[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-specific-chronic-low-back-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-specific-chronic-low-back-pain":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,47,77,103,133,157,180,216,243],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100639733","evaluating-the-efficacy-and-safety-of-octane-aether-for-treating-chronic-low-back-pain-100639733",false,"NCT07614568","Evaluating the Efficacy and Safety of Octane Aether for Treating Chronic Low Back Pain","A Randomized, Double-blind, Sham-controlled Study to Evaluate the Efficacy and Safety of the Octane [Aether] Bioelectricity Device for the Management of Chronic Low Back Pain","Inclusion Criteria:\n\n* Able to provide informed consent;\n* Aged 18-65;\n* Pain intensity of at least 5 on a numerical rating scale (0-10);\n* Experiencing chronic low back pain that has persisted for ≥3 months;\n* Pain localized primarily to the lumbar spine region;\n* Conservative treatments, such as physical therapy, NSAIDs and lifestyle changes, have failed over the past 6 months. Participants are allowed to continue conservative treatments, but changes to use\u002Ffrequency will be tracked; and\n* Must be able to attend 5 in-person clinic appointments over the 13-week study period.\n\nExclusion Criteria:\n\n* Began using new prescription medication for pain within the past 3 months;\n* Lumbar spine surgery (within the past 12 months);\n* Body Mass Index (BMI)\\> 35. The device may have diminished effectiveness and\u002For may not fit individuals with high BMI;\n* Presence of a cardiac pacemaker;\n* Pregnancy or breastfeeding;\n* Presence of ferromagnetic implants or body piercings (e.g., navel piercings) in the lumbar region, including hip implants\u002Freplacements or similar in the pelvic region, that could interfere with device function;\n* Inability to put on, adjust, and\u002For operate the wearable device without assistance;\n* Prior use of PEMF, or other electromagnetic field-emitting device, for the treatment of pain symptoms;\n* No, or inconsistent, access to internet (emailed surveys are used for daily data collection); and\n* Any condition or diagnosis that could in the opinion of the Principal Investigator or delegate interfere with the participant's ability to comply with study instructions, might confound the interpretation of the study results, or put the participant at risk.","ALL","18 Years","65 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate the safety of the Octane Aether device and to determine whether the device is effective in treating symptoms of non-specific chronic low back pain in adults. The Octane Aether is a wearable device that produces specific magnetic field outputs and is designed for daily use in a home setting. The main objectives of the trial are:\n\n* To measure the change in patient-reported pain scores during active treatment with the device compared to a sham treatment, and\n* To define and describe the adverse effects, if any, of the Octane Aether device when administered according to the protocol.\n\nEvery participant will evaluate three active output modes and a sham output using the same device. Patient-reported outcomes will inform the effectiveness of each output mode and help identify the need for personalization in magnetic field therapy.\n\nParticipants will:\n\n* Use the device at home for 60 minutes every day for 10 weeks,\n* Report daily pain scores using an electronic visual analog scale for pain intensity,\n* Visit the clinic 5 times over the course of the 13 week trial for checkups and device changes,\n* Respond to 3 phone calls for checkups, and\n* Fill various questionnaires related to disability, quality of life, and their back pain.",[27],"Non-specific Chronic Low Back Pain",[29,30,31,32,33],"low back pain","Electromagnetic field stimulation","Octane Aether","Pain management","EMF therapy","NOT_YET_RECRUITING","2026-05-27",{"date":37,"type":38},"2026-05-29","ACTUAL",{"date":40,"type":21},"2026-06",{"date":42,"type":21},"2027-07",{"name":44,"class":45},"Octane Innovation Inc.","INDUSTRY",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":46},"100619054","phase-1-sodium-aescinate-for-the-treatment-of-low-back-pain-lbp-in-adults-100619054","NCT07339631","Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults","The Safety and Clinical Efficacy of Sodium Aescinate: A Double-Blind, Randomized Controlled Trial for the Treatment of Low Back Pain (LBP) in Adults","Inclusion Criteria:\n\n1. Meets the diagnostic criteria for chronic low back pain (cLBP) recommended by the Clinical Practice Guidelines for Chronic Low Back Pain in China (2024 Edition): the course of disease lasts at least 12 weeks, with pain occurring in the region below the lower costal margin, above the gluteal crease (horizontal gluteal fold), and between the midaxillary lines on both sides, which may be accompanied by pain in one or both lower extremities.\n2. Has moderate to severe pain, with a Visual Analog Scale (VAS) score \\> 4 points.\n3. Aged between 18 and 65 years old.\n4. Has a clear understanding of the study content, good compliance, and high willingness to cooperate.\n5. Has signed a written informed consent form voluntarily.\n\nExclusion Criteria:\n\n1. Is in the acute pain phase or acute exacerbation of chronic pain.\n2. Has low back pain caused by other reasons such as infectious diseases or tumors, including but not limited to spinal tumors, spinal tuberculosis, spinal cord infections, etc.\n3. Has a history of allergy to sodium aescinate.\n4. Suffers from systemic diseases or organ dysfunction.\n5. Has participated in other clinical trials within 1 month before enrollment.\n6. Has severe mental illness or other conditions that prevent cooperation with the study.\n7. Is a pregnant or lactating woman, or a woman planning to become pregnant.\n8. Has metal implants or other conditions that are not suitable for MRI examination.\n9. Is considered by the researcher to have conditions that are unfavorable for completing the study course.",{"count":55,"type":21},40,[57],"PHASE1","The goal of this clinical trial is to assess the clinical efficacy and safety of sodium aescinate in treating low back pain (LBP) in adult participants.",[60,61,62,27],"Low Back Pain","Paraspinal Muscle","CLBP - Chronic Low Back Pain",[29,64,65,62],"sodium aescinate tablets","double-blind randomized controlled trial","RECRUITING","2026-03-19",{"date":69,"type":38},"2026-03-20",{"date":71,"type":38},"2026-03-01",{"date":73,"type":21},"2029-09-01",{"name":75,"class":76},"Xijing Hospital","OTHER",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":99,"leadSponsor":101,"locationsCount":46},"100629104","dynamic-lumbar-strengthening-exercises-versus-pilates-combined-with-myofascial-release-in-non-specific-chronic-low-back-pain-100629104","NCT07470307","Dynamic Lumbar Strengthening Exercises Versus Pilates, Combined With Myofascial Release in Non Specific Chronic Low Back Pain","Inclusion Criteria:\n\nMale and female aged between 25 to 35 years. History of persistent low back pain for more than 3 months. Pain intensity with a score \\> 3 on the Visual Analog Scale (VAS). Functional disability measured by the Oswestry Disability Index (ODI), with scores ranging from 20% to 60%\n\nExclusion Criteria:\n\nIndividuals with acute or subacute low back pain. Presence of systemic illnesses or specific spinal pathologies. Psychological disorders such as severe anxiety or depression affecting participation.","25 Years","35 Years",{"count":86,"type":21},60,[24],"This randomized controlled trial aims to compare the effectiveness of dynamic lumbar strengthening exercises combined with myofascial release versus Pilates combined with myofascial release in individuals with non-specific chronic low back pain.\n\nNon-specific chronic low back pain is one of the most common musculoskeletal disorders affecting adults and is associated with pain, reduced spinal mobility, and functional disability. Exercise-based rehabilitation programs and manual therapy techniques are commonly used to improve functional outcomes in these patients. Dynamic lumbar strengthening exercises focus on improving spinal stability and strengthening trunk musculature, whereas Pilates exercises emphasize core muscle activation, postural control, and controlled movement patterns. Myofascial release is a manual therapy technique used to reduce fascial restrictions, improve soft tissue mobility, and decrease pain.\n\nIn this randomized controlled trial, a total of 60 participants aged between 25 and 35 years with non-specific chronic low back pain lasting more than three months will be recruited from the Physiotherapy Department of the University of Lahore Teaching Hospital. Participants will be randomly allocated into two groups. Group A will receive dynamic lumbar strengthening exercises combined with myofascial release, while Group B will receive Pilates exercises combined with myofascial release.\n\nBoth groups will also receive baseline therapy consisting of therapeutic massage, interferential therapy, and therapeutic ultrasound applied to the lumbosacral region. The exercise programs will be conducted for eight weeks on alternate days, with each session lasting approximately 20-25 minutes.\n\nOutcome measures will include pain intensity assessed using the Visual Analog Scale (VAS), functional disability measured using the Oswestry Disability Index (ODI), and lumbar range of motion measured using an inclinometer. Assessments will be conducted at baseline before the intervention and after completion of the 8-week intervention period.\n\nThe findings of this study will help determine which exercise approach combined with myofascial release is more effective in reducing pain, improving functional disability, and enhancing spinal mobility in individuals with non-specific chronic low back pain. The results may contribute to evidence-based physiotherapy management and improve rehabilitation strategies for patients with chronic low back pain.",[27],[91,92,93,94],"Non-specific chronic low back pain","Lumbar strengthening exercises","Dynamic lumbar stabilization","Pilates exercises","2026-03-15",{"date":97,"type":38},"2026-03-17",{"date":67,"type":21},{"date":100,"type":21},"2026-05-20",{"name":102,"class":76},"Maheen Rauf",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":4},"100614104","interoceptive-awareness-physical-activity-body-awareness-and-emotional-status-in-individuals-with-non-specific-chronic-low-back-pain-100614104","NCT07275255","Interoceptive Awareness, Physical Activity, Body Awareness and Emotional Status in Individuals With Non-Specific Chronic Low Back Pain","Non-Specific Chronic Low Back Pain: Investigation of Interoceptive Awareness, Physical Activity Level, Body Awareness and Emotional Status in Individuals With Non-Specific Chronic Low Back Pain","NSCLBP-AWARE","Inclusion Criteria:\n\n* Adults aged 18-65 years.\n* Diagnosed with non-specific chronic low back pain.\n* Duration of pain ≥ 3 months.\n* Self-reported average pain score ≥ 4\u002F10 on the Visual Analog Scale.\n* Ability to understand and complete self-report questionnaires.\n\nExclusion Criteria:\n\n* Low back pain due to specific pathologies (e.g., tumor, infection, fracture, inflammatory disease).\n* Serious systemic, neurological, or psychiatric comorbidities.\n* History of spinal surgery within the past year.\n* Pregnancy.\n* Language or cognitive impairments preventing questionnaire completion.",{"count":112,"type":21},130,"OBSERVATIONAL","This observational cross-sectional study aims to examine the relationships between interoceptive awareness, physical activity level, body awareness, emotional status, and pain intensity in individuals with non-specific chronic low back pain. Non-specific chronic low back pain refers to pain in the lumbar region lasting for at least three months without an identifiable structural or pathological cause.\n\nParticipants aged 18-65 years who meet the diagnostic criteria for non-specific chronic low back pain will be evaluated using validated self-report questionnaires. These include measures of interoceptive awareness, body awareness, alexithymia, physical activity level, and pain intensity. Sociodemographic and clinical characteristics such as age, gender, education level, duration of pain, medication use, height, weight, and BMI will also be collected.\n\nThe purpose of the study is to better understand how internal body perception, physical activity, emotional processing, and body awareness interact with pain experience in this population. Findings may contribute to the development of individualized rehabilitation programs and inform clinicians about the multidimensional factors influencing chronic low back pain.",[116,117],"Lower Back Pain Chronic","Non Specific Chronic Low Back Pain",[119,120,27,121,122,123],"Interoceptive Awareness","Body Awareness","Chronic Low Back Pain","Alexithymia","Physical Activity","2025-12-15",{"date":126,"type":38},"2025-12-16",{"date":128,"type":21},"2026-01-01",{"date":130,"type":21},"2026-09-01",{"name":132,"class":76},"Istinye University",{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":139,"sex":16,"minAge":83,"maxAge":18,"enrollmentInfo":140,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":142,"conditions":143,"keywords":144,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":154,"leadSponsor":155,"locationsCount":46},"100615713","the-effect-of-body-awareness-on-pain-disability-sensorimotor-acuity-psychosocial-and-central-sensitization-levels-in-individuals-with-non-specific-chronic-low-back-pain-100615713","NCT07296185","The Effect of Body Awareness on Pain, Disability, Sensorimotor Acuity, Psychosocial and Central Sensitization Levels in Individuals With Non-Specific Chronic Low Back Pain","Inclusion criteria are as follows:\n\n* Eligible participants were defined according to the National Institute of Health Task Force for Research Standards for Chronic Pain (RTF). The RTF defines chronic pain as a pain problem that has persisted for at least 3 months and has been present on at least half of the days in the past 6 months. Following these guidelines, two questions will be used to determine chronicity:\n\n  1. \"How long has the pain been an ongoing problem for you?\"\n  2. \"How often has pain been an ongoing problem for you over the past 6 months?\" A response of \"greater than 3 months\" to question 1 and \"at least half the days in the past 6 months\" to question 2 indicated chronic pain.\n* Being 25 and 65 years of age and having no spinal fractures or acute disc herniation;\n* Non-specific chronic low back group for pain a current VAS pain rating ≥4\u002F10; and scoring at least 4 points on the Roland-Morris Disability Questionnaire (RMDQ),\n* Having pain that does not correspond to specific anatomical structures and is widespread;\n* Having no current psychiatric disorders or cognitive impairments and cognitive level sufficient to complete the interview and questionnaires;\n* For the healthy group; Absence of low back pain during the past six months, no history of chronic pain lasting ≥3 months in any body region, having a Visual Analog Scale (VAS) score of VAS ≤1, which having a Roland Morris Disability Questionnaire (RMDQ) score of RMDQ ≤4;\n* Having no history of spinal surgery.\n\nExclusion criteria are as follows:\n\n* The current use of tranquilizers or opioids, any visual or motor impairments (including dyslexia) or presentation with any neurological disease or significant mental illness;\n* Potential subjects if they have nerve symptoms below the knee;\n* Diagnosed chronic fatigue syndrome, fibromyalgia, or other chronic widespread pain syndromes.\n* Severe comorbidities such as neurological disorders, cardiovascular diseases, or rheumatologic conditions.\n* Patients who had undergone spinal surgery, had any illness, or received any treatment that could cause harm were excluded;\n* Having a diagnosis of lumbar radiculopathy;\n* Tumors or infections;\n* Pain arising from metastasis, osteoporosis, inflammatory arthritis, or fractures;\n* Specific medical conditions (such as neck or back surgery within the last 3 years, osteoporotic vertebral fractures);\n* Receiving any other treatment for chronic non-specific low back pain during the study period.",true,{"count":141,"type":21},82,"This study will be conducted to examine the levels of pain, pressure pain threshold, joint position sense, sensation, functionality, pain catastrophizing, central sensitization, and body awareness in individuals with non-specific chronic low back pain, and to compare these findings with those of healthy individuals. Additionally, the study will aim to objectively investigate the relationships between lumbar self-perception (FreBAQ) and tactile acuity (TPDT), pressure pain threshold (PPT), lumbar joint position sense (LJPS), as well as psychosocial (PCS) and central sensitization (CSI) indicators in individuals with non-specific chronic low back pain. Furthermore, the study will seek to evaluate the predictive effects of lumbar self-perception on pain (VAS) and disability (RMDQ), in conjunction with objectively assessed sensory and sensorimotor measures in individuals with non-specific chronic low back pain.",[27],[145,146,147,148,27,149],"Body awareness","Central sensitization","Sensorimotor Acuity","Disability","Psychosocial Factor","2025-12-08",{"date":152,"type":38},"2025-12-22",{"date":128,"type":21},{"date":95,"type":21},{"name":156,"class":76},"Medipol University",{"id":158,"slug":159,"hasResults":11,"nctId":160,"briefTitle":161,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":11,"sex":16,"minAge":164,"maxAge":165,"enrollmentInfo":166,"targetDuration":4,"studyType":22,"phases":168,"briefSummary":169,"conditions":170,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":46},"100609492","comparative-study-on-snag-from-different-positions-low-back-pain-treatment-100609492","NCT07215286","Comparative Study on SNAG From Different Positions Low Back Pain Treatment","Comparative Study on SNAG From Loaded and Unloaded Position in the Treatment of Low Back Pain","Inclusion Criteria:\n\n* Chronic non specific low back pain for 6 weeks or more\n* Who scored between three and six on a visual analogue scale (VAS)\n* Restriction of the movement was only in flexion ROM\n\nExclusion Criteria:\n\n* Pregnancy,\n* Obese,\n* Infectious conditions of the spine,\n* Autoimmune disorders,\n* Malignancy\n* Any contraindication to physiotherapy and manual therapy\n* Any patient received physical therapy sessions last 6 months","20 Years","40 Years",{"count":167,"type":21},34,[24],"Background: Low back pain (LBP) is a leading cause of disability worldwide. Mulligan's Sustained Natural Apophyseal Glides (SNAGs) are manual therapy techniques shown to reduce pain and improve function in LBP. However, whether applying SNAGs in loaded (weight-bearing) versus unloaded (non-weight-bearing) positions yields superior clinical outcomes remains unclear.\n\nObjective: To compare the effects of lumbar SNAGs applied in loaded versus unloaded positions on pain, disability, and function in individuals with chronic non-specific LBP.\n\nMethods: A randomized, single-blind, parallel-group clinical trial will recruit 34 participants with chronic LBP. Participants will be allocated to receive SNAGs in either loaded or unloaded positions, combined with a standardized exercise program, for 6 sessions over 1 week. The primary outcome is pain intensity (Numeric Pain Rating Scale) and lumbar flexion range of motion. Secondary outcomes include disability (Oswestry Disability Index). Outcomes will be measured at baseline and immediately post-treatment. Data will be analyzed using linear mixed models on an intention-to-treat basis.\n\nConclusion: This trial will determine whether a loaded SNAG application provides superior benefits compared to unloaded SNAG in the treatment of chronic LBP. Findings may guide clinical decision-making and optimize manual therapy application.",[117],"2025-10-02",{"date":173,"type":38},"2025-10-10",{"date":175,"type":21},"2025-10-15",{"date":177,"type":21},"2026-01-15",{"name":179,"class":76},"University of Hail",{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":186,"eligibilityCriteria":187,"healthyVolunteers":139,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":188,"targetDuration":4,"studyType":22,"phases":189,"briefSummary":190,"conditions":191,"keywords":193,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":46},"100606997","effects-of-multifidus-lift-exercise-on-endurance-pain-and-disability-in-university-students-with-low-back-pain-100606997","NCT07182825","Effects of Multifidus Lift Exercise on Endurance, Pain, and Disability in University Students With Low Back Pain","Evaluation of the Effects of Multifidus Lift Exercise on Endurance, Pain, and Disability in University Students With Low Back Pain","LBP-MULEX","Inclusion Criteria:\n\n* Age between 18 and 25 years\n\nCurrently enrolled as a university student at Selçuk University\n\nWilling to participate voluntarily and sign informed consent form\n\nMedically suitable for exercise participation\n\nFor NSCLBP group:\n\nHistory of nonspecific chronic low back pain within the past 3 months\n\nPhysician confirmation of nonspecific low back pain\n\nOswestry Disability Index (ODI) ≥ 21% (moderate disability)\n\nVisual Analog Scale (VAS) score ≥ 3.5\n\nFor Healthy control group:\n\nNo history of low back pain within the past 3 months\n\nPhysician confirmation of no contraindications for exercise\n\nExclusion Criteria:\n\n* Presence of radicular pain or nerve root compression symptoms\n\nHistory of spinal surgery\n\nNeurological deficits within the past 3 months (e.g., muscle weakness, reflex loss, paresthesia)\n\nSystemic infection or systemic disease affecting participation\n\nCardiovascular or pulmonary disease contraindicating exercise\n\nClinical \"red flag\" symptoms (e.g., saddle anesthesia, bowel\u002Fbladder incontinence, fever, known cancer)\n\nPregnancy\n\nRegular use of analgesics, muscle relaxants, or anti-inflammatory medications\n\nParticipation in regular exercise programs in the past 3 months\n\nActive involvement in sports directly affecting lumbar muscles (e.g., fitness, pilates, yoga, swimming)\n\nInability to comply with exercise sessions or study protocol",{"count":55,"type":21},[24],"Nonspecific low back pain is a common musculoskeletal problem that also affects many young adults, including university students. It can negatively impact academic performance, daily life, and overall well-being. Research shows that stabilization exercises targeting the lumbar multifidus muscle play an important role in rehabilitation, but it is unclear whether modified versions of these exercises may provide additional benefits.\n\nThis study will investigate a simple modification of the traditional \"bird-dog\" exercise, called the \"Multifidus Lift Exercise.\" In this version, participants maintain the contralateral knee about 10 cm above the ground while in a four-point kneeling position. This adjustment is expected to increase multifidus activation and improve back endurance.\n\nUniversity students aged 18-25 with nonspecific low back pain will participate in a 6-week supervised program, performing the exercise twice weekly. A healthy control group without low back pain will also be included. The main outcome will be back extensor muscle endurance (Biering-Sørensen Test). In participants with back pain, pain intensity (Visual Analog Scale) and functional disability (Oswestry Disability Index) will also be measured.\n\nThe study aims to determine whether this low-cost, practical, and time-efficient exercise can improve muscle endurance, reduce pain, and decrease disability in young adults with low back pain. Results may provide evidence for an effective and accessible preventive and therapeutic approach in student populations.",[60,117,192],"Healthy Vollunteer",[194,195,196,197,198,199,200,148,201,202,203,204,205,206],"Nonspecific Low Back Pain","Multifidus Muscle","Multifidus Lift Exercise","Bird-Dog Exercise (Modified)","Spinal Stabilization Exercise","Endurance","Pain","Oswestry Disability Index (ODI)","Visual Analog Scale (VAS)","Biering-Sørensen Test","University Students","Young Adults","Healthy Controls","2025-09-14",{"date":209,"type":38},"2025-09-19",{"date":211,"type":21},"2025-10-01",{"date":213,"type":21},"2026-02-28",{"name":215,"class":76},"Mehmet Akif Guler",{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":223,"targetDuration":4,"studyType":22,"phases":224,"briefSummary":225,"conditions":226,"keywords":229,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":46},"100569596","effects-of-foundation-and-functional-inspiratory-muscle-training-in-non-specific-chronic-low-back-pain-100569596","NCT06696300","Effects of Foundation and Functional Inspiratory Muscle Training in Non-Specific Chronic Low Back Pain","Comparison of the Effects of Foundation and Functional Inspiratory Muscle Training in Addition to Classical Physiotherapy in Non-Specific Chronic Low Back Pain","Inclusion Criteria:\n\n* Volunteering to participate in the study,\n* Being between the ages of 18-65,\n* Having low back pain that has been ongoing for at least 3 months (12 weeks),\n* Having a Visual Analog Scale (VAS) of pain intensity of ≥3,\n* Being right-hand dominant.\n\nExclusion Criteria:\n\n* Not volunteering to participate in the study,\n* Having a history of cancer,\n* Having a spinal infection,\n* Having a rheumatological condition,\n* Having a spinal fracture,\n* Having red flag signs (sudden and unexpected weight loss, fever, etc.)\n* Having a psychological disorder,\n* Having a previous spinal surgery,\n* Having radiculopathy (neuropathic pain along the lower extremity due to nerve root compression),\n* Not continuing home exercises more than 80%,\n* Having an anatomical and congenital abnormality",{"count":86,"type":21},[24],"This study was planned to examine the effects of basic and functional respiratory muscle training on pain, disability level, and functionality. In this study, participants will be randomly divided into 3 groups. The first group will be treated with physical therapy applications applied in state hospitals for 10 weeks. The second group will receive basic respiratory muscle training treatment in addition to physical therapy in state hospitals. The third group will receive respiratory muscle training with exercise in addition to physical therapy in state hospitals. Evaluations will be made before the first session, after the 30th session, in the 3rd month, in the 6th month, and in the 1st year. There is no interventional method in the evaluations. Pain intensity, disability level, physical activity status, quality of life, fear of movement, pain catastrophizing, anxiety and depression levels will be questioned with scales. In physical measurements, participant's aerobic capacity will be measured with the 2-Minute Walk Test, participants's flexibility with the sit-and-long test, participants's respiratory muscle strength with the MIP\u002FMEP device, participants's core endurance with the trunk flexor muscle endurance test, participants's lower and upper extremity muscle strength with a handheld dynamometer, participants's postural control with the Biodex balance device, and participants's muscle thickness with an ultrasound.",[227,228,117],"Low Back Pain, Mechanical","Low Back Pain, Chronic",[60,230,231,232,233],"Respiratory Muscle Strength","Muscle Training","Classical Physiotherapy","Ultrasound","2024-12-29",{"date":236,"type":38},"2024-12-31",{"date":238,"type":38},"2024-12-15",{"date":240,"type":21},"2026-12-01",{"name":242,"class":76},"Kirsehir Ahi Evran Universitesi",{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":249,"enrollmentInfo":250,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":251,"conditions":252,"keywords":254,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":4},"100571151","influence-of-gender-difference-on-knee-proprioception-in-non-specific-low-back-pain-among-young-adults-100571151","NCT06716515","Influence of Gender Difference on Knee Proprioception in Non-Specific Low Back Pain Among Young Adults","Inclusion Criteria:\n\n1. Forty-one Patients from each gender participated in the study.\n2. Subject's age ranged from 18-26 years old, with Body Mass Index (BMI) less than 30Kg\u002Fm2\n3. The dominant knees of the subjects (defined as the leg used for kicking) are tested.\n4. Pain between three and eight using numerical pain rating scale NPRS, and Oswestry Disability Index score less than 20.\n5. All the subjects sign an informed consent form. 6. able to comprehend and follow the examiner's instructions.\n\nExclusion Criteria:\n\n1. limitation of active and passive knee joint motion.\n2. clinical signs of an impairment or abnormality in the knee (such as abnormal range of motion, muscle weakness, or malalignment).\n3. injury to the knee that required medical attention.\n4. current pain in the knee or previous surgery on the knee.\n5. not able to understand and follow the commands of the examiner.","26 Years",{"count":141,"type":21},"the aim of the study is to investigate the impact of gender difference on knee proprioception among non specific low back pain young adults.",[253],"Non-Specific Chronic Low-back Pain",[255,256,257],"Gender Difference","Knee Proprioception","Chronic Non-Specific Low-back Pain","2024-12-03",{"date":260,"type":38},"2024-12-05",{"date":262,"type":21},"2024-12-01",{"date":264,"type":21},"2025-02-15",{"name":266,"class":76},"Cairo University"]