[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nociception-monitoring\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nociception-monitoring":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100626246","effect-of-rectus-block-timing-on-opioid-use-100626246",false,"NCT07433140","Effect of Rectus Block Timing on Opioid Use","The Effect of Timing of Rectus Sheath Blockade During Robotic Prostate Surgery on Opioid Consumption: A Randomized Double-Blind Study","PROSTIMERSBOP","Inclusion Criteria:\n\n-ASA (American Society of Anesthesiologists) I-III adult patients with prostate cancer and benign prostate diseases scheduled for robotic surgery at Koç University Hospital.\n\nExclusion Criteria:\n\n* \\\u003C18 years of age\n* ASA (American Society of Anesthesiologists) IV, V patients\n* Non-elective emergency cases\n* Previous major abdominal\u002Fpelvic surgery\n* History of significant psychiatric disorders\n* Patients who may have contraindications to nerve blocks (bleeding diathesis, infection, and local anesthetic allergy).","MALE","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this study is to observe the effect of administering local anesthetic to the abdominal wall at the beginning or end of surgery under general anesthesia on opioid consumption during surgery. The hypothesis of this study is to demonstrate that administering a rectus sheath block before the surgical procedure under general anesthesia is effective in reducing intraoperative opioid consumption and opioid-related side effects compared to administering it after the surgery is completed.",[27,28,29,30,31],"Prostate Cancer","Pain Management","Nociception Level Index(NoL)","Nociception Monitoring","Opioid Consumption",[33,34,35,36,37],"Robot Surgery","Rectus sheath block","Nociception","opioid","Cancer of Prostate","NOT_YET_RECRUITING","2026-02-19",{"date":41,"type":42},"2026-02-25","ACTUAL",{"date":44,"type":21},"2026-03-15",{"date":46,"type":21},"2026-07-01",{"name":48,"class":49},"Koc University Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":64,"studyType":65,"phases":4,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":50},"100599472","comparison-of-the-surgical-pleth-index-and-the-nociception-level-index-in-the-pediatric-population-100599472","NCT07084935","Comparison of the Surgical Pleth Index and the Nociception Level Index in the Pediatric Population","Comparison of the Surgical Pleth Index and the Nociception Level Index in the Pediatric Population: An Observational Study","NOLvsSPI","Inclusion Criteria:\n\n* Male or female\n* ASA I, ASA II and ASA III\n* Aged 1 to 12 years old\n* Scheduled to undergo elective surgery with general anaesthesia\n\nExclusion Criteria:\n\n* Patients with chronic pain\n* Patients with chronic analgesia usage.\n* Known allergy to the adhesives used in the sensors.\n* No free available limb to attach the probes to.","ALL","1 Year","12 Years",{"count":63,"type":21},40,"1 Day","OBSERVATIONAL","This observational study aims to compare two nociception monitoring methods. The Nociception Level (NOL) index and the Surgical Pleth Index (SPI) in the pediatric population during general anesthesia. While both monitors are designed to assess nociceptive responses through autonomic nervous system activity, they differ in methodology and parameters measured. The NOL index integrates multiple physiological signals using a self-learning algorithm, while SPI focuses on heart rate variability and plethysmographic amplitude. Although both have been studied individually in children, a direct comparison has not yet been conducted. This study will evaluate and compare each monitor's ability to detect and quantify nociceptive stimuli (surgical and tetanic) in children.\n\nThe investigators hypothesize that the NOL monitor and SPI monitor will both be able to quantify surgical stimuli and tetanic stimuli with monitors response to surgical stimuli \\> monitors response to tetanic stimuli. However, the investigators also hypothesize that the NOL index will do this superiorly, as it utilizes a self-learning algorithm and more parameters are incorporated in its algorithm",[68,69,70,30],"Nociceptive Pain","Anesthesia","Pediatric Anesthesia",[72,73,74,75],"Nociception monitoring","Pediatric population","NOL index","Surgical pleth index","RECRUITING","2025-07-24",{"date":79,"type":42},"2025-07-25",{"date":81,"type":42},"2025-07-04",{"date":83,"type":21},"2026-07-31",{"name":85,"class":49},"Radboud University Medical Center"]