[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obesity-childhood\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obesity-childhood":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,31,0,25,[9,47,74,104,125,147,172,195,225,247,272,303,336,361,385,406,439,472,500,530,557,577,605,633,664],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":24,"studyType":25,"phases":4,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100584679","breastmilk-in-response-to-a-bout-of-exercise-100584679",false,"NCT06892483","Breastmilk in Response to a Bout of Exercise","Breastmilk Composition in Response to a Bout of Exercise","Exclusion Criteria:\n\n* Active coronary artery disease or heart failure.\n* Participation in a structured exercise program ≥ 1 day\u002Fweek in the \"inactive\" subcohort or \\\u003C 3 days per week in the \"active\" subcohort.\n* A known medical condition that in the judgment of the investigator might interfere with the completion of the protocol such as the following examples:\n\n  * Abnormal liver function test results (Transaminase \\>2 times the upper limit of normal\n  * Abnormal renal function test results (calculated GFR \\\u003C60 mL\u002Fmin\u002F1.73m2);\n  * If on antihypertensive, thyroid, anti-depressant or lipid lowering medication, lack of stability on the medication for the past 2 months prior to enrollment in the study\n  * Uncontrolled thyroid disease (TSH undetectable or \\>10 mlU\u002FL); testing required within three months prior to admission for subjects with a goiter, positive antibodies, or who are on thyroid hormone replacement, and within one year otherwise\n  * Abuse of alcohol or recreational drugs\n  * Active tobacco smoking within the past 3 months\n  * Infectious process not anticipated to resolve prior to study procedures (e.g. meningitis, pneumonia, osteomyelitis).\n  * Uncontrolled arterial hypertension (Resting diastolic blood pressure \\>90 mmHg and\u002For systolic blood pressure \\>160 mmHg) at the time of screening.\n  * A recent injury to body or limb, muscular disorder, use of any medication, any carcinogenic disease, or other significant medical disorder if that injury, medication or disease in the judgment of the investigator will affect the completion of the protocol\n  * Active pregnancy\n  * Restrictions on Use of Other Drugs or Treatments:\n\n    * Any other medication believed to be a contraindication to the subject's participation.",true,"FEMALE","18 Years","45 Years",{"count":22,"type":23},60,"ESTIMATED","1 Month","OBSERVATIONAL","The purpose of this study is to unveil the mechanistic benefits of a bout of postpartum maternal exercise on infant health that are provided by breastmilk.",[28,29,30],"Infant Development","Obesity, Childhood","Diabetes, Childhood-Onset",[32,33],"Breast milk","Postpartum exercise","RECRUITING","2026-06-19",{"date":37,"type":38},"2026-06-24","ACTUAL",{"date":40,"type":38},"2025-04-21",{"date":42,"type":23},"2028-09-25",{"name":44,"class":45},"Mayo Clinic","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":46},"100591208","phase-4-glp-1-plus-lifestyle-for-overall-wellness-find-your-way-forward-100591208","NCT06977438","GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward","GLOW (GLP-1 Plus Lifestyle for Overall Wellness)","GLOW","Inclusion Criteria:\n\n* Aged 12 to \\\u003C 18 years at screening\n* BMI \\>\u002F= 95th percentile based on age and sex at screening\n* Provide release of information for established primary health provider\n* Own a device capable of connecting to the virtual platform sessions with video\n\nExclusion Criteria:\n\n* Diabetes (type 1 or 2) due to safety concerns about proper surveillance of glycemic control virtually\n* HbA1c \\>\u002F= 6.5%\n* Current or recent (\\\u003C 6 months prior to screening) use of FDA-approved obesity medications\n* Previous metabolic\u002Fbariatric surgery or metabolic\u002Fbariatric surgery planned during the study period\n* Hypertriglyceridemia (TG \\>\u002F= 500 mg\u002FdL)\n* Any past or current diagnosis of an eating disorder (i.e. anorexia nervosa, atypical anorexia nervosa, bulimia nervosa)\n* Major psychiatric disorder (e.g. schizophrenia, bipolar disorder)\n* Unstable clinically-diagnosed depression, defined as requiring psychiatric hospitalization in the last six months)\n* History of suicide attempt\n* History of suicidal ideation or self-harm within 30 days of screening\n* Patient Health Questionnaire (PHQ-9) score \\>\u002F= 15 at screening\n* Current pregnancy, breast feeding, or plans to become pregnant\n* Females refusing to use effective contraception\n* Diagnosis of monogenic obesity due to mutations in POMC, PCSK1, or LEPR\n* Diagnosis of syndromic obesity including, but not limited to, Bardet Biedl or Prader-Willi Syndrome\n* History of cholelithiasis without cholecystectomy\n* History of pancreatitis\n* Personal history of first-degree relative history of medullary thyroid carcinoma and\u002For multiple endocrine neoplasia type 2\n* Known hypersensitivity to GLP1 agonists\n* Other participants from the same household who are participating in this trial\n* Any disorder, unwillingness, or inability, which in the investigator's opinion might jeopardize the participant's safety or compliance with the protocol","ALL","12 Years",{"count":58,"type":23},1020,"INTERVENTIONAL",[61],"PHASE4","The rapid emergence of new and highly effective obesity medications has turned the field of pediatric weight management on its head. Adolescents living with obesity, their caregivers, healthcare providers, healthcare systems, policymakers, and payors are now wondering what role health behavior and lifestyle treatment (HBLT) has in terms of body mass index (BMI) reduction, improvements in quality of life and cardiometabolic health, and mitigating nutritional concerns when medications are used. Is intensive HBLT needed or could low intensity HBLT be an equally effective alternative; and if so, for whom? Our proposed project will answer these important questions that arise daily in the clinical setting and will generate critical new insights to guide decision-making for teens with obesity and the stakeholders who care deeply about them.",[29],"NOT_YET_RECRUITING","2026-06-12",{"date":67,"type":38},"2026-06-16",{"date":69,"type":23},"2026-10-01",{"date":71,"type":23},"2032-01-31",{"name":73,"class":45},"University of Minnesota",{"id":75,"slug":76,"hasResults":12,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":17,"sex":55,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":86,"conditions":87,"keywords":88,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":46},"100444880","resilience-to-the-effects-of-advertising-in-children-100444880","NCT05073185","Resilience to the Effects of Advertising in Children","Characterizing Resilience to Food-cue Induced Overeating in Children","REACH","Child Inclusion Criteria:\n\n1. In order to be enrolled, children must be of good health based on parental self-report.\n2. Have no learning disabilities (e.g., ADHD).\n3. Have no allergies to the foods or ingredients used in the study.\n4. Not be claustrophobic.\n5. Not be taking any medications known to influence body weight, taste, food intake, behavior, or blood flow.\n6. Be 7-9 years-old at enrollment.\n7. The child must speak English.\n\nParent Inclusion Criteria:\n\n1. The parent who has the most knowledge of the child's eating behavior, media access, sleep and behavior must be available to attend the visits with their child. This would be decided among the parents.\n2. The biological mother must have a body mass index either between 18.5 - 25 kg\u002Fm2 (low-risk group) or greater than or equal to 30 kg\u002Fm2 (high-risk group). One parent can report on both parents' BW and height.\n\nExclusion Criteria:\n\nChildren would be excluded if:\n\n1. They are not within the age requirements (\\\u003C than 7 years old or \\> than 9 years-old at baseline).\n2. If they are taking cold or allergy medication, or other medications known to influence cognitive function, taste, appetite, or blood flow.\n3. If they don't speak English.\n4. If they are colorblind\n5. If they report being claustrophobic.\n6. if they have a learning disability, ADD\u002FADHD, language delays, autism or other neurological or psychological conditions.\n7. if they have a pre-existing medical condition such as type I or type II diabetes, rheumatoid arthritis, Cushing's syndrome, Down's syndrome, food allergies, severe lactose intolerance, Prader-Willi syndrome, HIV, cancer, renal failure, or cerebral palsy.\n8. if they are allergic to foods or ingredients used in the study.\n9. if they have tattoos, permanent makeup, dental ware, pacemakers, or metal implants that would preclude safe completion of the MRI.\n10. if the child has had an X-ray in the month prior to Visits 1 and 6. If so, they will be scheduled at a later date.\n\nParent Exclusion Criteria:\n\n1. if the biological mother has a body mass index \\\u003C 18.5 kg\u002Fm2\n2. if the mother is between 25-30 kg\u002Fm2.\n3. if the parent is unable to attend the study visits\n4. if the family reports plans to move away from the area in the next year.","7 Years","9 Years",{"count":85,"type":23},200,"Strong empirical evidence shows food marketing promotes excess energy intake and obesity. Yet, not all children are susceptible to its effects and this variability is poorly understood. Identifying sources of this variability is a public health priority not only because it may elucidate characteristics of children who are most susceptible, but also because it may highlight novel sources of resiliency to overconsumption. The proposed research will use state-of-the art, data-driven approaches to identify neural, cognitive and behavioral phenotypes associated with resiliency to food-cue (i.e. food advertisement) induced overeating and determine whether these phenotypes protect children from weight gain during the critical pre-adolescent period.",[29],[89,90,91,92,93,94],"Obesity","food-cue reactivity","functional magnetic resonance imaging","eating behaviors","food marketing","food advertisement","2026-05-18",{"date":97,"type":38},"2026-05-20",{"date":99,"type":38},"2022-05-01",{"date":101,"type":23},"2026-12",{"name":103,"class":45},"Penn State University",{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":55,"minAge":56,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":46},"100568534","beta-cell---liver-interactions-in-situations-of-modified-beta-cell-function-100568534","NCT06682481","Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function","Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function: From Mice to Children","Inclusion Criteria:\n\n* Children aged 12 to 16 years\n* Obesity. Defined as a body-mass index above the 97th percentile.\n* Ability to give informed consent as documented by signature\n\nExclusion Criteria:\n\n* Patients with diabetes mellitus and positive autoantibodies against islets, insulin, islet antigen 2, glutamic acid decarboxylase or Zinc transporter 8.\n* Patients with known liver disease (other than NAFLD)\n* Patients treated with an oral antidiabetic drug, glucagon-like peptide-1 analogues or insulin at the time of or less than 2 weeks prior to inclusion.\n* Patients treated with a drug known to affect liver function","16 Years",{"count":113,"type":23},50,"The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.",[29,116],"Type 2 Diabetes Mellitus in Obese","2026-05-14",{"date":95,"type":38},{"date":120,"type":38},"2024-11-22",{"date":122,"type":23},"2028-12-31",{"name":124,"class":45},"Philippe Klee, MD-PhD",{"id":126,"slug":127,"hasResults":12,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":12,"sex":55,"minAge":4,"maxAge":4,"enrollmentInfo":132,"targetDuration":134,"studyType":25,"phases":4,"briefSummary":135,"conditions":136,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":46},"100496725","genetic-disorders-of-obesity-program-database-100496725","NCT05747976","Genetic Disorders of Obesity Program Database","GDOP","Inclusion Criteria:\n\n* For individuals 2 years and older, BMI \\> 97 percentile\n* For individuals \\\u003C 2 years old, weight-to-length ratio \\> 95th percentile\n\nExclusion Criteria:\n\n* No other exclusion criteria",{"count":133,"type":23},500,"1 Year","This study collects data on children with severe, early-onset obesity.",[29,137],"Genetic Disease","2026-05-07",{"date":140,"type":38},"2026-05-12",{"date":142,"type":38},"2020-08-30",{"date":144,"type":23},"2030-12-31",{"name":146,"class":45},"Baylor College of Medicine",{"id":148,"slug":149,"hasResults":12,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":12,"sex":18,"minAge":154,"maxAge":56,"enrollmentInfo":155,"targetDuration":4,"studyType":59,"phases":157,"briefSummary":159,"conditions":160,"keywords":161,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":46},"100640095","effects-of-blowing-balloon-therapy-function-dyspnea-and-quality-of-life-in-obese-children-100640095","NCT07576478","Effects of Blowing Balloon Therapy FUNCTION, DYSPNEA AND QUALITY OF LIFE IN OBESE CHILDREN","Effects of Blowing Balloon Therapy on Pulmonary Function, Dyspnea and Quality of Life in Obese Children","Inclusion Criteria:\n\n* Obese children having 30 or greater than 30 BMI\n\n  * Age: 6 to 12 years .\n  * Children with atleast light to moderate intensity dyspnea (RPE 8-14)\n\nExclusion Criteria:\n\n* Recent asthma exacerbation or respiratory infection in the past 4 weeks.\n\n  * Other chronic respiratory (e.g. cystic fibrosis) or cardiac diseases.\n  * Musculoskeletal, neurological, or other conditions that contraindicate exercise.\n  * Non-ambulatory status or inability to perform the exercise protocol","6 Years",{"count":156,"type":23},38,[158],"NA","The respiratory system is divided into upper and lower tracts and functions through gaseous exchange, ventilation, and perfusion, with normal breathing depending on lung compliance, airway resistance, and muscular strength. Pulmonary function is assessed using spirometry, particularly Forced Vital Capacity (FVC) and Forced Expiratory Volume in 1 second (FEV₁), which are often reduced in obese children due to excess adipose tissue restricting chest wall expansion and diaphragmatic movement, contributing to dyspnea. This randomized controlled trial will be conducted over 10 months in Lahore at selected hospitals and schools, involving 38 obese children (BMI ≥30), aged 6-12 years with mild to moderate dyspnea (RPE 8-14), who will be randomly assigned to either an experimental group receiving blowing balloon therapy or a control group performing splint running (n=19 each). Participants will be screened using the Borg RPE Scale, and data will be analyzed using SPSS version 20.",[29],[162],"Blowing Balloon Therapy (BBT), Pulmonary Function, Dyspnea,","2026-05-04",{"date":165,"type":38},"2026-05-08",{"date":167,"type":38},"2026-04-13",{"date":169,"type":23},"2026-08-15",{"name":171,"class":45},"Riphah International University",{"id":173,"slug":174,"hasResults":12,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":4,"eligibilityCriteria":178,"healthyVolunteers":12,"sex":55,"minAge":179,"maxAge":180,"enrollmentInfo":181,"targetDuration":4,"studyType":59,"phases":183,"briefSummary":184,"conditions":185,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":194},"100546712","a-primary-care-based-intervention-to-prevent-childhood-obesity-among-low-income-latino-children-100546712","NCT06398509","A Primary Care Based Intervention to Prevent Childhood Obesity Among Low-income Latino Children","Futuros Fuertes 2.0 A Primary Care Based Intervention to Prevent Obesity Among Low-income Latino Children","Inclusion Criteria:\n\n* Parent\u002Fcaregiver self identifies as Latino\n* Parent\u002Fcaregiver speaks Spanish or English\n* Parent\u002Fcaregiver intends to receive primary care for infant at participating clinic\n* Infant gestational age of 37 weeks or greater\n* Infant birthweight of 2600 grams or greater\n* For multiples (twins, triplets), one sibling will be chosen at random to participate\n\nExclusion Criteria:\n\n-Infant has a serious medical condition that affects feeding or growth","7 Days","2 Months",{"count":182,"type":23},576,[158],"The goal of this study is to evaluate the impact of a primary care based intervention to promote optimal feeding, screen time and sleep practices among low-income Latino infants and toddlers. Infants and caregivers will receive brief health education and coaching sessions from health educators at primary care visits in the first two years of life as well as two text messages per week with health information and tips. Half of the participants will receive the Futuros Fuertes 2.0 intervention that includes health coaching and education on infant feeding, screen time and sleep (intervention group). The other half will receive health coaching and education on safety, home management of childhood illnesses, and promotion of language development (control group). We will look at the impact of the Futuros Fuertes 2.0 intervention on child BMI and various health behaviors.",[29],{"date":187,"type":38},"2026-04-16",{"date":189,"type":38},"2024-05-13",{"date":191,"type":23},"2029-06-01",{"name":193,"class":45},"University of California, San Francisco",2,{"id":196,"slug":197,"hasResults":12,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":17,"sex":55,"minAge":202,"maxAge":19,"enrollmentInfo":203,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":205,"conditions":206,"keywords":209,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":224},"100514772","national-blood-pressure-screening-in-children-to-improve-paediatric-healthcare-in-south-africa-100514772","NCT05982847","National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa","National Blood Pressure Screening in Children to Optimise Clinical Management of Paediatric Hypertension in South Africa","Inclusion Criteria:\n\n* All children between ages 5-\\\u003C18 years\n* All children with voluntary assent\u002Fconsent and parent's permission\n\nExclusion Criteria:\n\n* circumstances interfere with the participant's ability to give informed consent (diminished understanding or comprehension, or any language barriers that may pose potential risk in participation under false expectations)\n* randomly selected children who choose not to participate (lack of assent\u002Fconsent), even if parent's permission was received,\n* conditions that interfere with a patient's ability to follow study guidelines, e.g., the use of drugs, alcohol or tobacco products\n* ages \\>18 years or under 5 years\n* Children will be excluded from the analysis for the determination of normative reference values for blood pressure and anthropometry if taking certain concomitant medication(s) that may affect their blood pressure, or any underlying disease e.g., chronic kidney disease, chronic heart disease etc. that may raise blood pressure.","5 Years",{"count":204,"type":23},22464,"The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.",[207,208,29],"Hypertension","Obesity, Adolescent",[210,211,212,213,214],"Adiposity","Blood Pressure","Cardiovascular Diseases","Health Knowledge, Attitudes, Practice","Lifestyle Factors","2026-04-06",{"date":217,"type":38},"2026-04-07",{"date":219,"type":38},"2024-04-01",{"date":221,"type":23},"2028-11-30",{"name":223,"class":45},"North-West University, South Africa",11,{"id":226,"slug":227,"hasResults":12,"nctId":228,"briefTitle":229,"officialTitle":229,"acronym":4,"eligibilityCriteria":230,"healthyVolunteers":12,"sex":55,"minAge":231,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":59,"phases":233,"briefSummary":234,"conditions":235,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":46},"100551777","whole-foods-for-teens-a-pilot-dietary-intervention-to-reduce-body-adiposity-in-adolescents-with-obesity-100551777","NCT06464497","Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity","Inclusion Criteria:\n\nFor this study, eligible adolescents will be those that:\n\n1. 10-18 years of age at time of initial screening;\n2. living at home full-time with the enrolled parent or caregiver (≥80% in primary residence);\n3. obesity defined as a body mass index (BMI) greater than or equal to 95th percentile for age and gender based on standardized CDC growth curves;\n4. reside within greater Middle Tennessee area and has enrolled parent\u002Fcaregiver willing to drive to Vanderbilt University and Vanderbilt University Medical Center for study visits;\n5. are without medical conditions that would limit participation in a diet-related study (e.g., tube feeding, dysphagia, severe food allergy to 3 or more food groups causing anaphylaxis);\n6. are willing and able to participate in an 8-week diet study that encourages preparing and eating healthy foods and snacks for 8 weeks with parental or caregiver support;\n7. have parental or caregiver commitment to participate in the research study;\n\nFor this study, eligible adult parents or caregivers will be those that:\n\n1. adult parent or primary legal caregiver (greater than or equal to 25 years of age) of an enrolled adolescent;\n2. live with the adolescent full-time (≥80% in primary residence);\n3. have 1 or more metabolic risk factor(s) and\u002For metabolic condition(s) (e.g., overweight\u002Fobesity, hypertension, hypercholesterolemia or dyslipidemia, hyperglycemia \\[elevated fasting blood glucose ≥100 mg\u002FdL\\] and\u002For prediabetes, history of gestational diabetes, polycystic ovarian syndrome, type 2 diabetes, non-alcoholic fatty liver disease);\n4. reside within greater Middle Tennessee area and are willing to drive to Vanderbilt University and Vanderbilt University Medical Center for study visits;\n5. are without medical conditions that would limit participation in a diet-related study (e.g., tube feeding, dysphagia, severe food allergy to 3 or more food groups);\n6. are able to participate in a study program that encourages preparing and eating healthy foods and snacks for 8 weeks with most preparation\u002Fcooking of meals\u002Fsnacks at home;\n\nExclusion Criteria:\n\nAdolescent exclusion criteria include:\n\n1. Outside of the specified age range;\n2. not living in the home of the enrolled parent or caregiver full time (≥80% in primary residence);\n3. BMI less than 95th percentile for age and gender;\n4. pregnant or lactating;\n5. no eligible enrolled parent or caregiver or lack of parental\u002Fcaregiver commitment to participate in study;\n6. food allergy to 3 or more food groups; dietary restrictions or medical condition that prohibits participation in a diet study;\n7. use of medications that cause weight loss or diabetes medications;\n8. active participation in a weight loss or intense lifestyle modification program;\n9. limited English-language proficiency;\n10. participants unwilling or unable to give informed consent, accept random assignment, attend dietary counseling sessions, adhere to treatment prescription, or complete study measures;\n11. adolescents who display dissenting behaviors during baseline data collection;\n12. adolescents who do not otherwise meet the eligibility criteria listed in sections above as determined by pre-screen;\n\nAdult Parent or Caregiver exclusion criteria include:\n\n1. not parent\u002F or legal caregiver;\n2. not living in a household full-time with enrolled adolescent (less than 80% time spent away from primary residence);\n3. lack of metabolic condition(s) per inclusion criteria;\n4. special dietary restrictions, food allergies, or medical conditions that prohibit participation in a diet-related study;\n5. limited English-language proficiency;\n6. participants unwilling or unable to give informed consent, accept random assignment, attend dietary counseling sessions, adhere to treatment prescription, or complete study measures;\n7. parent or caregivers who do not otherwise meet the eligibility criteria listed in sections above as determined by pre-screen;","10 Years",{"count":22,"type":23},[158],"This study will address the following aims:\n\nAim 1: Conduct an 8-week pilot RCT to examine the effects of a whole foods diet intervention on body adiposity in adolescents with obesity.\n\nAim 1a (Primary): Evaluate intervention effectiveness on total fat mass following the 8-week intervention.\n\nHypothesis 1a: Adolescents randomized to the whole foods intervention will have lower total fat mass (kg) at the 8-week follow-up than those in the control group.\n\nAim 1b: Evaluate intervention effectiveness on anthropometric changes following the 8-week intervention.\n\nHypothesis 1b: Adolescents randomized to the whole foods intervention will have lower weight, BMI-z scores and\u002For waist circumference at the 8-week follow-up than those in the control group.\n\nSecondary Aims:\n\nAim 2: Conduct an 8-week pilot RCT to examine the effects of a whole foods diet intervention on diet quality in adolescent and parent pairs during the study period.\n\nHypothesis 2: Adolescents and parents randomized to the whole foods intervention will have higher diet quality scores at the 8-week follow-up than those in the control group.\n\nAim 3: Conduct post-intervention family focus groups to identify how individual\u002Ffamily needs and preferences and social determinants of health (SDOH) may be perceived barriers and\u002For facilitators of diet adherence to a whole foods diet pattern.",[29,236,237],"Diet, Healthy","Body Weight Changes","2026-03-18",{"date":240,"type":38},"2026-03-23",{"date":242,"type":38},"2025-03-24",{"date":244,"type":23},"2027-04-30",{"name":246,"class":45},"Vanderbilt University",{"id":248,"slug":249,"hasResults":12,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":4,"eligibilityCriteria":253,"healthyVolunteers":12,"sex":55,"minAge":154,"maxAge":19,"enrollmentInfo":254,"targetDuration":4,"studyType":59,"phases":256,"briefSummary":257,"conditions":258,"keywords":259,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":263,"lastUpdatePostDateStruct":264,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":270,"locationsCount":46},"100504374","effects-of-auricular-acupressure-versus-intermittent-dietary-restriction-in-children-with-gastric-heat-and-dampness-obstruction-100504374","NCT05847478","Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction","Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Have at least one of the following cardiometabolic risk factors: overweight or obesity, prediabetes, dyslipidemia or elevated blood pressure.\n* Traditional Chinese medical syndrome type is gastric heat and dampness obstruction syndrome.\n\nExclusion Criteria:\n\n* Diagnosis of obesity associated with genetic or endocrine diseases, including hypercortisolism, polycystic ovary syndrome, primary hypothyroidism and hypothalamic obesity.\n* Participating in other clinical trials or have participated in other clinical trials in recent 3 months.\n* Diagnosis of organic diseases, including heart, liver, kidney and brain or infectious diseases and mental diseases.",{"count":255,"type":23},240,[158],"This is a three-month randomized controlled trial to investigate the effects of auricular acupressure versus Intermittent carbohydrate restriction on cardiometabolic risk in obese children with gastric heat and dampness obstruction.",[29],[260,261,262],"Auricular acupressure","Intermittent dietary restriction","Gastric Heat and Dampness Obstruction","2026-03-17",{"date":265,"type":38},"2026-03-19",{"date":267,"type":38},"2023-06-07",{"date":269,"type":23},"2026-12-31",{"name":271,"class":45},"Children's Hospital of Fudan University",{"id":273,"slug":274,"hasResults":12,"nctId":275,"briefTitle":276,"officialTitle":277,"acronym":278,"eligibilityCriteria":279,"healthyVolunteers":12,"sex":55,"minAge":154,"maxAge":280,"enrollmentInfo":281,"targetDuration":4,"studyType":59,"phases":282,"briefSummary":283,"conditions":284,"keywords":287,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":301,"locationsCount":46},"100578381","brief-behavioral-sleep-intervention-for-obesity-prevention-in-primary-care-100578381","NCT06810557","Brief Behavioral Sleep Intervention for Obesity Prevention in Primary Care","Feasibility and Preliminary Efficacy of a Brief Behavioral Sleep Intervention for Excessive Weight Gain Prevention in Primary Care","Rx SLEEP","Inclusion Criteria:\n\n* Patient at Temple Pediatrics\n* Child age 6-11 years\n* Child time in bed of less than 9 hours per night on most days per week\n* Body Mass Index (BMI) for age and biological sex great than the 10th percentile but less than the 95th percentile\n* Understanding of and ability to complete the protocol\n* Parent age at least 18 years and primary caregiver\n* Willingness to be randomized to either condition\n\nExclusion Criteria:\n\n* Diagnosed sleep disorder\n* Medication use or diagnosis of medical or psychiatric condition that may impact sleep or weight status\n* Current or planned treatment for weight control","11 Years",{"count":113,"type":23},[158],"The goal of this study is to compare two different approaches to help families with children 6-11 years enhance nighttime sleep: 1) working one-on-one with a nurse to learn effective behavioral strategies to try to improve children's sleep or 2) receiving education on a good night's sleep and its benefits. Participating families will meet with a nurse 6 times or receive 6 educational handouts. Participating families will also complete three assessments (start of the study, 2 months and 6 months) during which study questionnaires will be completed, participating children will wear devices that assess sleep and physical activity, participating families will report on what the child ate on two separate days and will be measured for height and weight.",[29,285,286],"Short Sleep","Obesity Prevention",[288,289,290,291,292,293],"sleep","behavioral intervention","primary care","obesity prevention","child","pediatric","2026-02-10",{"date":296,"type":38},"2026-02-12",{"date":298,"type":38},"2025-05-15",{"date":300,"type":23},"2027-03-31",{"name":302,"class":45},"Temple University",{"id":304,"slug":305,"hasResults":12,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":309,"eligibilityCriteria":310,"healthyVolunteers":17,"sex":55,"minAge":56,"maxAge":311,"enrollmentInfo":312,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":314,"conditions":315,"keywords":325,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":194},"100460586","brain-health-in-youth-with-normal-weight-overweight-and-obesity-at-risk-for-type-2-diabetes-t2d-100460586","NCT05277558","Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)","Brain Health Across the Metabolic Continuum in Youth at Risk for Type 2 Diabetes (T2D)","Metabrain","Inclusion Criteria:\n\n* 12-17 yrs. old at visit 1, 12-19 yrs. old at visit 2, Tanner II or above (determined through an exam by a pediatric endocrinologist or certified nurse practitioner trained in pediatric endocrinology), otherwise healthy except for obesity, \\\u003C450 lbs. (due to MRI scanner limits), able and willing to lie flat within the MRI scanner and do cognitive testing, fluent in English.\n\nExclusion Criteria:\n\n* Syndromic obesity, history of bariatric surgery, insulin treatment (metformin allowed if \\\u003C 6 months) for T2D, contraindications for MRI (metal, claustrophobia), braces, pregnant (pregnancy test will be done on post-menarchal girls) or breastfeeding, inability to participate in cognitive testing due to sensory or language issues, intellectual disability, special education, pharmacologic treatment for Attention Deficit Hyperactivity Disorder (ADHD), prematurity (\\\u003C36 weeks gestation), complications at birth, neurologic co-morbidities (e.g., seizures, stroke, head injury with \\>10 min loss of consciousness), significant psychiatric disorders (e.g., schizophrenia, bipolar disorder, current major depression), taking psychoactive medications (e.g., antipsychotics) that would interfere with testing or reporting illegal drug use. Self-reported smoking and alcohol use and length of time with obesity will be assessed by history (although these measures may not be fully reliable).","17 Years",{"count":313,"type":23},117,"Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function among groups, over time, and how these effects differ from normal neurodevelopment.",[316,116,317,318,319,29,320,321,322,323,324],"Type2 Diabetes","Dysglycemia","Microvascular Complications","Brain Structure","Diabetes in Adolescence","Inflammation","Insulin Resistance","Overweight, Childhood","Cognitive Decline",[326],"Brain, Health, Youth, Type 2 Diabetes Mellitus, overweight, obesity","2025-12-16",{"date":329,"type":38},"2025-12-18",{"date":331,"type":38},"2022-05-24",{"date":333,"type":23},"2027-10-31",{"name":335,"class":45},"Washington University School of Medicine",{"id":337,"slug":338,"hasResults":12,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":342,"eligibilityCriteria":343,"healthyVolunteers":12,"sex":55,"minAge":344,"maxAge":311,"enrollmentInfo":345,"targetDuration":4,"studyType":59,"phases":346,"briefSummary":347,"conditions":348,"keywords":350,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":46},"100549344","comparative-effectiveness-of-a-healthy-lifestyle-and-asthma-management-program-in-person-vs-online-100549344","NCT06432790","Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline","Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline (CHAMPION)","CHAMPION","Caregiver-proxies will be 18 years old or older, English or Spanish speaking, and a primary caregiver of a child meeting the following criteria:\n\nInclusion criteria\n\n* Age 4-17.9 years at time of screening\n* BMI ≥ 85th percentile\n* Asthma or reactive airway disease diagnosis, per child's Electronic Health Record (EHR) documentation and caregiver report\n\nExclusion criteria\n\n* Diagnosis of anorexia nervosa, per child's EHR or caregiver report\n* Pregnant, per child's EHR\n* Plan to change pediatricians in the next year, per caregiver report\n* Opted out of research, per child's EHR\n* Sibling currently enrolled in the research trial, per enrollment log or caregiver report","4 Years",{"count":133,"type":23},[158],"The goal of this study is to evaluate the effectiveness of CHAMPION (\"Comparative-effectiveness of a Healthy lifestyle and Asthma Management Program, In-person vs ONline\"), a primary care-based intervention to address childhood obesity and asthma, and test the effectiveness of a telehealth-only version of the program. Intensive Health Behavior and Lifestyle Treatment (IHBLT), when delivered via telehealth vs. in-person among children with overweight or obesity and persistent asthma.",[323,29,349],"Asthma in Children",[351],"telehealth","2025-11-14",{"date":354,"type":38},"2025-11-18",{"date":356,"type":38},"2024-07-17",{"date":358,"type":23},"2028-07-31",{"name":360,"class":45},"Massachusetts General Hospital",{"id":362,"slug":363,"hasResults":12,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":4,"eligibilityCriteria":367,"healthyVolunteers":12,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":368,"targetDuration":4,"studyType":59,"phases":370,"briefSummary":372,"conditions":373,"keywords":374,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":377,"startDateStruct":379,"completionDateStruct":381,"leadSponsor":383,"locationsCount":46},"100406917","phase-3-fiber-and-metformin-combination-therapy-in-adolescents-with-severe-obesity-and-insulin-resistance-100406917","NCT04578652","Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance","Fiber Supplementation and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance: Interactions With the Gut Microbiome.","Inclusion Criteria:\n\n1. Age 12-18 years\n2. BMI percentile \\> 95% for age\u002Fsex;\n3. Total weight fluctuation over past 6 months \\\u003C 10%;\n4. HOMA-IR \\> 3.16;\n5. FH of T2DM (first or second-degree relative).\n\nExclusion Criteria:\n\n1. Current use of insulin or diagnosis of T2DM;\n2. Systolic or diastolic blood pressure (BP) \\> 99th percentile for age and sex;\n3. Acute infectious or inflammatory condition over the preceding 1 month; hospitalization \\> 48 hrs;\n4. History of chronic disease such as inflammatory bowel disease, chronic severe liver or kidney disease or neurologic disorders;\n5. Active malignancy;\n6. Concomitant use of medication\u002Finvestigational drug known to affect body weight in the past year;\n7. Antibiotic use in past 60 days; probiotic and\u002For prebiotic supplements use in the past 30 days; use of lipid-lowering and anti-inflammatory medication.",{"count":369,"type":23},90,[371],"PHASE3","This is a 12-month, single center, three-arm parallel design, double-blind, randomized clinical trial, to compare the effects of supplemental dietary fiber and metformin (MET) alone and in combination over 12 months on glucose metabolism (insulin resistance \\[IR\\]), inflammation and BMI in adolescents with obesity and IR, and to assess the relationship between therapeutic intervention(s) and changes in gut microbiome composition and function.\n\nSince MET and FIBER have been shown to reduce weight and increase insulin sensitivity through distinct but overlapping mechanisms of action, our central hypothesis is that the combination of FIBER + MET will have a synergistic effect and be more effective than FIBER or MET alone in improving metabolic function (IR) and reducing BMI and inflammation in adolescents with obesity, IR and family history (FM) of T2DM.\n\n.",[29,322],[375,376],"Dietary fiber","Metformin",{"date":378,"type":38},"2025-11-17",{"date":380,"type":38},"2021-10-22",{"date":382,"type":23},"2026-09",{"name":384,"class":45},"University of Alberta",{"id":386,"slug":387,"hasResults":12,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":391,"eligibilityCriteria":392,"healthyVolunteers":17,"sex":55,"minAge":202,"maxAge":82,"enrollmentInfo":393,"targetDuration":4,"studyType":59,"phases":395,"briefSummary":396,"conditions":397,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":398,"lastUpdatePostDateStruct":399,"startDateStruct":401,"completionDateStruct":403,"leadSponsor":404,"locationsCount":46},"100499477","food-genetics-behavior-study-100499477","NCT05783765","Food Genetics Behavior Study","Role of Energy Balance Behaviors in Modifying Biobehavioral Risk Factors for Childhood Obesity","FOODIE","Inclusion Criteria:\n\n* Healthy children\n* Children ages 5-7 years\n* Children with BMI equal to or greater 5th percentile\n* Mother must be children's biological mother and primary caregiver\n* Mother must be able to read and understand English\n\nExclusion Criteria:\n\n* Children with serious medical conditions or medication use known to affect food intake, body weight, physical activity, or sleep\n* Children with developmental and\u002For psychiatric conditions that may impact study compliance\n* Children with food allergies related to study foods or lactose intolerance\n* Children with low preference for study foods",{"count":394,"type":23},242,[158],"A genetic risk for obesity does not always translate to the development of obesity among children, which points to the presence of risk-modifying factors that likely relate to energy balance behaviors as key behavioral drivers. Using an integrated approach to comprehensively examine the interplay between genotype and phenotype, this study will systematically assess the extent to which energy balance behaviors, alone or in combination, in conjunction with family-level influences can modify behavioral and genetic predispositions to childhood obesity in a high-risk sample of predominantly minority children from low-resource backgrounds. Identifying protective factors that may mitigate the impact of obesity risk on weight and adiposity outcomes is critical for moving the prevention of childhood obesity into a new direction.",[29],"2025-10-29",{"date":400,"type":38},"2025-10-30",{"date":402,"type":38},"2023-07-26",{"date":333,"type":23},{"name":405,"class":45},"University of Pennsylvania",{"id":407,"slug":408,"hasResults":12,"nctId":409,"briefTitle":410,"officialTitle":411,"acronym":4,"eligibilityCriteria":412,"healthyVolunteers":17,"sex":55,"minAge":413,"maxAge":202,"enrollmentInfo":414,"targetDuration":4,"studyType":59,"phases":416,"briefSummary":418,"conditions":419,"keywords":424,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":431,"lastUpdatePostDateStruct":432,"startDateStruct":434,"completionDateStruct":436,"leadSponsor":437,"locationsCount":46},"100562000","phase-2-food-body-mind-intervention-16-weeks-100562000","NCT06597474","Food-Body-Mind Intervention (16 Weeks)","Food-Body-Mind Intervention: Promote Whole Child Health","Inclusion Criteria:\n\n1. Parental consent and child (if the child is 5 years) verbal assent received\n2. Children are 3-5 years old attending a Head Start program and caregivers are the primary adult caregivers for the children\n3. Caregivers are willing to use Facebook or the private program website for participation\n4. Participants have at least weekly internet access using a smartphone, a tablet, or a computer\n\nExclusion Criteria:\n\n1. preschoolers who have a motor disability or impairment (e.g., cerebral palsy, spinal cord injury, lost or damaged limb, motor skills disorder, muscular dystrophy, spina bifida) preventing them from participating in any physical activity;\n2. preschoolers who have a diagnosed medical condition (e.g., phenylketonuria, pediatric malabsorption syndrome, pollen food allergy syndrome) requiring a restrict diet and precluding them from any dietary changes particularly fruit\u002Fvegetable intake; and\n3. preschoolers who have diagnosed disorders (e.g., autism spectrum disorder level 3) causing severe difficulty (e.g., nonverbal, cannot initiate social interaction) with communication and interaction with other people.\n\nThere will be no exclusion criterion for primary adult caregivers, as the primary focus is preschoolers and caregivers serve as a support role.","3 Years",{"count":415,"type":23},800,[417,371],"PHASE2","This novel, timely, and theory-driven Food-Body-Mind intervention addresses the national emergency of mental health crises in early childhood. By targeting Head Start racially\u002Fethnically diverse preschoolers from low-income backgrounds in both urban and rural areas, this intervention is expected to contribute toward reducing health disparities and promoting health equity, a major priority of the NIH and Healthy People 2030. If effective, it can be scalable to Head Start programs across urban and rural settings nationally with long-term sustainability benefits.",[420,421,422,423,29],"Mental Health Wellness","Emotional Problem","Behavioral Problem of Child","Social Skills",[425,426,427,428,429,430],"Mindfulness","Mindful eating","Yoga","Deep breathing","Family","Prevention","2025-09-22",{"date":433,"type":38},"2025-09-26",{"date":435,"type":38},"2024-08-14",{"date":358,"type":23},{"name":438,"class":45},"Michigan State University",{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":17,"sex":55,"minAge":82,"maxAge":4,"enrollmentInfo":446,"targetDuration":448,"studyType":25,"phases":4,"briefSummary":449,"conditions":450,"keywords":458,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":463,"lastUpdatePostDateStruct":464,"startDateStruct":466,"completionDateStruct":468,"leadSponsor":470,"locationsCount":46},"100287699","blood-collection-biorepository-for-liver-disease-research-100287699","NCT03025074","Blood Collection Biorepository for Liver Disease Research","Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases","Inclusion Criteria:\n\n* This protocol is to establish a biobank of blood samples from individuals with or without liver diseases including viral hepatitis, liver cancer, NASH, and negative control samples.\n* Children and teenagers will be special populations considered in this protocol.\n\nExclusion Criteria:\n\n* Vulnerable populations such as adults unable to consent, infants, pregnant women or prisoners will not be considered for this research study.",{"count":447,"type":23},1000,"1 Day","The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are studying the effects that fatty liver and viral diseases have on the liver.",[451,452,453,454,455,456,29,457],"Non-Alcoholic Steatohepatitis(NASH)","Hepatitis C","Hepatitis B","Fibrosis","Cirrhosis","Fatty Liver","Bariatric Surgery Candidate",[459,89,460,461,462],"Liver Disease","Hepatitis","HIV","Hepatology","2025-08-20",{"date":465,"type":38},"2025-08-27",{"date":467,"type":4},"2013-07",{"date":469,"type":23},"2099-12",{"name":471,"class":45},"State University of New York at Buffalo",{"id":473,"slug":474,"hasResults":12,"nctId":475,"briefTitle":476,"officialTitle":477,"acronym":478,"eligibilityCriteria":479,"healthyVolunteers":12,"sex":55,"minAge":202,"maxAge":19,"enrollmentInfo":480,"targetDuration":4,"studyType":59,"phases":482,"briefSummary":483,"conditions":484,"keywords":485,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":490,"lastUpdatePostDateStruct":491,"startDateStruct":493,"completionDateStruct":495,"leadSponsor":497,"locationsCount":499},"100325434","phase-3-monthly-boluses-versus-daily-doses-for-correcting-blood-vitamin-d-deficit-in-obese-children-and-adolescents-100325434","NCT03516968","Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents","Treatment of Vitamin D Deficit in Obese Children and Adolescents: an Open Label Randomized Controlled Study Comparing the Efficacy of Two Oral Supplementation Regimens: Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Level: OBEVIDOS","OBEVIDOS","Inclusion Criteria:\n\n* Aged between 5 to 18 year-old\n* Being obese (BMI \\>97th percentile, \\> IOTF 30, for age and gender using the WHO references)\n* Patients (parents) having given their informed consent\n* Patient having insurance from the national health system\n\nExclusion Criteria:\n\nChildren will be excluded from the study if:\n\n* Symptomatic vitamin D deficiency (tetany, muscular hypotonia, hypocalcaemic seizure)\n* Vitamin D supplementation in the 3 months preceding the inclusion visit (V1)\n* Signs of rickets at the X-ray (osteopenia and cortical thinning of the long bones, stress fractures, and metaphyseal widening and fraying)\n* Chronic disease such as granulomatous conditions, Williams syndrome, or hypothyroidism predisposing to hypocalcaemia or in case of hypercalcaemia (calcium \\> 2.65 mmol\u002FL), liver\u002Fkidney disease, malabsorption diseases;\n* Hypercalciuria (urinary Calcium\u002FCreatinine \\> 0.7 mmol\u002Fmmol), calcium nephrolithiasis, hypervitaminosis D (25-(OH)D \\> 250 nmol\u002FL); nephrocalcinosis;\n* Ongoing treatment with anticonvulsants\u002Fbarbiturates or steroids which increase the catabolism of 25(OH)D;\n* Ongoing treatment with thiazides diuretics which reduce urinary excretion of calcium;\n* Contraindications to the class of drugs under study, e.g. known hypersensitivity or allergy to class of drugs or the investigational product;\n* Pregnancy, breastfeeding;\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant;\n* Simultaneous enrolment to another study which could influence the results of the current study;\n* Patient under legal protection or deprived of liberty.",{"count":481,"type":23},68,[371],"Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries. Overweight and obese children and adolescents are likely to remain so into adulthood and to develop chronic diseases at a young age, such as diabetes and cardiovascular disease.\n\nObese patients, whether adults or children, are likely to have low serum vitamin D levels due to sequestration and\u002For volumetric dilution of this fat-soluble vitamin in adipose tissue. Studies have established a link between vitamin D deficiency or insufficiency and chronic diseases such as hypertension, type 2 diabetes and other metabolic problems.\n\nDetermining physiological 25(OH)D levels to ensure optimal phosphocalcic metabolism and bone mineralisation requires the use of functional markers: parathyroid hormone (PTH) levels, assessment of the intestinal calcium absorption fraction, assessment of bone mineral density and bone mineral content using absorptiometry.\n\nVitamin D deficiency leads to malabsorption of calcium and phosphate in the digestive tract, with concentrations, especially of calcium, tending to fall in plasma, resulting in hypersecretion of PTH, which mobilises bone calcium to maintain subnormal blood calcium levels.\n\nEach unit increase in BMI is associated with lower serum vitamin D concentrations: given these low concentrations in this population associated with the risk of developing pathologies, it is important to ensure adequate vitamin D supplementation.\n\nThe latest paediatric recommendations recommend, for children aged between 1 and 18 with vitamin D deficiency, a supplement of 2,000 IU\u002Fday for at least 6 weeks or a bolus of 50,000 IU once a week for at least 6 weeks.\n\nThere are different dosage regimens for the replacement of vitamin D deficiency depending on the country: there is a lack of data on the appropriate dosage and administration regimens for vitamin D supplementation in cases of deficiency, particularly in obese children and adolescents. A prospective, randomised clinical trial will make it possible to define the vitamin D supplementation regimen best suited to increasing serum vitamin D levels in these children and adolescents suffering from obesity.",[29],[89,486,487,488,489],"Vitamin D deficiency,","supplementation,","Child","Adolescent","2025-06-10",{"date":492,"type":38},"2025-06-13",{"date":494,"type":38},"2023-12-04",{"date":496,"type":23},"2027-03",{"name":498,"class":45},"Hospices Civils de Lyon",4,{"id":501,"slug":502,"hasResults":12,"nctId":503,"briefTitle":504,"officialTitle":505,"acronym":4,"eligibilityCriteria":506,"healthyVolunteers":17,"sex":55,"minAge":507,"maxAge":508,"enrollmentInfo":509,"targetDuration":4,"studyType":59,"phases":511,"briefSummary":513,"conditions":514,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":520,"lastUpdatePostDateStruct":521,"startDateStruct":523,"completionDateStruct":525,"leadSponsor":527,"locationsCount":46},"100308670","phase-1-vaginal-microbiome-seeding-and-health-outcomes-in-cesarean-delivered-neonates-100308670","NCT03298334","Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.","Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates: a Randomized Controlled Trial","Inclusion Criteria for Mother:\n\n* Scheduled for cesarean delivery at ≥ 37 weeks\n* Pregnant with single fetus, in good general health, age 18 years or older\n* Negative maternal testing for infections transmitted through vaginal and\u002For other body fluids performed as standard of care tests in early pregnancy\n* Negative testing for Group B strep at 35-37 weeks gestation\n* Vaginal pH ≤ 4.5 indicative of Lactobacillus-dominated vaginal microbiota\n* No maternal or fetal complications that may inhibit the ability to perform microbiome restoration per protocol\n* English or Spanish speaking\n* Negative maternal testing for Gonorrhea, Chlamydia, Hepatitis B, Hepatitis C, Syphilis, and HIV at 35 weeks gestation or later\n* Women aged 18-29 years must have a normal Pap test within 3 years\n* Women aged 30-65 years must have a normal Pap test and an HPV test (co-testing) within 5 years or FDA-approved primary hrHPV testing alone within 5 years or a normal Pap test alone within 3 years\n* Negative maternal testing for SARS-CoV-2 for the delivery admission performed as standard of care test at the Inova Health System.\n\nInclusion Criteria for Infant:\n\n* Infant condition after delivery requires no more than standard neonatal resuscitation\\* or is otherwise medically unable to receive the full VMT procedure\n\n\\[\\*\\] Standard neonatal resuscitation may include: tactile stimulation, bulb suction, oxygen without positive pressure, or drying\n\nExclusion Criteria for Mother:\n\n* Delivery at a hospital other than Inova Health System\n* Cesarean delivery scheduled for active infection that would have interfered with vaginal delivery such as genital herpetic lesions\n* Rupture of membranes prior to scheduled cesarean delivery\n* Bacterial vaginosis within 30 days of cesarean delivery\n* Symptomatic urinary tract infection within 30 days of cesarean delivery\n* Antibiotic therapy within 30 days of cesarean delivery (exclusive of medication use for prophylaxis at the time of surgery)\n* Symptoms on admission suggesting Chorioamnionitis, e.g. maternal fever, fundal tenderness\n* Symptoms on delivery admission of possible vaginal infection such as genital herpetic lesions\n* History of genital HSV\n* History positive testing for Group B strep infection\n* History of a child with a diagnosis of Group B strep sepsis\n* Pregnancy a result of donor egg or surrogacy\n* Preexisting history of Type I or Type II Diabetes\n* Maternal history of documented genital HPV infection, positive HPV testing or genital warts on physician examination\n* Positive maternal testing for SARS-CoV-2 within 30 days of delivery or symptoms on admission suggesting potential Covid-19 infection","0 Days","50 Years",{"count":510,"type":23},600,[512,417],"PHASE1","Neonates delivered by scheduled Cesarean Section will be randomized to receive vaginal seeding (exposing the infant to Mother's vaginal flora) or sham. Infants will be followed for three years to examine health outcomes including microbiome development, immune development, metabolic outcomes, and any adverse events.",[515,29,516,517,518,519],"Cesarean Delivery Affecting Newborn","Intestinal Microbiome","Microbiota","Host Microbial Interactions","Gastrointestinal Microbiome","2025-06-04",{"date":522,"type":38},"2025-06-08",{"date":524,"type":38},"2018-07-01",{"date":526,"type":23},"2029-04",{"name":528,"class":529},"National Institute of Allergy and Infectious Diseases (NIAID)","NIH",{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":535,"acronym":536,"eligibilityCriteria":537,"healthyVolunteers":17,"sex":55,"minAge":82,"maxAge":56,"enrollmentInfo":538,"targetDuration":4,"studyType":59,"phases":540,"briefSummary":541,"conditions":542,"keywords":543,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":194},"100532000","family-responsibility-education-support-and-health-for-food-responsiveness-100532000","NCT06207110","Family, Responsibility, Education, Support, and Health for Food Responsiveness","Addressing Appetitive Traits to Promote Weight Management in Children Who Overeat","FRESH-FR","Inclusion Criteria:\n\n1. Informed assent and parental consent\n2. A child with overweight or obesity (≥ 85th BMI%) aged 7-12 years of age\n3. Child high on FR - High FR will be measured by the Food Responsiveness Scale via the CEBQ, with scores at a 3.8 or higher constituting a child with high FR.\n4. A parent responsible for food preparation who is willing to participate and can read, speak and understand English at a minimum of a 5th grade level\n5. Family is willing to commit to attending all assessment and treatment sessions, agree to be randomized and participate in all aspects of potential treatments\n6. Child is on stable medication regimen for medications that can impact weight (3+ months)\n7. Child does not have medical conditions that limit ability to participate in physical activity for the duration of the study. Parent can participate in physical activity with their child or provide opportunities for the child to complete recommended physical activity\n\nExclusion Criteria:\n\n1. Acute child psychiatric disorder diagnoses (e.g., acute suicidality, recent hospitalization, psychosis, bulimia nervosa)\n2. Child diagnoses of a serious chronic physical disease (e.g., cystic fibrosis, type 1 diabetes) for which physician supervision of diet and exercise prescription may be warranted\n3. Child who is taking medication for weight loss\n4. Acute parent psychiatric disorder (e.g., acute suicidality; recent hospitalization; psychosis, bipolar disorder, borderline personality disorder, moderate or severe alcohol or substance use disorder)\n5. First degree relative or someone in the household with anorexia or bulimia nervosa.\n\nPotential participants with medical or psychological diagnosis that could make adherence with the study protocol difficult or dangerous will not be included.",{"count":539,"type":23},280,[158],"The objective of this proposed study is to compare Regulation of Cues (ROC), Family-Based Treatment (FBT), ROC+ nutrition education and reducing energy intake (ROC+) and a health education comparator (HE) for children with overweight or obesity who are high on food responsiveness (FR).",[29],[544,545,546,547],"Food Responsiveness","Satiety Responsiveness","Weight Loss","Overeating","2025-05-06",{"date":550,"type":38},"2025-05-11",{"date":552,"type":38},"2024-04-03",{"date":554,"type":23},"2029-01-01",{"name":556,"class":45},"University of California, San Diego",{"id":558,"slug":559,"hasResults":12,"nctId":560,"briefTitle":561,"officialTitle":561,"acronym":4,"eligibilityCriteria":562,"healthyVolunteers":17,"sex":55,"minAge":563,"maxAge":56,"enrollmentInfo":564,"targetDuration":4,"studyType":59,"phases":565,"briefSummary":566,"conditions":567,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":568,"lastUpdatePostDateStruct":569,"startDateStruct":571,"completionDateStruct":573,"leadSponsor":575,"locationsCount":194},"100511142","intervention-inc-an-interactive-family-centered-mhealth-tool-to-reduce-obesity-risk-in-urban-minority-preadolescents-100511142","NCT05935592","Intervention INC: An Interactive Family-centered mHealth Tool to Reduce Obesity Risk in Urban Minority Preadolescents","Inclusion Criteria (child):\n\n* self-identifies as Black\u002FAfrican-American and\u002For Latino\n* between ages 8 and 12 years (preadolescents) at time of scheduled baseline visits\n* reads and speaks in English\n* has a Body Mass Index percentile at or above 5% at baseline (categorized as healthy, overweight, or obese)\n* has regular internet access via a tablet device, smartphone, or computer\u002Flaptop\n* has regular access to a phone with texting capability\n* is comfortable reading\u002Fviewing material on electronic devices\n* is comfortable speaking with study staff about thoughts\u002Fexperiences while participating in study\n* has a legal parent\u002Fguardian willing to participate in study\n\nInclusion Criteria (parent):\n\n* legal parent\u002Fguardian of child willing to participate in study\n* reads and speaks in English or Spanish\n* primarily responsible for preparing\u002Fpurchasing food for child\n* has regular internet access via a tablet device, smartphone, or computer\u002Flaptop\n* has regular access to a phone with texting capability\n* comfortable reading\u002Fviewing material on electronic devices\n* able to attend in-person study visits and complete online questionnaires with their child over the full duration of study\n\nExclusion Criteria (child):\n\n* has allergies, food aversions, food disorders, or medications with side-effects that may impact participation in study\n* has a pacemaker or heart condition\n* in foster care","8 Years",{"count":85,"type":23},[158],"Using a two-group randomized study design, this study aims to evaluate the effectiveness of the adapted family-centered mHealth tool on child BMI z-score (primary outcome), child dietary behaviors, and parental feeding practices, from baseline to 12-month follow-up, among 200 child-parent dyads. It is hypothesized that children in the experimental group will demonstrate larger BMI-z score improvements between baseline and 12-month follow-up compared to children in the comparison group.",[29],"2025-04-07",{"date":570,"type":38},"2025-04-10",{"date":572,"type":38},"2025-02-27",{"date":574,"type":23},"2027-06",{"name":576,"class":45},"Tufts University",{"id":578,"slug":579,"hasResults":12,"nctId":580,"briefTitle":581,"officialTitle":582,"acronym":583,"eligibilityCriteria":584,"healthyVolunteers":12,"sex":55,"minAge":231,"maxAge":19,"enrollmentInfo":585,"targetDuration":4,"studyType":59,"phases":587,"briefSummary":588,"conditions":589,"keywords":591,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":597,"lastUpdatePostDateStruct":598,"startDateStruct":599,"completionDateStruct":601,"leadSponsor":602,"locationsCount":46},"100581212","efficacy-and-safety-of-vitamin-d-supplementation-in-pediatric-patients-with-obesity-100581212","NCT06847373","Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity","Efecto De La Suplementación De Vitamina D En La Resistencia a La Insulina En Escolares Y Adolescentes Con Obesidad","VD","Inclusion Criteria:\n\n* Male and female participants.\n* Participants aged between 10 and 18 years.\n* Obesity as defined by a Body Mass Index (BMI) in the \\>95th percentile according to the World Health Organization's age and sex-specific tables.\n* Willingness to participate in the study.\n* Residency in Mexico City.\n\nExclusion Criteria:\n\n* Patients with comorbidities not attributable to obesity, such as chronic kidney disease, heart failure, liver cirrhosis, etc.\n* Patients with Prader-Willi syndrome, Albright's hereditary osteodystrophy, Borjesson-Forssman-Lehmann syndrome.\n* Patients currently taking vitamin supplements.\n* Patients undergoing pharmacological treatment for obesity.\n* Patients who already present insulin resistance and, although they have not previously received medication, are currently indicated for pharmacological treatment with metformin.",{"count":586,"type":23},40,[158],"Introduction: Vitamin D deficiency is commonly observed in patients with obesity, primarily due to sequestration by adipose tissue. Recent research highlights the importance of this deficiency, showing a correlation between low vitamin D levels and mechanisms contributing to insulin resistance.\n\nObjectives: This study aims to compare the effects of supplementing with 4,000 IU of vitamin D versus 1,000 IU over six months on insulin resistance and the leptin\u002Fadiponectin ratio in school-aged children and adolescents with obesity.\n\nMaterials and Methods: A controlled clinical trial will be conducted involving 40 children with obesity aged 10 to 18 years (BMI \\>95th percentile). Participating children and their parents will undergo measurements such as weight, height, BMI, body fat, and Tanner stage. All participants will receive dietary and physical activity recommendations based on WHO guidelines. After initial assessments, participants will be randomly assigned to receive either 4,000 IU or 1,000 IU of vitamin D. They will be monitored monthly for capsule intake and adverse effects, with follow-up measurements of anthropometry, leptin, adiponectin, insulin \\& lipid profile.\n\nStatistical Analysis: Baseline characteristics will be compared using t-Student or U-Mann Whitney tests, depending on variable distribution. The intervention's impact will be assessed by calculating deltas for body fat and biochemical measurements, with significance tested using paired t-tests or Wilcoxon tests. Covariance analysis (ANCOVA) will be used to adjust for confounding variables.",[590,322,29],"Vitamin D",[592,593,594,595,596,293],"vitamin D","insulin resistence","obesity","leptin","adiponectin","2025-03-21",{"date":242,"type":38},{"date":600,"type":38},"2025-03-01",{"date":400,"type":23},{"name":603,"class":604},"Coordinación de Investigación en Salud, Mexico","OTHER_GOV",{"id":606,"slug":607,"hasResults":12,"nctId":608,"briefTitle":609,"officialTitle":610,"acronym":4,"eligibilityCriteria":611,"healthyVolunteers":17,"sex":55,"minAge":413,"maxAge":154,"enrollmentInfo":612,"targetDuration":4,"studyType":59,"phases":614,"briefSummary":615,"conditions":616,"keywords":620,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":625,"lastUpdatePostDateStruct":626,"startDateStruct":628,"completionDateStruct":630,"leadSponsor":632,"locationsCount":46},"100514350","increasing-food-literacy-in-preschoolers-to-reduce-obesity-risk-100514350","NCT05977348","Increasing Food Literacy in Preschoolers to Reduce Obesity Risk","Increasing Food Literacy as a Means of Increasing Preschool Children's Food Acceptance and Reducing Obesity Risk","Inclusion Criteria:\n\n* Preschool children enrolled in participating centers\n\nExclusion Criteria:\n\n* Severe food allergies that prevent children from consuming project foods\n* Presence of a developmental or sensory disability that affects food intake and\u002For learning\n* Lack of English fluency (children and caregivers)\n* Children not regularly present during days\u002Ftimes that intervention lessons are delivered\n* Parents who are not involved in feeding\u002Fpreparing meals for children at least 50% of the time",{"count":613,"type":23},770,[158],"The goal of this clinical trial is to examine the effects of a nutrition education program on preschool children's food literacy and food acceptance, and to examine the added influence of a healthy eating curriculum and parent education on children's food knowledge and healthful food choices. The project will be evaluated with 450 children ages 3 to 5 years in center-based childcare programs serving predominantly Supplemental Nutrition Assistance Program (SNAP)-eligible families in Pennsylvania. Outcomes for children who receive the added healthy eating curriculum will be compared to children in classrooms that only receive the nutrition education program.",[617,618,619,29],"Food Preferences","Food Selection","Eating, Healthy",[621,622,623,624],"Food literacy","Healthy growth","Child Development","Food Acceptance","2025-03-12",{"date":627,"type":38},"2025-03-17",{"date":629,"type":38},"2023-10-03",{"date":631,"type":23},"2026-08",{"name":103,"class":45},{"id":634,"slug":635,"hasResults":12,"nctId":636,"briefTitle":637,"officialTitle":638,"acronym":639,"eligibilityCriteria":640,"healthyVolunteers":17,"sex":55,"minAge":448,"maxAge":4,"enrollmentInfo":641,"targetDuration":4,"studyType":59,"phases":643,"briefSummary":644,"conditions":645,"keywords":648,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":655,"lastUpdatePostDateStruct":656,"startDateStruct":658,"completionDateStruct":660,"leadSponsor":662,"locationsCount":46},"100518251","phase-2-a-novel-obesity-prevention-program-for-high-risk-infants-in-primary-care-100518251","NCT06028113","A Novel Obesity Prevention Program for High-Risk Infants in Primary Care","A Novel Obesity Prevention Program for High-Risk Infants in Pediatric Primary Care: The THRIVE Randomized Controlled Trial","THRIVE","Inclusion Criteria:\n\n* born 2500 grams or greater\n* delivery occurring between 37 and 42 weeks gestation\n* English speaking\n* infant receiving care provided at our pediatric primary care setting\n* from a racial \u002F ethnic minority group (i.e., non-white, or Hispanic or Latinx) and\u002For economically marginalized background (i.e., household income at or below 138% of federal poverty level; qualifying for Medicaid)\n\nExclusion Criteria:\n\n* care in the Neonatal Intensive Care Unit (\\>7 days)\n* infant congenital anomaly or neonatal condition that affects feeding (e.g., cleft lip\u002Fpalate, metabolic disease)\n* infant exposure to illicit drugs in utero \\[with the exception of tetrahydrocannabinol (THC)\\]\n* diminished or impaired caregiver cognitive functioning\n* family intent to move from the area within 1 year",{"count":642,"type":23},144,[417],"The goal of this clinical trial is to test a responsive parenting obesity prevention program with infants and caregivers of color (e.g., non-White; Hispanic\u002FLatinx) and\u002For who are economically marginalized (i.e., publicly insured), delivered via Integrated Behavioral Health (IBH) in pediatric primary care. The main questions it aims to answer are:\n\n* 1\\) Is the obesity prevention intervention delivered via IBH in pediatric primary care feasible and acceptable to families of color and\u002For families who are economically marginalized?\n* 2\\) Will it prevent rapid weight gain during infancy?\n\nParticipants will complete baseline (newborn), post-treatment (9 months), and follow-up assessments (12 months). Participants assigned to treatment will receive 4 prevention sessions as part of their typical well-child visit in pediatric primary care. Researchers hypothesize that infants in the obesity prevention intervention will have stable weight gain compared to infants in the control group (treatment as usual) will experience more rapid weight gain.",[89,29,646,647],"Weight Gain","Weight Gain Trajectory",[291,649,650,651,652,653,288,654],"infancy","integrated primary care","integrated behavioral health","responsive parenting","responsive feeding","soothing","2025-03-03",{"date":657,"type":38},"2025-03-05",{"date":659,"type":38},"2023-10-05",{"date":661,"type":23},"2026-01-30",{"name":663,"class":45},"Children's Hospital Medical Center, Cincinnati",{"id":665,"slug":666,"hasResults":12,"nctId":667,"briefTitle":668,"officialTitle":669,"acronym":4,"eligibilityCriteria":670,"healthyVolunteers":17,"sex":55,"minAge":202,"maxAge":56,"enrollmentInfo":671,"targetDuration":4,"studyType":59,"phases":673,"briefSummary":674,"conditions":675,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":678,"lastUpdatePostDateStruct":679,"startDateStruct":681,"completionDateStruct":683,"leadSponsor":685,"locationsCount":46},"100558094","a-structured-school-based-health-intervention-for-the-obesity-prevention-100558094","NCT06546644","A Structured School-based Health Intervention for the Obesity Prevention","Effect of a Structured School-based Health Intervention for Obesity Prevention In Children Aged 5-12 Years","Inclusion Criteria:\n\n* Children of age between 5 to 12 years.\n* Enrollment at one of the selected schools.\n\nExclusion Criteria:\n\n* Children and their parents who did not give assent and consent to participate in the study.",{"count":672,"type":23},1200,[158],"The proposed research aims to assess how well a structured intervention is intended to reduce childhood obesity. The intervention addresses food and physical activity behaviors, important determinants of obesity, by concentrating on these elements. The goal of nutritional and physical education is to raise knowledge about the negative effects of obesity and encourage healthy eating habits in children and their caregivers. These educational campaigns will be delivered primarily through schools, guaranteeing a wide audience and consistent messaging.",[676,677,29],"Child Obesity","Child Behavior","2024-08-07",{"date":680,"type":38},"2024-08-09",{"date":682,"type":23},"2024-08-15",{"date":684,"type":23},"2025-04-15",{"name":686,"class":45},"Universiti Putra Malaysia"]