[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"noncommunicable-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:noncommunicable-diseases":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,94,119,143,167,223],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":51,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":93},"100469557","generation-victoria-cohort-2020s-a-statewide-longitudinal-cohort-study-of-victorian-children-and-their-parents-100469557",false,"NCT05394363","Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents","Generation Victoria Cohort 2020s. A Statewide Longitudinal Cohort of Victorian Children and Their Parents","GenV","Inclusion Criteria (Children):\n\n* Birth date between 4th October 2021 and 3rd October 2023\n* Live at the time of recruitment\n* Residing in Victoria at the time of recruitment\n* Has a legally acceptable representative capable of understanding the informed consent document and providing consent on the child's behalf, who provides a signed and dated informed consent form (e.g. a parent\u002Fguardian)\n\nInclusion Criteria (Adults):\n\n* Be a parent or guardian of a child who meets the eligibility criteria above\n* Provide a signed and dated informed consent form or have a legally acceptable representative capable of understanding the informed consent document and providing consent on the participant's behalf.\n\nExclusion criteria:\n\n* Children who are deceased at the time of recruitment (i.e. still born or died after birth) and their parents\u002Fguardians\n* Families unable to provide informed consent in any of the languages available",true,"ALL","1 Day",{"count":21,"type":22},150000,"ESTIMATED","OBSERVATIONAL","Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes. GenV blends study-collected, study-enhanced and linked data. It will be multi-purpose, supporting observational, interventional, health services and policy research within the same cohort. It is designed to address physical, mental and social issues experienced during childhood, as well as the antecedents of a wide range of diseases of ageing. It seeks to generate translatable evidence (prediction, prevention, treatments, services) to improve future wellbeing and reduce the future disease burden of children and adults.\n\nThe GenV Cohort 2020s is open to all children born over a two-year period, and their parents, residing in the state of Victoria Australia. The GenV Cohort 2020s is preceded by an Advance Cohort of children born between 5 Dec 2020 and 3 October 2021, and their parents. This comprises all families recruited at GenV's Vanguard hospital (Joan Kirner Women's and Children's) and at birthing hospitals throughout Victoria as GenV scaled up to commence recruiting for the GenV Cohort 2020s. The Advance Cohort have ongoing and full participation in GenV for their lifetime unless they withdraw but may have less complete data and biosamples.",[26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50],"Mental Health","Child Wellbeing","Infant Health","Child Health","Reproductive Health","Healthy Aging","Health Equity","Quality of Life","Social Determinants of Health","Environmental Exposure","Genetics","Cognition","Learning","Child Development","Congenital Abnormalities","Disability","Injuries","Communicable Diseases","Noncommunicable Diseases","Physical Fitness","Diet","Obesity","Allergy and Immunology","Inflammation","Intergenerational Relations",[52,15,53,54,55,29,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,32,72,73,74,75,76,77,78,34,79,80],"Generation Victoria","Cohort Studies","Data Collection","Data Linkage","Midlife Health","Children","Infants","Family","Parents","Mothers","Fathers","Life course perspective","Population Health","Longitudinal Studies","Genetics, population","Demography","Epidemiology","Health Disparity","Minority Health","Vulnerable Populations","Clinical Trial","Randomized Controlled Trial","Pragmatic Clinical Trial","Health Services Research","Economic Models","Value of Life","Geographic Information Systems","Climate Change","Built Environment","RECRUITING","2025-07-30",{"date":84,"type":85},"2025-08-03","ACTUAL",{"date":87,"type":85},"2021-10-04",{"date":89,"type":22},"2033-10",{"name":91,"class":92},"Murdoch Childrens Research Institute","OTHER",1,{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":18,"minAge":101,"maxAge":4,"enrollmentInfo":102,"targetDuration":4,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":93},"100587672","uncpm-22322---adaption-of-the-transition-of-care-model-for-post-discharge-hiv-ncd-care-in-lilongwe-malawi---mlatho-100587672","NCT06931431","UNCPM 22322 - Adaption of the Transition of Care Model for Post-Discharge HIV-NCD Care in Lilongwe, Malawi - MLATHO","MLATHO","Inclusion Criteria:\n\n* 18 years of age or older\n* living with HIV\n* admitted to internal medicine\n* has at least a cardiometabolic NCO as the primary or secondary reason for admission based on the HIV inpatient consultation\n\nExclusion Criteria:\n\n* patients living beyond Lilongwe urban","18 Years",{"count":103,"type":22},75,"INTERVENTIONAL",[106],"NA","This is an implementation research study that will adapt and pilot test the Transitional Of Care Model (TCM), originally conceived and developed in the USA, for targeted use as a post-discharge intervention for adults hospitalized with comorbid HIV and NCDs in Malawi using a mixed methods approach.",[109,44],"HIV","2025-06-17",{"date":112,"type":85},"2025-06-18",{"date":114,"type":85},"2025-05-12",{"date":116,"type":22},"2027-03",{"name":118,"class":92},"University of North Carolina, Chapel Hill",{"id":120,"slug":121,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":126,"targetDuration":4,"studyType":104,"phases":128,"briefSummary":129,"conditions":130,"keywords":4,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":142},"100567946","school-based-e-health-non-communicable-disease-ncd-prevention-program-100567946","NCT06674798","School-based e-Health Non-Communicable Disease (NCD) Prevention Program","School-based e-Health Non-Communicable Disease (NCD) Prevention Program to Improve Awareness in Adolescents From Urban Pakistan","Inclusion Criteria:\n\nPhase 1 (FGDs and Interviews)\n\n* Students currently enrolled in secondary and higher secondary schools in Karachi and are in grades 9 to 12.\n* Teachers who have been employed in secondary and higher secondary schools in Karachi for a minimum duration of 6 months.\n* Parents or legal guardians of students who are currently enrolled in secondary and higher secondary schools in Karachi.\n* Principals and vice principals of secondary and higher secondary schools in Karachi, District Education Officers, and decision-makers at Provincial Department of Education.\n\nPhase 2 (Intervention)\n\n\\- Both study and control group would be selected from secondary schools (students in grades 9-10) and Higher Secondary Schools (students in grades 11-12) located in Karachi, Pakistan\n\nPhase 3 (FGDs) - Participants from grades 9 to 12 of the secondary and higher secondary schools who actively participated in the intervention and attended all the health-promoting sessions (equal representation of male and female)\n\nExclusion Criteria:\n\n\\- Schools outside Karachi",{"count":127,"type":22},272,[106],"The goal of this sequential mixed method study is to assess the feasibility and effectiveness of a school-based eHealth-NCD prevention program intervention to improve adolescents' knowledge, attitude, and practices regarding NCDs and associated risk factors. It aims :\n\n1. To identify barriers and facilitators associated with implementing a school-based eHealth intervention to improve the knowledge, attitudes, and practices of secondary and higher secondary school students in Pakistan regarding NCDs and their associated risk factors.\n2. To explore the stakeholders' perceptions regarding the design and content of the School based eHealth NCD prevention Program to improve the knowledge, attitudes, and practices of secondary and higher secondary school students in Pakistan regarding NCDs and their associated risk factors.\n3. To assess the feasibility and effectiveness of the School-based eHealth NCD prevention program in secondary and higher secondary school in Karachi.\n4. To evaluate the effectiveness of the school-based eHealth NCD prevention program in significantly improving the knowledge, attitudes, and practices of secondary and higher secondary school students in Karachi, Pakistan, regarding NCDs and their associated risk factors, as compared to a control group not receiving the intervention.\n5. To explore the perceptions of students regarding the usefulness acceptability and task technology fit of the School-based eHealth NCD prevention Program in improving the knowledge, attitude, and practices of Pakistani Higher Secondary School students regarding NCDs and their associated risk factors.\n\nResearcher aim to evaluate the effectiveness of the school-based eHealth NCD prevention program in significantly improving the knowledge, attitudes, and practices of secondary and higher secondary school students in Karachi, Pakistan, regarding NCDs and their associated risk factors, as compared to a control group not receiving the intervention.\n\nParticipants of intervention group will attend health-promoting sessions delivered by trained facilitators, with each session lasting 30 to 40 minutes. There will be a total of six health-promoting sessions be focused on the leading risk factors associated with NCDs as reported by different studies such as physical inactivity, unhealthy diet and overweight, obesity, harmful alcohol consumption and tobacco use will be conducted in the classroom for the intervention group.",[44,131,132],"Health Knowledge, Attitudes, Practice","Non-communicable Disease Risk Factors","2024-11-04",{"date":135,"type":85},"2024-11-05",{"date":137,"type":85},"2024-03-01",{"date":139,"type":22},"2025-03",{"name":141,"class":92},"Aga Khan University",7,{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":147,"acronym":148,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":150,"targetDuration":152,"studyType":23,"phases":4,"briefSummary":153,"conditions":154,"keywords":4,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":93},"100243993","vicente-ferrer-hiv-cohort-study-100243993","NCT02454569","Vicente Ferrer HIV Cohort Study","VFHCS","Inclusion Criteria:\n\n* Positive serology for HIV\n\nExclusion Criteria:\n\n* Refuse to consent",{"count":151,"type":22},30000,"30 Years","The VFHCS is a long-term prospective cohort study of HIV infected patients from a resource-poor rural setting in India. The aim of the study is to use data collected from routine clinical care in order to describe the epidemiology of HIV and its related conditions in the investigators area, and to study the effectiveness of health interventions in a \"real-world\" setting (implementation and operational research).",[109,155,156,157,44],"Tuberculosis","Cryptococcosis","Opportunistic Infections","2023-03-28",{"date":160,"type":85},"2023-03-29",{"date":162,"type":4},"2009-09",{"date":164,"type":22},"2040-01",{"name":166,"class":92},"Rural Development Trust Hospital",{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":173,"eligibilityCriteria":174,"healthyVolunteers":17,"sex":175,"minAge":101,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":104,"phases":179,"briefSummary":180,"conditions":181,"keywords":198,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":93},"100439987","hiit-vs-mict-during-pregnancy-and-health-and-birth-outcomes-in-mothers-and-children-100439987","NCT05009433","HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children","The Effect of Pre- and Postnatal High Intensity Interval Training and Moderate Intensity Continuous Training on Biological, Functional and Psychological Markers of Pregnancy Disorders and Non-communicable Diseases in Mothers and Offsprings","HIIT MAMA","Inclusion Criteria:\n\nCriteria: Inclusion Criteria:\n\nFor pregnant women:\n\n1. course of pregnancy allowing participation in physical activities adapted to pregnant women\n2. consent of the obstetric care provider to participate in the study tests and exercise classes;\n3. taking part in all diagnostic and control tests to assess selected biological, functional and psychological parameters at each trimester of pregnancy, during the puerperium and one year after childbirth;\n4. participant's consent to use data from the medical documentation on the course of childbirth and the assessment of the new-born, as well as the results of preventive examinations in children aged one, two, four and six, routinely performed according to the Polish pediatric care system;\n5. availability to participate in classes three times a week until the day of delivery;\n6. declaration of participation in postpartum classes at least once a week and self-completion of the exercise program according to written instructions prepared by the exercise specialist;\n7. women can participate in the exercise programs regardless of their level of fitness or exercise capacity, as well as the level of motor skills (based on the diagnostic exercise tests, the exercise program will be tailored to the individual needs and capabilities of a woman).\n\nFor nonpregnant women:\n\n1. nulliparous;\n2. lack of diagnosed infertility and other disorders of the reproductive system;\n3. taking part in all diagnostic and control tests to assess selected biological, functional and psychological parameters at indicated time points: before and after each of the 8-week exercise program during the first 8 months of the study and once every 3 months during the following twelve months of the study\n4. declaration of availability to participate in exercise classes three times a week for the first 8 months of the program (attendance at least 80% is required);\n5. declaration of participation in classes at least once a week and self-completion of the exercise program to the required 150 minutes of physical activity per week, according to the written guidelines prepared by the instructor, for the next 12 months of the program;\n6. women can participate in the exercise program regardless of their level of fitness or exercise capacity, as well as the level of motor skills (based on the diagnostic exercise tests, the exercise program will be tailored to the individual needs and capabilities of a woman).\n\nExclusion Criteria for Pregnant and Nonpregnant Women:\n\n1. contraindications to increased physical effort or to any of the diagnostic or control tests;\n2. allergies to materials used during diagnostic and control tests (e.g. nickel present in steel plates of vaginal electrodes, disinfectants);\n3. other conditions that, according to the researchers, will threaten the health or safety of the participants or will significantly affect the quality of the collected data.","FEMALE","45 Years",{"count":178,"type":22},600,[106],"Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior. Physically active pregnant women significantly less often suffer from, among others, gestational diabetes, excessive weight gain, lipids disorders, hypertension, preeclampsia, depressive symptoms, functional and structural disorders, including stress urinary incontinence, back pain or diastasis recti abdominis (DRA). Prenatal physical activity reduces the risk of premature delivery and miscarriage, fetal macrosomia, complications in labor or the risk of metabolic disorders in children.\n\nHigh-intensity interval training (HIIT) has become one of the most popular trends in the fitness sector. The effectiveness of HIIT on a number of health indicators has been proven in various populations but limited data are available on HIIT during pregnancy.\n\nThe first hypothesis is that the HIIT, implemented during pregnancy and after childbirth, as a stronger exercise stimulus, will have a better impact on selected biological and psychological parameters of mothers, as well as on selected health parameters of their children, compared to the MICT (moderate intensity continuous training). Therefore, it promises better preventive effects on pregnancy complications and ailments as well as non-communicable diseases occurring in these populations. In the second hypothesis, it was assumed that HIIT and MICT implemented during pregnancy and after childbirth, tailored to the specific needs of the perinatal period, will not differ in the effectiveness of maintaining normal functional parameters in women, including prevention of urinary incontinence, back pain, DRA, etc.\n\nPregnant women who apply for the study will be divided into three groups: those attending the HIIT, MICT or educational programs. During the study, the participants will be under standard obstetric care. As comparative groups, non-pregnant women will be also recruited.\n\nThe investigators will collect data on selected biological, functional and psychological parameters in the study women at each trimester of pregnancy, during the puerperium and one year after childbirth. The data from the medical documentation on the course of childbirth and the assessment of the new-born, as well as the results of preventive examinations in the study women's children aged one, two, four and six years will be also analyzed.",[182,183,184,185,45,44,186,187,188,189,190,191,192,193,194,195,196,197],"Pregnancy","Postpartum","Childbirth","Health Status","Metabolism","Diabetes Mellitus, Gestational","Pregnancy Induced Hypertension","Body Composition","Back Pain","Pain Threshold","Biomechanics","Pelvic Floor Disorders","Urinary Incontinence","Cognitive Function","Depression","Anxiety",[199,200,201,202,203,204,205,206,207,208,209,185,210,184,211,212,213],"Pregnant women","Prenatal care","Postpartum women","Postnatal care","Exercise","Physical activity","Exercise intervention","Educational intervention","Exercise test","High-intensity interval training","Moderate-intensity continuous training","Physical fitness","Birth outcomes","Infant","Child","2022-11-30",{"date":216,"type":85},"2022-12-02",{"date":218,"type":85},"2021-06-24",{"date":220,"type":22},"2031-08-31",{"name":222,"class":92},"Gdansk University of Physical Education and Sport",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":18,"minAge":101,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":232,"conditions":233,"keywords":240,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":93},"100458345","the-long-term-spill-over-impact-of-covid-19-on-health-and-healthcare-of-people-with-non-communicable-diseases-100458345","NCT05248412","The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of People With Non-communicable Diseases","The Long-term Spill-over Impact of COVID-19 on Health and Healthcare of Patients With Non-communicable Diseases (and Without COVID-19) : an In-depth Outcome and Health Economic Evaluation","(For cohort study)\n\nInclusion Criteria:\n\n* People aged 18 years or above with a documented doctor-diagnosed NCDs (diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic kidney disease, or chronic respiratory disease )\n* People who attended at least once HA hospitals, general or specialist out-patients clinics between 1 January 2010 and 31 December 2024\n\nExclusion Criteria:\n\n\\- People with a documented doctor-diagnosed COVID-19\n\n(For cross-sectional study)\n\nInclusion Criteria:\n\n* People aged 18 years or above with a documented doctor-diagnosed NCDs (diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic kidney disease, or chronic respiratory disease )\n* All participants are able to communicate in either Chinese or English and provide informed consent.\n\nExclusion Criteria:\n\n* People with a documented diagnosis of COVID-19 during the study period.",{"count":231,"type":22},250000,"Objectives and aim: To evaluate the long-term spill-over (indirect) effect of Coronavirus disease (COVID-19) on health outcomes and healthcare utilization among people with non-communicable diseases and without COVID-19.\n\nDesign: A population-based cohort study using electronic health records of the Hospital Authority (HA) clinical management system, economic modeling, and serial cross-sectional surveys on healthcare service utilization.\n\nSetting: HA public hospitals and outpatient clinics in Hong Kong\n\nParticipants: People aged ≥ 18 years with a documented diagnosis of diabetes mellitus, hypertension, cardiovascular disease, cancer, chronic respiratory disease, and chronic kidney disease; without COVID-19; attending HA services between 2010 and 2024.\n\nMain outcome measures: All-cause mortality, disease-specific outcomes, healthcare service utilization, and costs.\n\nMethods: The annual incidence of each outcome in each year between 2010 and 2024 will be calculated. An interrupted time-series analysis to assess the changes in outcomes between pre-and-post-COVID-19 outbreak periods. Long term health economic impact of healthcare disruptions during the COVID-19 outbreak will be modeled using microsimulation. Multivariable Cox proportional hazards regression and Poisson\u002Fnegative binomial regression to evaluate the effect of different modes of care on the risk of the outcomes.\n\nImplications: Findings will inform policies and practices on contingency care plans to avoid excessive morbidity and mortality and to assure the quality of care for patients with NCD as part of the territorial response to the health crisis.",[234,235,236,237,238,239,44],"Diabetes Mellitus","Hypertension","Cancer","Cardiovascular Diseases","Chronic Respiratory Disease","Kidney Disease, Chronic",[241,242,243,244,44],"COVID-19 Pandemic","Morality","Complication","Utilization, Health Care","2022-02-20",{"date":247,"type":85},"2022-03-08",{"date":249,"type":85},"2021-06-21",{"date":251,"type":22},"2026-06-30",{"name":253,"class":92},"The University of Hong Kong"]