[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nuclear-cataract\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nuclear-cataract":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100610152","the-impact-of-physiologic-cataract-surgery-on-patient-comfort-and-medication-usage-100610152",false,"NCT07223866","The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage","Inclusion Criteria: Subjects who will require bilateral cataract surgery will be considered. Evaluations will occur in the clinic of the Principal Investigator (PI) Matthew Rauen, MD at the Wolfe Eye Clinic.\n\nInclusion Criteria:\n\n* Visually significant cataract 2-3+ undergoing uncomplicated cataract surgery with similar cataract grade in both eyes\n* Unremarkable ocular health but inclusive of early AMD\n\nExclusion Criteria:\n\n* H\u002Fo ocular surgery including corneal refractive surgery\n* Compromised zonular integrity or stability\n* Uncontrolled diabetes and diabetic retinopathy\n* Small pupils\n* H\u002Fo systemic inflammatory disease\u002Fuveitis\n* H\u002Fo chronic pain medications (including narcotics) and benzodiazepine usage\n* Abnormal liver or renal function","ALL","60 Years",{"count":18,"type":19},85,"ESTIMATED","INTERVENTIONAL",[22],"NA","The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon. Our hypothesis is that operating at a more physiological IOP using Unity VCS\u002FCS and Centurion with Active Sentry at a higher, or more traditional IOP will result in significantly less discomfort\u002Fpain as assessed by the decreased need for rescue medication and lower VAS scores.",[25,26,27,28],"Cataract and IOL Surgery","Cataract Surgery Anesthesia","Cataract Surgery Experience","Nuclear Cataract","NOT_YET_RECRUITING","2025-11-05",{"date":32,"type":33},"2025-11-10","ACTUAL",{"date":35,"type":19},"2025-11-01",{"date":37,"type":19},"2027-01-01",{"name":39,"class":40},"Matthew Rauen","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":20,"phases":53,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":41},"100594473","minimal-vitrectomy-surgery-for-epiretinal-membrane-100594473","NCT07019896","Minimal Vitrectomy Surgery for Epiretinal Membrane","Minimal Vitrectomy Surgery (MVS) Versus Conventional Vitrectomy for the Treatment of Idiopathic Epiretinal Membrane: A Multicenter Randomized Controlled Trial","MVS-ERM","Inclusion Criteria:\n\n1. Age ≥ 18 years.\n2. Diagnosis of idiopathic epiretinal membrane (ERM) confirmed by clinical examination and OCT imaging.\n3. Clear ocular media allowing adequate fundus imaging.\n4. Phakic eye.\n5. Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n1. Prior cataract surgery or advanced cataract requiring combined surgery. Co-existing retinal diseases (e.g., diabetic retinopathy, retinal detachment, retinal vein occlusion).\n2. Systemic conditions preventing safe surgery or follow-up.\n3. History of prior ocular or periocular corticosteroid use, including intraocular injection, periocular injection, or long-term topical corticosteroid eye drops.","18 Years",{"count":52,"type":19},140,[22],"This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM). The primary endpoints include visual acuity improvement and cataract progression after 12 months. MVS aims to minimize vitreous removal while ensuring complete membrane removal through adaptive limited vitrectomy.",[56,57,28],"Epiretinal Membrane","Macular Edema (ME)",[59,60,61,62],"Idiopathic Epiretinal Membrane (ERM)","Minimal Vitrectomy Surgery (MVS)","Nonvitrectomizing Vitreous Surgery (NVS)","pars plana Vitrectomy (PPV)","RECRUITING","2025-06-05",{"date":66,"type":33},"2025-06-13",{"date":68,"type":33},"2024-12-01",{"date":70,"type":19},"2026-11-30",{"name":72,"class":40},"Peking Union Medical College Hospital"]