[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nose-cancer\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nose-cancer":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100644707","functional-and-aesthetic-comparison-of-surgical-nasal-reconstruction-versus-nasal-prosthesis-epithesis-after-total-or-subtotal-nasal-amputation-100644707",false,"NCT07674030","Functional and Aesthetic Comparison of Surgical Nasal Reconstruction Versus Nasal Prosthesis (Epithesis) After Total or Subtotal Nasal Amputation","Comparison of Epithesis and Surgical Nasal Reconstruction Using the SCHNOS Score","CERNAS","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Patients who have undergone total or subtotal nasal amputation (defined as loss of at least three nasal subunits, or of two subunits including the dorsum) and who have been rehabilitated either by surgical reconstruction or by nasal epithesis for more than one year\n\nExclusion Criteria:\n\n* Ongoing tumour progression or tumour recurrence\n* Non-French-speaking patients\n* Patients under legal protection measures (guardianship, legal safeguarding, limited or full legal incapacity)\n* Patients unlikely to cooperate with the study (e.g. presenting with a psychiatric disorder)","ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","OBSERVATIONAL","CERNAS is a prospective, multicenter, non-interventional study comparing the functional and aesthetic outcomes of two rehabilitation strategies after total or subtotal nasal amputation: surgical reconstruction (primarily paramedian forehead flap or free flap) versus nasal epithesis (prosthesis). Patients who have undergone either rehabilitation at least one year prior to enrolment will be invited to complete the validated French version of the SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) questionnaire. The study aims to provide an objective, patient-reported comparison of these two options to guide future clinical decision-making.",[25,26],"Nose Cancer","Rhinectomy",[28,29,30,31,32,33,34,35],"Total rhinectomy","Nasal reconstruction","Nasal prosthesis","SCHNOS","Nasal amputation","Quality of life","Free flap","Forehead flap","NOT_YET_RECRUITING","2026-06-29",{"date":39,"type":40},"2026-07-01","ACTUAL",{"date":39,"type":21},{"date":43,"type":21},"2027-01-30",{"name":45,"class":46},"Hôpital NOVO","OTHER",4,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":66,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":5},"100577829","somesthesia-in-cancer-patients-variability-and-influence-on-eating-experience-100577829","NCT06803381","Somesthesia in Cancer Patients: Variability and Influence on Eating Experience","SOMEST'ALIM2","Inclusion Criteria:\n\n* Patient between 18 and 70 years old\n* Patient with digestive, breast, gynecologic, ENT or lung cancer\n* Patient receiving a cancer treatment from at least two months\n* Patient having given his free, informed and express written consent\n\nExclusion Criteria:\n\n* Patient having a radiotherapy treatment for an ENT cancer\n* Patient with a known food allergy\u002Fintolerance to food samples (which may contain dairy products)\n* Patient unable to swallow soft food\n* Patient having presented nausea and vomiting during the last 24 hours\n* Patient with severe inflammation of the mouth or throat (ulcers, mucus)\n* Patient with cognitive disorders and memory loss\n* Pregnant women or breastfeeding\n* Adult under legal protection (guardianship)","70 Years",{"count":57,"type":21},96,"Patients with cancer are at high risk of denutrition, in France 39% of these patients suffer of malnutrition. This can affect the immunity, the mental balance and impact the treatment response and the quality of life.\n\nCancer treatments cause many side effects related to food intake as well as sensory alteration, important factor contributing to reduced appetite and inadequate food intake to cancer patients.\n\nSOMEST'ALIM2 is a prospective, non-randomized, monocentric, multisite study that aims to evaluate the appreciation of patients with different types of cancer (digestive, gynecological, breast, ear, nose and throat (ENT) or lung) of two different food versions (sweet and salty), in standard and enhanced version.\n\nPatients must be under treatment from at least two months, and before food testing their sensory capacity and quantity and the quality of their saliva will be tested. They will also be asked to answer to different questionnaires: socio-demographics, appreciation of food samples, self-assessment of oral symptoms and sensory perceptions, MD, Quality of Life Questionnaire (QLQ-C30) and food quality of life questionnaire.\n\nIn a context of sensory alterations patients should appreciate more the enhanced food versions. Patients perception of food will be evaluated using a visual analogue scale and results will be correlated with saliva characteristics, subjective sensory perceptions and oral symptoms.",[60,61,62,63,25,64,65],"Digestive Cancers","Breast Cancer","Gynecologic Cancer","Lung Cancer","Throat Cancer","Ear Cancer",[67,68,69,70,71],"Cancer","nutrition","somesthesia","food","perceptions","2025-02-04",{"date":74,"type":40},"2025-02-06",{"date":76,"type":21},"2025-03-13",{"date":78,"type":21},"2025-06-15",{"name":80,"class":46},"Hospices Civils de Lyon"]