[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nutritional-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nutritional-intervention":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,48,71,100,127,154],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100521924","ketone-conferred-resiliency-against-sleep-restriction-with-nutritional-intervention-100521924",false,"NCT06075914","Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.","Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention (STAK - Sleep + Feed)","Inclusion Criteria:\n\n* Healthy, 18-40 years old.\n* BMI: 20-35 kg\u002Fm2\n* Sleep at least 7h per night.\n* Willing to participate in \\~9-weeks of testing and provided food.\n* Willing to adhere to all study procedures.\n\nExclusion Criteria:\n\n* \\\u003C18 or \\>40 years of age\n* \\>35 body mass index (BMI).\n* Diagnosed sleeping disorders (i.e., sleep apnea, insomnia).\n* Gastrointestinal disorders or food allergies that would interfere with consuming the study supplements.\n* Drink alcohol in excess of 3 drinks\u002Fday or 14 drinks\u002Fweek\n* Have any conditions or contraindications to blood draws.\n* Have been diagnosed with diabetes, liver, kidney, or other metabolic or endocrine dysfunction, or use diabetic medications other than metformin\n* Currently consume a low carbohydrate or ketogenic diet or have done so in the last 3 months\n* Have experienced weight loss of \\>10% of your body weight within the last 6 months\n* Are pregnant, lactating, or planning on becoming pregnant during the study\n* Have any major psychiatric disorders (e.g., schizophrenia, bipolar disorder)",true,"ALL","18 Years","40 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks. Ketogenic supplementation is speculated to alleviate some sleep deprivation issues via action of ketones. Ketones are small molecules that appear in the blood when following a ketogenic diet or consuming ketone supplements. The goal of this project is to find out if diet and\u002For ketones can improve sleep deprivation detriments over 5 days of sleep restriction (-50% from habitual sleep).",[28,29],"Sleep Deprivation","Nutritional Intervention",[31,32,33,34],"Ketogenic Diet","Mediterranean Diet","Ketone Esters","Placebo","RECRUITING","2026-06-23",{"date":38,"type":39},"2026-06-24","ACTUAL",{"date":41,"type":39},"2023-05-01",{"date":43,"type":22},"2027-02",{"name":45,"class":46},"Ohio State University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":47},"100572202","standardized-nutritional-management-of-pediatric-patients-with-solid-tumors-100572202","NCT06730204","Standardized Nutritional Management of Pediatric Patients With Solid Tumors","Nutrition Strategies and Malnutrition Assessment Management Systems for Preventing Malnutrition in Children With Solid Tumors: an Exploratory Intervention Study","1. Male and female, age 0-18 years old\n2. Pathological diagnosis is malignant solid tumor with untreated initial onset",{"count":56,"type":22},400,[25],"The purpose of this study is to establish a standardized nutrition intervention procedure for children with solid tumors, and to explore the effectiveness and clinical applicability of standardized nutrition management and short peptide-based enteral nutrition intervention for improving the nutritional status of children with malignant solid tumors.\n\nAfter admission, patients in the intervention group will receive standardized nutrition management provided by a nutrition support team composed of dietitians, nutritionists, clinicians, and nursing teams. Basic information, including diet, enteral and parenteral nutrition, nutritional status and clinical data, will be collected during the study.",[60,61,29],"Tumor, Solid","Children","2026-03-13",{"date":64,"type":39},"2026-03-16",{"date":66,"type":39},"2023-07-01",{"date":68,"type":22},"2026-12-31",{"name":70,"class":46},"Children's Hospital of Fudan University",{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":16,"sex":17,"minAge":78,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":23,"phases":81,"briefSummary":82,"conditions":83,"keywords":88,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":47},"100601362","nutrition-to-support-postoperative-recovery-100601362","NCT07109505","Nutrition to Support Postoperative Recovery","Comparison of Clinical and Patient Centered Outcomes: Postoperative Multi-nutrient Meal Plus Enhanced Recovery vs. Enhanced Recovery Alone","Inclusion Criteria:\n\n* patients \\>=70 years old having major orthopedic or abdominal surgery, defined as a procedure with a planned inpatient stay of at least one night.\n\nExclusion Criteria:\n\n* emergency surgery, diagnosis of dementia or major psychiatric diagnosis such as schizophrenia, Parkinson's disease, inability to consent for themselves, unwilling or unable to complete all study requirements and measurements, any known food allergy, dislike of shake flavor(s), unwilling or unable to tolerate caffeine in shake, unable to take oral nutrition, BMI \\>45, diagnosis of an eating disorder, insulin dependent diabetes.\n* MRI procedure eligibility will be assessed using the DHMC Department of Radiology's standard MRI Safety Checklist, which screens for potential contraindications to MRI scanning such as metal in the body, possible exposure to metal in the eyes, pregnancy, and claustrophobia. Any individual with a contraindication to MRI scanning will not be eligible to participate in the optional MRI component.","70 Years",{"count":80,"type":22},100,[25],"Older surgical patients commonly have malnutrition, and there is evidence these patients have increased risk for poor physical and brain recovery after surgery and anesthesia. There are scientific-based recommendations to provide nutritional supplements to support recovery. However, to date these recommendations do not address a broad group of nutrients likely to reverse common deficiencies. Team members have created a palatable, broad-spectrum and stable nutritional shake that we will give to patients after surgery. We propose to test the nutritional shake in frail older surgical patients at Dartmouth Health to determine if a nutrition shake provided after surgery improves recovery of physical function and cognitive abilities. Half the patients will receive the shake and the other will receive the standard of care postoperative nutritional instructions after surgery. We will collect information regarding physical function and cognitive abilities of all the patients while in the hospital and 90 days after surgery. We will use this data to apply for funding for a powered randomized trial to determine the role of nutrition in optimizing physical and cognitive recovery from surgery in older patients.",[84,85,86,87,29],"Postoperative Care","Postoperative Complications","Cognition","Nutritional Assessment",[89,90,86],"Nutrition","Postoperative","2026-02-10",{"date":93,"type":39},"2026-02-11",{"date":95,"type":39},"2025-12-10",{"date":97,"type":22},"2026-09-30",{"name":99,"class":46},"Dartmouth-Hitchcock Medical Center",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":23,"phases":110,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":47},"100526979","early-nutritional-intervention-in-patients-with-cancer-100526979","NCT06141785","Early Nutritional Intervention in Patients With Cancer","Early Nutritional Intervention to Prevent Malnutrition in Patients With Cancer Receiving Palliative Chemotherapy in an Outpatient Setting","NICOS","Inclusion Criteria:\n\n* patients who are newly diagnosed with lung, colorectal, ovarian, or pancreatic cancer.\n* patients treated with first-line palliative chemotherapy\n* patients who are Danish speaking\n* patients ≥18 years of age\n* patients who are cognitive well-functioning\n\nExclusion Criteria:\n\n* Patients not using electronic mail\n* patients with dementia\n* patients not able to comply with the study protocol",{"count":109,"type":22},200,[25],"The goal of this intervention study is to study the effect of nutritional interventions in patients with cancer receiving palliative chemotherapy. The main question it aims to answer is: Does early nutritional interventions affect body weight, quality of life, survival, muscle mass, performance status, physical function, nutritional risk and treatment tolerance in patients with cancer receiving palliative chemotherapy? Researchers will compare patients receiving the intervention to a historical control cohort following current clinical practice.",[29,113,114],"Cancer","Malnutrition",[116,117,113,114,89],"Nutritional interventions","Dietetics","2025-12-17",{"date":120,"type":39},"2025-12-24",{"date":122,"type":39},"2024-06-01",{"date":124,"type":22},"2027-01-29",{"name":126,"class":46},"Gødstrup Hospital",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":135,"maxAge":4,"enrollmentInfo":136,"targetDuration":4,"studyType":23,"phases":138,"briefSummary":139,"conditions":140,"keywords":4,"overallStatus":144,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":4},"100597296","staircase-nutritional-intervention-for-elderly-patients-undergoing-spinal-fusion-surgery-100597296","NCT07056647","Staircase Nutritional Intervention for Elderly Patients Undergoing Spinal Fusion Surgery","A Prospective Multicenter Randomized Controlled Trial of a Staircase Nutritional Intervention Strategy Versus Conventional ERAS Diet Management for Elderly Patients Undergoing Spinal Fusion Surgery","SNIEPUSFS","Inclusion Criteria:\n\n* Age and Gender: Aged ≥ 75 years, regardless of gender. Surgery Type: Scheduled for elective spinal fusion surgery, including but not limited to lumbar, thoracic, and cervical spinal fusion surgeries. The surgeries are aimed at treating spinal degenerative diseases (such as lumbar disc herniation, lumbar spinal stenosis, etc.), spinal trauma, spinal deformities, etc.\n\nNutritional Status: Willing and able to cooperate with nutritional assessments (such as Mini - Nutritional Assessment, MNA), and patients with any level of nutritional risk are included.\n\nPhysical Condition: American Society of Anesthesiologists (ASA) physical status classification Ⅰ - Ⅲ, meaning the physical condition is relatively tolerable for surgery, without severe failure of important organs such as the heart, lungs, liver, and kidneys, and without uncontrolled severe hypertension, diabetic ketoacidosis, and other acute complications.\n\nCognitive and Communication Ability: Possessing basic cognitive and communication abilities, being able to understand the purpose, process, and relevant requirements of the study, and signing a written informed consent form.\n\nLife Expectancy: With a life expectancy of more than 1 year to facilitate long - term postoperative follow - up and assessment.\n\nExclusion Criteria:\n\n* Severe Underlying Diseases: Presence of severe heart failure (New York Heart Association functional class Ⅳ), end - stage liver disease (such as decompensated liver cirrhosis with severe ascites, hepatic encephalopathy, etc.), end - stage renal disease (requiring maintenance dialysis treatment), end - stage malignant tumors, and other serious underlying diseases that severely affect life and health and recovery.\n\nPsychiatric and Neurological Diseases: Suffering from severe mental illnesses (such as schizophrenia, major depressive disorder in the acute phase and unable to cooperate with the study), Alzheimer's disease and unable to understand the content of the study, and serious neurological diseases (such as long - term bedridden patients with severe stroke and impaired consciousness).\n\nContraindications to Nutritional Supplements: Allergic to the components of the nutritional supplements involved in the study (such as enteral nutrition powder mixture, low - sugar whole - protein enteral nutrition powder, etc.) or having severe intolerance.\n\nRecent Special Situations: Having a history of severe trauma or major surgery (other than the planned spinal fusion surgery) in the past 3 months; having a history of severe gastrointestinal diseases such as gastrointestinal bleeding and intestinal obstruction in the past 1 month.\n\nOthers: Currently participating in other clinical trials that may affect the results of this study; having insurmountable compliance problems (such as failure to take nutritional supplements on time, refusal of follow - up, etc.).","75 Years",{"count":137,"type":22},88,[25],"The goal of this prospective multicenter randomized controlled clinical trial is to evaluate the efficacy of a staircase nutritional intervention in reducing postoperative complications and improving long-term functional recovery in elderly patients aged ≥75 years scheduled for spinal fusion surgery. The main questions it aims to answer are:\n\n1. Does the staircase nutritional intervention reduce the 30-day postoperative complication rate, as measured by the Comprehensive Complication Index (CCI), compared to conventional ERAS diet management?\n2. Does the staircase nutritional intervention improve 1-year functional recovery, as assessed by Oswestry\u002FNeck Disability Index (ODI\u002FNDI) and health-related quality of life (EQ-5D), compared to conventional ERAS diet management?\n\nResearchers will compare the intervention group receiving MNA - based staircase nutritional intervention (including 14-day preadmission oral nutritional supplementation, perioperative personalized nutritional support, and postdischarge continuous management) combined with surgery-specific prehabilitation training to the control group receiving conventional ERAS diet management to see if the former leads to better clinical outcomes and long-term functional recovery.\n\nParticipants will\n\nUndergo randomization: Be randomly assigned to either the intervention group or the control group.\n\nReceive assigned interventions:\n\nControl group: Receive conventional ERAS diet management, including preadmission nutritional education and early postoperative oral intake.\n\nIntervention group: Undergo MNA - based staircase nutritional intervention and surgery-specific prehabilitation training.\n\nParticipate in follow-up: Complete short-term (within 90 days postoperatively) and long-term (6 and 12 months postoperatively) follow-up assessments, including laboratory tests, functional evaluations, and satisfaction surveys.",[29,141,142,143],"Spinal Surgery","Elderly","Enhanced Recovery After Surgery","NOT_YET_RECRUITING","2025-06-29",{"date":147,"type":39},"2025-07-09",{"date":149,"type":22},"2025-07-01",{"date":151,"type":22},"2028-01-31",{"name":153,"class":46},"Xuanwu Hospital, Beijing",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":16,"sex":17,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":23,"phases":166,"briefSummary":167,"conditions":168,"keywords":169,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":179,"leadSponsor":181,"locationsCount":47},"100581610","the-effect-of-ingesting-a-novel-algae-protein-source-on-rested-and-exercised-muscle-protein-synthesis-rates-in-older-adults-100581610","NCT06852547","The Effect of Ingesting a Novel Algae Protein Source on Rested and Exercised Muscle Protein Synthesis Rates in Older Adults.","Ingestion of a Novel Algae Protein Source on Rested and Post Exercise Muscle Protein Synthesis Rates.","CALM","Inclusion Criteria:\n\nMales and Females BMI 18.5 - 30 kg\u002Fm2 Aged 65-80 years Recreationally Active\n\nExclusion Criteria:\n\nBody mass index (BMI) \\\u003C18.5 or \\>30 kg\u002Fm2 Any metabolic impairments Any cardiovascular impairments High blood pressure (≥140\u002F90 mmHg) Any gastrointestinal disorders Any medications known to affect protein and\u002For amino acid metabolism A personal or family history of epilepsy, seizures or schizophrenia, motor disorder Chronic over the counter use of pharmaceuticals (\\> 1 month) Allergic to any of the whole foods included in the study","65 Years","80 Years",{"count":165,"type":22},15,[25],"To assess the rested and postexercise muscle protein synthetic response following the ingestion of a flavourless algae protein source compared with whey protein in older adults.",[29],[170,171,172,173],"novel protein","protein synthesis","older adults","alge","2025-02-24",{"date":176,"type":39},"2025-02-28",{"date":178,"type":39},"2025-02-23",{"date":180,"type":22},"2026-03-01",{"name":182,"class":46},"University of Exeter"]