[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-communicable-diseases-ncd\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-communicable-diseases-ncd":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100626952","enabling-environments-for-non-communicable-disease-risk-reduction-in-ethiopia-100626952",false,"NCT07442318","Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia","Enhancing Non-Communicable Disease Prevention Among Pregnant Women Through Healthy Lifestyle Promotion in Four Urban Sites in Ethiopia: A Cluster Randomized Controlled Trial in Primary Health Care Facilities","ENABLE","Inclusion Criteria:\n\n* Pregnant women aged 18 years or older\n* Gestational age ≤20 weeks at the time of enrollment\n* Residing in one of the four study cities (Addis Ababa, Adama, Harar, or Jimma)\n* Attending their first antenatal care visit at one of the participating public health facilities\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Pregnant women identified as high risk at enrollment, including those with pre-existing medical conditions, or other conditions requiring specialized care and who cannot continue receiving standard routine ANC.",true,"FEMALE","18 Years",{"count":21,"type":22},1268,"ESTIMATED","INTERVENTIONAL",[25],"NA","The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities. Many women in this setting face increased health risks due to unhealthy diets, low physical activity, and exposure to air pollution which can affect both maternal and newborn health and increase the risk of non-communicable diseases (NCDs) later in life.\n\nIn this study, pregnant women in intervention health centers receive structured, tailored counseling as part of their regular ANC visits. This counseling supports healthier eating, physical activity and reduced exposure to air pollution. Health care providers, including health workers in health centers and Urban Health Extension Professionals (UHEPs), are trained to deliver this counseling supported by a digital ANC eRegistry for clinical decision-making, which enhances adherence to national guidelines, and strengthens the quality of care. Facilitators further strengthen the intervention's implementation by ensuring fidelity to counseling protocols and by adapting content to the Ethiopian urban health system context.\n\nThe study hypothesis is that integrating lifestyle counseling into routine ANC will improve maternal health behaviors and pregnancy outcomes, and reduce NCD risk among pregnant women, compared with standard routine ANC alone.\n\nBy embedding NCD prevention within routine maternal health services, the ENABLE study aims to strengthen the role of ANC as a platform for early prevention and long-term health benefits for women and their children.",[28],"Non-communicable Diseases (NCD)",[30,31,32,33,34,35,36,37,38,39,40,41],"Antenatal care","Pregnancy","Primary Health Care","Behavioral Counseling","Digital Health","Chronic Disease Risk Factors","Health Promotion","Dietary Behavior","Physical Activity","Air Pollution","Health Services Research","Clinical Decision Support Systems","RECRUITING","2026-05-27",{"date":45,"type":46},"2026-05-28","ACTUAL",{"date":48,"type":46},"2026-05-11",{"date":50,"type":22},"2027-05",{"name":52,"class":53},"Norwegian Institute of Public Health","OTHER_GOV",4,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":17,"sex":63,"minAge":19,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":66,"phases":4,"briefSummary":67,"conditions":68,"keywords":72,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":97},"100635861","systematic-examination-of-health-inequalities-documentation-patterns-and-determinants-100635861","NCT07558187","Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants","Assessment of Lifestyle Parameters and Biomarkers of Biochemistry and Physiology to Address Health Inequalities: An Exploratory Cohort Study","CHANCE","Inclusion Criteria:\n\n* Adults (\\>18 years of age)\n* All healthy individuals who reside in rural and urban areas\n* All patients with non-communicable diseases who reside in rural and urban areas\n* Patients with opioid use disorders under medication for addiction treatment with methadone and buprenorphine\n* Individuals incarcerated in correctional facilities\n\nExclusion Criteria:\n\n* Minors (\\\u003C18 years of age)\n* Individuals with communicable diseases","ALL",{"count":65,"type":22},2000,"OBSERVATIONAL","The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident. Indeed, the low-income residents in several European countries, including Greece, had limited access to the healthcare system for several reasons. In addition, vulnerable populations, with patients suffering from opioid use disorders and incarcerated individuals being among them, do not have the same chances regarding health services, compared to the general population. According to the World Health Organization, physical activity is a key non-pharmaceutical intervention for both prevention of chronic non-communicable diseases and address of social health inequalities. Thus, this study will focus on specific population groups of the Region of Thessaly, Greece, who have limited access to healthcare services. It aims, primarily, to the assessment of demographic characteristics (i.e., body mass index, alcohol consumption, smoking, educational level etc), which are fundamental parameters for the assessment of health inequalities. Secondly, quality of life, physical activity levels and biomarkers in the level of Biochemistry (i.e., blood oxidative stress and inflammation) and Physiology (i.e., cardiorespiratory fitness, body composition) will be collected a well. All data will be integrated into an interactive digital platform that will be accessible by any putative stakeholder in the area of health system or administration. Based on scientifically robust data and evidence-based findings, the research team of the project will draft recommendations and guidelines that will be communicated to all stakeholders. To that end, the problem of limited access to health system that the examined populations face, will be highlighted and targeted actions and policies are expected to be adopted by local (i.e., in the province of Thessaly) and national (i.e., Greek) authorities. In this respect, non-pharmaceutical interventions and guidelines will be proposed towards the trajectory of holistically approaching the issue of health inequalities.",[28,69,70,71],"Addiction to Opioids","Incarceration","Opioid-use Disorders",[73,74,75,76,77,78,79,80,81,82,83,84,85,86],"Health inequalities","Physical activity\u002Fexercise","Demographics","Quality of life","Heroin craving","Oxidative stress","Antioxidants","Resting energy expenditure","Body composition","Alcohol","Body mass index","Smoking","Cardiorespiratory fitness","Opioid use disorders","2026-04-22",{"date":89,"type":46},"2026-04-30",{"date":91,"type":46},"2026-03-10",{"date":93,"type":22},"2028-12",{"name":95,"class":96},"University of Thessaly","OTHER",5]