[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"oa\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:oa":108},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100617256","value-of-adding-t2-mapping-routine-mri-in-assessment-of-knee-articular-cartilage-early-osteoarthritis-100617256",false,"NCT07316257","Value of Adding T2 Mapping Routine MRI in Assessment of Knee Articular Cartilage Early Osteoarthritis","Value of Adding T2mapping Sequence to Routine MRI Protocol in Assessment of Knee Articular Cartilage in Early Osteoarthritis","T2 mapping OS","Inclusion Criteria:\n\n* patients with clinical evidence of osteoarthritis\n\nExclusion Criteria:\n\n* • contraindications for MRI such as claustrophobia, heart pacemaker and ferromagnetic implants\n\n  * patients in which the misaligned images or distortions due to motion artifacts made the interpretation of the MRI unreliable.\n  * Patients with previous knee operation",true,"ALL","20 Years","50 Years",{"count":22,"type":23},70,"ESTIMATED","OBSERVATIONAL","This work aims at elucidating the role of MRI complementary T2 mapping in assessment of the articular knee cartilage for improving sensitivity of detection of early stage of osteoarthritis",[27,28,29],"Osteearthritis","OA","OA Knee","NOT_YET_RECRUITING","2025-12-30",{"date":33,"type":34},"2026-01-05","ACTUAL",{"date":36,"type":23},"2026-01-01",{"date":38,"type":23},"2027-02-01",{"name":40,"class":41},"Assiut University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":18,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":64,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100570627","kinematic-alignment-in-total-knee-arthroplasty---a-double-blind-randomised-controlled-trial-between-robotic-and-caliper-based-techniques-100570627","NCT06709703","Kinematic Alignment in Total Knee Arthroplasty - a Double-blind Randomised Controlled Trial Between Robotic and Caliper-based Techniques","L'Alignement cinématique Dans Les prothèses de Totales de Genou : un Essai randomisé contrôlé à Double Insu Comparant la Robotique Aux Instruments Traditionnels","Inclusion Criteria:\n\n* Patient aged 18 or above\n* Patient being consented for a primary total knee arthroplasty (TKA)\n* The primary TKA is planned to be done with kinematic alignment\n* All pre-operative alignments are included\n\nExclusion Criteria:\n\n* Revision TKA (including revision of unicompartimental knee arthroplasty into total knee arthroplasty with primary components). TKA being done in the setting of previous femur or tibia fracture or osteotomy are however included.\n* No available adequate pre-operative imaging\n* Patient who does want to be randomized of the two groups\n* At the discretion of the surgeon, if the patient's pathology or particular anatomy precludes the use of kinematic alignment technique, robotic surgery, or traditional instrument TKA.","18 Years",{"count":51,"type":23},200,"INTERVENTIONAL",[54],"NA","Knee replacement surgery is a surgery designed to treat severe arthritis of the knee. However, as many as 20% of patients are not satisfied with the results of their surgery. To place the knee replacement in correct position, the kinematic alignment method, which tries to reproduce the patient normal anatomy, has shown promise in improving the satisfaction after knee replacement surgery. It is not known if using a robotic arm to assist in surgery is better than the traditional method when trying to recreate kinematic alignment.\n\nThe goal of this study is to learn if robotic assisted surgery is better than traditional method for knee replacement done using kinematic alignment. The main questions the study tries to answer are:\n\n1. Do the radiographs of kinematic knee replacement surgeries done with robotic assistance show better alignment than radiographs of kinematic knee replacements done with the traditional method?\n2. Does robotic assisted kinematic knee replacement give better function to patients than traditional knee replacement done with kinematic alignment?\n3. Does robotic assisted kinematic knee replacement decrease pain, improve knee movement and improve knee stability better than traditional knee replacement done with kinematic alignment?\n4. Are there more complications with robotic assisted kinematic knee replacement in comparison to traditional kinematic knee replacement?\n5. How long long does it take a surgeon to become good a performing a kinematic knee replacement using robotic assistance? Researchers will compare knee replacements done using a robotic to make the bone cuts, and compare it to the usual method using guides and manual instruments. All the knee replacements will be done using the kinematic alignment and with the same type of knee replacement prothesis.\n\nParticipants will:\n\n* Have a knee replacement done with the kinematic alignment technique by an experienced surgeon, with or without robotic assistance during the surgery.\n* Visit the clinic before surgery, six weeks after surgery, three months, six months, twelve months and twenty-four months after the surgery.\n* Fill questionnaire, have their knee examined and have radiographs of their knee done at each visit.",[57,58,59,60,28,29,61,62,63],"Arthritis","Arthritis (Knee)","Osteoarthritis","Osteoarthritis Knee Pain","OA Knee Pain","Osteoarthritis of Knee","Gonarthrosis; Primary",[65,66,67,68,69,70,71,72,73],"osteoarthritis","arthritis","knee osteoarthritis","knee OA","knee arthritis","total knee replacement","robotic","kinematic alignment","patient-specific surgery","2024-11-25",{"date":76,"type":34},"2024-11-29",{"date":78,"type":23},"2025-02",{"date":80,"type":23},"2028-09",{"name":82,"class":41},"Université de Sherbrooke",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":17,"sex":18,"minAge":49,"maxAge":90,"enrollmentInfo":91,"targetDuration":93,"studyType":24,"phases":4,"briefSummary":94,"conditions":95,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":107},"100556655","a-randomized-study-on-sagittal-angle-differences-in-lower-limbs-between-normal-individuals-and-osteoarthritis-patients-100556655","NCT06527924","A Randomized Study on Sagittal Angle Differences in Lower Limbs Between Normal Individuals and Osteoarthritis Patients","A Randomized Controlled Trial of the Difference in Sagittal Angle of the Lower Limbs Between Healthy Individuals and Patients With Osteoarthritis","Inclusion Criteria:\n\n1. The age ranged from 18 to 80 years old;\n2. Non OA examinees of lower limb sagittal EOS in the General Hospital of Chinese PLA;\n3. OA patients with sagittal EOS were photographed in the Department of joint surgery, General Hospital of Chinese PLA;\n4. Patients are willing to participate in the study and sign written informed consent.\n\nExclusion Criteria:\n\n1. People unable to conduct EOS inspection;\n2. Combined with knee meniscus injury, anterior cruciate ligament injury and other diseases that may affect the sagittal force line of the knee joint\n3. Combined with other diseases that may affect the study\n4. Patients refused to use their imaging data and knee score for this study","80 Years",{"count":92,"type":23},400,"3 Years","With China gradually entering an aging society, the proportion of the elderly population is gradually increasing, and the number of patients with knee disease is also increasing year by year. Total knee arthroplasty is one of the effective methods for the treatment of joint disease, which can effectively relieve knee pain, restore function and improve the quality of life. The goal of total knee arthroplasty is to relieve pain, restore function and obtain a long service life. Whether total knee arthroplasty can obtain good alignment is very important for the postoperative recovery of patients. The alignment of lower limb sagittal position is of great significance for evaluating whether the crowd is straightened or not, and can also evaluate and guide the TKA in sagittal position. At present, there are few studies on the sagittal position of the lower limb, and there is no clear definition of whether the lower limb is extended in the sagittal position. At the same time, there is no clear method to evaluate whether the lower limb is extended in the sagittal position in normal people and patients with OA. Therefore, it is urgent to develop a classification standard for the sagittal extension of the lower limb, which can be used in clinical evaluation and TKA operation evaluation. This study will be carried out in the first medical center of the Chinese PLA General Hospital, and a total of about 400 people are expected to be enrolled.",[28,96,97],"TKA","EOS","2024-08-04",{"date":100,"type":34},"2024-08-06",{"date":102,"type":23},"2024-09-01",{"date":104,"type":23},"2026-09-01",{"name":106,"class":41},"Chinese PLA General Hospital",1,""]