[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obessive-compulsive-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obessive-compulsive-disorder":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100630213","efficacy-and-influencing-factors-of-mindfulness-based-exposure-group-therapy-for-ocd-100630213",false,"NCT07484750","Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD","Mindfulness-Based Exposure Group Therapy for Obsessive-compulsive Disorder: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Have a primary diagnosis of Obsessive-Compulsive Disorder (OCD) according to DSM-5 criteria\n* Are between 16 and 55 years of age (inclusive)\n* Have a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) total score ≥ 16\n* Have an education level of junior high school or above\n* Are medication-free or have been stabilized on psychotropic medication for at least 8 weeks\n* Have sufficient visual and auditory capabilities to complete study assessments\n* Are willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Meet DSM-5 criteria for any other psychiatric disorder besides OCD\n* Have severe OCD symptoms that prevent completion of assessments\n* Exhibit active suicidal ideation or high suicide risk\n* Have a serious somatic disease, central nervous system disease, or substance abuse history\n* Are pregnant, breastfeeding, or planning pregnancy\n* Have metal implants contraindicated for MRI (e.g., pacemakers, intracranial clips, metal dentures, arterial stents, joint fixations)","ALL","16 Years","55 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Obessive-Compulsive Disorder (OCD) is frequently treatment-refractory and imposes a substantial burden on affected individuals. Although Exposure and Response Prevention (ERP) is widely regarded as the first-line intervention, its inherently distressing nature contributes to treatment refusal and premature dropout in a subset of patients. The present study aims to develop and validate a novel intervention, Mindfulness-Based Exposure Therapy (MBET).\n\nIn contrast to existing protocols that incorporate mindfulness as an adjunct to ERP and have yielded mixed or limited benefits, this study seeks a theoretically grounded integration of mindfulness and exposure-based principles. We hypothesize that mindfulness training improves emotion regulation, thereby producing a synergistic effect that enhances patients' capacity to engage in and complete exposure tasks.\n\nFrom a clinical perspective, MBET is intended to offer a more tolerable and acceptable alternative to standard ERP, with the potential to improve treatment adherence and clinical outcomes among patients who experience traditional exposure procedures as excessively distressing.",[27],"Obessive-Compulsive Disorder",[29,30],"mindfulness","Exposure and Response Prevention","RECRUITING","2026-03-16",{"date":34,"type":35},"2026-03-20","ACTUAL",{"date":37,"type":35},"2026-02-03",{"date":39,"type":21},"2029-06-30",{"name":41,"class":42},"Shanghai Mental Health Center","OTHER"]