[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-pharmacological-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-pharmacological-intervention":60},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100644606","pbm-patch-for-postoperative-pain-relief-after-urological-surgery-100644606",false,"NCT07671612","PBM Patch for Postoperative Pain Relief After Urological Surgery","A Double-blind Randomized Controlled Clinical Study of the PBM Patch for Postoperative Pain Relief After Urological Surgery","Inclusion Criteria:\n\n1. Patients aged 18 years or older undergoing unilateral nephroureterectomy with bladder cuff excision, or adrenalectomy (tumor size \\\u003C 3.5 cm).\n2. Patients who are capable of clear verbal communication.\n3. Patients who are able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Individuals with photosensitive constitution or those currently using photosensitizing medications.\n2. Individuals with a known history of severe allergy or contact dermatitis to medical adhesive patches or tapes.\n3. Patients with severe psychiatric illness or cognitive impairment.\n4. Long-term or high-dose opioid users.\n5. Patients utilizing a Patient-Controlled Analgesia (PCA) pump.\n6. Individuals with severe hepatic insufficiency or active liver disease.\n7. Vulnerable populations, individuals with restricted legal capacity, or those who are unable or unwilling to undergo clinical evaluations.","ALL","18 Years",{"count":19,"type":20},300,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is a prospective, randomized, double-blind, placebo-controlled clinical study designed to evaluate the efficacy and safety of a photobiomodulation (PBM) patch (Super Vi PBM Patch - Soothing) and an enhanced PBM patch (Super Vi PBM Patch - Soothing EX), compared with a placebo patch, for postoperative pain relief following urological surgery, including nephroureterectomy with bladder cuff resection (NU+BCR) and adrenalectomy (ADRX).",[26,27,28,29,30],"Urological Surgery","Photobiomodulation (PBM)","Non-pharmacological Intervention","Double-blind Randomized Controlled Study","Postoperative Pain Relief",[30,27,26,29,28],"NOT_YET_RECRUITING","2026-06-25",{"date":35,"type":36},"2026-06-26","ACTUAL",{"date":38,"type":20},"2026-07-01",{"date":40,"type":20},"2028-03-31",{"name":42,"class":43},"National Taiwan University Hospital","OTHER",2,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100618718","effects-of-swaddling-and-nesting-on-pain-and-stress-in-newborns-100618718","NCT07335263","Effects of Swaddling and Nesting on Pain and Stress in Newborns","The Effect of Swaddling and Nesting Methods on Pain and Stress Levels in Newborns Undergoing Noninvasive Mechanical Ventilation","Inclusion Criteria:\n\n* Birth week greater than 35 weeks and birth weight greater than 2000 grams\n* Requirement for nasal CPAP\u002Fnoninvasive mechanical ventilation\n* Legal guardians' consent to participate in the study\n* Postnatal diagnosis of transient tachypnea of the newborn\n\nExclusion Criteria:\n\nMother:\n\n* Taking cortisol-containing medication during the antenatal period\n* Taking narcotics during the antenatal period\n* Having chorioamnionitis\n* Having a metabolic disorder (adrenal insufficiency, etc.)\n\nNewborn:\n\n* Amniotic fluid stained with meconium\n* Being intubated\n* Having an Apgar score below 6\n* Receiving analgesic or narcotic drugs for sedation\n* The newborn receiving cortisol-containing medication\n* Being unable to obtain a saliva sample or the sample being contaminated with blood\n* Signs of nasal injury during noninvasive mechanical ventilation\n* Congenital defects (spina bifida, gastroschisis, etc.) that prevent positioning using the swaddling or cradling methods\n* Resuscitation\n* Cerebral hypoxia-ischemia\n* Non-respiratory causes (congenital pneumonia, respiratory distress syndrome, congenital heart disease, hypocalcemia, persistent hypoglycemia, development of sepsis)\n* Hypocalcemia (low calcium level detected in blood gas sample taken while establishing an intravenous line prior to nCPAP)","0 Days","28 Days",{"count":55,"type":20},100,[23],"This study aims to investigate the effects of swaddling and cradling methods on pain and stress levels in newborn infants receiving respiratory support.\n\nInfants receiving respiratory support in the neonatal intensive care unit may experience stress and discomfort during treatment. In this study, two different care methods that help infants feel more comfortable and secure will be scientifically compared. Only one of the Swaddling or Nesting methods will be applied to the newborns participating in the study. These methods are comfort-enhancing care practices routinely used in neonatal intensive care that do not harm the baby. The newborn's heart rate, respiratory rate, oxygen level, pain and stress symptoms will be closely and safely monitored by the healthcare team. A pain-free saliva sample will be collected to assess the newborn's stress level. It does not involve needles, does not hurt, and takes approximately 2 minutes. Pain and stress levels will be assessed in a multifaceted manner using clinical observation, physiological parameters, and saliva cortisol levels. The study aims to contribute to the strengthening of evidence-based non-pharmacological care practices in neonatal intensive care.",[59,60,61],"Stress","Non Pharmacological Intervention","Newborn Diseases","RECRUITING","2026-01-23",{"date":65,"type":36},"2026-01-26",{"date":67,"type":36},"2025-02-17",{"date":69,"type":20},"2026-03-13",{"name":71,"class":43},"Kutahya Health Sciences University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":5},"100569032","neuropsychological-profiles-and-musical-engagement-in-parkinsons-and-alzheimers-disease-100569032","NCT06688968","Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease","Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment","MUSENGAGE","Inclusion Criteria:\n\nGeneral inclusion criteria:\n\n* 60 years and older\n* French-speaking and volunteering for the study\n* Living at home with a relative\n\nAlzheimer's disease inclusion criteria:\n\n* Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)\n* MMSE greater than or equal to 20\n\nInclusion criteria Parkinson's disease :\n\n* Diagnosis of Idiopathic Parkinson's disease\n* MMSE greater than or equal to 20\n\nExclusion Criteria:\n\n* No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)\n* Autistic disorders\n* History of stroke or head trauma\n* Unstable medical condition (cancer)\n* Subject unable to read and\u002For write\n* Hearing impairment without hearing aids\n* Refusal of consent after information\n* Persons unable to give consent, research carried out in emergency situations, etc.)\n* Non-affiliation with a social security scheme\n* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)\n* Person under legal protection (guardianship, curatorship, legal protection)\n* Person participating in another research project with an exclusion period still in progress",true,"60 Years",{"count":84,"type":20},120,[23],"The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects.\n\nThe main questions it aims to answer are:\n\n1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects.\n2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up.\n\nParticipants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including :\n\n* A semi-structured interview to check the participants eligibility and gather demographic data.\n* Neuropsychological tests and questionnaires will then be administered.\n* A relative of the study participant will help complete questionnaires.",[88,89,60],"Alzheimer Disease, Early Onset","Parkinsons Disease with Dementia",[91,88,89,92],"Non Pharmacological intervention","Music Therapy","2025-03-14",{"date":95,"type":36},"2025-03-19",{"date":97,"type":36},"2025-02-04",{"date":99,"type":20},"2025-12-01",{"name":101,"class":43},"University Hospital, Montpellier"]