmologist)","40 Years","75 Years",{"count":104,"type":21},942,"This is a multi-site, observational clinical study to validate the performance of the CLAiR AI software in identifying elevated atherosclerotic cardiovascular disease (ASCVD) risk from retinal (eye) images obtained from two different retinal image camera models.",[27],[108,109,110,111,112],"retinal image","ASCVD","AI","cardiovascular risk","adults","2025-03-20",{"date":115,"type":37},"2025-03-25",{"date":117,"type":37},"2025-02-27",{"date":87,"type":21},{"name":120,"class":121},"Toku Eyes Ltd","INDUSTRY",{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":128,"eligibilityCriteria":129,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":141,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":45},"100577568","nutfinforce-the-impact-of-digitally-delivered-lifestyle-performance-medicine-intervention-on-defense-performance-in-finland-100577568","NCT06799988","NutFinForce: The Impact of Digitally Delivered Lifestyle Performance Medicine Intervention on Defense Performance in Finland","NUTFINFORCE: THE IMPACT OF DIGITALLY DELIVERED LIFESTYLE PERFORMANCE MEDICINE INTERVENTION ON DEFENSE PERFORMANCE IN FINLAND","NutFinForce","Inclusion Criteria:\n\n* The participants for the intervention are recruited along with the invitation process of the Finnish Defense Forces in such a way that it does not interfere with the actual goal itself: attending the military service.\n\nAttendance for the intervention, suspension of the intervention or not attending is not known by the Defense Forces and does not influence terms of service\n\nExclusion Criteria:\n\n* Not attending the military service","30 Years",{"count":132,"type":21},5000,"Summaries are in Finnish for attendees are availabe and reviewed in ethical approcval process",[27],[136,137,138,139,140],"Nutrition","Eating habits","Digital","Behavior change","Performance medicine","NOT_YET_RECRUITING","2025-01-23",{"date":144,"type":37},"2025-01-29",{"date":146,"type":21},"2025-03-15",{"date":148,"type":21},"2029-12-31",{"name":150,"class":44},"University of Helsinki"]