[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obesity-control\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obesity-control":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100595724","phase-3-efficacy-and-safety-of-semaglutide-injection-vs-wegovy-in-chinese-obese-patients-100595724",false,"NCT07036172","Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese Patients","A Multicenter, Randomized, Open-label, Parallel-controlled Phase III Clinical Study Comparing the Efficacy and Safety of Semaglutide Injection and WEGOVY® in Chinese Obese Patients","Inclusion Criteria:\n\n1. Male or female, aged ≥18 years and ≤75 years at the time of signing informed consent；\n2. BMI ≥28 kg\u002Fm2；\n3. A self-reported change in body weight no more than 5% within 90 days before screening.\n\nExclusion Criteria:\n\n1. History of type 1 and type 2 diabetes;\n2. Previous or planned (during the trial period) obesity treatment with surgery or a weight-loss device;\n3. History or presence of chronic or acute pancreatitis;\n4. Personal or first-degree relative(s) history of multiple endocrine neoplasia type 2 or medullary thyroid carcinoma;\n5. A history or presence of suspected depression or other mental disorders;\n6. Patient Health Questionnaire-9 score of ≥15 at screening\n7. Uncontrolled hypertension, any of the following: myocardial infarction, stroke, hospitalisation for unstable angina, or transient ischaemic attack within the past 6 months prior to screening;\n8. History of malignant neoplasms within the past 5 years prior to screening;","ALL","18 Years","75 Years",{"count":20,"type":21},460,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","This is a 48-week randomized, open-label, parallel-controlled biosimilar comparison study comparing the efficacy, safety and immunogenicity of the investigational drug and WEGOVY® in patients with obesity. Eligible participants will be screened and randomized to the experimental group and the active comparator group at a ratio of 1:1 , semaglutide injection or WEGOVY® injection will be given once weekly for 44 weeks, following by a safety follow up of 4 weeks. All participants received a lifestyle intervention that involved counselling on diet and physical activity.",[27],"Obesity Control","RECRUITING","2025-06-16",{"date":31,"type":32},"2025-06-25","ACTUAL",{"date":34,"type":32},"2025-01-03",{"date":36,"type":21},"2026-05",{"name":38,"class":39},"Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.","INDUSTRY",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":50,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":40},"100574305","effect-of-vegetables-on-weight-status-of-university-population-100574305","NCT06757556","Effect of Vegetables on Weight Status of University Population","Effect of Consumption of Non-starchy Vegetables on Weight Status of Overweight and Obese University Population","Inclusion Criteria:\n\n* Overweight and obese individuals with BMI 23kg\u002Fm\\^2\n* Population of UVAS (students, teaching and non-teaching staff)\n\nExclusion criteria:\n\n* Normal weight and underweight individuals with BMI \\\u003C23kg\u002Fm\\^2\n* Non-UVAS (University of Veterinary and Animal Sciences) population.",{"count":49,"type":21},40,[51],"NA","Obesity rates have more than doubled globally since 1990, with 2.5 billion overweight adults by 2022, and 890 million of them living with obesity (WHO, 2023). In Pakistan, approximately 30% of adults are overweight or obese, with 21% overweight and 9% obese. Non-communicable diseases now account for 58% of deaths in the country. WHO recommends daily consumption of non-starchy vegetables to aid weight loss and reduce BMI and fat mass, especially for overweight and obese individuals. This randomized controlled trial (RCT) will be conducted at the University of Veterinary and Animal Sciences (UVAS) in Lahore, Pakistan, targeting the university population, including students, teaching, and non-teaching staff with BMI ≥23 kg\u002Fm². A total of 40 participants will be recruited, with 20 assigned to the intervention group (receiving 2-3 cups of non-starchy vegetables daily) and 20 to the control group (receiving only dietary guidelines). Weight, BMI, and fat mass will be measured before and after the trial using an InBody 270. The data will be analyzed using SPSS version 25, with paired and independent t-tests to compare changes within and between groups. Multiple logistic regression will examine the relationship between vegetable consumption and changes in weight, BMI, and fat mass. This study aims to assess the impact of daily non-starchy vegetable intake on the weight, BMI, and fat mass of the overweight and obese university population.",[27,54],"Overweight and Obese Adults","NOT_YET_RECRUITING",{"date":57,"type":32},"2025-01-07",{"date":59,"type":21},"2025-02-17",{"date":61,"type":21},"2025-09-08",{"name":63,"class":64},"University of Veterinary and Animal Sciences, Lahore - Pakistan","OTHER"]