[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obscure-gastrointestinal-bleeding\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obscure-gastrointestinal-bleeding":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100599787","endoscopic-evaluation-for-iron-deficiency-anemia-in-patients-on-antithrombotic-therapy-100599787",false,"NCT07089030","Endoscopic Evaluation for Iron Deficiency Anemia in Patients on Antithrombotic Therapy","A Pilot Study Evaluating the Benefit of Endoscopic Assessment for Iron Deficiency Anemia in Patients Receiving Antithrombotic Therapy","BEACON-IDA","Inclusion Criteria:\n\n1. Adult men and postmenopausal women with iron deficiency anemia, and premenopausal women with iron deficiency anemia and a negative gynecological evaluation;\n\n   a. Laboratory-confirmed iron deficiency anemia (hemoglobin \\\u003C 120 g\u002FL for women, \\\u003C 130 g\u002FL for men, and ferritin \\\u003C 30 ng\u002FL);\n2. Patients receiving anticoagulant or antiplatelet therapy\n3. Negative esophagogastroduodenoscopy (EGD), colonoscopy, and capsule endoscopy for gastrointestinal bleeding within six months prior to study enrollment\n4. Willing and able to provide written informed consent\n5. Able to read and understand French\n\nExclusion Criteria:\n\n1. Ongoing overt gastrointestinal bleeding\n2. Acute coronary syndrome, acute neurological event, sepsis, or respiratory failure within the past week\n3. Pregnant women\n4. Known gastrointestinal or hematological malignancy\n5. Contraindications to capsule endoscopy\n6. History of bariatric surgery, gastrectomy, or segmental resection of the small intestine\n7. Inability to take oral iron\n8. Other sources of blood loss (e.g., urinary, gynecological, hematoma, hemolysis)","ALL","18 Years","90 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a single-center, randomized pilot study evaluating the feasibility and safety of two management strategies for patients on antithrombotic therapy who present with obscure gastrointestinal bleeding (OGIB). Participants will be randomized to either repeated endoscopic evaluations or a conservative medical approach with limited testing. The study aims to assess whether conservative management yields similar clinical outcomes and quality of life compared to standard repeated endoscopic procedures. Results will inform the design of a larger trial and address the current lack of guidelines for managing recurrent iron-deficiency anemia in this patient population.",[28,29,30],"Obscure Gastrointestinal Bleeding","Iron-Deficiency Anemia","Antithrombotic Therapy",[28,29,30,32,33,34,35],"Anticoagulants","Antiplatelet Agents","Endoscopy","Gastrointestinal Hemorrhage","RECRUITING","2025-07-25",{"date":39,"type":40},"2025-07-28","ACTUAL",{"date":42,"type":40},"2023-06-06",{"date":44,"type":22},"2026-06-06",{"name":46,"class":47},"Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":48},"100412094","depth-of-maximal-ileal-insertion-during-retrograde-enteroscopy-with-tts-balloon-100412094","NCT04646083","Depth of Maximal Ileal Insertion During Retrograde Enteroscopy With TTS Balloon","Depth of Maximal Insertion During Retrograde Enteroscopy Using Colonoscopy With Through-the-scope Balloon Enteroscopy (NaviAid) Compared With Using the Standard Colonoscope Alone","NaviAid2","Inclusion Criteria:\n\n1. Sign Informed Consent Form\n2. Patients age between 18-90 years\n3. Patients in which retrograde enteroscopy is indicated for any of the following:\n\nabnormal video capsule endoscopy non-diagnostic upper and lower endoscopy obscure gastrointestinal bleeding iron deficiency anemia non-diagnostic upper endoscopy and abnormal CT Hemodynamically stable\n\nExclusion Criteria:\n\n1. Inability to sign Informed Consent Form\n2. Pregnancy and breast feeding\n3. Prior colon resection\n4. Patients with known strictures\n5. Patients with altered anatomy\n6. Inadequate bowel preparation.",{"count":58,"type":22},100,"OBSERVATIONAL","Diagnostic modalities for the evaluation of small bowel pathology include video capsule endoscopy (VCE), antegrade and retrograde device-assisted enteroscopy, CT and MR enterography (1). Despite VCE being the first-line evaluation modality, it lacks interventional capability. Deep enteroscopy (DE) allows tissue sampling and other therapeutic interventions with real-time endoscopic assessment. DE is usually performed with specific endoscopes (balloon-assisted device or spiral overtube) making it time consuming and there is limited availability since special instruments and accessories are required.(1,2) The through-the-scope (TTS) balloon system consists of a balloon catheter designed for anchoring in the small bowel, inserted through the instrument channel of a standard colonoscope.(3) The catheter is advanced, the balloon is inflated and anchored in the small intestine and the endoscope slides over the guiding catheter to the inflated balloon. The most common indications for DE are obscure GI bleeding, iron deficiency anemia, abnormal capsule endoscopy and chronic diarrhea. As compared to spiral, single-or double-balloon enteroscopy, TTS (NaviAid, SMART Medical Systems Ltd, Ra'anana, Israel) is a simpler technique, which requires less investment in infrastructure. The balloon catheter is advanced blindly in front of a standard adult colonoscope as it bends around the curves of the small bowel. To prevent perforation\u002Ftrauma the catheter is fitted with a soft silicone tip which easily bends under pressure.\n\nInsertion depth can be calculated during the withdrawal of the enteroscope. The Aim of the study: To compare the depth of maximal ileal insertion between through-the-scope balloon enteroscopy (NaviAid) with enteroscopy using the adult colonoscope (Olympus CF-190) alone, in the same patient, in a prospective cohort at University Medical Center of El Paso, Texas.",[28,62],"Anemia, Iron Deficiency",[64,65],"retrograde enteroscopy","small bowel bleeding","2025-06-13",{"date":68,"type":40},"2025-06-18",{"date":70,"type":40},"2021-01-14",{"date":72,"type":22},"2025-12-31",{"name":74,"class":47},"Texas Tech University Health Sciences Center, El Paso"]