[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-convulsive-status-epilepticus\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-convulsive-status-epilepticus":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100459519","phase-3-fast-acute-sedation-at-intensive-care-vs-high-dose-iv-anti-seizure-medication-for-treatment-of-non-convulsive-status-epilepticus-fast-trial-100459519",false,"NCT05263674","Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial)","FAST","Inclusion Criteria:\n\n* Adult patients (older than 18 years) with EEG-verified NCSE, according to the Salzburg criteria, who have not responded to appropriate treatment with benzodiazepines and at least one 2nd line i.v. anti-seizure medication according to the current Danish national neurological treatment guidelines (Levetiracetam, Fosfenytoin or Valproate).\n\nExclusion Criteria:\n\n* patients with epilepticus status due to acute neuroinfection (e.g. bacterial meningitis or viral encephalitis)\n* acute traumatic or spontaneous intracranial hemorrhage\n* suspicion of cerebral anoxia \u002F hypoxia \u002F hypoglycemia \u002F epileptic encephalopathy\n* contraindications to anti-seizure medication defined in the protocol\n* contraindications to anesthesia treatment in intensive care\n* focal motor status epilepticus without relevant conscious influence (Glasgow Coma Scale\\> 13)\n* known epileptic encephalopathy\n* Clinical need for acute intubation","ALL","18 Years","120 Years",{"count":20,"type":21},140,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","This open-label, randomized multicenter trial aims at clarifying the standard of care of patients with non-convulsive status epilepticus not responding to treatment with benzodiazepines and at least one high-dose intra venous anti-seizure medication.",[27],"Non-Convulsive Status Epilepticus","RECRUITING","2026-05-01",{"date":31,"type":32},"2026-05-04","ACTUAL",{"date":34,"type":32},"2022-02-07",{"date":36,"type":21},"2028-12-31",{"name":38,"class":39},"University of Southern Denmark","OTHER",5,"Non-convulsive Status Epilepticus"]