[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obstetric-labor-complications\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obstetric-labor-complications":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,51,85,111,134,164,185,212],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100639928","postnatal-debriefing-after-adverse-obstetric-events-100639928",false,"NCT07579273","Postnatal Debriefing After Adverse Obstetric Events","Effect of a Structured Postnatal Debriefing on Psychological Outcomes and Birth Experience in Women After Adverse or Unexpected Obstetric Events","DBIRTH","Inclusion Criteria:\n\n* Women aged 18 years or older.\n* Women who have experienced an adverse or unexpected obstetric event during labor or the immediate postpartum period.\n* Admitted to the maternity unit of Hospital del Mar and clinically stable within the first 24 hours postpartum.\n* Able to understand and communicate in Spanish, Catalan, or English.\n* Willing to participate and able to provide written informed consent.\n* Access to an email account for follow-up assessments.\n\nExclusion Criteria:\n\n* Inability to communicate verbally.\n* Maternal-neonatal separation due to social reasons.\n* Unstable or severe psychiatric condition.\n* Immediate perinatal loss (intrapartum fetal death or early neonatal death).\n* Admission to intensive care within the first 24 hours postpartum.","FEMALE","18 Years",{"count":20,"type":21},142,"ESTIMATED","INTERVENTIONAL",[24],"NA","Adverse or unexpected obstetric events can negatively affect women's psychological well-being and childbirth experience, increasing the risk of postpartum traumatic stress. However, structured postnatal debriefing is not routinely implemented in clinical practice, and evidence regarding its effectiveness remains limited.\n\nThis study aims to evaluate the effect of a structured postnatal debriefing conducted within the first 24 hours after childbirth in women who have experienced an adverse or unexpected obstetric event.\n\nThis quasi-experimental pretest-posttest study will include two consecutive groups: a control group receiving usual postpartum care during the pre-implementation phase and an intervention group receiving structured postnatal debriefing during the implementation phase.\n\nThe primary outcome is childbirth-related trauma at 6 weeks postpartum. Secondary outcomes include birth satisfaction, early post-traumatic stress symptoms, satisfaction with information and emotional support received after childbirth, and clinical maternal and neonatal outcomes.\n\nThis study will provide evidence on whether structured postnatal debriefing improves psychological outcomes and contributes to more patient-centered obstetric care.",[27,28,29,30],"Stress Disorders, Post-Traumatic","Psychological Trauma","Obstetric Labor Complications","Postpartum Period",[32,33,34,35,36,37,38],"Traumatic Birth","Birth Experience","Postpartum PTSD","Postnatal Debriefing","Obstetric Debriefing","Patient-Centered Care","Maternal Mental Health","NOT_YET_RECRUITING","2026-06-22",{"date":42,"type":43},"2026-06-25","ACTUAL",{"date":45,"type":21},"2026-10",{"date":47,"type":21},"2029-01",{"name":49,"class":50},"Parc de Salut Mar","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":84},"100459604","the-periviable-goals-decision-support-tool-100459604","NCT05264779","The Periviable GOALS Decision Support Tool","Promoting Shared Decision Making in Periviable Care: A Randomized Controlled Trial of the Periviable GOALS Decision Support Tool","Inclusion Criteria for Pregnant Persons:\n\n* Adults (18 years or older)\n* Pregnant between 22 0\u002F7 to 25 6\u002F7 weeks gestation (this window may be slightly different for each recruitment site, as the gestational window that defines periviable delivery varies by institution).\n* Presenting to Labor \\& Delivery at an approved study site with a pregnancy complication that poses the potential threat of or need for periviable delivery (e.g., rupture of membranes, preterm labor, shortened cervix, pre-eclampsia, and growth restriction).\n* Must have been counseled on their neonatal treatment options (e.g. resuscitation, comfort care) by their healthcare team prior to being approached by the study team.\n\nInclusion Criteria for Important Others:\n\n* Adults (18 years or older)\n* 1 per pregnant person\n* Is identified by the pregnant person as someone who will be involved in making decisions for the baby\n* Must be present at the time of randomization to participate\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Incarcerated\n* Medically unstable (i.e. in active labor and dilated 6cm or more)\n* Emotionally unstable\n* Have not been counseled by their healthcare team regarding neonatal treatment options\n* Are not admitted to Labor \\& Delivery for reasons indicative of a threatened early delivery\n* If they are experiencing a known fatal fetal anomaly\n* Are not present at the time of randomization (only for important others)","ALL",{"count":60,"type":21},300,[24],"The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery (deliveries occurring between 22 0\u002F7 - 25 6\u002F7 weeks gestational age). It is designed for parents to review independent of their clinician, and is intended to supplement, not replace, clinician counseling. The focus of the DST is the provision of patient-centered outcomes information and assistance with values clarification regarding neonatal outcomes. This is a multisite, randomized controlled trial to test the effect of the Periviable GOALS DST on shared decision making and decision satisfaction. The investigators hypothesize that participants who utilize the GOALS DST will have improved shared decision making and higher decision satisfaction.",[64,65,66,67,29],"Pregnancy Preterm","Premature Birth","Pregnancy Complications","Obstetric Labor, Premature",[69,70,71,72,73],"Decision making","Periviable delivery","Preterm birth","Risk Communication","Neonatal Resuscitation","RECRUITING","2026-05-06",{"date":77,"type":43},"2026-05-11",{"date":79,"type":43},"2022-06-06",{"date":81,"type":21},"2027-02",{"name":83,"class":50},"Indiana University",12,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":96,"briefSummary":97,"conditions":98,"keywords":99,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":110},"100553379","mri-pseudo-ct-sequences-for-obstetrical-pelvimetry-100553379","NCT06485323","MRI Pseudo-CT Sequences for Obstetrical Pelvimetry.","MRI Pseudo-CT Sequences for Obstetrical Pelvimetry","Pelvi-MRI","Inclusion Criteria:\n\n* Pregnant woman 33 to 41 week\n* Woman who gave birth by cesarean section, for whom the obstetrician requests a pelvimetry CT for the next pregnancy\n* Pelvimetry planned by the obstetrical team outside of \"emergency\" pathway\n* Adhere to the study protocol after reading the patient information document have signed the informed consent form to participate in the study\n\nExclusion Criteria:\n\n* Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear implant,…)\n* Severe claustrophobia\n* uncomfortable back position","99 Years",{"count":95,"type":21},95,[24],"It is possible to perform a pelvimetry by MRI as a substitute to pelvimetry by CT, hence sparing the patient from a dose of irradiation.",[29],[100],"technological progress","2026-04-23",{"date":103,"type":43},"2026-04-29",{"date":105,"type":43},"2023-07-05",{"date":107,"type":21},"2026-12-31",{"name":109,"class":50},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain",1,{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":117,"sex":17,"minAge":18,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":123,"conditions":124,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":110},"100497884","early-phase-1-monoferric-for-prenatal-iron-deficiency-100497884","NCT05763043","Monoferric for Prenatal Iron Deficiency","Inclusion Criteria:\n\n* Participants 18 years of age or older between 14 to 42 weeks gestation who are deemed appropriate for IV iron by their treating provider as part of their standard of care treatment.\n* Iron deficiency anemia, defined as second or third trimester (14 weeks or more) hemoglobin less than or equal to 10.5 g\u002FdL or less than or equal to11 g\u002FdL, respectively, and ferritin less than 50 μg\u002FL\n* Experience intolerance to oral iron or are greater than 28 weeks gestation\n* Willing to participate in the study\n\nExclusion Criteria:\n\n* Known infectious, inflammatory, or malignant conditions that may confound iron repletion and outcome analysis\n* Prior IV iron intolerance or hypersensitivity reaction",true,"65 Years",{"count":120,"type":21},80,[122],"EARLY_PHASE1","A prospective observational study of pregnant women with iron deficiency anemia and oral iron intolerance or advanced gestational age.",[29],"2024-09-16",{"date":127,"type":43},"2024-09-19",{"date":129,"type":43},"2024-01-18",{"date":131,"type":21},"2028-10",{"name":133,"class":50},"Oregon Health and Science University",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":117,"sex":17,"minAge":18,"maxAge":142,"enrollmentInfo":143,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":110},"100543339","phase-4-effect-of-intravenous-vitamin-c-on-intrapartum-maternal-fever-after-epidural-labor-analgesia-100543339","NCT06354582","Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia","Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia : A Randomized Controlled Trial","EIVCIMFAELA","Inclusion Criteria:\n\n* single-fetus, head position, and full-term vaginal delivery receiving epidural labor analgesia.\n\nExclusion Criteria:\n\n* have a fever before epidural analgesia, acute infection on admission, incomplete baseline data, fatal fetal malformations or comorbidities, duration from admission to delivery of more than 72 hours or less than 3 hours, or an American Society of Anesthesiologists (ASA) classification of ≥ Ⅲ.","35 Years",{"count":144,"type":21},400,[146],"PHASE4","This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes, and provide a reference for clinical preventive medication.",[29,149],"Fever",[151,152,153,154],"Intrapartum maternal fever","Epidural analgesia","Inflammation","Vitamin C","2024-06-30",{"date":157,"type":43},"2024-07-03",{"date":159,"type":43},"2024-04-15",{"date":161,"type":21},"2024-10",{"name":163,"class":50},"Kunyue Li",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":168,"acronym":4,"eligibilityCriteria":169,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":170,"targetDuration":4,"studyType":172,"phases":4,"briefSummary":173,"conditions":174,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":110},"100485292","doppler-findings-in-the-fetal-cerebral-blood-vessels-vamca-within-24-hours-before-delivery-and-relation-with-perinatal-outcome-100485292","NCT05599178","Doppler Findings in the Fetal Cerebral Blood Vessels (VA\u002FMCA) Within 24 Hours Before Delivery and Relation With Perinatal Outcome.","Inclusion Criteria:\n\n* Singleton pregnancy.\n* Term gestation (37-42 weeks).\n* Fetus in cephalic presentation.\n* No known fetal chromosomal or (severe) congenital anomaly.\n* Normally grown fetus (ultrasound scan demonstrating normal fetal growth between 30-37 weeks of gestation, defined as an estimated fetal weight\u002Fabdominal circumference \\> 10th centile or crossing \\\u003C2 quartiles compared to earlier growth ultrasound).\n* Absence of pre-existing doppler or amniotic fluid abnormalities.\n* Normal fetal heart rate tracing \u002F CTG (excluding pre-existing hypoxia).\n* Admission in early spontaneous labor or induction of labor with expected delivery \\\u003C 24 hours.\n* Maternal age \\>= 18 years\n* Willing to give written informed consent.\n\nExclusion Criteria:\n\n* Advanced labor (\\> 4cm of cervical dilatation) at the time of admission on the labor ward.\n* Severe pre-existing chronic maternal medical condition or poor obstetric history\u002Fantenatal complications associated with increased risk of adverse perinatal outcome (non-exhaustive e.g.: uncontrolled chronic hypertension, severe pre-eclampsia, uncontrolled (gestational) diabetes, maternal sepsis, major antepartum haemorrhage, intra-uterine infection, prolonged rupture of membranes \\> 18 hours, etc.).\n* Intra-uterine fetal demise \u002F death.\n* Prelabour rupture of membranes with meconium-stained amniotic fluid.\n* Patients not fulfilling all the inclusion criteria or refusing to give written informed consent.",{"count":171,"type":21},120,"OBSERVATIONAL","1. Assess differences in flow patterns in the fetal cerebral blood vessels within 24 hours before delivery between fetuses with a normal vs. adverse perinatal outcome.\n2. Explore maternal and\u002For fetal characteristics that might influence technical feasibility of doppler sonography of the fetal cerebral blood vessels in early labor at term.\n3. Assess reliability of the technique by measuring intra- and inter-observer variation in a subset of participants.",[175,29],"Ultrasonography, Doppler","2024-06-28",{"date":178,"type":43},"2024-07-01",{"date":180,"type":43},"2022-12-23",{"date":182,"type":21},"2025-12-31",{"name":184,"class":50},"Universitaire Ziekenhuizen KU Leuven",{"id":186,"slug":187,"hasResults":11,"nctId":188,"briefTitle":189,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":117,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":192,"targetDuration":4,"studyType":22,"phases":194,"briefSummary":195,"conditions":196,"keywords":198,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":110},"100519917","prelabor-visual-biofeedback-by-a-self-operated-ultrasound-device-100519917","NCT06049784","Prelabor Visual Biofeedback by a Self-operated Ultrasound Device","Prelabor Maternal Pushing Training Using Visual Biofeedback by a Self-operated Ultrasound Device","Inclusion Criteria:\n\n* Nuliparity\n* Singleton pregnancy\n* Planned for vaginal delivery\n* Low risk pregnancy\n* Ability to fulfill a questionnaire\n\nExclusion Criteria:\n\n* Multifetal gestation\n* Contraindications for vaginal delivery (Placenta previa, Breech presentation etc.)\n* High risk pregnancy",{"count":193,"type":21},261,[24],"A substantial number of women report fear of childbirth and negative birth experiences. The objective of the study is to assess the efficacy of visual biofeedback before labor using a self-operated home ultrasound for maternal pushing training, which is expected to reduce fear of childbirth, increase perceived control during birth, prevent prolonged labor and the ensuing maternal and neonatal negative adverse outcomes, and prevent maternal post-traumatic stress symptoms. Intrapartum visual biofeedback provided by obstetricians during the second stage of labor has been shown to increase pushing efficiency and improve maternal obstetric and psychological outcomes. Previously, visual biofeedback has been implemented only in an in-hospital setting and, with one known exception, only during labor. A Mobile Self-Operated Home Ultrasound System has been reported as a feasible and reliable tool for obstetrical ultrasound. A randomized controlled trial will be conducted with three study groups of pregnant women (37-39 weeks of gestation): (1) Obstetrical ultrasound+visual biofeedback in-hospital and at home using self-operated ultrasound; (2) Obstetrical ultrasound+visual biofeedback in-hospital; (3) Obstetrical ultrasound only. Visual biofeedback by ultrasound will be performed by transperineal ultrasound, enabling the future mother to visualize the descent of the fetal head within the birth canal in response to her pushing effort. Follow-up will be conducted two weeks later and at six weeks postpartum. Positive results following the application of biofeedback by self-operated home ultrasound may change the paradigm for pre-labour sonographic education. Self-operated home ultrasound will also enable more comprehensive pre-labor ultrasound-based education and hopefully reduce adverse physical and psychological outcomes following childbirth.",[29,197],"Obstetric Trauma",[199,200,201,202],"Visual Biofeedback","Self Operated Ultrasound device","Second stage of labor","Trans Perineal Ultrasound","2024-05-02",{"date":205,"type":43},"2024-05-06",{"date":207,"type":43},"2023-12-31",{"date":209,"type":21},"2026-12",{"name":211,"class":50},"Rabin Medical Center",{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":117,"sex":58,"minAge":218,"maxAge":219,"enrollmentInfo":220,"targetDuration":4,"studyType":172,"phases":4,"briefSummary":222,"conditions":223,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":110},"100349520","shenzhen-birth-cohort-study-100349520","NCT03830879","Shenzhen Birth Cohort Study","Inclusion Criteria:\n\n* 1\\. Pregnant women plan to delivery and participate in child care in our hospital; 2. Pregnant women plan to reside in Shenzhen for at least 7 years; 3. Pregnant women who show interest in the study and agree to provide informed consent; 4. Gestational weeks are less than 20 weeks.Those who will agree that their neonatal will be included in the study and be followed up regularly in our child health clinic until an age of 7 years.\n\nExclusion Criteria:\n\n* Pregnant women who have been pregnant for more than 20 weeks; refuse to participate; unable to guarantee delivery in our hospital or can't participate in child care in our hospital; mentally incapacitated and need guardians; or be unwilling to sign informed consent.","15 Years","49 Years",{"count":221,"type":21},10000,"The Shenzhen Birth Cohort Study was set up to investigate the effect of early life environmental exposures on short- and long-term health consequences in Shenzhen, China.",[66,224,29,225,226],"Gestational Diabetes","Neurodevelopmental Disorders","Childhood Obesity","2019-02-01",{"date":229,"type":43},"2019-02-05",{"date":231,"type":43},"2018-03-06",{"date":233,"type":21},"2032-12-31",{"name":235,"class":50},"Sun Yat-sen University"]