[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-invasive\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-invasive":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100622612","ultrasound-guided-non-invasive-simulation-in-anesthesia-residency-training-100622612",false,"NCT07385885","Ultrasound-guided Non-invasive Simulation in Anesthesia Residency Training","Application of Ultrasound-guided Non-invasive Simulated Puncture Technique in Standardized Residency Training in Anesthesiology","non-invasive","Inclusion Criteria:\n\n\\~Anesthesiology residents participating in the standardized residency training program in the Department of Anesthesiology at Nanjing First Hospital between October 2024 and October 2026.\n\nExclusion Criteria:\n\n* Residents with prior experience in performing nerve block procedures.\n* Residents currently participating in other teaching or research studies related to nerve blocks.",true,"ALL",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Study Aim: This trial evaluates if a novel non-invasive, AI-assisted simulation training improves ultrasound-guided needle visualization skills in anesthesia residents.\n\nDesign: Trainees were randomized into two groups:\n\nIntervention: AI-based, non-invasive simulated needle puncture training. Control: Conventional ultrasound teaching. Key Outcomes: The primary outcome is objective needle tip visibility. Secondary outcomes include anatomical identification, correct view acquisition, operator confidence, and overall scanning performance.\n\nAssessment: Outcomes are measured via blinded expert evaluation and theoretical tests.\n\nThe goal of this randomized controlled clinical trial is to determine whether an ultrasound-guided non-invasive simulated needle puncture training technique can improve ultrasound-guided needle visualization skills in anesthesiology residents undergoing standardized residency training. The study is conducted in anesthesiology residents enrolled in a standardized residency training program.\n\nThe main questions it aims to answer are:\n\n1. Does non-invasive simulated needle puncture training improve objective needle tip visibility during ultrasound-guided peripheral nerve block procedures?\n2. Does this training method improve anatomical structure identification, acquisition of correct block views, operator confidence, and overall scanning performance compared with conventional ultrasound teaching? Researchers will compare a non-invasive simulated needle puncture training group with a conventional ultrasound teaching group to see if the simulated training technique leads to superior needle visualization and procedural performance.\n\nParticipants will:\n\nReceive standardized theoretical instruction on ultrasound- guided peripheral nerve blocks; Be randomly assigned to either non-invasive simulated needle puncture training using an artificial intelligence-assisted system or conventional ultrasound scanning training; Perform ultrasound scanning and simulated or conventional practice on healthy volunteers; Undergo theoretical examinations and blinded expert assessments of ultrasound scanning performance and needle visualization outcomes.",[27,28,29,30,31,32],"Ultrasound","Needle","Residency","Anesthesiology","Training","Non-invasive","NOT_YET_RECRUITING","2026-02-03",{"date":36,"type":37},"2026-02-04","ACTUAL",{"date":39,"type":21},"2026-02-01",{"date":41,"type":21},"2028-12-30",{"name":43,"class":44},"Nanjing First Hospital, Nanjing Medical University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":4,"maxAge":4,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":66,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":79,"locationsCount":4},"100567757","clinical-studies-of-endometrial-cytology-and-cervical-methylation-assays-in-endometrial-cancer-screening-and-fertility-preservation-evaluation-100567757","NCT06672341","Clinical Studies of Endometrial Cytology and Cervical Methylation Assays in Endometrial Cancer Screening and Fertility-Preservation Evaluation","A Prospective, Open, Observational Clinical Study on Endometrial Cytology and Cervical Methylation Testing for Screening and Evaluating Fertility-Sparing Treatment in Endometrial Cancer","Inclusion Criteria:\n\n* Participants must meet all of the following criteria to be eligible for the study:\n\n  1. Color Doppler ultrasound indicating intrauterine masses or abnormal endometrial thickening (for postmenopausal women not receiving hormone replacement therapy, endometrial thickness \\>5mm).\n  2. Patients undergoing follow-up and efficacy evaluation for fertility-sparing treatment of endometrial cancer or atypical endometrial hyperplasia.\n  3. Patients with endometrial thickening following endocrine therapy for breast cancer.\n  4. Signed informed consent form.\n  5. Good compliance.\n\nExclusion Criteria:\n\n* Participants meeting any of the following criteria will be excluded:\n\n  1. Diagnosed with cervical cancer.\n  2. Severe systemic complications preventing hysteroscopy.\n  3. Pregnant or recent history of miscarriage.\n  4. Acute genital tract infection or pelvic inflammatory disease.\n  5. Insertion of an intrauterine device.\n  6. Sexual activity, vaginal douching, or medication use within 24 hours.","FEMALE",{"count":55,"type":21},200,"1 Year","OBSERVATIONAL","The current study aims to assess high-risk patients using both liquid-based cytology and cervical methylation testing. The results will be compared with the traditional hysteroscopic pathological findings to determine the sensitivity and specificity of these methods for early detection of endometrial cancer, thereby evaluating their potential application in early screening.\n\nPrimary Objectives：\n\n1. To evaluate the sensitivity, specificity, and accuracy of endometrial cytology for screening endometrial cancer.\n2. To assess the sensitivity, specificity, and accuracy of methylation testing for screening endometrial cancer.\n3. To perform further molecular testing on tissue samples obtained from endometrial cytology and cervical methylation tests, aiming to explore early screening-sensitive indicators.\n\nSecondary Objectives：\n\n1. To determine the value of endometrial cytology in evaluating the efficacy of fertility-sparing treatments for endometrial cancer.\n2. To assess the value of methylation testing in evaluating the efficacy of fertility-sparing treatments for endometrial cancer.",[60,61,62,63,64,65,32],"Endometrial Cancer","Methylation","Cytology","Fertility Preservation","Screening Tool","Liquid Biopsy",[60,67,68,62,69,70,71,72,15],"screening","methylation","Liquid-Based Cytology Test","Early diagnosis","fertility-sparing","liquid biopsy","2024-11-03",{"date":75,"type":37},"2024-11-05",{"date":77,"type":21},"2024-11-04",{"date":39,"type":21},{"name":80,"class":44},"Yulan Ren"]