[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"no-disease-or-condition-is-being-studied\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:no-disease-or-condition-is-being-studied":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,72,95,123],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100638223","hand-versus-foot-controls-for-robotic-surgery-simulation-100638223",false,"NCT07618429","Hand Versus Foot Controls for Robotic Surgery Simulation","Control Location Using Two Commands: Hand Versus Foot, Workload and Accuracy Response Trial: A Randomized Controlled Trial in Robotic Surgery Simulation","CLUTCH WAR","Inclusion Criteria:\n\n* Active surgical trainees (residents or fellows) currently enrolled in a recognized surgical specialty program, including general surgery, obstetrics and gynecology, urology, cardiothoracic surgery or pediatric surgery, at Prince of Songkla University\n* Complete absence of prior hands-on experience performing clinical robotic surgery or undergoing formalized robotic simulator training\n\nExclusion Criteria:\n\n* Pre-existing physical, orthopedic, or neurological conditions that impair standard motor function of the upper or lower limbs, including active movement disorders or motor control deficits capable of confounding objective simulation performance metrics.",true,"ALL","18 Years",{"count":21,"type":22},86,"ESTIMATED","INTERVENTIONAL",[25],"NA","Why is the study being done? Robotic-assisted surgery offers high precision and ergonomic benefits, but it requires specialized console skills that differ significantly from traditional open or laparoscopic surgery. A fundamental part of operating a robotic surgical system is clutch control, which allows surgeons to reposition their controllers without moving the actual surgical instruments. Inefficient clutching can disrupt workflow, increase mental workload, and lead to operator fatigue.\n\nModern platforms like the Da Vinci Xi offer two main options for clutching: hand-controlled clutching and foot-controlled clutching. Currently, there is limited research isolating how these different clutch options affect performance, especially for novice operators who have no prior robotic experience. This study aims to evaluate and compare hand clutch versus foot clutch methods to determine which approach better supports efficient skill acquisition, precision, and comfort for beginners.\n\nWhat happens during the study? Surgical trainees with no prior robotic surgery experience will be recruited for this study. After completing an initial baseline questionnaire and receiving a standardized orientation on the equipment, all participants will undergo a 20-minute practice session where they get to try both hand and foot clutching mechanisms.\n\nOne week after the practice session, participants will return for the formal evaluation and be randomly assigned to one of two groups:\n\n1. Hand Clutch Group: Participants will complete a standardized simulation task using only the hand clutch button.\n2. Foot Clutch Group: Participants will complete the exact same simulation task using only the foot clutch pedal.\n\nThe simulator automatically tracks performance metrics such as task completion time, movement efficiency, instrument collisions, and technical errors. Immediately following the test, participants will fill out a short survey rating their satisfaction, comfort, and the learning difficulty of their assigned clutch method.",[28,29],"No Disease or Condition is Being Studied","Surgical Procedures, Minimally Invasive",[31,32,33,34,35],"Robotic surgery","Surgical simulation","Psychomotor skill acquisition","Technical performance metrics","Randomized controlled trial","NOT_YET_RECRUITING","2026-05-29",{"date":39,"type":40},"2026-06-02","ACTUAL",{"date":42,"type":22},"2026-06-15",{"date":44,"type":22},"2026-10-31",{"name":46,"class":47},"Prince of Songkla University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":48},"100635237","caring-for-dementia-caregivers-in-ethnic-immigrant-communities-100635237","NCT07550075","Caring for Dementia Caregivers in Ethnic Immigrant Communities","Inclusion Criteria:\n\nSelf-identified Korean American adults aged 18 or older Provide care for a family member with dementia as a primary caregiver Primary caregiver defined as providing a minimum of 10 hours per week of in-home caregiving to a family member Speak English less than \"very well\" Able to attend virtual classes using an electronic device with Internet access\n\nExclusion Criteria:\n\nIndividuals with severe depression (Patient Health Questionnaire \\[PHQ-9\\] score ≥ 20), as K-Savvy is not a mental health treatment program",{"count":56,"type":22},120,[25],"Many caregivers of people with Alzheimer's disease or other dementias-especially those in immigrant communities who don't speak English well-don't get access to helpful, proven support programs. This is especially true for Korean American caregivers.\n\nTo address this, the investigative team adapted an existing caregiver support program (called the Savvy Caregiver Program) to better fit Korean culture and language. This new version, called K-Savvy, is a 6-week online program taught in Korean. In an earlier small study, K-Savvy worked well: caregivers found it helpful, were willing to use it, and showed fewer symptoms of depression.\n\nNow, the investigative team wants to study it more carefully to see how well it really works and why.\n\nThe study has two main goals:\n\nGoal 1:\n\nThe investigative team will measure whether K-Savvy improves caregivers' well-being-specifically whether it reduces stress and depression and helps them feel more positive about caregiving. The investigative team will also look at why it works, focusing on whether it changes how caregivers think about their situation (for example, feeling less overwhelmed and more confident).\n\nGoal 2:\n\nThe investigative team will talk directly with caregivers and program instructors to understand their experiences with K-Savvy. This will help the investigative team learn what worked well, what didn't, and why.",[28,60],"Stress (Psychology)",[62],"K-Savvy","2026-04-28",{"date":65,"type":40},"2026-04-30",{"date":67,"type":22},"2026-05-01",{"date":69,"type":22},"2030-12-30",{"name":71,"class":47},"University of Southern California",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":4},"100624348","optimizing-operational-parameters-for-diagnostic-vitrectomy-100624348","NCT07408466","Optimizing Operational Parameters for Diagnostic Vitrectomy","Optimizing Operational Parameters to Preserve Cellular Integrity During Diagnostic Vitrectomy: An Ex-Vivo Pilot Study With Blinded Outcome Assessment","CELLVIT","Inclusion Criteria:\n\n* Provision of written informed consent authorizing the anonymized research use of residual blood samples.\n* Age 18-65 years at the time of donation.\n* Eligibility for routine whole blood donation, according to the institutional and national standards of the Blood Transfusion Center.\n* Good general health, as per standard donor screening procedures.\n\nExclusion Criteria:\n\nNo additional exclusion criteria are defined beyond standard blood donation regulations. Exclusion from the study will therefore coincide with ineligibility for blood donation according to institutional protocols (e.g., due to infection, hematologic disease, recent surgery, or medication use that affects blood composition).","65 Years",{"count":82,"type":22},100,"OBSERVATIONAL","Single-center ex-vivo study using blood samples from healthy donors processed through a 25-gauge vitrectomy system. The study compares four combinations of operational parameters (vacuum pressure and cut rate) to evaluate their impact on cellular recovery and morphological preservation. Pre- and post-procedure complete blood counts and cytology smears will be analyzed to identify the settings that minimize cell loss and mechanical damage, with the ultimate goal of optimizing diagnostic yield in vitreoretinal lymphoma (VRL) vitrectomy.",[28],"2026-02-12",{"date":88,"type":40},"2026-02-17",{"date":90,"type":22},"2026-04",{"date":92,"type":22},"2026-12",{"name":94,"class":47},"IRCCS San Raffaele",{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":23,"phases":105,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":119,"leadSponsor":121,"locationsCount":48},"100611377","role-of-the-noradrenergic-system-in-the-regulation-of-learning-dynamics-evaluation-of-the-effect-of-a-low-dose-selective-noradrenaline-reuptake-inhibitor-noisyxetine-100611377","NCT07239791","Role of the Noradrenergic System in the Regulation of Learning Dynamics: Evaluation of the Effect of a Low-dose Selective Noradrenaline Reuptake Inhibitor (NOISYXETINE)","NOISYXETINE","Inclusion Criteria:\n\n* Right-handed, assessed by the Edinburgh scale;\n* Written signed informed consent;\n* Subject covered by a social security regimen.\n\nExclusion Criteria:\n\n* Pregnant, parturient or breastfeeding woman;\n* First-degree family history of axis I disorder (DSM-IV-TR), excepted unipolar mood and anxiety disorders with OCD;\n* Personal history of axis I disorder (DSM-IV-TR) in the 6 months preceding the study entry;\n* Dependence on a psychoactive substance in the 12 months preceding the study entry, excluding nicotine, any behavioural disorder incompatible with a 2-hour electroencephalographic recording;\n* Neuro\u002Fpsychotropic treatment ongoing or stopped less than 1 month ago;\n* Personal history of neurological pathology (e.g.: congenital malformation, benign or malignant tumour, degenerative disease of the central nervous system (CNS), epilepsy, inflammatory or infectious disease of the CNS, etc.);\n* Personal history of chronic disease of infectious, neoplastic, vascular, dysimmune or inflammatory, metabolic or endocrine, degenerative or genetic aetiology. In particular, angle-closure glaucoma, pheochromocytoma, known high blood pressure or measured blood pressure greater than 140\u002F90 mm Hg at baseline, congenital heart disease, known ischemic heart disease, known heart failure, supraventricular or ventricular heart rhythm disorder, nephropathy, known liver disease and any pathology likely to be aggravated by an increase in blood pressure;\n* Any medical treatment in the month preceding the study entry, apart from effective contraceptive treatment;\n* Subject deprived of liberty by a judicial or administrative decision;\n* Person subject to a legal protection measure or unable to express consent;\n* Known intolerance to atomoxetine;\n* Need to wear glasses and\u002For lenses to obtain normal vision;\n* Subject in an exclusion period or enrolled in an interventional study.","39 Years",{"count":104,"type":22},160,[25],"Administration of low-dose selective noradrenaline reuptake inhibitor (sNRI) (e.g. atomoxetine) to healthy subjects is a validated model of increasing cortical noradrenaline levels which, combined with computational modelling of behaviour, allows fine-grained analysis of the impact on learning processes of noradrenaline's fluctuations in the human cortex.\n\nThe study goal is to characterize the modifications of certain cognitive processes and associated brain circuits under low-dose sNRI using validated computational learning models. The study will be interested in how subjects will modify their learning under the effect of the drug across two separate investigations; one utilizing in a stable evidence accumulation task and one utilising a changing evidence accumulation task. This approach will help to better understand the link between noradrenaline and accumulation of evidence in healthy subjects, and indirectly in some neuropsychiatric pathologies.\n\nThe study is a single centre, double-blinded, randomized, placebo-controlled, cross-over study involving evaluable healthy adults separated in 2 cohorts: A for participants having the stable task and B for those having the changing one. Participants will then be randomized in a 1:1 ratio to one of the following treatment sequences:\n\n* Atomoxetine 40 mg - Placebo (Subgroups A1 or B1);\n* Placebo - Atomoxetine 40 mg (Subgroups A2 or B2).",[108,28],"Role of the Noradrenergic System in the Regulation of Learning Dynamics",[110,111,112,113],"noradrenaline","learning dynamics","atomoxetine","healthy subject","RECRUITING","2025-11-18",{"date":117,"type":40},"2025-11-20",{"date":115,"type":40},{"date":120,"type":22},"2027-12",{"name":122,"class":47},"Centre Hospitalier St Anne",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":23,"phases":132,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":48},"100576152","ergonomic-protocol-for-competitive-e-sport-athletes-100576152","NCT06781580","Ergonomic Protocol for Competitive E-Sport Athletes","The Effectiveness of an Ergonomic Protocol in Reducing Ergonomic Risk and Improving Performance for Competitive E-Sport Athletes","Inclusion Criteria:\n\n* 18+ years old\n* Primarily participates in PC games(s) using mouse and keyboard for at least a year\n* Plays at least 10 hours a week\n* Must be affiliated with an established Esports team or organization\n* Must have transportation\n\nExclusion Criteria:\n\n* Individuals currently receiving treatment for self-reported pain related to prolonged gaming\n* Those with a history of surgical procedures in the upper extremities\n* Individuals with cognitive impairments\n* Individuals with a history of a neck, shoulder, wrist, and\u002For back injury",{"count":131,"type":22},12,[25],"The goal of this clinical trial is to learn if this ergonomic protocol can improve performance and reduce ergonomic risk in esports athletes. It will also learn about the insight of esports athletes and their experience in implementing this new protocol. The main questions it aims to answer are:\n\nDoes this ergonomic protocol improve performance? Does this ergonomic protocol reduce ergonomic risk?\n\nResearchers will assign the protocol to esports athletes who meet inclusion criteria and express interest in participating in the study. A pre-post design will be conducted to note any differences.\n\nParticipants will:\n\n* Participate in a 6-week study with 4 in-person visits\n* Volunteers will be requested to participate in a focus group during Week 6.\n* Implement the strengthening protocol 3x a week and a warm up\u002Fcool down protocol before and after each gaming session.\n* Attend one educational session about gaming ergonomics during Week 1\n* Complete the Rapid Entire Body Assessment, Kovaaks Asessment, and a Questionnaire during Week Zero, Week 3, and Week 6.",[28],[136,137,138,139,140,141,142,143,144,145,146,147,148],"Ergonomics","Esports athletes","Gamers","Gaming","Ergonomic protocol","Musculoskeletal disorders","Ergonomic risk","Performance","Repetitive strain injuries","Accuracy","Aim","Postural rehabilitation","Esports","2025-02-26",{"date":151,"type":40},"2025-02-27",{"date":153,"type":40},"2025-02-01",{"date":155,"type":22},"2025-04",{"name":157,"class":47},"University of Nevada, Las Vegas"]