[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obesity-overweight\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obesity-overweight":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100603809","fast-in-bed-tracking-fit-system-lifestyle-intervention-is-a-clinical-trial-of-a-bed-scale-device-overweight-wheelchair-users-will-participate-in-a-weight-loss-program-half-will-receive-bed-scales-and-participants-who-receive-the-bed-scales-are-expected-to-have-increased-weight-loss-100603809",false,"NCT07141342","Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Participate in a Weight Loss Program, Half Will Receive Bed Scales, and Participants Who Receive the Bed Scales Are Expected to Have Increased Weight Loss.","The Fast In-Bed Tracking (FIT) System Lifestyle Intervention","Inclusion Criteria:\n\n* Age18 +\n* Live within approximately 75 miles of Pittsburgh\n* Uses a wheelchair as primary means of locomotion\n* Currently transfers in and out of bed every night (or most nights)\n* Has been diagnosed as obese or overweight\n* Are interested in losing weight\n* BMI in the range of approximately 25 to 40; BMI range will be determined from published evidence for the primary diagnosis of the participant. For example, spinal cord injury \u002Fquadriplegic BMI range of approximately 22 to 40; for amputees it will be based on location and level of amputation, or if no diagnosis specific evidence exists, a BMI of approximately 25 to 40 will be used as a general guideline.\n* Own a smart phone, and have reliable internet and wifi connection\n* Are comfortable using exercise equipment like resistance bands or hand pedal exercisers\n* Are able and willing to engage in exercise of moderate intensity\n* Weight in bed including sleep partner is an estimated combined weight of 600 pounds or less\n* Does not have a regular way to weigh themselves, such as a roll-on scale in the home or gym, or have regular access to a device to weigh themselves regularly and are willing to avoid weighing themselves during the trial.\n* Indication that the participant has autonomy in decision-making as determined by the \"Everyday Autonomy Self-Determination Scale.\"\n* Indication that their current bedroom setup is compatible with the FIT bed scales as determined by the \"Bed Determination Survey.\"\n\nDue to the medical complexity of this population, inclusion of this study based on BMI, in-bed transfer frequency, or geographic location will be at the discretion of the expert members of our study team and will be considered on a case-by-case basis.\n\nExclusion Criteria:\n\n* Extended vacations or absences planned in the next year (more that 2 - 4 weeks) or plans to move approximately 75 miles or greater from the Pittsburgh region\n* BMI outside of the desired range as based on condition and as determined by the study team.\n* Currently taking weight loss medication, medications that affect appetite, or have had weight loss surgery in the last 2 years.\n* History disordered eating in the last 2 years, such as Anorexia Nervosa, Bulimia Nervosa or Binge Eating Disorder\n* Currently pregnant or intend to become pregnant in the next 12 months\n* Regularly have 4 or more alcoholic drinks a day\n* Have any cognitive conditions that limit decision making or self-governing.\n* Indication that the participant does not have autonomy in decision-making as determined by the \"Everyday Autonomy Self-Determination Scale.\"\n* Indication that their current bedroom setup is not compatible with the FIT bed scales as determined by the \"Bed Determination Survey.\"\n\nDue to the medical complexity of this population, exclusion from this study based on BMI, geographic location, and what is considered a \"medication that affects appetite\" will be at the discretion of the expert members of our study team and will be considered on a case-by-case basis.","ALL","18 Years",{"count":19,"type":20},92,"ESTIMATED","INTERVENTIONAL",[23],"NA","This project will complete the final design and development steps to commercialize the Fast In-Bed Tracking (FIT) Platform, which is an e-Health and wellness Internet of Things (IoT) monitoring system that can be integrated into a user's bed and provide person-centered, real-world outcomes to support health and wellness. The technical feasibility of FIT was proven over the past several years and has demonstrated the platform can support the treatment of several chronic conditions across different populations, including obesity, congestive heart failure, and pressure injuries. The project goals will be to (1) complete design refinements for FIT and (2) demonstrate the platform's efficacy to support weight loss goals of wheelchair users. Wheelchair users are twice as likely as the general population to be overweight or obese and excess weight not only exacerbates mobility and participation limitations but increases risk for secondary health problems. Evidence reveals that frequent weight monitoring is a key driver for weight management, which puts wheelchair users at a significant disadvantage, because they have no convenient way to measure their body weight. As a recent example, lack of participant's ability to self-weigh was a noted limitation to a weight loss program for wheelchair users, known as the Group Lifestyle Balance weight loss program Adapted for Individuals with Impaired Mobility (GLB-AIM). FIT solves this challenge by passively monitoring a user's weight when they get on and off their bed. The investigators lab and community-based feasibility trials demonstrated that FIT successfully tracks weight for individuals and couples sharing a bed and that users find FIT highly usable. This proposed project will allow the investigators to complete the design refinements participants recommended during our community-based feasibility trial and subsequently examine the efficacy of FIT in supporting the weight-loss goals of community-dwelling wheelchair users through a randomized controlled trial using the GLB-AIM.",[26,27,28],"Disability Physical","Wheelchair","Obesity; Overweight",[27,30,31,32,33,34,35,36],"Wheelchair Users","Weigh loss","Weight loss device","Weight loss program","device research","bed scale","Wheelchair Scale","RECRUITING","2026-02-20",{"date":40,"type":41},"2026-02-23","ACTUAL",{"date":43,"type":41},"2026-02-16",{"date":45,"type":20},"2027-09",{"name":47,"class":48},"Jonathan Pearlman","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":21,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":49},"100601594","tdcs-intervention-in-breast-cancer-survivors-with-and-without-obesity-reporting-cognitive-impairment-100601594","NCT07112521","tDCS Intervention in Breast Cancer Survivors With and Without Obesity Reporting Cognitive Impairment","Evaluating the Efficacy of Home-Based tDCS for Cancer-Related Cognitive Impairment and Its Moderation by Obesity: A Double-Blind Randomized Controlled Trial.","LUMINA-brain","Inclusion Criteria:\n\n* Female\n* Over 18 years old\n* Diagnosed with primary adult-onset breast cancer within the last 5 years\n* Completed all active cancer treatments at least 3 months prior to study participation\n* Capable of fulfilling study requirements, including having internet access.\n* Fluent in either Finnish or English\n* Have normal or corrected vision and hearing\n* Right-handed (based on the Edinburgh Handedness Inventory score; Oldfield, 1971)\n\nExclusion Criteria:\n\n* Have received primary cancer treatment (chemotherapy, radiotherapy, immunotherapy, or surgery) within the last 3 months\n* Have a history of childhood-onset cancer\n* Present with acute eczema on the scalp\n* Diagnosed with dementia, Alzheimer's disease, multiple sclerosis, or - Parkinson's disease\n* Have experienced unconsciousness for more than five minutes due to a head\u002Fbrain injury within the last 10 years\n* Have a history of stroke or transient ischemic attack\n* Suffer from claustrophobia\n* Are pregnant or breastfeeding\n* Have any of the following medical implants or devices: cardiac implantable electronic devices, metallic intraocular foreign bodies, neurostimulation systems, cochlear\u002Fear implants, drug infusion pumps, catheters with metal components, metallic fragments (e.g., bullets), cerebral aneurysm clips, magnetic dental implants, tissue expanders, artificial limbs, non-removable piercings, or face tattoos.\n* Weight exceeding 250 kg (the MRI table weight limit) or they are unable to fit within the 70 cm diameter bore of the MRI machine","FEMALE",{"count":60,"type":20},40,[23],"The goal of this intervention is to investigate whether transcranial Direct Current Stimulation (tDCS) can alleviate Cancer-Related Cognitive Impairment (CRCI) in breast cancer survivors, as measured by changes in brain structures and cognitive performance. To assess the efficacy of tDCS, the investigators will compare outcomes between participants receiving active stimulation and those receiving sham stimulation (a placebo condition where participants believe they are receiving stimulation, but are not).\n\nParticipants will:\n\n* Undergo a baseline MRI session\n* Receive either active or sham tDCS for six weeks\n* Undergo a follow-up MRI session\n* Complete cognitive tests and respond to psychosocial questionnaires before, during, and after the tDCS intervention",[64,65],"Breast Cancer Survivor","Obesity, Overweight",[67,68,69,70,71,72],"tdcs","CRCI","breast cancer survivors","obesity","transcranial direct current stimulation","cancer related cognitive impairment","2025-08-29",{"date":75,"type":41},"2025-09-02",{"date":77,"type":20},"2025-09-01",{"date":79,"type":20},"2027-01",{"name":81,"class":48},"University of Helsinki","Obesity \u002FOverweight"]