[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-pharmacological-interventions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-pharmacological-interventions":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100638704","applied-research-on-a-non-pharmacological-intervention-program-for-older-adults-with-subjective-cognitive-decline-100638704",false,"NCT07629531","Applied Research on a Non-pharmacological Intervention Program for Older Adults With Subjective Cognitive Decline","Applied Research on a Group-based Non-pharmacological Intervention Program for Community-dwelling Older Adults With Subjective Cognitive Decline","Inclusion Criteria Aged ≥60 Community dwelling Subjective memory decline, confirmed by Subjective Cognitive Decline Questionnaire(SCD-Q9)≥5 Montreal Cognitive Assessment (MoCA) scores ≥19, 22, or 24 for participants who had primary school, middle school, or higher education, respectively Overall intact activities of daily living No planned exercise or cognitive intervention activities within the past six months Voluntary participants who will be informed of the study objectives by the researcher and will sign the informed consent form.\n\nExclusion Criteria Any other neurodegenerative diseases (such as mild cognitive impairment, dementia, Parkinson's disease, stroke, etc.) Any severe or unstable internal medical conditions (i.e., unstable or severe asthma or heart disease, liver and kidney diseases, uncontrolled hypertension, severe metabolic diseases, etc.) Severe depressive, anxiety or other psychiatric disorders Movement contraindications Those currently participating in other research trials.","ALL","60 Years","85 Years",{"count":20,"type":21},218,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to verify the short-term and long-term effects of a group-based non-pharmacological intervention program for community-dwelling older adults with subjective cognitive decline, and to evaluate its implementation outcomes, through a rigorously designed cluster randomized controlled trial.",[27],"Non-Pharmacological Interventions","NOT_YET_RECRUITING","2026-06-01",{"date":31,"type":32},"2026-06-05","ACTUAL",{"date":34,"type":21},"2026-06-30",{"date":36,"type":21},"2029-12-01",{"name":38,"class":39},"China Medical University, China","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100635236","effect-of-game-based-breathing-exercise-on-pain-fear-and-anxiety-in-children-during-venipuncture-100635236","NCT07550062","Effect Of Game-Based Breathing Exercise On Pain, Fear, And Anxiety In Children During Venipuncture","The Effect Of Video Game-Based Breathing Exercise Intervention On Pain, Fear, And Anxiety During Routine Venipuncture In Pediatric Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • Being between 7-12 years of age\n\n  * Undergoing a venipuncture procedure\n  * Able to understand and speak Turkish\n  * Having written informed consent from the parent\u002Flegal guardian and age-appropriate verbal assent from the child\n\nExclusion Criteria:\n\n* • History of epilepsy or recurrent seizures\n\n  * Presence of severe congenital chronic disease, congenital anomaly, or behavioral disorder\n  * Presence of visual or hearing impairment, or cognitive\u002Fdevelopmental delay\n  * Use of psychoactive medications\n  * Presence of oral, lip, or orofacial anomalies that may interfere with breathing exercises",true,"7 Years","12 Years",{"count":51,"type":21},60,[24],"Venipuncture is one of the most common invasive procedures in children and is often associated with significant pain, fear, and anxiety.This randomized controlled study will aim to evaluate the effects of a video game-based breathing exercise intervention on pain, fear, and anxiety levels in children aged 7-12 years undergoing routine venipuncture. While the intervention group will receive a video game-based breathing exercise using the BREATHING+ system in addition to standard care, the control group will receive routine venipuncture procedures only. The study population will consist of children aged 7-12 years who meet the inclusion criteria and whose parents\u002Flegal guardians provide informed consent. Participants will be randomly assigned to intervention and control groups. Pain, fear, and anxiety levels will be assessed at three time points: before the procedure, during the procedure, and immediately after the procedure. Data will be collected using the Visual Analog Scale (VAS), Children's Anxiety Scale-State (CAS-S), and Children's Fear Scale (CFS), along with a structured questionnaire form. All assessments will be conducted at the predefined time points.",[27,55,56,57],"Breathing Exercise","Venipuncture Pain","Pain Management",[59,60,61,62],"Pediatric venipuncture","Pain management","Breathing exercise","Non-pharmacological intervention","2026-04-17",{"date":65,"type":32},"2026-04-24",{"date":67,"type":21},"2026-05",{"date":69,"type":21},"2027-05",{"name":71,"class":39},"Uludag University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":96,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":114},"100617334","vr-pmr-for-post-burn-symptoms-100617334","NCT07317271","VR-PMR for Post-Burn Symptoms","Virtual Reality-Enhanced Progressive Muscle Relaxation for Symptom Management in Burn Survivors","VIBE","Inclusion criteria are:\n\n* ≥18 years old;\n* sustained a burn injury in the last 6 months or longer;\n* Score high on at least one of the following: Insomnia severity index (ISI) score of ≥8, Brief Pain Inventory Short Form (BPI-SF) Pain severity score of ≥3, or PROMIS Itch Severity of ≥55;\n* own a smartphone or computer with reliable internet connection for online visits and survey completion;\n* able to comfortably wear goggles or headsets on face as determined by self-report.\n\nExclusion criteria:\n\n* Cognitive impairment (Mini Mental Status Exam (MMSE) \\\u003C 25);\n* history of motion sickness, photosensitivity, photoinduced seizures, and claustrophobia as determined by self-report;\n* uncorrected visual or hearing impairments as determined by self-report;\n* non-English speaker.","18 Years",{"count":82,"type":21},34,[24],"The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors.\n\nThe main questions it aims to answer are:\n\n* Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR?\n* Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors?\n\nResearchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors.\n\nParticipants will:\n\n* Complete home-based sessions of VR-enhanced PMR\n* Complete home-based sessions of standard PMR\n* Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study\n* Use VR equipment provided for the intervention period (during the VR-PMR arm)",[86,87,27,88,89,90,91,92,93,94,95],"Burn","Chronic Pain Following Thermal Burn Injury","Virtual Reality","Sleep Disturbance","Anxiety","Depressive Symptoms","Fatigue Symptom","Pruritus","Burn Injury","Progressive Muscle Relaxation",[88,97,95,98,99,100,101,102,103,94],"Burn Survivors","Chronic Symptom Management","Pain","Itch","Sleep","Fatigue","Burns","RECRUITING","2026-03-03",{"date":107,"type":32},"2026-03-05",{"date":109,"type":32},"2026-02-27",{"date":111,"type":21},"2026-12",{"name":113,"class":39},"Johns Hopkins University",1]