[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nutrition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nutrition":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,47,0,25,[9,52,87,109,133,162,186,217,248,276,300,332,367,388,410,431,459,485,511,542,568,591,615,652,685],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100053953","early-time-restricted-eating-combined-with-exercise-in-older-adults-100053953",false,"NCT07695961","Early Time-Restricted Eating Combined With Exercise in Older Adults","Effects of Early Time-Restricted Eating Combined With a Multicomponent Exercise Program on Bone Mineral Density, Gait, Balance, and Fall Risk in Healthy Older Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 60 years or older\n* Community-dwelling and generally healthy older adults\n* Sedentary or moderately physically active\n* Stable body weight during the previous 3 months (no intentional weight loss or gain \\>5%)\n* Able to participate in a supervised exercise program\n* Willing to comply with the time-restricted eating protocol and study procedures\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosis of osteoporosis requiring pharmacological treatment\n* Severe sarcopenia or major mobility limitations preventing safe exercise participation\n* Cognitive impairment or diagnosed dementia affecting ability to follow instructions\n* Presence of uncontrolled chronic diseases affecting bone metabolism (e.g., advanced renal disease, uncontrolled endocrine disorders)\n* Current use of medications affecting bone metabolism (e.g., corticosteroids, anti-osteoporotic drugs)\n* Participation in another structured exercise or dietary intervention program within the past 3 months\n* Any medical condition that contraindicates moderate-intensity exercise\n* Inability to comply with study protocol or follow-up assessments",true,"ALL","60 Years","85 Years",{"count":22,"type":23},44,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized controlled trial aims to investigate the effects of Early Time-Restricted Eating (eTRE) combined with a multicomponent exercise program on bone health, physical function, and fall risk in healthy older adults.\n\nA total of approximately 44 healthy adults aged 60 years and older will be recruited and randomly assigned to one of two groups. The experimental group will follow an Early Time-Restricted Eating schedule combined with a structured multicomponent exercise program. The control group will not receive any dietary timing intervention or structured exercise program and will continue their usual daily lifestyle.\n\nThe intervention will last for 6 months. Participants in the exercise program will perform supervised sessions including resistance training, balance exercises, aerobic activity, and flexibility exercises. The Early Time-Restricted Eating protocol will involve consuming all daily food intake within an early daytime window while maintaining usual dietary quality and adequate energy and nutrient intake.\n\nThe main outcomes of the study include changes in bone mineral density, gait performance, balance, and fall risk. These outcomes will be measured at baseline and after the intervention period.\n\nThis study will provide evidence on whether combining early time-restricted eating with structured exercise can improve musculoskeletal health and functional ability, and reduce fall risk in older adults.",[29,30,31,32,33],"Nutrition","Health and Wellbeing","Aging","Time Restricted Eating","Bone Health",[32,35,36,37,38],"Exercise Program","Bone Mineral Density","Gait","Balance","NOT_YET_RECRUITING","2026-07-09",{"date":42,"type":43},"2026-07-13","ACTUAL",{"date":45,"type":23},"2026-06-15",{"date":47,"type":23},"2026-12-30",{"name":49,"class":50},"University of Manouba","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":19,"enrollmentInfo":61,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":86},"100644813","dietary-macronutrients-and-gut-microbiota-inflammation-and-metabolic-markers-100644813","NCT07672691","Dietary Macronutrients and Gut Microbiota, Inflammation, and Metabolic Markers","Effects of Diets Differing in Macronutrient Composition on Gut Microbiota Composition, Intestinal Inflammation Markers, Gene Expression Profiles, and Blood Biochemical Parameters in Diverse Populations.","DIETMICRO","Inclusion Criteria:\n\nIn addition to the physical activity requirements described above, the study will include men and women aged 18-60 years with:\n\nBMI not exceeding 40kg\u002Fm²\n\nHabitual mixed diet prior to study enrollment\n\nNormal blood pressure\n\n* Exclusion Criteria:\n\nPoprawiłem już \\*\\*Exclusion Criteria\\*\\* w poprzedniej odpowiedzi - wszystkie te kryteria już tam są wpisane. Oto pełna, ostateczna wersja z wszystkimi wskazanymi kryteriami wyłączenia:\n\n\\*\\*\\* \\*\\*Exclusion Criteria:\\*\\*\n\n* Use of medications regulating \\*\\*glucose levels\\*\\* (e.g., metformin) or \\*\\*blood lipids\\*\\* (e.g., \\*\\*statins\\*\\*)\n* \\*\\*Hypertension\\*\\* or pharmacological treatment for hypertension\n* Diagnosed \\*\\*gastrointestinal disorders\\*\\*, including:\n* Gastric and duodenal ulcers\n* \\*\\*Irritable bowel syndrome (IBS)\\*\\*\n* \\*\\*Ulcerative colitis\\*\\*\n* \\*\\*Celiac disease\\*\\*\n* Chronic use of medications such as:\n* \\*\\*Mesalazine\\*\\*\n* \\*\\*Corticosteroids\\*\\*\n* \\*\\*Statins\\*\\*\n* \\*\\*Proton pump inhibitors (PPI)\\*\\*\n* \\*\\*Non-steroidal anti-inflammatory drugs (NSAIDs)\\*\\*\n* \\*\\*Anticonceptional medications\\*\\*\n* \\*\\*Any supplements\\*\\*\n* \\*\\*Alcohol consumption\\*\\* \\> 2 times\u002Fweek with \\> 15 g alcohol per occasion (approximately 15 g alcohol = 330 mL beer, 150 mL dry red wine, or 50 mL vodka)\n* \\*\\*Smoking cigarettes\\*\\*\n* Following a \\*\\*ketogenic diet\\*\\* or \\*\\*vegetarian diet\\*\\* within \\*\\*1 month\\*\\* prior to study enrollment","18 Years",{"count":62,"type":23},200,[26],"Poniżej znajduje się bardziej płynna i mniej powtarzalna wersja tekstu:\n\nThis 12-week randomized controlled trial will investigate the effects of dietary patterns with different macronutrient compositions on gut microbiota, intestinal inflammation, gene expression, and metabolic health in healthy adults.\n\nParticipants will be randomly assigned to one of three dietary interventions: a ketogenic diet (KD), a vegetarian diet (VD), or a control diet (CD) reflecting their habitual mixed dietary pattern. Adherence to the assigned diet will be monitored through dietary records and regular nutritional counseling.\n\nThe study will evaluate changes in gut microbiota composition, inflammatory biomarkers, transcriptomic profiles, and blood biochemical parameters associated with lipid and glucose metabolism. Blood and stool samples will be collected at predefined time points throughout the intervention, while participants in the KD group will additionally undergo ketone monitoring to assess dietary compliance.\n\nBy comparing the ketogenic and vegetarian diets with a standard mixed diet, this study aims to determine their effects on gut health, metabolic function, and systemic inflammation, thereby providing evidence to inform dietary recommendations.\n\nTa wersja eliminuje powtórzenia (\"diet\", \"study\", \"monitor\", \"effects\"), jest bardziej naturalna stylistycznie i odpowiada standardowi językowemu publikacji w czasopismach z zakresu żywienia i medycyny.",[29,66,67,68],"Ketogenic Diet","Gene Expression","Diet",[70,71,72,73,74,75],"ketogenic diet","gene expression","transcriptomics","biochemical parameters","stool microbiome","ketone bodies","RECRUITING","2026-07-01",{"date":79,"type":43},"2026-07-02",{"date":81,"type":43},"2024-09-02",{"date":83,"type":23},"2028-12-30",{"name":85,"class":50},"The Jerzy Kukuczka Academy of Physical Education in Katowice",2,{"id":88,"slug":89,"hasResults":12,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":94,"targetDuration":4,"studyType":24,"phases":96,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":51},"100633430","comparing-the-effects-of-front-of-package-labeling-schemes-in-indonesia-100633430","NCT07526584","Comparing the Effects of Front-of-Package Labeling Schemes in Indonesia","Comparing the Effects of Two Front-of-Package Labeling Schemes Among Indonesian Consumers","Inclusion Criteria:\n\n* 18 years of age or older\n* Lives in Indonesia\n* Able to read and write in Indonesian\n* Has purchased processed foods in the last month\n\nExclusion Criteria:\n\n* Less than 18 years old\n* Does not live in Indonesia\n* Not able to read and write in Indonesian\n* Has not purchased processed foods in the last month",{"count":95,"type":23},1000,[26],"The goal of this study is to examine what type of front-of-package label (FOPL) would be most effective at discouraging consumption of products high in nutrients of concern in Indonesia. The main questions this experiment aims to answer are:\n\n1. Would nutrient warning labels be more effective at discouraging consumption of products high in nutrients of concern compared to the Nutri-Level label?\n2. Would nutrient warning labels improve consumers' ability to identify unhealthy products compared to the Nutri-Level label?\n\nAdditionally, this experiment also aims to determine how should nutrient warning labels be designed to most effectively discourage consumption of products high in nutrients of concern among Indonesian consumers.",[29,99],"Obesity & Overweight","2026-06-25",{"date":102,"type":43},"2026-06-29",{"date":104,"type":23},"2026-07",{"date":106,"type":23},"2026-08",{"name":108,"class":50},"University of North Carolina, Chapel Hill",{"id":110,"slug":111,"hasResults":12,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":24,"phases":119,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":129,"leadSponsor":131,"locationsCount":51},"100638509","taxation-online-experimental-supermarket-100638509","NCT07593937","Taxation Online Experimental Supermarket","Impact of Taxation and Subsidies on the Nutrition Quality of Purchases in an Online Experimental Supermarket, Overall and by Income Level: a Randomized Control Trial","SUPERNET 2","Inclusion criteria:\n\n* Adult subjects (\\>18 years old) included in the NutriNet-Santé cohort study from all income levels.\n* For the subsidies + taxation arm: inclusion only of low income-participants (below the poverty threshold 1,288€ - 60% of the median standard of living of the population)\n\nExclusion Criteria:\n\n⁃ Subjects never engaging in grocery shopping. Participants will be excluded for this based on self-reported grocery shopping frequency using a short questionnaire at the inception of the study.",{"count":118,"type":23},2239,[26],"Scientific context The increase in the consumption of unhealthy food coupled with a suboptimal consumption of healthier options have increased the risk of non-communicable diseases (NCD) worldwide. Among other public policies to address the rise in NCD -such as front of pack labelling, regulation of food and beverages in schools, marketing regulations targeted to children- taxation has been recognized as a cost-effective strategy to reduce consumption of taxed products. Although subsidies have been used to reduce food insecurity, with the rise in NCD associated with unhealthy diets, studies have explored the feasibility of combining subsidies to incentivize the consumption healthy food with taxes on unhealthy options. The impact of prices on dietary behaviour of consumers has been demonstrated in experimental designs as well as in economic analysis of observational data on purchases. Although some experimental studies have been used to study the impact of taxation and subsidies among specific populations in France, none has evaluated the impact in the general population.\n\nObjective The aim of the study is to evaluate the impact of implementing taxes on unhealthy food and beverages and subsidies to healthy food, separately and combined, on the nutritional quality of purchases, overall and by income level, in an experimental online supermarket.\n\nIntervention description: The intervention includes taxation of lower nutritional quality products (identified using the front-of-pack nutrition label Nutri-Score - classes D and E) and\u002For subsidies for products of higher nutritional quality (identified as raw products or Nutri-Score A and B).\n\nDesign The intervention will be a parallel arm randomized trial stratified by income against a control situation with no changes in prices and the presence of the Nutri-Score on-pack for all pre-packed products in all interventions (control, taxes and subsidies).\n\nExpected public health impact: This study will allow to investigate the potential synergistic effect on the nutritional quality of food choices of combining taxation and income-based subsidies in a context of social inequalities in rising non-communicable disease associated with poor diets. Following a proportional universalism perspective, income-based subsidies can mitigate the regressivity of taxation according to income. As no countries have implemented this combination of fiscal policies to improve diets, the results of this study will contribute to the scientific knowledge on the topic and will provide preliminary results to decision makers.",[29,122],"Food Purchasing Intention",[124,125],"Food taxation","Food subsidies",{"date":127,"type":43},"2026-06-30",{"date":45,"type":43},{"date":130,"type":23},"2026-09-01",{"name":132,"class":50},"University of Paris 13",{"id":134,"slug":135,"hasResults":12,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":141,"targetDuration":4,"studyType":24,"phases":143,"briefSummary":145,"conditions":146,"keywords":150,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":154,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":161},"100562590","phase-3-canadian-critical-care-comparative-effectiveness-platform-100562590","NCT06605144","Canadian Critical Care Comparative Effectiveness Platform","Canadian Critical Care Comparative Effectiveness Platform(e) d'Évaluation Clinique Comparée en Soins Critiques (CEPEC)","CEPEC","VASOPRESSOR DOMAIN There is no minimum age limit in the Vasopressor Domain.\n\nInclusion criteria:\n\n1. Ongoing vasopressor infusion to treat hypotension, or would be used to treat clinician-defined hypotension as part of usual care;\n2. MAP \\\u003C75 mmHg at any point;\n3. Patient expected to be in the ICU for \\>24 hours.\n\nExclusion criteria:\n\n1. Treating team does not have equipoise for at least two contiguous MAP target ranges in the CEPEC Vasopressor Domain;\n2. Acute traumatic brain injury (within 7 days or ongoing active treatment for elevated intracranial pressure);\n3. Acute subarachnoid hemorrhage (within 21 days);\n4. Acute spinal cord injury (within 7 days of injury or ongoing vasopressor therapy for suspected spinal cord ischemia);\n5. Lung, heart, liver, kidney transplant recipient (within 7 days);\n6. Patient expected to become an organ donor (Donor Neurologic Death - DND or Donation After Circulatory Death - DCD);\n7. More than 24 hours since meeting inclusion criteria in the ICU;\n8. Previously randomized into the CEPEC Vasopressor Domain or a confounding trial.\n\nPLATELET DOMAIN\n\nInclusion criteria:\n\n1. Adult patients (age ≥18 years) admitted to the ICU;\n2. Latest platelet count in this hospital admission \\\u003C50×109\u002FL;\n3. Planned to undergo a specified low-moderate bleeding risk invasive procedure.\n\nExclusion criteria:\n\n1. Ongoing major hemorrhage requiring blood products and\u002For surgical\u002F radiological intervention;\n2. Intracranial hemorrhage within prior 72 hours;\n3. Contraindications to platelet transfusion (e.g. thrombotic microangiopathies, heparin-induced thrombocytopenia, recent history of immune thrombocytopaenia, congenital platelet function defects);\n4. Known advance decision of refusing blood\u002Fblood component transfusions;\n5. Acute promyelocytic leukemia (APML);\n6. Death perceived as imminent or admission for palliation;\n7. Previously randomized into the CEPEC Platelet Domain or the T4P Trial;\n8. Fulfilled all the inclusion criteria and none of the exclusion criteria ≥72 hours.\n\nNUTRITION DOMAIN\n\nInclusion criteria:\n\n1. Critically ill patients ≥18 years of age;\n2. Are invasively mechanically ventilated (including endotracheal tube or tracheostomy);\n3. Orogastric\u002Fnasogastric tube in place; or have an in dwelling percutaneous gastric tube (with confirmed placement);\n4. Treating team has started or has the intention of providing enteral nutrition.\n\nExclusion criteria:\n\n1. Patients who have had gastrointestinal (GI) surgery; in the last 3 months and deemed not ready to receive possible bolus nutrition;\n2. Bowel obstruction or ischemia; active;\n3. Has a post-pyloric small bowel feeding tube;\n4. Active GI bleeding;\n5. Patient who is chronically receiving enteral nutrition.",{"count":142,"type":23},5500,[144],"PHASE3","The Canadian Critical Care Comparative Effectiveness Platform(e) d'Évaluation Clinique Comparée en soins Critiques (CEPEC) is an international multi-centered randomized adaptive platform clinical trial. CEPEC will evaluate supportive care interventions that are used routinely in intensive care units throughout the world.",[147,148,149,29],"Intensive Care Unit ICU","Vasopressor","Platelet",[151,152,148,149,153],"ICU","Adaptive platform trial","Enteral nutrition",{"date":127,"type":43},{"date":156,"type":43},"2025-03-23",{"date":158,"type":23},"2030-06-30",{"name":160,"class":50},"Université de Sherbrooke",9,{"id":163,"slug":164,"hasResults":12,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":24,"phases":171,"briefSummary":172,"conditions":173,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":185},"100493169","nutrition-for-precision-health-powered-by-the-all-of-us-100493169","NCT05701657","Nutrition for Precision Health, Powered by the All of Us","Nutrition for Precision Health, Powered by the All of Us Research Program","Inclusion Criteria:\n\n* Overall Inclusion -- Participants 18 years of age or older who have completed the primary All of Us consent process, Electronic Health Record consent process, have provided at least one All of Us biospecimen suitable for DNA sequencing, and have completed All of Us Participant Provided Information (PPI) Modules 1-3 (Basics, Overall Health, and Lifestyle); Speak English or Spanish; Able and willing to comply with study requirements and consent to participate.\n* Module 1 -- Must be willing and able to comply with Module 1 protocol; Must provide informed consent for Module 1.\n* Module 2 -- Must have completed Module 1; Must provide informed consent for Module 2; Must agree to comply with protocol over a period of approximately 10 to 12 weeks and up to six months. This includes consuming only the foods provided during periods of controlled feeding. Module 2 has three controlled feeding periods each lasting approximately two weeks with at least two weeks between feeding periods, and up to 6 months allowed for completion of the Module.\n* Module 3 -- Must have completed Module 1; Must provide informed consent for Module 3; Must agree to comply with protocol over a period of approximately 10 to 12 weeks and up to 6 months. This includes being domiciled three times, for two weeks each, and consuming only the foods provided during the domiciled periods. There is at least two weeks between domiciled periods, and up to 6 months allowed for completion of the Module.\n\nExclusion Criteria:\n\n* Module 1\n\n  1. Any change to the participant's status from the time of All of Us enrollment that would render them ineligible for All of Us (e.g., being incarcerated, no longer living in the United States, or withdrawn from that study).\n  2. Inability to provide informed consent and engage in informed consent procedures\n  3. Participants who suffer from allergic reactions to, or are unwilling to consume, any components of the liquid mixed meal (e.g., milk products, soy products)\n  4. Barriers to safe insertion of peripheral IV canula:\n\n     1. Contraindications to peripheral IV canula insertion such as local skin infection, inflammation, trauma or burns if all the upper extremities were involved and there is no unaffected extremity available for IV placement; or\n     2. A need for long-term IV access (e.g., ESRD); or\n     3. Lymphedema or deep vein thrombosis (DVT) in the extremity of the IV (in the case where another extremity is not available); or\n     4. Coagulopathy requiring blood thinning products; or\n     5. Arteriovenous (AV) graft or fistula in the extremity of the IV (in the case where another extremity is not available)\n  5. Pregnancy-related conditions:\n\n     1. Gestational age precluding completion of the Module by 36 weeks. A pregnant participant should complete visit 1 by gestational age 34 weeks, 0 days and complete Module 1 by week 36.\n     2. Severe morning sickness limiting mixed meal tolerance test (MMTT) consumption\n  6. Certain types of disease states:\n\n     1. Dumping syndrome or inability to consume the volume of the MMTT liquid\n     2. Severe malabsorption such as history of short gut syndrome or need for parenteral or enteral nutrition\n     3. Less than 12-months post-metabolic or bariatric surgery\n     4. History of chronic pancreatitis (e.g., Cystic fibrosis) complicated by inability to tolerate the volume of the MMTT liquid\n     5. Health conditions requiring chronic blood transfusions or iron infusions\n     6. Hemoglobin \\\u003C9.5 g\u002FdL at screening\n  7. Serious illness and in hospice or palliative care for terminal disease\n  8. Swallowing issues:\n\n     1. Self-reported difficulty tolerating solids or liquids\n     2. Aspiration risks that require change in thickness of liquid or dietary modifications\n  9. Short term antibiotic use. For example, active antibiotics use for an ongoing acute infection\n  10. Blood donation in the last 3 months\n  11. GLP-1 agonist medication (e.g. Semaglutide) instability as defined by less than 3 months of continuous use\n  12. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's and\u002For team's opinion jeopardizes the safety of the participant or others or would interfere with adherence to the protocol.\n* Module 2\n\n  1. Any change to the participant's status from the time of All of Us enrollment that would render them ineligible for All of Us (e.g., being incarcerated, no longer living in the United States, or withdrawn from that study)\n  2. All the above mentioned exclusion criteria for Module 1 (except inability to consume components of the liquid mixed meal)\n  3. Inability to provide informed consent and engage in informed consent procedures\n  4. Inability or failure to complete all critical elements from Module 1 (dietary, physical activity and sleep assessments, continuous glucose monitoring, MMTT)\n  5. Participants who are already enrolled in Module 3\n  6. Participants who are unlikely to be able to adhere to the protocol, based on structured adherence assessment by a study registered dietitian or other trained staff. This includes participants who have known allergic reactions to, or unwillingness to consume, study foods in Module 2 (e.g., gluten, meat, fish, nuts, dairy products) that cannot be reasonably accommodated by the metabolic kitchen within allowable criteria for the test diets.\n  7. Participants who plan to relocate to an area not served by NPH or travel plans that do not permit completion of the Module over a period of up to 6 months.\n  8. Pregnancy-related conditions:\n\n     1. Gestational age precluding completion of the Module by week 36. A pregnant participant must be able to begin the first diet by gestational age 26 weeks, 0 days and complete the Module by week 36.\n     2. High risk pregnancy defined as fetal anomaly, gestational hypertension (SBP \\>140 mmHg and DBP \\>90 mmHg), pre-eclampsia, or gestational diabetes mellitus\n  9. Possible ethanol (alcohol) use disorder defined by Alcohol Use Disorders Identification Test (AUDIT) score of \\>15\n  10. History of surgery for the treatment of obesity and:\n\n      1. Self-reported dumping syndrome; or\n      2. Following a special diet prescribed by their practitioner\n  11. Uncontrolled disease states:\n\n      1. Hypertension \\>160\u002F100mmHg\n      2. Exacerbation of underlying gastrointestinal disease, including inflammatory bowel disease or other malabsorptive disorders\n      3. Decompensated cirrhosis\n      4. Previously diagnosed diabetes Mellitus with HbA1c \\>12% at screening\n      5. Newly diagnosed diabetes within the past three months, or HbA1c \\>6.5% at screening in a person not previously diagnosed with diabetes.\n  12. Participants with a history of end-stage renal disease (ESRD) on hemodialysis\n  13. Active infectious diseases (e.g., active tuberculosis \\\u003C 3 months from symptom onset or positive test, COVID \\\u003C 1 month from symptom onset or positive test)\n  14. Malignancy (e.g., cancer) actively receiving cytotoxic chemotherapy (oral or infusions) treatment except for nonmelanoma skin cancers during the study period\n  15. Participants who require dietary restrictions due to a medical condition or are on a prescribed diet for underlying chronic diseases\n  16. Participants with type 1 or type 2 diabetes on insulin\n  17. Participants aged ≥ 75 years with type 2 diabetes taking prescribed medications that can cause hypoglycemia (e.g. sulfonylureas, glinides), or on a prescribed diet\n  18. Hospitalization for a chronic disease (e.g., congestive heart failure, stroke) within the past three months\n  19. Requiring transfusions\u002Fapheresis during study period\n  20. Participants with a current diagnosis of, or who have received treatment for, bulimia or anorexia nervosa within the past 3 years\n  21. Participants with major psychiatric disorders, including major depression, schizophrenia, or psychosis, who have been hospitalized in the past six (6) months or are currently enrolled in treatment programs\n  22. Hemoglobin \\\u003C9.5 g\u002FdL at screening\n  23. Myocardial infarction, invasive cardiac procedure, participation in a cardiac or acute rehabilitation programs, transient ischemic attacks, or unstable arrhythmias within the past 3 months\n  24. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's opinion, might jeopardize the safety of the participant or others, or be expected to interfere with adherence to the protocol.\n* Module 3\n\n  1. All the above mentioned exclusion criteria for Modules 1 and 2\n  2. Participants who are already enrolled in Module 2\n  3. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's opinion, might jeopardize the safety of the participant or others, or would interfere with adherence to the protocol\n  4. Inability to abstain from tobacco or nicotine use, vaping, alcohol, illicit drug use, or recreational drug use for two (2) consecutive weeks while domiciled in the clinical unit. Nicotine gum, pouch, or patch are permitted.\n  5. Any condition requiring in-person treatments or visits during the study period. This will not be accommodated by the domiciling protocol; however, tele-health visits with the participants regular doctor are permitted.\n  6. Lactation or other infant care needs that cannot be accommodated while domiciled in the clinical unit\n  7. Depression as assessed by:\n\n     1. Patient Health Questionnaire (PHQ-9) score ≥ 15; or\n     2. Affirmative answer to PHQ-9 suicidality question: \"Thoughts that you would be better off dead or of hurting yourself in some way\"\n  8. Unable to engage in daily self-care activities (e.g., bathing, transferring, toileting, feeding, dressing)\n  9. Uncontrolled endocrine disorders (such as Cushing's disease, pituitary disorders, diabetes)\n  10. Uncontrolled pain requiring frequent or daily treatment, or adjustment of medication requiring weekly or bi-weekly visits. Pain medications used on an as-needed basis (PRN), such as acetaminophen or NSAIDs, are not excluded.\n  11. Chronic prescription medications that would pose logistical and safety issues for participation",{"count":170,"type":23},8000,[26],"The goal of this Nutrition for Precision Health (NPH) powered by All of Us research study is to develop Artificial Intelligence\u002FMachine Learning (AI\u002FML) algorithms that predict individual responses to diet patterns using rich multimodal data streams collected across multiple domains (e.g., behavior, social, environmental, clinical and molecular biomarkers). NPH includes a large phenotyping cohort (Module 1, N=8000) and two separate follow-up groups drawn from a subset of Module 1participants. One group (Module 2, N=1200) receives three distinct diets in a 14-day crossover sequence, with at least a 14-day washout period between diets, while living in their own homes. A second group (Module 3, N=150) receives the same three diets under full-time supervision in a residential research setting. We will train and test AI\u002FML models to predict 0-4 hour postprandial response curves for glucose, insulin, triglycerides, and GLP-1, to the standardized diet-specific meal test (DSMT) collected after each of the three different diets delivered in Module 2. Each diet functions as a controlled stimulus to reveal biological features (such as individual variables, patterns, or clusters of measurements) that best predict a person's response.\n\nThe Module 2 DSMT response curves are the primary outcomes (dependent variables) for AI\u002FML algorithms that predict individual responses to diet patterns.\n\nAs a secondary objective, NPH will evaluate the validity and acceptability of technology-based dietary assessment tools. The Automated Self-Administered 24-hour recall (ASA24), Automatic Ingestion Monitor-2 (AIM-2), and the mobile food record (mFR) will be evaluated in Modules 2 and 3, and the ASA24 food record and the image-assisted ASA24 recall will be evaluated only in Module 3. Total energy intake, macronutrient and dietary fiber intake data are the main outcomes for validity testing compared against measures of actual intake. Acceptability will be determined from feedback surveys.",[29,174,175],"Health","Dietary Habits","2026-06-01",{"date":178,"type":43},"2026-06-03",{"date":180,"type":43},"2023-04-14",{"date":182,"type":23},"2027-01-31",{"name":184,"class":50},"RTI International",14,{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":17,"sex":18,"minAge":193,"maxAge":194,"enrollmentInfo":195,"targetDuration":197,"studyType":198,"phases":4,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":213,"leadSponsor":215,"locationsCount":86},"100636659","maternal-methyl-nutrient-status-and-infant-neurodevelopment-study-100636659","NCT07568561","Maternal Methyl-Nutrient Status and Infant Neurodevelopment Study","Maternal Methyl-Nutrient Status During Pregnancy and Its Association With Infant Neurodevelopment: Exploring Potential Mechanisms","Inclusion Criteria for Pregnant Women\n\n* Aged 20-45 years\n* Singleton pregnancy\n* Receiving routine prenatal care at the study site and planning to deliver at Far Eastern Memorial Hospital\n\nExclusion Criteria for Pregnant Women\n\n* Diagnosed with major chronic diseases, including renal disease (defined as chronic kidney disease stage 3 or above or history of renal transplantation), liver disease (defined as liver cirrhosis or history of liver transplantation), or malignancy\n* Alcohol consumption during pregnancy\n* Diagnosed with eating disorders or psychiatric conditions that may impair the assessment of nutritional status\n\nInclusion Criteria for Newborns\n\n● Newborns delivered by mothers who participate in this study\n\nExclusion Criteria for Newborns\n\n* Diagnosed with congenital anomalies, epilepsy, or severe brain injury\n* Inability to complete neurodevelopmental assessments at 6 months, 1 year, and 2 years of age at the study site\n* Infants whose mothers are diagnosed with eating disorders or psychiatric conditions that may impair the assessment of nutritional status","0 Days","45 Years",{"count":196,"type":23},240,"2 Years","OBSERVATIONAL","This prospective cohort study examines the relationship between maternal methyl-nutrient status during pregnancy and offspring neurodevelopment. It integrates maternal dietary, biomarker, genetic, and microbiome data and follows children up to 24 months.",[201,29,202,203,204,205,206,207,208],"Infant Neurodevelopment","Methylation","Birth Outcomes","Pregnancy","Dietary Quality","Dietary Intake Assessment","Homocysteine","Trimethylamine N-oxide (TMAO)","2026-05-27",{"date":211,"type":43},"2026-05-29",{"date":209,"type":43},{"date":214,"type":23},"2029-01-18",{"name":216,"class":50},"Far Eastern Memorial Hospital",{"id":218,"slug":219,"hasResults":12,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":223,"eligibilityCriteria":224,"healthyVolunteers":17,"sex":18,"minAge":225,"maxAge":226,"enrollmentInfo":227,"targetDuration":4,"studyType":24,"phases":228,"briefSummary":229,"conditions":230,"keywords":234,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":51},"100638562","eating-almonds-before-a-meal-to-control-blood-sugar-100638562","NCT07603739","Eating Almonds Before a Meal to Control Blood Sugar","Interindividual Variability in the Effect of Premeal Almond Supplementation on Glycemic Control - a Double Crossover Study","NUTS","Inclusion Criteria:\n\n* Adults aged 25-50 years\n* Females over 40 years must have had a cycle in the last 6 months\n* Body mass index (BMI) at least 18.5 and at most 55.0 kg\u002Fm2\n* Impaired blood glucose by at least one of the following criteria:\n* Fasting blood glucose at least 100 mg\u002FdL (5.6 mmol\u002FL) and less than 125 mg\u002FdL (6.9 mmol\u002FL)\n* HbA1c at least 5.7% and less than 6.5%\n* Willing and able to comply with study foods\n* Willing and able to ingest acetaminophen as part of study procedures\n* Able to read, speak, and understand English\n\nExclusion Criteria:\n\n* Weight change ≥5% in past 6 months, actively trying to lose weight, or unwilling to remain weight stable throughout the study based on self-report\n* Recent history within past 12 months of medical provider-diagnosed cardiovascular, renal, or liver disease that required treatment\n* Current or past diagnosis of cancer (except skin cancer) in the last 5 years\n* Current or past diagnosis of type 1 or type 2 diabetes\n* Recent history within past 12 months of medical provider-diagnosed gastrointestinal or neurological disorders if not managed\u002Fstable for at least 3 months (with or without treatment)\n* Recent history within past 12 months of medical provider-diagnosed psychiatric disorders including eating disorders or severe depression if not managed\u002Fstable for at least 3 months (with or without treatment)\n* Food allergies or other reasons preventing consumption of study foods\n* Any glucose-lowering medication except biguanides (e.g., Metformin) if stable for at least 3 months or incretins (i.e., GLP-1RA-based) if stable for at least 3 months\n* Current smoking or vaping or history of smoking or vaping in the past 6 months\n* Binge and\u002For heavy drinking (i.e., \\>3 drinks on any given occasion and\u002For \\>7 drinks\u002Fweek)\n* Currently pregnant or planning to become pregnant or breastfeed in the next 3 months by self-report","25 Years","50 Years",{"count":7,"type":23},[26],"The goal of this study is to learn whether eating a small serving of almonds before meals can improve blood sugar control in adults who have early signs of problems with blood sugar regulation. The main questions it aims to answer are:\n\n1. Does eating almonds before a meal reduce the rise in blood sugar after eating?\n2. Do some people consistently benefit more than others from eating almonds before meals?",[231,232,233,29],"Glucose Control","Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)","Precision Medicine",[29,233,235,231,236,237,238],"Precision Nutrition","Impaired Glucose Tolerance","Insulin Resistance","Prediabetes","2026-05-16",{"date":241,"type":43},"2026-05-22",{"date":243,"type":23},"2026-06",{"date":245,"type":23},"2028-07",{"name":247,"class":50},"Pennington Biomedical Research Center",{"id":249,"slug":250,"hasResults":12,"nctId":251,"briefTitle":252,"officialTitle":252,"acronym":4,"eligibilityCriteria":253,"healthyVolunteers":12,"sex":18,"minAge":254,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":24,"phases":257,"briefSummary":258,"conditions":259,"keywords":262,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":275},"100634523","evaluation-of-7-day-vs-1-day-packaging-of-small-quantity-lipid-based-nutrition-supplementation-sq-lns-100634523","NCT07540793","Evaluation of 7-day vs 1-day Packaging of Small Quantity Lipid-based Nutrition Supplementation (SQ-LNS)","Inclusion Criteria (must meet all):\n\n* Written informed consent from head of household\n* Household within the study area\n* Available for the full 8-week study period\n* 1 child aged 6-22 months in the household at time of enrollment\n* Child has MUAC ≥ 12.5cm\n* Child does not have any clinical complications requiring inpatient treatment or referral to the health post, according to Ethiopian malnutrition treatment guidelines\\*\\*\n* Child is not allergic to peanuts, milk, or soy\n* Household does not have multiple children within the eligible age range\n\nExclusion Criteria (any excludes):\n\n* Head of household declines to sign written informed consent\n* Household is outside of the study area\n* Not available for the full 8-week study period\n* House has either multiple children aged 6-22 months in the household at time of enrollment, or 0 children aged 6-22 months at time of enrollment\n* Child has MUAC \\\u003C 12.5cm\n* Child has any clinical complications requiring inpatient treatment or referral to the health post, according to Ethiopian malnutrition treatment guidelines\n* Child is allergic to peanuts, milk, or soy","6 Months",{"count":256,"type":23},100,[26],"Small Quantity Lipid-based Nutrient Supplements (SQ-LNS), are fortified, lipid-based nutritional supplements that were specifically designed for children 6-24 months to prevent malnutrition. Recent research has shown reductions in mortality, severe wasting, severe stunting, iron deficiency anemia, and developmental delays.\n\nSQ-LNS is currently available in individual daily dose packets of 20g. Healthy children age 6-24 months receive 1 packet per day (1dp), and are typically given a 1- or 2- month supply at a time (30-60 packets).\n\nRecently, Nutriset Développement has developed a new packaging design for SQ-LNS that reduces the cost by over 15% overall, through production efficiency with 40% less packaging, and improved transportation efficiency by 20%. This new packaging is a 140g packet that will allow 20g to be dispensed daily for 7 days (7dp). The packaging has a chamber that will allow for accurate 10g dosing (either twice daily, or twice at once). Users of the packaging will also be able to close the spout to minimize risk of microbiological contamination.\n\nEdesia Nutrition is working with Nutriset to conduct field testing of this new packaging for SQ-LNS, and this mixed-methods study in North Shoa Zone, Amhara Region, Ethiopia, will help inform recommendations for the future use of the package. The study seeks to determine (1) the acceptability of integrating SQ-LNS distribution into the malnutrition program; (2) whether adherence to the 2 different package types differs, and if there are differences in usage; (3) and how the packages perform over time, their perceived safety and functionality, and how they are stored.\n\nEducational and communication tools will be developed and pre-tested as part of this study, and will become part of the final deliverable package to Edesia Nutrition, in addition to final recommendations on the product packaging, findings about how the packages are used, and behavior change and nutrition education strategies.\n\nThe primary outcome of the quantitative evaluation will be adherence, calculated as the number of delivered doses of SQ-LNS divided by the number of expected doses per week (7).\n\nAdherence will be measured via weekly self-report via caregiver interview and counts of return of used and unused packages during weekly home visits. The percentage of children who receive a dose during structured observation periods will be calculated. Each adherence outcome will be analyzed separately.",[260,261,29],"Prevention","Malnutrition, Child",[263,264,265],"Small Quantity Lipid-based Nutrient Supplement","Child nutrition","Malnutrition prevention","2026-05-11",{"date":268,"type":43},"2026-05-14",{"date":270,"type":23},"2026-05",{"date":272,"type":23},"2026-12",{"name":274,"class":50},"University of California, San Francisco",3,{"id":277,"slug":278,"hasResults":12,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":282,"eligibilityCriteria":283,"healthyVolunteers":17,"sex":18,"minAge":284,"maxAge":285,"enrollmentInfo":286,"targetDuration":4,"studyType":24,"phases":288,"briefSummary":289,"conditions":290,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":51},"100637470","effects-of-plant-foods-on-gastrointestinal-and-cardiometabolic-health-100637470","NCT07586111","Effects of Plant Foods on Gastrointestinal and Cardiometabolic Health","A Randomised Controlled Trial Investigating the Impact of Plant Foods on Gastrointestinal and Cardiometabolic Health","PLANTIFUL","Inclusion Criteria:\n\n* Adults aged 30-70 years of age\n* Capacity to give informed consent in English\n* Consume equal or less than the average UK plant food intake (number and quantity)\n* Consume less than 30 g\u002Fd of fibre\n* BMI 18.50-29.99 kg\u002Fm2\n* Willing to complete the trial by adhering to the diet intervention, complete questionnaires, provide stool, urine and blood samples, record weight and other anthropometric values and record food intake throughout the study\n* Willing and able to adhere to the protocol for the diet intervention for the whole duration of the trial (e.g., appropriate space in freezer to store meals, access to oven\u002Fmicrowave, no planned travelling)\n* Willing to discontinue use of prebiotics and probiotics 4 weeks prior and during the intervention period\n* Willing to consume animal products daily\n* Medication use is stable in women receiving hormone replacement therapy (stable use for the past 3 months)\n\nExclusion Criteria:\n\n* Medical history of any of the following: diabetes, major active or historic psychiatric conditions (e.g., schizophrenia), current eating disorder, alcohol abuse, active treatment for cancer in the last year, severe neurological, endocrine, renal, cardiac or pulmonary disease (or any other chronic medical condition), severe oesophagitis, gastritis or duodenitis, active diverticulitis or intestinal\u002Fcolonic strictures, Coeliac disease, Crohn's disease or Ulcerative colitis, stem cell or organ transplant, gut resection surgery (excluding appendicectomy and cholecystectomy), bleeding disorder, anaphylaxis or any other major or chronic condition known to impact study outcome measures.\n* A current diagnosis of IBS, as defined by the Rome IV criteria.\n* Taking medications known to affect outcomes of interest, including:\n* Prebiotics and probiotics 4 weeks prior to enrolment.\n* Antibiotics within 4 weeks of enrolment.\n* Medications known to affect blood pressure, appetite, gut motility, glucose control, or lipid levels within 4 weeks of enrolment.\n* Taking any dietary supplements, apart from vitamin D or calcium supplements, 4 weeks prior to enrolment.\n* Allergy or intolerance to any study food ingredients.\n* Unable\u002Fdislike\u002Funwilling to consume study foods or adhere to study protocol (e.g., not willing to drink a maximum 9 units of alcohol a week or consume animal products).\n* Currently reported pregnant or lactating.\n* Unwilling or unable to consume non-halal or non-kosher products.\n* Estimated energy requirements of \\\u003C1,500 kcal\u002Fday or \\>3,000 kcal\u002Fday.\n* Unexplained or unintentional weight loss in the past six months.","30 Years","70 Years",{"count":287,"type":23},248,[26],"The aim of this randomised controlled trial is to investigate the effects of plant foods on gastrointestinal and cardiometabolic health in healthy adults aged 30-70 years old. The main question it will answer is \"what is the effect of plant foods on alpha-diversity of the gut microbiota?\".\n\nResearchers will compare two diets containing plant foods to see if they have different effects on gastrointestinal and cardiometabolic health.\n\nParticipants will be asked to replace all their meals, snacks and drinks with those provided by the study team for four weeks (6 days\u002Fweek). Participants will also be asked to attend the research facility on three occasions to:\n\n* Provide a blood sample\n* Provide a urine sample\n* Provide a stool sample\n* Have their body composition assessed\n* Have an ultrasound of their artery (arm)\n* Have their blood pressure measured\n* Answer questionnaires related to dietary intake, mental health, physical activity, quality of life, diet acceptability and adherence",[291,29],"Healthy Adult Volunteers","2026-05-07",{"date":268,"type":43},{"date":295,"type":23},"2026-04",{"date":297,"type":23},"2028-11",{"name":299,"class":50},"King's College London",{"id":301,"slug":302,"hasResults":12,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":306,"eligibilityCriteria":307,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":308,"targetDuration":4,"studyType":24,"phases":310,"briefSummary":311,"conditions":312,"keywords":316,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":323,"lastUpdatePostDateStruct":324,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":51},"100608225","randomized-double-blind-crossover-trial-comparing-low-gi-functional-vs-standard-wholegrain-carbohydrates-on-glycolipid-metabolism-and-vascular-stress-markers-in-adults-with-suboptimal-triglyceridemia-100608225","NCT07198789","Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia","Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial to Evaluate the Effect of a Functional Low-Glycemic Index Carbohydrates Versus Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Subjects With Suboptimal Triglyceridemia","GLOW","Inclusion Criteria:\n\n* Male or female aged ≥ 18 years\n* TG\\>150 mg\u002FdL\n* Subjects who have the capability to communicate and to comply with the study's requirements.\n* Subjects agree to participate in the study and having dated and signed the informed consent form.\n\nExclusion Criteria:\n\n* Gluten hypersensitivity\u002FCoeliac disease diagnosis\n* BMI\\>30 kg\u002Fm2\n* Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months\n* Any medical or surgical condition that would limit the patient adhesion to the study protocol.",{"count":309,"type":23},40,[26],"Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.",[313,314,315,29],"Cardiovascular Prevention","Diabetes Prevention","Inflammation",[317,318,319,320,321,322],"Low glycemic index","Low-GI diet","Triglycerides-Glucose Index","Low-glycemic index carbohydrates","Wholegrain carbohydrates","Altograno®","2026-04-27",{"date":325,"type":43},"2026-05-01",{"date":327,"type":43},"2026-02-02",{"date":329,"type":23},"2026-09-29",{"name":331,"class":50},"University of Bologna",{"id":333,"slug":334,"hasResults":12,"nctId":335,"briefTitle":336,"officialTitle":337,"acronym":338,"eligibilityCriteria":339,"healthyVolunteers":17,"sex":18,"minAge":340,"maxAge":341,"enrollmentInfo":342,"targetDuration":4,"studyType":24,"phases":343,"briefSummary":344,"conditions":345,"keywords":350,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":361,"completionDateStruct":363,"leadSponsor":365,"locationsCount":51},"100576989","eplatform-for-promoting-health-in-schools-100576989","NCT06792461","ePlatform for Promoting Health in Schools","A Randomized Controlled Trial to Evaluate the Implementation of an eHealth Platform for Promoting Healthy Habits Among Adolescents From Socially Disadvantaged Settings: the ePro-Schools Project","ePro-Schools","Inclusion Criteria\n\nAdolescents:\n\n* Students enrolled in 1st, 2nd, or 3rd year of ESO (ages approximately 11-16) at participating secondary schools located in the Central Catalonia region, particularly those in socially disadvantaged settings.\n* All genders will be eligible.\n* Written informed consent must be provided by both the adolescent and their parent(s)\u002Flegal guardian(s).\n\nPhysical Education Teachers:\n\n* Physical education teachers currently working at the participating secondary schools.\n* Must be 18 years of age or older.\n* Must provide written informed consent to participate.\n\nExclusion Criteria\n\n* Individuals (adolescents or teachers) who do not provide written informed consent will be excluded.\n* No other exclusion criteria will be applied.","11 Years","16 Years",{"count":95,"type":23},[26],"There are few public health and educational policies specifically aimed at promoting physical activity, healthy dietary habits, and reducing sedentary behaviour among adolescents from socially disadvantaged backgrounds. ePro-Schools will co-design, pilot and evaluate an evidence-based program, delivered via a modular eHealth platform, to promote physical activity and healthy eating, and reduce time in sedentary behaviours. A profound co-creation process involving adolescents, school staff, and policymakers-alongside the adaptation of previous interventions by consortium members-will support the program's development. The ePro-Schools platform will contain modules for adolescents and their parents, teachers and school administration. Although the platform will be implemented through schools, it will include content to be implemented outside the school setting. The intervention program will be evaluated through a randomised controlled trial conducted in six secondary schools in Central Catalonia that aims to include 1000 adolescents. Schools have been randomised (1:1) into an intervention and a waiting-list control group.\n\nThe evaluation of the program includes effectiveness, cost-effectiveness and process evaluation. Physical activity, sedentary behaviour and eating habits are the primary effectiveness outcomes of the trial. Secondary outcomes include fitness, water consumption, quality of life, depressive symptoms, social isolation and sleep quality. Using implementation science methodology, ePro-Schools will co-design transferable evidence-based practices and methodologies and guidance for scaling up the platform with policymakers and stakeholders, as well as informing specialists, policymakers and the general public.",[346,347,348,29,349],"Health Promotion","Health Education","Physical Activity","Behaviour Change",[351,352,353,354,355,356,357],"eHealth","Adolescents","Socially disadvantaged settings","Randomized control trial","Co-design","School-based interventions","Health promotion","2026-04-23",{"date":360,"type":43},"2026-04-29",{"date":362,"type":43},"2025-09-08",{"date":364,"type":23},"2027-03",{"name":366,"class":50},"Fundació Sant Joan de Déu",{"id":368,"slug":369,"hasResults":12,"nctId":370,"briefTitle":371,"officialTitle":372,"acronym":4,"eligibilityCriteria":373,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":374,"targetDuration":4,"studyType":24,"phases":376,"briefSummary":377,"conditions":378,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":380,"lastUpdatePostDateStruct":381,"startDateStruct":383,"completionDateStruct":385,"leadSponsor":387,"locationsCount":51},"100619544","impacts-of-sugar-warnings-on-weight-bias-100619544","NCT07346001","Impacts of Sugar Warnings on Weight Bias","Impacts of Prolonged Exposure to Added Sugar Warning Labels on Explicit Weight Bias: a Randomized Controlled Trial","Inclusion Criteria:\n\n* 18 years and older\n* Bought sugary drinks from a store at least once during the past week\n* Willing to attend 4 in-person study appointments\n\nExclusion Criteria:\n\n• Living in the same household as someone else in the study",{"count":375,"type":23},543,[26],"This study aims to examine the effects of added sugar warning labels for sugar-sweetened beverages (SSBs) on explicit weight bias and body weight attributional judgements. Participants will be assigned to view either control labels or added sugar warning labels applied on SSBs in an experimental store. Participants will shop for beverages in the store and take a computer survey during four visits to the store, spaced approximately one week apart.",[29,379],"Diet Interventions","2026-04-14",{"date":382,"type":43},"2026-04-16",{"date":384,"type":43},"2026-02-16",{"date":386,"type":23},"2027-12",{"name":108,"class":50},{"id":389,"slug":390,"hasResults":12,"nctId":391,"briefTitle":392,"officialTitle":393,"acronym":4,"eligibilityCriteria":394,"healthyVolunteers":17,"sex":18,"minAge":395,"maxAge":396,"enrollmentInfo":397,"targetDuration":4,"studyType":24,"phases":399,"briefSummary":400,"conditions":401,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":402,"lastUpdatePostDateStruct":403,"startDateStruct":405,"completionDateStruct":406,"leadSponsor":407,"locationsCount":4},"100631493","impact-of-protein-formulations-on-the-stimulation-of-muscle-protein-synthesis-100631493","NCT07501403","Impact of Protein Formulations on the Stimulation of Muscle Protein Synthesis","Impact of Protein Formulations on Postprandial Aminoacidemia and the Stimulation of Resting and Post-exercise Muscle Protein Synthesis in Healthy Adults","Inclusion Criteria:\n\n1\\. Age 19-40 years of age, inclusive • 2. Pre-menopausal 3. Recreationally-active 4. No health conditions that would prevent him\u002Fher from fulfilling the study requirements as judged by the Clinical Investigator on the basis of medical history 5. Non-user of tobacco or nicotine products (e.g.\n\ncigarette smoking, vaping, chewing tobacco) within 12 months of Visit 1, with no plans to begin use during the study period 6. BMI 18.5-29.9 kg\u002Fm2 7. Willing to adhere to all study procedures and sign forms providing informed consent to participate in the study and authorization to release relevant protected health information to the Clinical Investigator\n\nExclusion Criteria:\n\n1\\. Female who is pregnant, planning to be pregnant during the study period, lactating, or is of childbearing potential and is unwilling to commit to the use of a medically approved form of contraception throughout the study period 2. Female with irregular menstrual cycles (i.e., \\\u003C21 day or \\>35 day cycle) 3. Participation in previous research using a 13C stable isotope tracer 4. Participation in other ongoing research that interferes with this study (e.g., conflicting diet, activity interventions, etc.) 5. History or presence of clinically important cardiac, renal, hepatic, endocrine, pulmonary, biliary, pancreatic, metabolic, gastrointestinal motility or neurological disorders that may affect the participant's ability to adhere to the study protocol and\u002For affect study outcomes, in the judgment of the Investigator 6. Currently in a habitual exercise training program (≥ 3 days\u002Fweek of structured exercise) or plans to initiate an exercise training program during the study period 7. Self-report of unstable weight (variation \\>5% of bodyweight in last 6 months prior to visit 1) 8. Phenylketonuria 9. Previously hospitalized for COVID-19 without a cardiovascular workup screening for cardiovascular issues post-infection 10. Recovering from COVID-19 infection within the preceding 10 days from visits 1 11. Uncontrolled hypertension (systolic blood pressure ≥140mm Hg or diastolic blood pressure ≥90mm Hg) as defined by the blood pressure measured at visit 1.\n\nStable use of hypertension medication is allowed (defined as no change in medication regimen ≤ 90 days of visit 1) 12. Any signs or symptoms of active infection of clinical relevance (e.g. urinary tract or respiratory) within 5 days prior to any test visit. If an infection occurs during the study period, test visits should be rescheduled until all signs and symptoms have resolved and any treatment has been completed at least 5 days prior to testing 13. History or presence of cancer in the prior 2 years, except for non-melanoma skin cancer 14. History of any major trauma or major surgical event within 2 months of visit 1 15. Self-report history of extreme dietary behavior (e.g., vegetarian diet, keto diet, anorexia nervosa, bulimia nervosa, binge eating) 16. Taking medications affecting gastrointestinal motility 17. Liver medication use 18. Recent use of antihyperglycemic (e.g. metformin, insulin, DPP 4 inhibitors, SGLT-2 inhibitors, GIP agonist, Pioglitazone, or Sulfonylureas) or GLP-1 analogue (e.g., Ozempic or Wegovy semaglutide, Mounjaro trizapatide) prescription medications within 6 months of visit 1 19. Steroid use within 30 days of visit 1 and throughout the study period 20. Unstable use of any prescription medication, where stable use is defined as no change in dose or medication type within 90 days of visit 1 21. Recent history of (within 12 months of screening; visit 1) or strong potential for alcohol or substance abuse.\n\nAlcohol abuse is defined as \\> 14 drinks per week (1 drink = 12 oz beer, 5 oz wine or 1 ½ oz distilled spirits) 22. Consumption of ergogenic-levels of dietary supplements that may affect muscle mass (e.g., creatine, HMB), insulin-like substances, or anabolic\u002Fcatabolic pro-hormones (e.g., DHEA) within 6 weeks prior to participation 23. Consumption of thyroid, androgenic, or other medications known to affect endocrine function 24.\n\nConsumption of medications known to affect protein metabolism (e.g., prescription-strength corticosteroids, non-steroidal anti-inflammatories, or acne medication) 25. Antibiotic use within 30 days of visit 1 and throughout the study period 26. Exposed to any non-registered drug product within 30 days of visit 1 27. Habitual users (i.e., daily or almost daily) of marijuana and hemp products, including CBD products. Occasional use (e.g. couple times a month) within 12 months of visit 1 is allowed but requires at least a 14 day washout prior to visit 1 and the participant must be willing to refrain from use during the study (sleep aids and topical lotions\u002Fcreams are allowed) 28. Allergy or hypersensitivity to local anesthetics, latex, or adhesives (bandages, medical tape, etc.) 29. Excess scarring after injury, including predisposition to hypertrophic scarring or keloid formation 30. History of excess bleeding after cut 31. Known allergy or sensitivity to any ingredients or potential allergens contained in the study product or standard meals 32. Physical activity limitations 33. Self-report history of fainting during routine blood draws or upon sight of blood 34.\n\nChronic or frequent dizziness or fainting and arm or leg weakness\u002Fnumbness 35. Self-report of blood donation totaling between 101-449mL of blood within 30 days prior to visit 1 or a blood donation of ≥ 450 mL within 56 days prior to visit 1, or plasma donations within 48 hours of visit 1. As well as any plans to donate blood or plasma during the study period 36. Any condition the Investigator believes would interfere with the participant's ability to provide informed consent or comply with the study protocol, which might confound the interpretation of the study results or put the person at undue risk","19 Years","40 Years",{"count":398,"type":23},20,[26],"The overall objective of this study is to determine the effects of ingesting protein that slowly releases amino acids into the blood vs. a control product on how our muscles regulate the synthesis of new proteins, termed muscle protein synthesis (MPS), in healthy volunteers.",[29],"2026-03-25",{"date":404,"type":43},"2026-03-30",{"date":295,"type":23},{"date":104,"type":23},{"name":408,"class":409},"VitaKey Inc.","INDUSTRY",{"id":411,"slug":412,"hasResults":12,"nctId":413,"briefTitle":414,"officialTitle":415,"acronym":4,"eligibilityCriteria":416,"healthyVolunteers":12,"sex":18,"minAge":417,"maxAge":418,"enrollmentInfo":419,"targetDuration":4,"studyType":198,"phases":4,"briefSummary":420,"conditions":421,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":426,"completionDateStruct":428,"leadSponsor":429,"locationsCount":51},"100373778","nutritional-status-of-patients-after-hematopoietic-stem-cell-transplantation-100373778","NCT04146870","Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation","A Survey of Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation","Inclusion Criteria:\n\n* Patients who undergo hematopoietic stem cell transplantation in the First Affiliated Hospital of Soochow University.\n* Having a life expectancy of more than 3 months\n\nExclusion Criteria:\n\n* Not willing to participate in the investigation\n* Age less than 15 years old or more than 80 years old","15 Years","80 Years",{"count":62,"type":23},"The main objectives of this study were :(1) to comprehensively and systematically evaluate the nutritional status of patients after hematopoietic stem cell transplantation. (2) to explore the effect of nutritional factors on the prognosis of patients treated by hematopoietic stem cell transplantation.",[29,422],"Hematopoietic Stem Cell Transplantation","2026-03-17",{"date":425,"type":43},"2026-03-19",{"date":427,"type":43},"2018-10-01",{"date":47,"type":23},{"name":430,"class":50},"The First Affiliated Hospital of Soochow University",{"id":432,"slug":433,"hasResults":12,"nctId":434,"briefTitle":435,"officialTitle":436,"acronym":4,"eligibilityCriteria":437,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":438,"targetDuration":4,"studyType":24,"phases":440,"briefSummary":441,"conditions":442,"keywords":447,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":452,"startDateStruct":453,"completionDateStruct":455,"leadSponsor":457,"locationsCount":51},"100629631","sleep-well-firefighters-an-app-based-program-to-improve-sleep-cognition-and-behavioral-health-in-firefighters-100629631","NCT07477184","Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters","Intervention to Improve Sleep, Cognition, and Behavioral Health in Firefighters","Inclusion Criteria based on self report:\n\n* Current CalFire Wildfire firefighter in Central Coast region or City of San Luis Obispo Firefighter (non-volunteer and not a primarily administrator status)\n* English Speaking\n* Have an iPhone \u002FiPad\n* Age \\>= 18\n* Self-reported interest in improving sleep functioning.\n\nExclusion Criteria:\n\n* none",{"count":439,"type":23},50,[26],"The purpose of this pilot study is to examine the feasibility and acceptability of an app-based sleep program designed to help firefighters improve their sleep.",[443,444,445,348,29,446],"Sleep Health","Stress","Anxiety","Cognition",[448,449,450,446],"Firefighters","Behavioral Sleep Health","Digital Health","2026-03-13",{"date":423,"type":43},{"date":454,"type":43},"2026-01-05",{"date":456,"type":23},"2026-09",{"name":458,"class":50},"California Polytechnic State University-San Luis Obispo",{"id":460,"slug":461,"hasResults":12,"nctId":462,"briefTitle":463,"officialTitle":463,"acronym":464,"eligibilityCriteria":465,"healthyVolunteers":17,"sex":466,"minAge":60,"maxAge":4,"enrollmentInfo":467,"targetDuration":4,"studyType":24,"phases":469,"briefSummary":470,"conditions":471,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":475,"lastUpdatePostDateStruct":476,"startDateStruct":478,"completionDateStruct":480,"leadSponsor":482,"locationsCount":484},"100571739","chime-comparing-health-interventions-for-maternal-equity-100571739","NCT06724172","CHIME: Comparing Health Interventions for Maternal Equity","CHIME","Inclusion Criteria:\n\n* Maternal age 18 years or older\n* Maternal gestational age ≤ 20 weeks with viable singleton pregnancy documented on first trimester ultrasound with an intention to continue pregnancy to term\n* Plans to continue receiving antenatal care at the recruitment site\u002Fnetwork\n* Maternal characteristics include at least one of the following:\n* Self identifies as Black\u002FAfrican American\n* Self identifies as Hispanic\u002FLatino\u002Fa\u002Fe\u002Fx\n* Insured by Medicaid\n* Maternal ability to speak English or Spanish\n* Completion of baseline data collection (maternal survey data, weight, and height measurement prior to randomization)\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years at baseline because of unique developmental differences of adolescents and regulations regarding age of consent\n* Underweight (BMI \\\u003C18 kg\u002Fm2) at pre-pregnancy period\n* Underlying disease\u002Ftreatment that might impact weight status (e.g., significant gastrointestinal conditions, major psychiatric disorders, and others at the discretion of the study clinician)\n* Unwillingness or inability to complete study visits or intervention components\n* Unwillingness or inability to commit to intervention components for self or infant, including plans to move more than 100-mile radius from recruitment site\n* Multiple gestations","FEMALE",{"count":468,"type":23},795,[26],"The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum.\n\nThe main question it aims to answer is which of the two multi-level, multi-component interventions has greater effectiveness in reducing maternal postpartum weight retention at 12-months postpartum.\n\nHypothesis (primary): Both multi-level, multi-component interventions will have greater effectiveness reducing maternal postpartum weight retention at 12-months postpartum than the usual care group.\n\nHypothesis (secondary): The community-based intervention will have greater effectiveness than the self-management intervention.\n\nParticipants will be asked to participate in one of the study interventions from early pregnancy until 12 months postpartum and complete five research visits. General procedures include completion of:\n\n* Questionnaires\n* Dietary recalls\n* In-depth interviews\n* Anthropometric measurements\n* Collection of blood via finger stick or blood panel",[472,29,473,474,204],"Obesity and Overweight","Chronic Disease","Diabetes","2026-03-03",{"date":477,"type":43},"2026-03-05",{"date":479,"type":43},"2026-01-22",{"date":481,"type":23},"2030-04-01",{"name":483,"class":50},"Stanford University",4,{"id":486,"slug":487,"hasResults":12,"nctId":488,"briefTitle":489,"officialTitle":490,"acronym":4,"eligibilityCriteria":491,"healthyVolunteers":17,"sex":18,"minAge":225,"maxAge":492,"enrollmentInfo":493,"targetDuration":4,"studyType":24,"phases":495,"briefSummary":496,"conditions":497,"keywords":500,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":505,"lastUpdatePostDateStruct":506,"startDateStruct":507,"completionDateStruct":508,"leadSponsor":509,"locationsCount":51},"100621380","evaluating-the-effects-of-nutritional-interventions-on-sleep-the-gut-microbiome-cognition-and-stress-100621380","NCT07369869","Evaluating the Effects of Nutritional Interventions on Sleep, the Gut Microbiome, Cognition, and Stress.","Evaluating the Effects of Nutritional Interventions on Sleep, the Gut Microbiome, Cognition, and Stress Following 28 Days Consumption in Adults Reporting Sub-clinical Sleep Deficits: A Randomised, Double-blind, Placebo-controlled, Three-arm Parallel Groups Trial.","INCLUSION CRITERIA\n\n* Participants must self-assess themselves as being in good health.\n* Aged 25 to 60 years at the time of randomisation\n* Fluent in English\n* Identify as a 'poor sleeper' as defined subjectively (i.e. poor sleep quality, unrefreshing sleep) and a total score of \\>5 on the Pittsburgh Sleep Quality Index (PSQI).\n\nEXCLUSION CRITERIA\n\n* Member of own household currently participating in this trial\n* Evidence of current or recent sleep disorders (e.g. sleep apnoea, insomnia, circadian rhythm disorders), taking any medication which exerts sedative effects, affects the CNS and\u002For sleep, or be currently unwell with any illness that affects sleep (i.e. disorders of the CNS). An initial screening for sleep disorders will be conducted using the Sleep Disorders Symptom Checklist-25 (SDS-CL; Klingman et al., 2017). If a participant reports positively to any of the 25 questions in terms of being affected for three nights per week, or more, this will be followed up using a clinical interview according to the International Classification of Sleep Disorders (ICSD-3) to exclude on the basis of a sleep disorder\n* History of seizures or epilepsy\n* Shift working or have a history of shift work within the previous six months\n* Currently, or within the previous 8 weeks, consuming any nutritional supplements.\n* Participation in any other intervention research trials\n* Sleeping at a location other than their usual residence more than two nights per week during participation\n* Travel across multiple time zones within the last three months or have planned travel across multiple time zones during the study\n* Current or recent mood disturbances or Axis I disorders (descriptions will be given)\n* Current misuse of alcohol and\u002For drugs\n* Current smoker\n* Recent (within the last 12 weeks) infection and\u002For use of antibiotic medication\n* Pregnant, seeking to become pregnant or lactating\n* Those using (including within the last 2 weeks) proton-pump inhibitors","65 Years",{"count":494,"type":23},68,[26],"This will be a double-blind, placebo-controlled, parallel-group trial. Participants who are poor sleepers will be randomised to receive one of two investigational supplements, or a placebo control supplement, over a 28-day period. At baseline and following 28 days of consumption, sleep quality, gut microbiome profiles, cognitive performance, and mood will be assessed. Sleep outcome measures will also be assessed throughout the supplementation period to monitor the time course of any observed changes. A final data set of at least 66 participants is expected.",[444,498,446,29,499],"Sleep","Microbiome",[501,502,503,504],"sleep","gut health","cognition","stress","2026-02-27",{"date":475,"type":43},{"date":270,"type":23},{"date":272,"type":23},{"name":510,"class":50},"Northumbria University",{"id":512,"slug":513,"hasResults":12,"nctId":514,"briefTitle":515,"officialTitle":516,"acronym":517,"eligibilityCriteria":518,"healthyVolunteers":12,"sex":18,"minAge":519,"maxAge":520,"enrollmentInfo":521,"targetDuration":4,"studyType":24,"phases":522,"briefSummary":523,"conditions":524,"keywords":528,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":533,"lastUpdatePostDateStruct":534,"startDateStruct":536,"completionDateStruct":538,"leadSponsor":540,"locationsCount":51},"100505073","delivering-food-resources--kitchen-skills-forks-to-adults-with-food-insecurity-and-hypertension-100505073","NCT05856591","Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension","Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension: An RCT","FoRKS","Inclusion Criteria:\n\n1. Fluent in English\n2. Marion County resident\n3. 35-75 years\n4. Systolic BP of ≥120 in prior 12 months\n5. Ability to see and read street signs (self report)\n6. Stable housing with independent access to kitchen, including functional stove or hotplate, oven, refrigerator, and freezer (self report)\n7. Activity independence per functional activities questionnaire (FAQ; \\\u003C3 responses of \"Require Assistance\" and 0 responses of \"Dependent\")\n8. Food insecurity per first two items of USDA 18-item survey with ≥ 1 response of \"Often true\" or \"Sometimes true\" \\[1) Within the past 12 months, you worried that your food would run out before you got the money to buy more; 2) Within the past 12 months, the food you bought just didn't last and you didn't have money to get more.\\] OR currently listed as food insecure in Eskenazi EMR; OR currently receiving SNAP benefits.\n9. normal cognition per six-item screener (SIS; score of ≥ 5)\n10. Mean systolic BP of ≥120 from 3 standard BP measurements taken by research staff following standardized wait periods.\n\nExclusion Criteria:\n\n1. lives in nursing home\n2. diagnosis of dementia or Alzheimer disease or mild cognitive impairment; Parkinson disease; brain tumor\u002Finfection\u002Fsurgery (within the last 10 years with residual symptoms and\u002For functional loss\u002Fdeficit, such as impaired learning, memory, or communication); psychosis, schizophrenia, or bipolar disorder\n3. ICD 10 code I11\u002Fhypertensive heart disease, ICD 10 code I12\u002Fhypertensive CKD, ICD 10 code I13\u002Fhypertensive heart disease and CKD, ICD 10 code I15, or ICD 10 code I16\n4. alcohol consumption ≥ 8 drinks per week for women, or ≥15 drinks per week for men\n5. drug use\u002Fabuse (excluding marijuana) per EMR\n6. moving out of area during study timeline\n7. scheduling conflicts with intervention schedule\n8. unwilling to use a touchscreen\n9. unwilling to be on video conferencing\n10. low communicative ability, functional status, or other disorders (examiner rated) that would interfere with interventions and assessments\n11. unable to provide informed consent","35 Years","75 Years",{"count":62,"type":23},[26],"The goal of this clinical trial is to determine the impact of a home-delivered foods and kitchen skills program on health and nutrition in adults with high blood pressure and food insecurity.\n\nResearchers will compare Food Resources \\& Kitchen Skills (FoRKS) and Enhanced Usual Care (EUC) to evaluate the effects on mean systolic blood pressure (SPB), HbA1c, food security and nutrition.\n\nParticipants will complete 24-hr blood pressure monitoring, standard blood pressure measurements, weight, finger stick for A1c point-of-care testing, and questionnaires.",[525,526,29,527],"Food Insecurity","Hypertension","Disease Management",[529,530,531,532],"randomized controlled trial","kitchen skills","diet","social determinants of health","2026-02-03",{"date":535,"type":43},"2026-02-05",{"date":537,"type":43},"2023-04-17",{"date":539,"type":23},"2027-07-30",{"name":541,"class":50},"Indiana University",{"id":543,"slug":544,"hasResults":12,"nctId":545,"briefTitle":546,"officialTitle":547,"acronym":4,"eligibilityCriteria":548,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":284,"enrollmentInfo":549,"targetDuration":4,"studyType":198,"phases":4,"briefSummary":551,"conditions":552,"keywords":555,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":560,"lastUpdatePostDateStruct":561,"startDateStruct":563,"completionDateStruct":565,"leadSponsor":566,"locationsCount":51},"100622006","characteristics-of-performance-in-collegiate-cheerleaders-and-dancers-100622006","NCT07378007","Characteristics of Performance in Collegiate Cheerleaders and Dancers","Body Composition and Characteristics of Performance in Collegiate Cheerleaders and Dancers","Inclusion Criteria:\n\n* Must be a part of either the Florida State University dance or cheer team\n* Sex: Female\n* Age: 18-30\n* BMI: Normal (18.5 - 24.9 kg\u002Fm2)\n\nExclusion Criteria:\n\n* Not biologically female\n* Have a diagnosed and unresolved eating disorder\n* Not weight stable (defined as a gain\u002Floss of more than \\~7.7 lbs in the past 2 months)\n* Participants who are pregnant or who become pregnant during the study",{"count":550,"type":23},65,"This study aims to investigate performance differences between collegiate cheerleaders and dancers classified as normal weight obese and those classified as normal weight lean. The study will assess differences in physical performance, lifestyle behaviors, muscle quality, and nutrition-related factors between groups. Performance testing, body composition assessment, and questionnaire-based measures will be used to characterize these relationships.",[553,554,29],"Low Energy Availability","Physical Performance",[556,557,558,559,29],"Body Composition","Energy Availability","Physical Fitness","Division I Collegiate Cheerleaders and Dancers","2026-01-28",{"date":562,"type":43},"2026-01-30",{"date":564,"type":43},"2025-08-03",{"date":325,"type":23},{"name":567,"class":50},"Florida State University",{"id":569,"slug":4,"hasResults":12,"nctId":570,"briefTitle":571,"officialTitle":572,"acronym":4,"eligibilityCriteria":573,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":4,"enrollmentInfo":574,"targetDuration":4,"studyType":198,"phases":4,"briefSummary":576,"conditions":577,"keywords":578,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":584,"lastUpdatePostDateStruct":585,"startDateStruct":587,"completionDateStruct":589,"leadSponsor":590,"locationsCount":51},"100619661","NCT07347522","Body Composition and Lifestyle Factors in ROTC","Associations Between Body Composition, Energy Availability, and Lifestyle Factors in Reserve Officer Training Corps Cadets","Inclusion Criteria:\n\n* currently enrolled as a Reserve Officer Training Corps Cadets\n* 18 years or older\n\nExclusion Criteria:\n\n* pregnancy\n* injuries preventing full participation in ROTC training or activities",{"count":575,"type":23},45,"This study aims to investigates the relationships between body composition, sleep, diet, and physical fitness in ROTC cadets. Further, it aims to evaluate the accuracy of body composition screening methods and identify lifestyle factors linked to performance. Methods include body composition testing, surveys, accelerometry, and fitness score collection from cadets.",[553,554,29],[579,580,581,582,583],"body composition","energy availability","physical fitness","Reserve Officer Training Corp","nutrition","2026-01-09",{"date":586,"type":43},"2026-01-16",{"date":588,"type":43},"2025-10-01",{"date":325,"type":23},{"name":567,"class":50},{"id":592,"slug":593,"hasResults":12,"nctId":594,"briefTitle":595,"officialTitle":596,"acronym":4,"eligibilityCriteria":597,"healthyVolunteers":17,"sex":18,"minAge":60,"maxAge":519,"enrollmentInfo":598,"targetDuration":4,"studyType":24,"phases":599,"briefSummary":600,"conditions":601,"keywords":603,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":607,"lastUpdatePostDateStruct":608,"startDateStruct":610,"completionDateStruct":612,"leadSponsor":613,"locationsCount":4},"100619353","effects-of-sulforaphane-supplementation-on-athletic-performance-100619353","NCT07343518","Effects of Sulforaphane Supplementation on Athletic Performance","Effects of Sulforaphane Supplementation on Athletic Performance: a Double-blinded Randomized Crossover Study","Inclusion Criteria:\n\n* Physically active individuals (engaging in exercise 3 or more times per week)\n\nExclusion Criteria:\n\n* Individuals that experience musculoskeletal injuries or have experienced in the past 3 months",{"count":398,"type":23},[26],"Considering the promising effects observed and the scarce and incipient scientific background of SFN in sports, the present study aims to evaluate the effects of SFN supplementation on fatigue, EIMD and recovery in trained individuals. In particular, outcomes such as time to exhaustion (TTE), and perceptual questionnaires of muscle soreness, recovery, and fatigue will be assessed, aiming to explore the effectiveness of SFN.",[29,602],"Sports",[604,605,606],"sulforaphane","fatigue","athletic performance","2026-01-06",{"date":609,"type":43},"2026-01-15",{"date":611,"type":23},"2026-01-02",{"date":325,"type":23},{"name":614,"class":50},"University of Maia",{"id":616,"slug":617,"hasResults":12,"nctId":618,"briefTitle":619,"officialTitle":620,"acronym":621,"eligibilityCriteria":622,"healthyVolunteers":17,"sex":18,"minAge":623,"maxAge":624,"enrollmentInfo":625,"targetDuration":4,"studyType":198,"phases":4,"briefSummary":627,"conditions":628,"keywords":635,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":607,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":650,"locationsCount":51},"100517522","impact-of-diet-and-nutrition-on-growth-and-development-in-young-children-100517522","NCT06018636","Impact of Diet and Nutrition on Growth and Development in Young Children","Dietary Intake\u002FPatterns, Nutritional Status and Their Association With Growth and Development of Children From Remote, Agropastoral Communities of District Swat, Pakistan","DIGEST","Inclusion Criteria:\n\n* Households living in the area from the last two 2 years.\n* Households having infants or young children ≤ years.\n* Households planning to reside in the same area for the next 1 year.\n\nExclusion Criteria:\n\n* Children with any co-existent systemic diseases, confirmed from medical records.\n* Children on continuous medications for any medical issue.\n* Physically or mentally handicapped children","1 Day","24 Months",{"count":626,"type":23},832,"The association between nutrition in early life and its long-term health consequences has long been known. However, there is a scarcity of scientific evidence on how nutritional status affects child growth and development in remote, rural agro-pastoral communities with distinct dietary intake habits, geographical location, socio-economic status, and cultures.",[29,629,630,631,632,633,634],"Growth","Development","Stunting","Wasting","Obesity","Child Development",[636,637,629,638,639,640,641,642,643],"Nutritional status","Malnutrition","Cognitive Development","Anthropometry","Agropastoral","remote","rural","Urban",{"date":645,"type":43},"2026-01-08",{"date":647,"type":43},"2023-06-28",{"date":649,"type":23},"2028-09-30",{"name":651,"class":50},"Khyber Medical University Peshawar",{"id":653,"slug":654,"hasResults":12,"nctId":655,"briefTitle":656,"officialTitle":657,"acronym":658,"eligibilityCriteria":659,"healthyVolunteers":17,"sex":18,"minAge":660,"maxAge":661,"enrollmentInfo":662,"targetDuration":4,"studyType":24,"phases":664,"briefSummary":665,"conditions":666,"keywords":673,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":677,"lastUpdatePostDateStruct":678,"startDateStruct":679,"completionDateStruct":681,"leadSponsor":683,"locationsCount":51},"100616529","the-effect-of-piomi-and-chronobiological-nutrition-on-readiness-for-feeding-full-transition-to-oral-feeding-and-body-weight-100616529","NCT07306793","The Effect of PIOMI and Chronobiological Nutrition on Readiness for Feeding, Full Transition to Oral Feeding and Body Weight","The Effect of Oral Motor Intervention and Chronobiological Approach to Feeding Models Applied to Preterm Infants on Infants' Readiness to Feed, Transition to Total Oral Feeding, and Body Weight","PIOMI","Inclusion Criteria:\n\n* Preterm infants with a postnatal age of 29-33 weeks,\n* Whose vital signs and clinical condition have been stable for at least 24 hours,\n* Whose APGAR score at 1 and 5 minutes (Activity-Pulse-Grimace-Appearance-Respiration) is 4 or higher.\n\nExclusion Criteria:\n\n* Infants with major congenital anomalies (such as congenital heart disease, cleft palate, cleft lip) or birth trauma,\n* Infants with RDS,\n* Infants diagnosed with asphyxia,\n* Infants with intraventricular hemorrhage,\n* Infants with Neonatal Withdrawal Syndrome,\n* Infants with Fetal Alcohol Syndrome,\n* Infants included in the study group who develop any complications or whose stable condition deteriorates during the follow-up period,\n* Infants with feeding intolerance or who are interrupted from feeding for more than 48 hours,\n* Infants who develop sepsis,\n* Infants who develop necrotizing enterocolitis,\n* Infants receiving mechanical ventilation support,\n* Infants who receive narcotic analgesia or sedation,","29 Weeks","33 Weeks",{"count":663,"type":23},54,[26],"This is a randomized controlled experimental study evaluating the effects of oral motor intervention and chronobiological approach to feeding model applied to preterm infants on feeding readiness, transition to total oral feeding and body weight.",[667,668,669,670,671,29,672],"Neonatal İntensive Care","Nutrition With A Chronobiological Approach","Readiness For Feding","Body Weight","Breast Milk","Premature Birth",[667,668,669,670,674,675,676],"Transitioning To Total Oral Feeding","Premature Infant Oral Motor Intervention (PIOMI)","Prematüre","2026-01-01",{"date":607,"type":43},{"date":680,"type":43},"2025-03-01",{"date":682,"type":23},"2026-09-30",{"name":684,"class":50},"Aydin Adnan Menderes University",{"id":686,"slug":687,"hasResults":12,"nctId":688,"briefTitle":689,"officialTitle":690,"acronym":4,"eligibilityCriteria":691,"healthyVolunteers":12,"sex":18,"minAge":60,"maxAge":418,"enrollmentInfo":692,"targetDuration":4,"studyType":24,"phases":694,"briefSummary":695,"conditions":696,"keywords":697,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":699,"lastUpdatePostDateStruct":700,"startDateStruct":702,"completionDateStruct":704,"leadSponsor":706,"locationsCount":51},"100616576","web-based-platform-for-nutrition-management-in-patients-with-cancer-100616576","NCT07307404","Web-based Platform for Nutrition Management in Patients With Cancer","Web-based Platform for Nutrition Management in Patients With Cancer: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Pathologically confirmed malignant tumor;\n* PG-SGA score of 4-9 points;\n* Age: ≥18 years, with an expected survival time of more than 1 year;\n* Possesses adequate cognitive and reading abilities to complete questionnaires and use the APP.\n\nExclusion Criteria:\n\n* Presence of neurological or psychiatric disorders affecting cognitive function, including central nervous system metastasis of tumors;\n* Suffering from conditions severely impacting digestion, metabolism, or food intake;\n* Patients in the cachexia stage or refractory cachexia phase.",{"count":693,"type":23},84,[26],"It is crucial to promptly identify nutritional issues in these patients within the community and provide them with dietary guidance, nutritional counseling, and support. This study will be conducted in communities in Chengdu, Sichuan. Community management teams will register oncology patients, collecting information such as demographic data, tumor type, stage, specific treatment plan, treatment hospital, regularity of hospital admissions, and frequency of independent smartphone use. Registered patients will be screened based on inclusion and exclusion criteria. For those who meet the criteria, the community management team will contact them and recommend the use of a dedicated app developed by the research team. An initial nutritional assessment will also be conducted. Patients identified with nutritional risks will be directly referred to the research team's clinical nutritionists for face-to-face consultations. After additional tests, such as body composition analysis, necessary nutritional education and stepwise nutritional interventions will be provided. These patients will also use the app for dietary monitoring and nutritional guidance. For patients without nutritional risks, the app will be recommended for daily questionnaire completion and activity tracking.",[29],[698],"cancer","2025-12-14",{"date":701,"type":43},"2025-12-29",{"date":703,"type":23},"2025-12-30",{"date":705,"type":23},"2027-04-30",{"name":707,"class":50},"Xingchen Peng"]