[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-celiac-glutenwheat-sensitivity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-celiac-glutenwheat-sensitivity":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100379379","urinary-gluten-immunogenic-peptides-detection-in-non-celiac-glutenwheat-sensitivity-100379379",false,"NCT04219813","Urinary Gluten Immunogenic Peptides Detection in Non-celiac Gluten\u002FWheat Sensitivity","Urinary Gluten Detection in Patients With Non-celiac Gluten\u002FWheat Sensitivity","Inclusion Criteria:\n\n* patients suffering from NCGS\u002FNCWS on Gluten-Free Diet (GFD).\n\nExclusion Criteria:\n\n* celiac patients or those suffering from IgE-mediated gluten\u002Fwheat allergy.","ALL","18 Years","75 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Non-celiac gluten\u002Fwheat sensitivity (NCGS\u002FNCWS) is a syndrome characterized by both intestinal (irritable bowel syndrome \\[IBS\\]-like presentation) and extraintestinal symptoms (headache, migraine, \"foggy mind\", depression, anxiety, fibromyalgia, joint and muscle pain, leg or arm numbness, eczema or skin rash), which occur after the ingestion of gluten\u002Fwheat in subjects in which celiac disease (CD) and wheat allergy diagnosis has been previously excluded. NCGS\u002FNCWS symptoms generally occur after the ingestion of gluten\u002Fwheat, disappear within a few days of a gluten-free diet (GFD) and quickly reappear when gluten\u002Fwheat is reintroduced. A new assay, recently available on the Italian market, allows to ascertain the presence of immunogenic peptides of gluten (Gluten Immunogenic Peptides, GIP) in the urine and stool. The test might allow to ascertain if the NCGS\u002FNCWS patients, on GFD, eat, even accidentally, gluten. Of the 2 available assays, the urinary one allows the patient himself to test the presence of GIP in relation to symptoms\u002Fsigns appearing and\u002For social activities (e.g. meal in a restaurant). The aims of the present study are: 1) to test, in patients with NCGS\u002FNCWS on GFD, the adherence to the elimination diet; 2) to evaluate the correlation between the symptoms' reappearance and the presence of GIP in the urine.",[27],"Non-celiac Gluten\u002FWheat Sensitivity",[27,29,30],"Gluten Immunogenic Peptides","Celiac Disease","RECRUITING","2026-04-28",{"date":34,"type":35},"2026-04-29","ACTUAL",{"date":37,"type":35},"2021-01-01",{"date":39,"type":21},"2026-12-31",{"name":41,"class":42},"University of Palermo","OTHER",2]